Racial Differences in Systemic Immune Parameters in Individuals With Lung Cancer by Mitchell S. von Itzstein, MD, Jialiang Liu, PhD, Hong Mu-Mosley, PhD, Farjana Fattah, PhD, Jason Y. Park, MD, PhD, Jeffrey A. SoRelle, MD, J. David Farrar, PhD, Mary E. Gwin, MD, David Hsiehchen, MD, Yvonne Gloria-McCutchen, Edward K. Wakeland, PhD, Suzanne Cole, MD, Sheena Bhalla, MD, Radhika Kainthla, MD, Igor Puzanov, MD, MSCI, Benjamin Switzer, DO, MHSA, MS, Gregory A. Daniels, MD, PhD, Yousef Zakharia, MD, Montaser Shaheen, MD, Jianjun Zhang, MD, PhD, Yang Xie, PhD, David E. Gerber, MD

“…Compared with White patients, Black patients had greater comorbidity (median Charlson Comorbidity Index 5 versus 3; p = 0.04) and were more likely to have received previous chemotherapy (79% versus 47%; p = 0.03). …”
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The role of VNTR aggrecan gene polymorphism in the development of osteoarthritis in women by D. A. Shapovalova, A. V. Tyurin, S. S. Litvinov, E. K. Khusnutdinova, R. I. Khusainova

“…Solving the problem of comorbidity of OA and uCTD signs will contribute to the early diagnosis and prophylactics of OA. …”
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Cholecystostomy as Bridge to Surgery and as Definitive Treatment or Acute Cholecystectomy in Patients with Acute Cholecystitis by Agnieszka Popowicz, Lars Lundell, Peter Gerber, Ulf Gustafsson, Emil Pieniowski, Helen Sinabulya, Krister Sjödahl, Andrianos Tsekrekos, Gabriel Sandblom

“…After adjusting for age, gender, Charlson comorbidity index, and degree of cholecystitis, the hospital stay was significantly longer for patients treated with PC than for those undergoing acute cholecystectomy (P<0.001) but the risk for intervention-related complications was found to be significantly lower (P=0.001) in the PC group. …”
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Risk of myocardial infarction (MI) and death following MI in people with chronic obstructive pulmonary disease (COPD): a systematic review and meta-analysis by Jennifer K Quint, Liam Smeeth, Kieran J Rothnie, Ruoling Yan

“…Objectives Cardiovascular disease is an important comorbidity in patients with chronic obstructive pulmonary disease (COPD). …”
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Risk factors of chronic kidney disease in cisplatin-based hyperthermia intraperitoneal chemotherapy by Chih-Chung Cheng, Hung-Chieh Yeh, Pei-Wen Su, Chien-Lin Ho, Sheng-Chi Chang

“…This study aims to investigate the incidence of CKD following cisplatin-based HIPEC and to analyse the associated risk factors.Materials and Methods From January 2016 to August 2021, a total of 55 patients treated with CRS and cisplatin-based HIPEC for peritoneal carcinomatosis were categorized retrospectively into groups, with and without CKD. Demographics, comorbidity, surgery, postoperative management, and complications were collected to evaluate risk factors for cisplatin-based HIPEC-related CKD. …”
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The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetes by Avia Paz, Kareem Midlej, Osayd Zohud, Iqbal M. Lone, Fuad A. Iraqi

“…Conclusions Our study establishes a foundation for future quantitative trait loci mapping using CC lines and identifying genes underlying the comorbidity of Alzheimer's disease (AD), caused by obesity and T2D. …”
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Validation Spanish of the Post-Traumatic Stress Disorder Scale in the Postpartum - City BITS by Ayelén Acosta, Aquiles Pérez Delgado, Mercedes Lotufo, Angela Zayas, Sandro Giovanazzi

“…Four symptom clusters have been identified: re-experiencing, avoidance, negative cognitions and mood, and hyperarousal symptoms. Despite its high comorbidity with depression and anxiety, postpartum PTSD remains underdiagnosed in maternal settings. …”
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Machine learning-driven prediction of medical expenses in triple-vessel PCI patients using feature selection by Kuan-Yu Chen, Yen-Chun Huang, Chih-Kuang Liu, Shao-Jung Li, Mingchih Chen

“…The top variables included 1-year medical expenditure before PCI surgery (hospitalization and outpatient costs), average blood transfusion volume, ventilator use duration, Charlson Comorbidity Index scores, emergency department visits, and patient age. …”
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Prevalence, Awareness, Treatment, and Control of Hypertension among Saudi Adult Population: A National Survey by Abdalla A. Saeed, Nasser A. Al-Hamdan, Ahmed A. Bahnassy, Abdelshakour M. Abdalla, Mostafa A. F. Abbas, Lamiaa Z. Abuzaid

“…Awareness was significantly associated with gender, age, geographical location, occupation, and comorbidity. Applying drug treatment was significantly more among older patients, but control was significantly higher among younger patients and patients with higher level of physical activity. …”
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Acute kidney injury, the present on admission (POA) indicator and sex disparities: observational study of inpatient real-world data in a Swiss tertiary healthcare system. Explorati... by Michael Simon, Sarah N Musy, Karen Triep, Olga Endrich

“…However, for the female population mortality was higher (stage III AKI 41.6%).Conclusion Using the POA flag, the results reflect the clinical situation of complications and comorbidities evolving unexpectedly. As our results show sex differences, that is, a lower morbidity of female patients for each stage, but a higher mortality, a deeper evaluation of the implied sex differences in staging of KD should follow.The general results confirm the necessity of a diagnosis-onset reporting in health statistics.…”
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Association Between Vaso-Occlusive Crises and Opioid Prescriptions Among Patients with Sickle Cell Disease: A Retrospective Claims-Based Study by Hyeun Ah Kang, Jamie C. Barner, Kristin M. Richards, Menaka Bhor, Jincy Paulose, Abdullah Kutlar

“…Covariates included age, gender, nonopioid medication use, nonstudy SCD-related medication (penicillin and folic acid) use, evidence of blood transfusions, number of SCD-related complications, number of SCD-related comorbid conditions, and Charlson Comorbidity Index score. …”
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Prevalence of autoimmune thyroid disease in patients with psoriasis: a meta-analysis by Peng Zhang, Ruifang Wu, Xiaochao Zhang, Suhan Zhang, Siying Li, Yuwen Su

“…This meta-analysis aims to determine the association between psoriasis and AITD.Design A meta-analysis of observational studies.Data sources PubMed, EMBASE, Scopus and the Cochrane Library were searched up to 1 November 2021.Eligibility criteria for selecting studies We included non-randomised studies, each with over 50 cases in every group, focusing on the rate of comorbidity between psoriasis and AITD.Data extraction and synthesis Two independent reviewers screened the articles and extracted data. …”
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Poor radiological outcomes and associated factors among tibial shaft fracture patients treated with intramedullary nail fixation at Addis Ababa Burn, Emergency and Trauma Hospital,... by Yohannes Shugie, Samuel Kebede, Fanna Adugna, Dereje Bayissa Demissie, Tilahun Desta

“…The magnitude of poor radiological outcomes among the tibial shaft fracture patients treated with intramedullary nail fixation was 23.1%, with factors including include the presence of medical comorbidity [adjusted odd ratio (AOR) (95% confidence interval, CI): 16.5 (2.524–108.69)], having diabetes mellitus [AOR (95% CI): 3.85 (1.07–14.08)], Gustilo–Anderson type III (GA III) open fractures [AOR (95% CI): 17.4 (3.11–97.72)], and post-operative infection [AOR (95% CI): 13.9 (5.8–33.16)] identified as being significantly associated with poor radiological outcomes.ConclusionThe magnitude of poor radiological outcomes in this study is comparable to other similar studies. …”
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Reexpansion Pulmonary Edema following Laparoscopy-Assisted Distal Gastrectomy for a Patient with Early Gastric Cancer: A Case Report by Kazuhito Yajima, Tatsuo Kanda, Ryo Tanaka, Yu Sato, Takashi Ishikawa, Shin-ichi Kosugi, Tadayuki Honda, Katsuyoshi Hatakeyama

“…A 57-year-old Japanese woman with no preoperative comorbidity was diagnosed with early gastric cancer. …”
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Psychiatric Assessment in Patients with Mild Temporal Lobe Epilepsy by Antonella Bruni, Iolanda Martino, Maria Eugenia Caligiuri, Maria Grazia Vaccaro, Michele Trimboli, Cristina Segura Garcia, Pasquale De Fazio, Antonio Gambardella, Angelo Labate

“…Here, we aimed at studying the personality profile in patients with mild temporal lobe epilepsy (mTLE) with psychiatric comorbidity. Materials and Methods. Thirty-five patients with mTLE (22 males, mean age 40.7±12.1) underwent awake and sleep EEG, 3T brain MRI, and an extensive standardized diagnostic neuropsychiatric battery: Temperament and Character Inventory-Revised (TCI-R), Beck Depression Inventory-2, and State-Trait Anxiety Inventory. …”
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Thyroid Dysfunction Prevalence and Risk Factors in the Southeastern Part of Bangladesh: A Cross‐Sectional Study by Muhammad Shahadat Hossen, Md. Mahmodul Islam, Abhijit Das, Md. Abdur Rahman Ripon, Mohammad Tohidul Amin, Mohammad Anwarul Basher, Md. Mamun Or Rashid

“…Interestingly, the studied population also exhibited higher rates of comorbidities including gastritis, diabetes, and cardiovascular diseases. …”
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Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study by Michael Chen-Xu, Christopher Kassam, Emma Cameron, Szymon Ryba, Vivian Yiu

“…All-cause mortality, LOS and improvement in AKI stage, demographic and comorbidity data, medications and AKI order set use were automatically collected from the EHR.Results The AKI order set was used in 9.8% of AKI events and was associated with 28% lower odds of all-cause mortality (multivariable odds ratio [OR] 0.72, 95% confidence interval [CI] 0.57–0.91). …”
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Development and validation of a novel AI-derived index for predicting COPD medical costs in clinical practice by Guan-Heng Liu, Chin-Ling Li, Chih-Yuan Yang, Shih-Feng Liu

“…The final predictors included interactions such as Age × BMI, alongside Tumor Presence, Number of Comorbidities, Acute Exacerbation frequency, and the DOSE Index. …”
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Cluster analysis of post-COVID-19 physical and mental health outcomes 3–6 months after SARS-CoV-2 infection: results of the French Prospective ALCOVID Cohort Study by Philippe Halfon, Laurent Chiche, Hervé Pegliasco, Stanislas Rebaudet, Thomas Escoda, Hervé Faralli, Frédéric Cohen

“…Multiple component analysis was used to identify clinical phenotypic clusters of PCC patients, as well as their initial comorbidity groups. A multinomial regression model was used to evaluate the association between the initial comorbidities and disease severity with PCC phenotype.Results A total of 210 patients agreed to participate, of which 157 (75%) reported at least one symptom at the 3–6 months visit; mostly asthenia, dyspnoea, psychiatric disorders such as anxiety, depression, post-traumatic stress disorder and cognitive disorders. …”
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Effectiveness and Safety of the Coadministration of Rifampin and Warfarin versus Direct Oral Anticoagulants: A Cohort Study by Ju-Chieh Wung, Chia-Chen Hsu, Chi-En Wang, Yaa-Hui Dong, Chia-Chieh Lin, Szu-Yu Wang, Shih-Lin Chang, Yuh-Lih Chang

“…The median Charlson Comorbidity Index and HAS-BLED (hypertension, abnormal renal/liver function, stroke, bleeding history or predisposition, labile INR, elderly, drugs/alcohol concomitantly) score of the two groups were 2 and 3, respectively. …”
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