Medical Resource Use and Costs of Treating Sickle Cell-related Vaso-occlusive Crisis Episodes: A Retrospective Claims Study by Nirmish Shah, Menaka Bhor, Lin Xie, Jincy Paulose, Huseyin Yuce

“…Of these, 66.5% had a Charlson Comorbidity index (CCI) score of 0 (no comorbidities) and 67.3% were female. …”
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Evaluation of Stroke Patients Diagnosed with Rheumatologic Diseases by Cihat Özgüncü, Şerefnur Öztürk, Gökhan Özdemir

“… Objective: Some comorbid diseases are recognized as specific risk factors for stroke. …”
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Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review by Wei Jin Wong, Tan Van Nguyen, Fahed Ahmad, Huyen Thi Thanh Vu, Angela S. Koh, Kit Mun Tan, Ying Zhang, Christopher Harrison, Mark Woodward, Tu Ngoc Nguyen

“…ABSTRACT Diabetes is one of the most pressing health issues in the Southeast Asian region, and hypertension has been commonly reported as a comorbidity in adults with diabetes. This systematic review aimed to synthesize evidence on the prevalence and management of hypertension in adults with diabetes in Southeast Asian countries. …”
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Seizure-Related Injuries among People with Epilepsy at the Outpatient Department of the University of Gondar Hospital, Northwest Ethiopia: Cross-Sectional Institutional-Based Study by Berhanu Boru Bifftu, Bewket Tadesse Tiruneh, Mengistu Mekonnen Kelkay, Nestanet Habte Bayu, Abebe Woldesellassie Tewolde, Wubet Worku Takele, Mehammed Adem Getnet, Abere Woretaw Azagew

“…The characteristics of epilepsy such as the episodic nature of impairment of consciousness and motor control, psychomotor comorbidity, seizure frequency, and side effects of antiepileptic drugs impact negatively on the physical safety of the patients. …”
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C-Reactive Protein As A Response Indicator In Drug-Naïve Patients With Major Depressive Disorder: A Hospital-Based Study by Ather Muneer, Nargis Munir, Nadia Shams, Mirza Inam, Usman Ghani, Neelam Ayub

“…Patients with first-episode MDD with no history of antidepressant exposure and other medical comorbidity were recruited for pharmacotherapy with escitalopram, a first-line antidepressant. …”
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Long-term Results of Topical Insulin Treatment for Persistent Corneal Epithelial Defects by Júlio Almeida, Tomás Costa, Maria Vivas, Catarina Monteiro, Fernando T. Vaz, Diana Silva, Cristina Vendrell, Isabel Prieto

“…Patients’ demographic information, etiology, comorbidities, and clinical data were reviewed. The rate of epithelial healing was considered as the primary outcome measure. …”
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High Healthcare Utilization in Adolescents with Sickle Cell Disease Prior to Transition to Adult Care: A Retrospective Study by Julie Kanter, Menaka Bhor, Xin Li, Frank Li, Jincy Paulose

“…Outcomes included medications, disease management interventions, Charlson Comorbidity Index (CCI), vaso-occlusive (VOC) crises requiring healthcare visits, HCRU, and SCD complications. …”
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A Comparison of the Outcomes of COVID-19 Vaccinated and Nonvaccinated Patients Admitted to an Intensive Care Unit in a Low-Middle-Income Country by Waleed Bin Ghaffar, Muhammad Faisal Khan, Moeed Bin Abdul Ghaffar, Muhammad Sohaib, Asma Rayani, Muhammad Mehmood Alam, Syed Talha Sibtain, Zahra Cheema, Asad Latif

“…Vaccinated individuals, characterized by advanced age and higher Charlson Comorbidity Index, exhibited more critical disease (89.1%; p value: 0.06), acute respiratory distress syndrome (96.9%; p value: 0.013) and elevated inflammatory markers. …”
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Transforming research recruitment: Leveraging EHR systems and patient portals by Megan Schwinne, Edward Woods, Barney Chan, Candace D. Speight, Vivian Corry, Neal W. Dickert, Gabriel R. Najarro

“…Interest was also greater among those with frequent healthcare interactions and lower comorbidity. In a large academic health system, portal-based recruitment offered a streamlined approach to research recruitment and patient engagement, with minor variations across patient characteristics warranting continued study.…”
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Palliative endoscopic treatment of malignant central airway obstruction by Mads Bøgh, Sebastian Heinonen, Dalia Gustaityté Larsen, Søren Gade, Sten Schytte, Ulrik Pedersen, Thomas Kjaergaard

“…Survival was associated with comorbidity, type of intervention, preoperative respiratory support and postoperative oncologic treatment. …”
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WDRIV-Net: a weighted ensemble transfer learning to improve automatic type stratification of lumbar intervertebral disc bulge, prolapse, and herniation by Ichiro Nakamoto, Hua Chen, Rui Wang, Yan Guo, Wei Chen, Jie Feng, Jianfeng Wu

“…., disc herniation, prolapse, or bulge) and comorbidity-type degeneration (e.g., simultaneous presence of two or more conditions), respectively. …”
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Influence of Hypertension on Neurocognitive Domains in Nondemented Parkinson’s Disease Patients by Jacob D. Jones, Charles Jacobson, Martina Murphy, Catherine Price, Michael S. Okun, Dawn Bowers

“…Objective. Health comorbidities, particularly cardiovascular risk factors, are well known to pose risks for cognitive decline in older adults. …”
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Patient engagement in radiation oncology: a large retrospective study of survey response dynamics by Bailey A. Loving, Hong Ye, Elizabeth Rutka, John M. Robertson

“…Older adults, and patients with head and neck or genitourinary cancers were significantly more likely to participate, while those with higher comorbidities, MHD, or other minority status were less engaged (p<0.001). …”
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Gout Flare Burden in the United States: A Multiyear Cross‐Sectional Survey Study by Jasvinder A. Singh, Amy Morlock, Robert Morlock

“…Characteristics of those who were less likely to report gout flares included being younger, being less educated, having a lower Charlson Comorbidity Index score, not being diagnosed with gout by their doctor, and not taking a urate‐lowering therapy. …”
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Patient Management in Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus by A. E. Bagriy, A. D. Zubov, M. V. Khomenko, E. S. Mikhailichenko, E. A. Pylaeva, N. A. Khaustova, E. V. Bryukhovetskaya

“…Macro- and microvascular complications in T2D comorbidity entail a higher overall mortality. A conjunction of lifestyle change and rational medication strategies to reach the target levels of glycosylated haemoglobin, low-density lipoprotein cholesterol, systolic and diastolic blood pressure is key in management of such patients. …”
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Female sex is associated with short-term mortality in coronary artery bypass grafting patients: A propensity-matched analysis by Mostafa Abbas, Thomas Morland, Rohit Sharma, Jeffrey Shuhaiber, H. Lester Kirchner, Yasser El-Manzalawy

“…Background: Females undergoing coronary artery bypass grafting (CABG) surgery have been reported to be at increased risk of postoperative mortality and comorbidity. Our main objective is to evaluate the impact of female sex on 30-day mortality after isolated CABG surgery. …”
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ACCREDIT: Validation of clinical score for progression of COVID-19 while hospitalized by Vinicius Lins Costa Ok Melo, Pedro Emmanuel Alvarenga Americano do Brasil, PhD

“…Predictors such as demographic, clinical, comorbidities, laboratory, and imaging data were collected at hospitalization. …”
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Assessing the Economic Burden and Health Care Utilizations of U.S. Veteran Patients with Schizophrenia by Lin Xie, M. Furaha Kariburyo, Juan Du, Yuexi Wang

“…A group of patients without schizophrenia of the same age, region, gender and index year were identified and matched by baseline Charlson Comorbidity Index (CCI) score, as the comparison group. …”
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Complications during chest tube drainage for iatrogenic pneumothorax by Birgitte Siem Joensen, Uffe Bodtger, Christian B. Laursen, Rob J Hallifax, Beenish Iqbal, Søren Helbo Skaarup

“…However, guidance on iatrogenic pneumothorax occurring in patients with impaired lung function, increased age, comorbidity and frailty is lacking, and the safety profile of ambulatory management is not known. …”
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Association between early ondansetron use and the risk of sepsis in intensive care unit patients: a secondary data of the Medical Information Mart for Intensive Care IV database by Xuan Liu, Qiuye Kou, Enhe Liu

“…Subgroup analysis revealed that the association between early ondansetron use and decreased risk of sepsis was significant in participants aged <65 years, men, not complicated with trauma, no surgery, systemic inflammatory response syndrome ≥2, Charlson Comorbidity Index ≥2, with ventilation use, without antibiotics use or without insulin use. …”
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