Burden of coeliac disease in Germany: real-world insights from a large retrospective health insurance claims database analysis by Bernd Bokemeyer, Leonarda Serdani-Neuhaus, Juliane Sünwoldt, Christina Dünweber, Svitlana Schnaidt, Detlef Schuppan

“…Controls (non-CeD patients) were matched in a ratio of 5:1 by age, Charlson Comorbidity Index, sex and region. HCRU (hospitalisations, outpatient visits, medication use, sick leaves) and healthcare costs (outpatient services, inpatient services, outpatient pharmaceuticals, sick leaves and aids and remedies) were compared between CeD patients and controls. …”
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Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure by Paweł Krzesiński, Agata Galas, Grzegorz Gielerak, Beata Uziębło-Życzkowska

“…Anaemia is a common comorbidity in patients with heart failure (HF) and is associated with more severe symptoms and increased mortality. …”
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Evaluation of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Covid-19 Patients Treated with Tocilizumab Due to Cytokine Storm by Serkan Yavuz, Cengiz Burnik, Mehmet Mermer, Faysal Duksal

“…Materials and Methods: In this retrospective, cross-sectional study conducted in between March and December 2020, adult patients with laboratory-confirmed COVID-19 were analyzed Results; The mean age of 519 patients included in the study was 61.6 ± 17.0 years, with male predominance (64.7%). 70.7% of patients had at least one type of comorbidity and the most common comorbid conditions were chronic obstructive pulmonary disease (45.9%) and asthma (28.7%). 399 patients who were given TCZ (group 1) and 120 patients who were not given TCZ (group 2) were evaluated. …”
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COVID-19 Vaccination-Related Concerns Amongst Healthcare Workers by Ammarah Saeed, Bushra Rabbani, Naseem Amin Dhedhi, Faisal Ahmed, Mehrunnisa Umar, Jameel Ahmed

“…Results: The mean age of the study participants was 38.28±11.73 years, the majority were females (n=110, 55.8%), married (n=132, 67.0%), doctors by profession (n=129, 65.5%), non-smoker (n=169, 85.8%) and had no comorbidity (n=155, 78.7%). Out of 197 participants, 66 (33.5%) respondents exhibited their concerns regarding the side effects and efficacy of COVID-19 vaccination. …”
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Efficacy and Safety of Sitagliptin for the Treatment of New-Onset Diabetes after Renal Transplantation by Brian P. Boerner, Clifford D. Miles, Vijay Shivaswamy

“…New-onset diabetes after transplantation (NODAT) is a common comorbidity after renal transplantation. Though metformin is the first-line agent for the treatment of type 2 diabetes, in renal transplant recipients, metformin is frequently avoided due to concerns about renal dysfunction and risk for lactic acidosis. …”
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Interleukin-22 Might Act as a Double-Edged Sword in Type 2 Diabetes and Coronary Artery Disease by Fangchen Gong, Jin Wu, Ping Zhou, Mengyao Zhang, Jingning Liu, Ying Liu, Xiang Lu, Zhengxia Liu

“…Here we investigated the serum levels of five Th17-related cytokines (IL-17, IL-22, MIP-3α, IL-9, and IL-27) in T2DM, CAD, and T2DM-CAD comorbidity patients. IL-22 was found to be elevated in all three conditions. …”
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Spondyloarthritis and Risk of Malignancy: A Narrative Review on a Still Controversial Issue by Ennio Giulio Favalli, Francesco Grossi, Alberto Batticciotto, Matteo Filippini, Simone Parisi, Ombretta Viapiana, Paolo Gisondi, Paolo Dapavo, Lorenzo Dagna, Filippo De Braud

“…Malignancy may be a major comorbidity in subjects with spondyloarthritis (SpA) as the result of multifactorial mechanisms, from disease pathogenesis to the iatrogenic effect of immunomodulating drugs. …”
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Retropharyngeal Abscess in Adults: Five Case Reports and Review of the Literature by A. Harkani, R. Hassani, T. Ziad, L. Aderdour, H. Nouri, Y. Rochdi, A. Raji

“…The diagnosis of retropharyngeal abscess can be difficult and one must seek a comorbidity; a tuberculosis aetiology must be considered in countries with a high prevalence. …”
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HIV Late Presenters in Asia: Management and Public Health Challenges by Chen Seong Wong, Lyu Wei, Yeon-Sook Kim

“…HIV late presenters generally have a higher disease burden and higher comorbidity such as opportunistic infections than those who are diagnosed earlier. …”
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Interaction of Glycemic Control and Statin Use on Diabetes-Tuberculosis Treatment Outcome: A Nested Case-Control Study by Xiangrui Meng, Huiqiu Zheng, Jian Du, Xuemei Wang, Yanling Wang, Jing Hu, Jing Zhao, Qianqian Du, Yulong Gao

“…This study aims to explore the interaction of glycemic control and statin use on the treatment outcomes of pulmonary tuberculosis-diabetes comorbidity (PTB-DM) patients. A nested case-control study was conducted in a tuberculosis patients’ cohort. …”
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Does the consumption of soya products affect cholesterol levels, blood pressure, or other cardiovascular health indicators? by Aleksandra Walendzik, Kinga Racisz, Joanna Duda, Jakub Kędzia, Alicja Obcowska, Paweł Racisz, Łukasz Sencerek

“…Soy can be a part of our daily, healthy diet, but its impact on all-cause mortality and CVD depends on many factors such as people's age, comorbidity, dietary context and type of consumed soy ( e.g. fermented or not fermented). …”
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Aortic Balloon Valvuloplasty Prior to Orthotopic Liver Transplantation: A Novel Approach to Aortic Stenosis and End-Stage Liver Disease by Edward Coverstone, Kevin Korenblat, Jeffrey S. Crippin, William C. Chapman, Andrew M. Kates, Alan Zajarias

“…All patients had been deemed to be inappropriate candidates for liver transplantation or aortic valve surgery due to their comorbidity. One patient died of complications from a perivalvular abscess. …”
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Meaning mindset theory: a transdiagnostic approach to mental health promotion and intervention for children by Laura Lynne Armstrong, Emmalyne Watt, Catherine Laura Potter, Brent L. Epperson

“…There is substantial overlap and comorbidity among various mental health concerns and the onset of one mental illness elevates the risk of others, underscoring the potential limitations of singular-focused mental health education or treatment. …”
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Migraine and restless legs syndrome – is there an association? by D. Bučaitė, J. Normantas, G. Žemgulytė

“… Migraine and restless legs syndrome are diseases that disturb the normal quality of human life. Moreover, comorbidity of these disorders determines even more difficult condition of the patients. …”
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The Heart of the Matter: Health Status of Aged Care Clients Receiving Home- and Community-Based Care by Deborah Yarmo-Roberts, Rosanne Laura Freak-Poli, Brad Cooper, Tim Noonan, Just Stolewinder, Christopher M. Reid

“…The data suggests that as a group there is a high degree of comorbidity, and depression, dementia and caregiver strain are highly prevalent. …”
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Assessment of the risk of rapid progression of chronic kidney disease by L.D. Denova, D.D. Ivanov

“…The purpose of the study was to assess the risk of rapid progression of CKD in patients with stage 1–3 CKD by determining urinary albumin (uAlb)/urinary uromodulin (uUmod) ratio and comparing the obtained results with eGFR and the Charlson Comorbidity Index (CCI) in these patients. ­Materials and methods. …”
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Predictors of hospitalization, death and incomplete/non-recovery from SARS-CoV-2 in an ambulatory global population by Sarah L. Pett

“…Older age, male sex, comorbidities, pregnancy, symptomatic disease were each independently associated with hospitalization or death; SARS-CoV-2 vaccination reduced this risk. …”
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Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD. by Ava C Wilson, Alison Rocco, Joe Chiles, Vinodh Srinivasasainagendra, Wassim Labaki, Deborah Meyers, Bertha Hidalgo, Marguerite R Irvin, Surya P Bhatt, Hemant Tiwari, Merry-Lynn McDonald

“…Gastroesophageal reflux disease (GERD) is a common comorbidity in COPD associated with worse pulmonary symptoms, reduced quality of life, and increased exacerbations and hospitalizations. …”
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The impact of polypharmacy on health outcomes in the aged: A retrospective cohort study. by Irene Boateng, Carlos Rodriguez Pascual, Paul Grassby, Zahid Asghar, Kinda Ibrahim

“…The risk increased with an increase in age, potentially inappropriate medicines and comorbidities.…”
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Characteristics of type 2 diabetes mellitus patients at Puskesmas Sanden: A cross sectional study by Sari Dina Fitria, Sukirto Novi Wijayanti, Arifin Zainul, Devi Noor Rahmawati Evita, Irmawan Rano, Yuniasih Dewi, Masduki Imam

“…Hypertension was the most common comorbidity (63.0%). Many patients experienced complications such as nephropathy diabetic (4.0%), ophtalmic disease (9.0%), neuropathy diabetic (13.0%) and vascular disease (17.0%). …”
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