A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation by Jyotirmoy Sarker, Pritha Das, Sabarni Sarker, Apurba Kumar Roy, A. Z. M. Ruhul Momen

“…Besides, age-, sex-, and comorbidity-associated variation in infection rate correlates with the expression rate of TMPRSS2 in those groups. …”
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NCK2 Is Significantly Associated with Opiates Addiction in African-Origin Men by Zhifa Liu, Xiaobo Guo, Yuan Jiang, Heping Zhang

“…Codependence analysis also identified a genome-wide significant association between NCK2 and comorbidity of substance dependence (P value = 3.65E−08) in African-origin men. …”
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Invasive Pneumococcal Disease: Still Lots to Learn and a Need for Standardized Data Collection Instruments by T. J. Marrie, G. J. Tyrrell, Sumit R. Majumdar, Dean T. Eurich

“…Almost all (87%) had a major comorbidity and 15% had functional limitations prior to admission. …”
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Hormonal Therapies for Acne: A Comprehensive Update for Dermatologists by Courtney A. Smith, Emily Gosnell, Turkan Banu Karatas, Chelsea Deitelzweig, Elizabeth M. B. Collins, Howa Yeung

“…Dermatologists should discuss contraceptive options and provide individualized shared decision-making with patients based on patient preferences, contraceptive needs, comorbidity profile, access, and cost. Spironolactone is an effective acne treatment with clinical trial data to support its use as a first-line acne treatment for women with acne. …”
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Gastroesophageal Reflux Disease and Coronary Heart Disease: Is There a “Mutual Burden” Syndrome? by O. P. Alekseeva, D. V. Pikulev

“…In recent years, more and more information has appeared indicating a non-accidental character of the comorbidity of both diseases. In addition to common risk factors, a number of pathophysiological mechanisms have been established that determine a pathogenetic relationship between CHD and GERD. …”
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Pathogenesis of Severe Clinical Pictures of Influenza A (H1 N1). Some answers and new doubts. by Alfredo Darío Espinosa Brito, Ángel Julio Romero Cabrera

“…Among those groups are the people between the ages of 10 and 60 years, seemingly healthy, pregnant and postpartum women, and obese and asthmatic patients, but until now a specific medical comorbidity has not been evidenced in the 40 to 50% of the fatal cases. …”
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Risk factors of urinary tract infection through demographic and laboratory markers among benign prostate hyperplasia patients: a single-center study by Muhammad Andriady Saidi Nasution, Betthy Meilina Br Aruan, Suandy Suandy, Adrian Joshua Velaro, Naufal Nandita Firsty

“…The present study found that there were statistically significant differences between the neutrophil lymphocyte and the platelet-lymphocyte ratios in the incidence of urinary tract infections among BPH populations (p<0.05), while other studies documented that risk factors such as monocyte-to-lymphocyte ratio, catheter use, comorbidity status, and renal functions (urea, creatinine, and GFR levels) did not show significant differences (p>0.05). …”
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Short- and Midterm Results between Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy for the Treatment of Morbid Obesity by Bandar Albeladi, Céline Bourbao-Tournois, Noel Huten

“…Both LRYGB and LSG are safe procedures that provide good results in weight loss and resolution of comorbidities at 18 months.…”
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Polypharmacy in Patients with Type 2 Diabetes and Arterial Hypertension Treated in a Provincial Hospital by José Ander Asenjo Alarcón

“…<br /><strong>Results</strong>: 72.3 % of patients were women, their mean age was 68.6 years, the consumption of 4 drugs was the average for the comorbidity of type 2 diabetes and arterial hypertension, followed by 3 drugs in arterial hypertension, which represented polypharmacy for both cases (30.2 and 23.8 %, respectively). …”
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Skin Abscess due to Serratia marcescens in an Immunocompetent Patient after Receiving a Tattoo by J. Diranzo García, J. Villodre Jiménez, V. Zarzuela Sánchez, L. Castillo Ruiperez, A. Bru Pomer

“…In this paper we present the case of a 32-year-old male with no comorbidity, who presented an abscess caused by S. marcescens in a area that was tattooed one month earlier. …”
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Dislocation after Posterior Stabilized Primary Total Knee Replacement: A Rare Complication in Four Cases by W. Spierenburg, E. L. A. R. Mutsaerts, J. J. A. M. van Raay

“…Some of these risk factors were encountered as well as other comorbidity factors. Such risk factors must be taken into consideration when deciding whether to perform a total knee arthroplasty. …”
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Growth Differentiation Factor 15 and Risk of Death in Haemodialysis Patients by Christelle Calen, Seraina Von Moos, Pietro Cippà, Alexandre Mebazaa, Mattia Arrigo

“…Prevalence of most relevant comorbidities and the Charlson comorbidity index were similar across the two groups. …”
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Impacts of Coil Treatment on Anxiety and Depression in Emphysema by Tugce Toker Ugurlu, Erhan Ugurlu

“…Coil treatment as a current and novel treatment method for COPD-emphysema diagnosed patients with or without psychiatric comorbidity has a positive impact on anxiety and depressive symptoms.…”
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Clinical-surgical characterization of patients with acute pancreatitis. Cienfuegos, 2018- 2020 by Jorge Luis Estepa Ramos, Tahiluma Santana Pedraza, Jorge Luis Estepa Pérez, Yudis Acea Paredes, Roberto Pérez García

“…<br /><strong>Results:</strong> male patients aged 60 years old and over predominated; alcohol consumption and comorbidity not associated with acute pancreatitis, abdominal pain and vomiting were the most observed clinical variables. …”
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Impact of type 2 diabetes mellitus on results in the animal naming test in patients with and without liver cirrhosis. by Eva Maria Schleicher, Julia Tuchscher, Matthias Weber, Peter Robert Galle, Marcus-Alexander Wörns, Simon Johannes Gairing, Christian Labenz

“…<h4>Introduction and objectives</h4>Diabetes mellitus is a common comorbidity in patients with cirrhosis and is associated with the development of hepatic encephalopathy (HE) and cognitive dysfunction. …”
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Database Analysis of Eplerenone Use in Japanese Hypertensive Patients in Clinical Practice by Shoko Takahashi, Yoichi Ii, Yuji Yamamoto, Aya Ikeda, Yoko Fujimoto

“…The most frequent initial daily dose of eplerenone was 50 mg/day followed by 25 mg/day irrespective of the presence of a comorbidity. MRA use was as low as 2%, but its use was more frequent in patients with comorbidities compared to that of other antihypertensives. …”
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Health status correlates of malnutrition diagnosed based on the GLIM criteria in older Polish adults-Results of the PolSenior 2 study. by Aleksandra Kaluźniak-Szymanowska, Ewa Deskur-Śmielecka, Roma Krzymińska-Siemaszko, Arkadiusz Styszyński, Sławomir Tobis, Marta Lewandowicz, Jerzy Chudek, Tomasz Kostka, Małgorzata Mossakowska, Karolina Piotrowicz, Hanna Kujawska-Danecka, Katarzyna Wieczorowska-Tobis

“…In turn, nutritional deficiencies may enhance catabolic processes, leading to accelerated aging and comorbidity, thus creating a vicious cycle. Our study aimed to assess the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to determine the health correlates of malnutrition in a representative sample of community-dwelling older adults.…”
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Changing Landscape of Haemophilus influenzae Meningitis and Implication on Public Health by John Allonce, Mohammed Ahsan, Angelina Browne, Rebecca Witherell, Mark Rasnake

“…Diabetes was identified as a comorbidity. The patient’s condition improved after 14 days of antibiotics and dexamethasone. …”
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Effect of Preexisting Asthma on the Risk of ICU Admission, Intubation, and Death from COVID-19: A Systematic Review and Meta-Analysis by Abhinav Bhattarai, Garima Dhakal, Sangam Shah, Aastha Subedi, Sanjit Kumar Sah, Shyam Kumar Mishra

“…The Centers for Disease Control and Prevention (CDC) identifies asthma as a comorbidity in COVID-19 that increases the risk of severity and death. …”
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Percutaneous cholecystostomy for delayed laparoscopic cholecystectomy in patients with acute cholecystitis: analysis of a single-centre experience and literature review by Erdinc Kamer, Fevzi Cengiz, Volkan Cakir, Omur Balli, Turan Acar, Mustafa Peskersoy, Mehmet Haciyanli

“…The groups were statistically compared regarding their demographic, comorbidity, hospital stay, conservation, and complication rates. …”
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