Depression and Temporal Lobe Epilepsy: Expression Pattern of Calbindin Immunoreactivity in Hippocampal Dentate Gyrus of Patients Who Underwent Epilepsy Surgery with and without Comorbid Depression by Luciana D’Alessio, Hector Konopka, Patricia Solís, Laura Scévola, Mónica Fernandez Lima, Claudio Nuñez, Eduardo Seoane, Silvia Oddo, Silvia Kochen

“…The aim of this study was to determine the CB immunoreactivity in hippocampal dentate gyrus of patients who underwent epilepsy surgery for drug-resistant TLE with and without comorbid depression and/or memory deficits. Methods. …”
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Insufficient Evidence to Recommend Shu Mian Capsule in Managing Depression With or Without Comorbid Insomnia: A Systematic Review With Meta-Analysis and Trial Sequential Analysis by Zhao FY, Xu P, Kennedy GA, Jin X, Wang YM, Zhang WJ, Yue LP, Ho YS, Fu QQ, Conduit R

“…For depressed patients with comorbid insomnia, adding SMC to standard care demonstrates augmented efficacy and improved safety, though the supporting evidence is methodologically limited. …”
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Combine and Conquer: With Type 2 Diabetes Polypharmacy Is Essential Not Only to Achieve Glycemic Control but Also to Treat the Comorbidities and Stabilize or Slow the Advancement of Diabetic Nephropathy by David S. H. Bell

“…A combination of three or more medications usually at doses which are less than those utilized for monotherapy is efficacious not only in the therapy of hyperglycemia but also in the therapy of the comorbidities of hypertension and hyperlipidemia. In addition, multiple medications are now accepted as being necessary to reduce albuminuria and decelerate the decline in renal function in the patient with diabetic nephropathy.…”
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Features of language disorders in a person in advanced old age without known comorbid neurological or dementia diseases after undergoing a nervous breakdown by Renata Cuprych, Dominika A. Jaskólska, Ewa Boksa, Michał Robak, Izabella Leśniczuk

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Clinical outcomes and anti-inflammatory mechanisms predict maximum heart rate improvement after physical activity training in individuals with psychiatric disorders and comorbid obesity. by Pau Soldevila-Matías, Joan Vicent Sánchez-Ortí, Patricia Correa-Ghisays, Vicent Balanzá-Martínez, Gabriel Selva-Vera, Roberto Sanchis-Sanchis, Néstor Iglesias-García, Manuel Monfort-Pañego, Pilar Tomás-Martínez, Víctor M Victor, Benedicto Crespo-Facorro, Constanza San Martin Valenzuela, José Antonio Climent-Sánchez, Rosana Corral-Márquez, Inmaculada Fuentes-Durá, Rafael Tabarés-Seisdedos

“…<h4>Methods</h4>Patients with major depressive disorder, bipolar disorder and, schizophrenia and with comorbid obesity (n = 29) were assigned to a 12-week structured physical exercise program. …”
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Prevalence and determinants of overweight/obesity, elevated blood pressure, and their comorbidities among primary and secondary school students in Guizhou province: a cross-sectional survey by Zhuan WANG, Xiangdong DU, Xin LI, Xiaoqin ZHANG, Xiujuan LU, Xiying PENG

“…Chi-square test and multivariate logistic regression analysis were used to analyze the prevalence and determinants of the two disorders and their comorbidity. ResultsAmong the 182 616 students effectively surveyed, the prevalence of overweight/obesity was 23.0%, the detection rate of elevated blood pressure was 13.9%, and the comorbidity of both conditions was 4.4%. …”
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Maternal Hepatitis B Infection Burden, Comorbidity and Pregnancy Outcome in a Low-Income Population on the Myanmar-Thailand Border: A Retrospective Cohort Study by Marieke Bierhoff, Chaisiri Angkurawaranon, Aung Myat Min, Mary Ellen Gilder, Nay Win Tun, Arunrot Keereevijitt, Aye Kyi Win, Elsi Win, Verena Ilona Carrara, Tobias Brummaier, Cindy S. Chu, Laurence Thielemans, Kanlaya Sriprawat, Borimas Hanboonkunupakarn, Marcus Rijken, François Nosten, Michele van Vugt, Rose McGready

“…No significant associations were observed between pregnancy comorbidities or adverse pregnancy outcomes and HBV status. …”
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Clinicopathological characteristics of placental chorioangioma: A clinicopathological study of 30 cases by Yuanyin Zheng, Xiaobin Liu, Yingyu Mao, Maohua Lin

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Clinical spectrum of disease and outcomes in children with Omicron SARS-COV-2 infection in Cape Town, South Africa by C. Bekker, I. Dewandel, A. Redfern, C. McKenzie, J. Lishman, L. M. Verhagen, M. Claassen, S. Wilson, R. Dunbar, C. Bosch, G. van Zyl, W. Preiser, P. Goussard, H. Rabie, M. M. van der Zalm

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Psychiatric disorders in children and adolescents with temporal lobe epilepsy: A narrative review by Pietro Cappelletto, Claudia Accolla, Martina Preti, Tiziana Pisano, Carmen Barba, Renzo Guerrini

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Editorial: Obesity and cancer: the possible molecular links by Biswarup Basu, Debanjan Chakroborty, Debanjan Chakroborty, Debanjan Chakroborty, Chandrani Sarkar, Chandrani Sarkar, Chandrani Sarkar

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Analysis of Risk Factors for Death of Covid-19 Patients at Undata Hospital Palu by Nur Afni, Sri Rahayu

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Clinico-demographic factors affecting mortality in COVID-19 patients at a health care facility, Western Uttar Pradesh by Swati Singh, Anupam Sisodia, Meghna Athwani

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Hospitalizations with post-traumatic stress disorder in France between 2013 and 2022: a nationwide retrospective study by Alice Demesmaeker, Florian Dufrenois, Chloé Saint-Dizier, Guillaume Vaiva, Antoine Lamer, Mathilde Horn, Fabien D’Hondt

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Multimorbidity in adult patients diagnosed with atopic dermatitis by Szymon Mućka, Martyna Miodonska, Magdalena Mróz Dybowska, Anna Zyźlik, Alicja Grzanka, Robert Pawłowicz, Andrzej Bożek

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Oral Health and Noncommunicable Diseases (NCDs)

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Lumbar Spinal Stenosis Has a Negative Impact on Quality of Life Compared with Other Comorbidities: An Epidemiological Cross-Sectional Study of 1862 Community-Dwelling Individuals by Koji Otani, Shinichi Kikuchi, Shoji Yabuki, Tamaki Igarashi, Takuya Nikaido, Kazuyuki Watanabe, Shinichi Konno

“…In addition, the presence of comorbid conditions that affect QoL, such as osteoarthritis of the knee and hip, cardiovascular disease, cerebrovascular disease, or respiratory disease, was also analyzed. …”
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The effects of educational status and comorbidity on routine assessment of patient index data 3 and its correlation with disease activity score 28 and clinical disease activity index by Kubilay Sahin, Cem Ozisler, Nesibe Karahan Yesil, Fulya Dortbas, Ahmet Omma, Zeynep Ozbalkan Aslar, Yasar Karaaslan

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The incidence and influencing factors of recent suicide attempts in major depressive disorder patients comorbid with moderate-to-severe anxiety: a large-scale cross-sectional study by Lina Ren, Yeqing Dong, Xiaojing Zhou, Chuhao Zhang, Jiajia Gao, Lulu Li, Xiao Zhang, Min Zeng, Guoshuai Luo, Xiangyang Zhang

“…However, there is a lack of research that distinguishes the severity of comorbid anxiety disorders in MDD, and insufficient evidence exists regarding the prevalence of MDD patients with comorbid moderate-to-severe anxiety in the Chinese population. …”
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Pioglitazone Metformin Complex Improves Polycystic Ovary Syndrome Comorbid Psychological Distress via Inhibiting NLRP3 Inflammasome Activation: A Prospective Clinical Study by Qing-jun Guo, Jing Shan, Yi-feng Xu, Yan-yan Hu, Cui-lan Huo, Jing-yun Song, Chao-qun Wang, Hui Zhou, Chao-qin Yu, Qin Huang

“…This study aimed at investigating the therapeutic effect and mechanism of pioglitazone metformin complex preparation (PM) in polycystic ovary syndrome (PCOS) comorbid psychological distress. Methods. Seventy-five patients with PCOS comorbid psychological distress were randomly allocated into the PM, metformin, and placebo groups. …”
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