Zolpidem: Efficacy and Side Effects for Insomnia by Amber N. Edinoff, Natalie Wu, Yahya T. Ghaffar, Rosemary Prejean, Rachel Gremillion, Mark Cogburn, Azem A. Chami, Adam M. Kaye, Alan D. Kaye

“…Suicide attempts and completion have been successfully linked with zolpidem use (OR 2.08; 95% CI 1.83-2.63) in patients regardless of the presence of comorbid psychiatric illness. There have been multiple cases reported of seizures following the withdrawal of zolpidem. …”
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Association of depression in multiple sclerosis with fatigue, sleep disturbances, disability, and health-related quality of life: Outcomes of a cross-sectional study by E. Aparicio-Castro, A. Candeliere-Merlicco, C.M. Santa, R. Villaverde-González

“…Conclusion: This study underscores the prevalence and impact of depression in MS, emphasizing the importance of routine screening and active management of psychiatric comorbidities in individuals with MS. These findings contribute valuable insights into the complex interplay between mental health, disease variables, and QoL in MS. …”
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Exploration of rituximab treatment strategies for membranous nephropathy adapted to the Chinese healthcare environment by Xiaolong Wang, Xueying Cao, Jie Wu, Shuang Liang, Jian Yang, Hong Wang

“…Multivariate Cox regression analysis revealed that the standard RTX treatment regimen was associated with a better remission rate, whereas comorbid diabetes reduced the remission rate. Older age and higher white blood cell counts may lead to a higher relapse rate. …”
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Hybrid versus vaccine immunity of mRNA-1273 among people living with HIV in East and Southern Africa: a prospective cohort analysis from the multicentre CoVPN 3008 (Ubuntu) studyRe... by Nigel Garrett, Asa Tapley, Aaron Hudson, Sufia Dadabhai, Bo Zhang, Nyaradzo M. Mgodi, Jessica Andriesen, Azwidihwi Takalani, Leigh H. Fisher, Jia Jin Kee, Craig A. Magaret, Manuel Villaran, John Hural, Erica Andersen-Nissen, Guido Ferarri, Maurine D. Miner, Bert Le Roux, Eduan Wilkinson, Richard Lessells, Tulio de Oliveira, Jackline Odhiambo, Parth Shah, Laura Polakowski, Margaret Yacovone, Taraz Samandari, Zvavahera Chirenje, Peter James Elyanu, Joseph Makhema, Ethel Kamuti, Harriet Nuwagaba-Biribonwoha, Sharlaa Badal-Faesen, William Brumskine, Soritha Coetzer, Rodney Dawson, Sinead Delany-Moretlwe, Andreas Henri Diacon, Samantha Fry, Katherine Margaret Gill, Zaheer Ahmed Ebrahim Hoosain, Mina C. Hosseinipour, Mubiana Inambao, Craig Innes, Steve Innes, Dishiki Kalonji, Margaret Kasaro, Priya Kassim, Noel Kayange, William Kilembe, Fatima Laher, Moelo Malahleha, Vongane Louisa Maluleke, Grace Mboya, Kirsten McHarry, Essack Mitha, Kathryn Mngadi, Pamela Mda, Tumelo Moloantoa, Cissy Kityo Mutuluuza, Nivashnee Naicker, Vimla Naicker, Anusha Nana, Annet Nanvubya, Maphoshane Nchabeleng, Walter Otieno, Elsje Louise Potgieter, Disebo Potloane, Zelda Punt, Jamil Said, Yashna Singh, Mohammed Siddique Tayob, Yacoob Vahed, Deo Ogema Wabwire, M. Juliana McElrath, James G. Kublin, Linda-Gail Bekker, Peter B. Gilbert, Lawrence Corey, Glenda E. Gray, Yunda Huang, Philip Kotze, Sharlaa Badal-Faesen, Kagisho Baepanye, Veronique Bailey, Katekani Baloyi-Oseh, Mumtaz Booley, Johannes Louis Botha, Yolande Brown, Valerie Brown, Lisa Bunts, Soritha Coetzer, Myron Cohen, Shirley Collie, Rodney Dawson, Pallabi Deb, Hana El Sahly, Jill El-Khorazaty, Andries Engelbrecht, Marianne Gildea, Dhevium Govender, Jen Hanke, Jayla Harris, Simone Hendricks, Nick Hopkinson, Haley Howell, Nzeera Ketter, Kentse Khuto, Faatima Laher Omar, Leolin Katsidzira, Kim Linton, James Ludwig, Bongile Mabilane, Matshidiso Malefo, Ndiitwani Mamushiana, Daciana Margineantu, Jeanine May, Fatima Mayat, Cindy Molitor, Yeshnee Naidoo, Michelle Nebergall, Alan Nguyen, Sarah Nikles, Bianca Noronha, Melissa Peda, Tamara Phiri, Shanthie Pillay, Sureshnee Pillay, Lori Proulx-Burns, Laurie Rinn, Lisa Sanders, Carrie Sopher, Smitha Sripathy, Michael Stirewalt, Houriiyah Tegally, Sara Thiebaud, Alicia Toledano, Stephanie Van Wyk, Shamaya Whitby, Stephany Wilcox, Eduan Wilkinson, Haven Wilvich, Charles Wiysonge, Nelisiwe Xaba, Ntokozo Xulu

“…Methods: Previously unvaccinated adults with HIV and/or other comorbidities associated with severe COVID-19 received either one (hybrid immunity) or two (vaccine immunity) 100-mcg doses of ancestral strain mRNA-1273 in the first month, depending on baseline evidence of prior SARS-CoV-2 infection. …”
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Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity by Pereira AP, Janela D, Areias AC, Molinos M, Tong X, Bento V, Yanamadala V, Cohen SP, Correia FD, Costa F

“…The rising prevalence of obesity calls for scalable solutions to address MSK conditions in this population, given their complex clinical profile and barriers to accessing care.Purpose: To evaluate the engagement and clinical outcomes of a fully remote digital care program in patients with MSK conditions, focusing on those with and without comorbid obesity.Patients and Methods: A post-hoc analysis of a prospective, longitudinal, single-arm observational home-based study conducted between August, 2023, and August, 2024. …”
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Resultados a corto y largo plazo tras trasplante cardíaco en pacientes con cardiopatías congénitas by Marta Molina, Elena Roselló, Manel Tauron, Juan F. Tabilo, Constanza Fernandez, Carla Gotsens, Exzequiel Pueblas, José Montiel, Sandra Casellas, Angela Irabien, Laura Corominas, Laura López, Sonia Mirabet, Antonino Ginel

“…Transplanted patients with congenital heart diseases were younger, had fewer comorbidities, and a higher number of previous interventions (P < .05). …”
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Características clínicas y tratamiento farmacológico de los pacientes con insuficiencia cardíaca en una cohorte de atención primaria by Maria Giner-Sorian, Ramon Monfà, Roser Vives, Silvia Fernández-García, Antoni Vallano, Rosa Morros

“…Main measurements: Sociodemographic and anthropometric variables, left ventricular ejection fraction (LVEF), New York Heart Association (NYHA), laboratory data, comorbidities, exposure to drugs for HF and other pathologies. …”
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Appropriateness of urine culture requests in primary care in Spain: A cross-sectional descriptive study by Silvia Fernández-García, Ramon Monfà, Cristina Miranda Jiménez, Maria Giner-Soriano, Frederic Gómez, Ana Moragas

“…Main measures: The collected variables included sociodemographic data, urinary tract infection (UTI) symptoms at the time of the urine culture request, comorbidities, reason for the request (including diagnosis), type of urine culture, therapeutic approach before and after receiving the result, and the urine culture result. …”
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Unexpected identification of peak systolic velocity in the radial artery as a risk factor for functional primary patency of radiocephalic fistulas by Rui Cong, Songxiu Li, Shasha Shi

“…Preoperative ultrasound parameters, demographic characteristics, serum indicators and comorbidities were recorded. The functionality of radiocephalic fistulas would be assessed every 6 months until March 2023, following their unassisted maturation, unless AVF dysfunction, kidney transplantation, mortality or loss to follow-up occurred. …”
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Unexpected identification of peak systolic velocity in the radial artery as a risk factor for functional primary patency of radiocephalic fistulas by Rui Cong, Songxiu Li, Shasha Shi

“…Preoperative ultrasound parameters, demographic characteristics, serum indicators and comorbidities were recorded. The functionality of radiocephalic fistulas would be assessed every 6 months until March 2023, following their unassisted maturation, unless AVF dysfunction, kidney transplantation, mortality or loss to follow-up occurred. …”
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Recommendations for the use of natriuretic peptides for early diagnosis of heart disease in patients with diabetes: A consensus report by SPEDM, SPC, NEDM-SPMI and APMGF by João Sérgio Neves, Rui Baptista, Estêvão Azevedo de Pape, Manuel Rodrigues Pereira, Rita Paulos, Jonathan Pinheiro dos Santos, Cristina Gavina, João Jácome de Castro

“…Accordingly, this consensus advises the use of NT-proBNP analysis for all patients with diabetes aged 50 years and older, or under 50 if they have risk factors and/or comorbidities. Adjusted rule-out and rule-in values for age, sex and risk factors are provided. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…Individuals of advanced age or with severe life-limiting comorbidities separate from their end-stage organ failure are less likely to survive after receiving an allograft or a research xenograft. …”
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