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1301
Metabolically activated and highly polyfunctional intratumoral VISTA+ regulatory B cells are associated with tumor recurrence in early-stage NSCLC
Published 2025-01-01“…VISTA+ Bregs displayed high metabolic demand and were able to produce different cytokines, including interleukin (IL)-10, transforming growth factor (TGF)-β, IL-6, tumor necrosis factor (TNF), and granulocyte–macrophage colony-stimulating factor (GM-CSF). Spatial analysis showed colocalization of B cells with CD4+/CD8+ T lymphocytes in TME. …”
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1302
Creation of body color mutants by CRISPR/Cas9 gene editing in largemouth bass, Micropterus salmoides
Published 2025-03-01“…The fertilized eggs were obtained through hormonal induction (5 μg/kg LHRH-A3, 600 IU/kg hCG and 2 mg/kg DOM) and artificial insemination, and the tyrb (tyrosinase b) or csf1ra (colony-stimulating factor 1 receptor a) gRNA and Cas9 mRNA were microinjected into the fertilized eggs at the one-cell stage for targeted gene editing. …”
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1303
Preclinical pharmaco-toxicological screening of biomimetic melanin-like nanoparticles as a potential therapeutic strategy for cutaneous melanoma
Published 2025-02-01“…The cytotoxic, anti-migratory, anti-clonogenic, pro-oxidant and pro-apoptotic properties of MEL-NPs were investigated in vitro by applying the MTT viability test, bright-field and immunofluorescence microscopy, DCFDA/H2DCFDA test, scratch assay, colony formation assay, and RT-qPCR. The irritant and anti-angiogenic effects were assessed in ovo on the vascularized chorioallantoic membrane (CAM).ResultsThe as-made MEL-NPs presented a spherical morphology, an average size of 85.61 nm, a broad UV-VIS absorption spectrum, and a strong antioxidant activity. …”
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1304
ENO1 promotes PDAC progression by inhibiting CD8+ T cell infiltration through upregulating PD-L1 expression via HIF-1α signaling
Published 2025-02-01“…In vitro, Eno1 knockdown resulted in reduced PDAC cell proliferation and colony formation, along with enhanced apoptosis in PDAC cells. …”
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1305
Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium
Published 2025-01-01“…As a result, the biofilm formation ability of 269ΔSTM0343 was enhanced by 21.54%, accompanied by a more pronounced red, dry, and rough colony morphology. 269ΔSTM0343 also showed a 19.03% decrease in motility due to the downregulation of flhD expression. …”
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1306
Alimentation et gestion de l’eau sur la colline de Fourvière à Lyon : les aménagements hydrauliques, la ville et ses monuments
Published 2023-12-01“…On Fourvière hill, which reaches a maximum altitude of about 298 m NGF, the public buildings, thermal baths, fountains, reservoirs as well as the houses and private amenities were supplied with water by the four Lyon aqueducts.The constraints caused by the topography of the hill on which the Roman colony was established made it difficult to supply the districts located in the highest part of the hill, in particular those located above 270 m. …”
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1307
The dynamics of African indigenous knowledge systems : a sustainable alternative for livelihoods in southern Africa /
Published 2022Table of Contents: “…Introduction: The dynamics of indigenous knowledges and sustainable livelihoods in Africa / Edward Shizha and Christopher Ndlovu -- Mainstreaming and investing in indigenous knowledge epistemologies for sustainable livelihoods / Edward Shizha -- Buttressing sustainable security systems through African indigenous epistemologies / Shepherd Ndondo and Christopher Ndlovu -- Harnessing indigenous conflict resolution processes in building sustainable communities / Mandlenkosi Ndlovu -- Participation of diasporas in building sustainable communities in Zimbabwe: Implementation of Ubuntu philosophy / Roland Moyo, Christopher Ndlovu and Edward Shizha -- The role of indigenous knowledge systems in sustainable adaptation to climate change / Tinashe Pikirai -- Understanding climate change adaptation for increased productivity and sustainability in Southern African communities: A review / Keith Phiri -- Implementing indigenous knowledge systems for sustainable learning in African primary schools / Emily Mangwaya and Ezron Mangwaya -- Integration of indigenous mathematical knowledge into the mathematics education for sustainable learning / Nhlanhla Mkwelie, Ntandoyenkosi Satamwe and Edward Shizha -- Embedding sustainability and Ubuntu philosophy in the learning of learners with disruptive behaviours / Mlungisi Moyo -- Language of instruction imbroglio in the post-colonial school curriculum (Zimbabwe Curriculum Framework, 2015-2020): The obstacle to sustainable learning / Otildah S. …”
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1308
Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.)
Published 2023-12-01“…While it is true that the decision to install chambered cisterns to regulate the slope of the hillside may have served to enlarge the building spaces, it is equally plausible that their purpose was also to provide the city wall defences with water reserves to supply the militia in case of siege or fire, in accordance with a common practice in ancient urban design.The military value of some of these cisterns, however, lost its significance after the establishment of the colony, as did walled fortifications. For this reason, the growing tendency to build sumptuous dwellings, with an enviable viewpoint overlooking the Sarno plain below, led to buildings being extended above and beyond the defensive walls, even reusing structural parts that were no longer considered necessary.In the same way, many of the cisterns behind them lost their function, being converted into rooms in the house or used as stairways or corridors.The large basins seem to have retained their function until the advent of the aqueduct system, introduced in Pompeii in the Augustan age. …”
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1309
The African Nationalist Idea of Africa
Published 2022-11-01“… This paper probes the impact of colonial designs in the fabrication of native subjectivities, which eventuated in toxic political identities that would later undermine the post-colonial nationalist project. …”
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1310
Decolonising biblical hermeneutics in the (South) African context
Published 2016-12-01“…From our own social location (Africa), biblical hermeneutics has to deal with the dynamics of coloniality. Africa, especially South Africa as a social location, is still burdened by coloniality. …”
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1311
Thabo Mbeki’s Decolonial Idea of an African in the African Renaissance
Published 2022-11-01“…Through colonialism, settlers became local in Africa and Africans became aliens in their own native territories. …”
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1312
Ancient Piracy Activities of Garp Ocakları in Mediterranean World as an International Problem in XVIII Century
Published 2015-12-01“…The most significant military force of the Western Colonies was the fleets. Those colonies, having a significant nautical power within the Mediterranean basin, made a great contribution to the naval forces of Ottoman state after they were captured. …”
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1313
Further Reflecting on the Six-Year Primary Project of the Institute of Education, University of Ife: The Key Players
Published 2021-12-01“… African linguistic complexity is often defined in terms of its multilingualism and a complicated colonial sociolinguistic heritage. Tis colonial heritage is seen in the prevalence of European languages, especially English and French, in the lingual Franca of sub-Saharan states. …”
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1314
Biblical discourses and the subjugation of Africa: A Decolonial-Foucauldian perspective
Published 2023-11-01“…The de-colonial motif was used to problematise these discourses. …”
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1315
Impact of Comb Cell Diameter on Nectar Evaporation Efficiency in Honey Bees
Published 2025-01-01“…Additionally, EHB colonies were more effective than WHB colonies in converting sucrose into fructose and glucose. …”
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1316
Polyphonies coloniales
Published 2021-12-01“…As an integral part of the post-colonial national and heritage narrative of Mauritius, the Mauritian Sega is also part of another history, which is to be found in colonial narrative, but rather in an oral literature, in which the ability of performers of Sega to destabilize an essentialist conception of Mauritian creolity can still be heard. …”
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1317
Chief Isaac Oluwole Delano: A Legend and His Legacy
Published 2021-12-01“…The head of a lazy person is not comparable to the nail of the strong; shame follows the pride of the lazy.2 Chief Isaac Delano discovered his intellectual mission during the colonial moment. The nature of the colonial state influenced his writings. …”
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1318
THE SIGNIFICANCE OF FANON’S POLITICAL THEORY TO PAN AFRICANISM
Published 2023-06-01“…This according to him was a ‘’divide and rule system’’ by the colonialists, to penetrate deeply into their colonies’ administrative structures. …”
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1319
Les Jeunes Tunisiens, une contre-expérience de la minoration ? Politisation des langues dans la presse francophone en Tunisie coloniale (1907-1912)
Published 2022-06-01“…Les Jeunes Tunisiens (the Young Tunisians) laid the groundwork for a mobilisation of the political landscape of colonial Tunisia at the beginning of the 20th century. …”
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1320
Beyond exceptionalism
Published 2025-01-01“…We highlight a shared history of colonial complicity and ongoing coloniality towards Indigenous and minoritised groups. …”
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