ONC213: a novel strategy to resensitize resistant AML cells to venetoclax through induction of mitochondrial stress by Jenna L. Carter, Yongwei Su, Eman T. Al-Antary, Jianlei Zhao, Xinan Qiao, Guan Wang, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Steven A. Buck, Maik Hüttemann, Joshua E. Allen, Varun V. Prabhu, Jay Yang, Jeffrey W. Taub, Yubin Ge

“…The combination significantly reduced colony formation capacity of primary AML progenitors compared to the control and either treatment alone. …”
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LURAP1L-AS1 long noncoding RNA promotes breast cancer progression and associates with poor prognosis by Radhakrishnan Vishnubalaji, Dania Awata, Nehad M. Alajez

“…Survival analysis of TNBC patients demonstrated a significant association between elevated LURAP1L-AS1 expression and poor clinical outcomes.LURAP1L-AS1 knockdown significantly impaired colony formation and organoid growth of TNBC models, associated with increased apoptosis thus highlighting its role in promoting tumorigenicity. …”
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UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer by Yunjie Tian, Ruoyu Dong, Yingxia Guan, Ying Wang, Wei Zhao, Jun Zhang, Shan Kang

“…Finally, the effects of key markers on HGSOC cells were evaluated via Cell Counting Kit-8 (CCK-8), Transwell, colony formation, wound healing, immunofluorescence and in vivo tumor growth assays. …”
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Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors by Romain Pacaud, Scott Thomas, Sibapriya Chaudhuri, Ann Lazar, Luika A. Timmerman, Pamela N. Munster

“…We compared therapeutic response features such as RAD51 focus formation, cell cycle fraction alterations, DNA damage accumulation, colony formation, and cell death of these and other cell lines with and without intrinsic BRCA1/2 mutations. …”
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Exploring the inhibitory effect and mechanism of isorhamnetin therapy on oral squamous cell carcinoma based on network pharmacology and molecular docking by YU Fangfang, ZHOU Jingjing, YANG Jie, QU Huijuan, HUI Guangyan

“…Iso and core targets were also analyzed through molecular docking and visualization. Colony formation assay and Transwell assay were used to identify the effect of Iso on the proliferation and invasion of Cal-27 cells. …”
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Quelques observations sur l’alimentation des bonobos en semi-liberté au sanctuaire « Tasok » de Kinshasa by Paul N ’ Lemvo Budiongo

“…Dix-neuf bonobos d’âges variés en semi-liberté au Sanctuaire de Bonobos de Kinshasa et nourris aux fruits, légumes et canne à sucre dont la quantité totale préparée pour toute la colonie variait entre 73,80 et 127,84 kg par jour. …”
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Co-design in healthcare with and for First Nations Peoples of the land now known as Australia: a narrative review by James Gerrard, Shirley Godwin, Kim Whiteley, James Charles, Sean Sadler, Vivienne Chuter

“…There are concerns that inauthenticity in co-design will further perpetuate and ingrain harms inbuilt to colonial systems. Co-design is a tool that inherently must truly reposition power to First Nations Peoples, engendering both respect and ownership. …”
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Comprehensive investigation of matrix metalloproteinases in skin cutaneous melanoma: diagnostic, prognostic, and therapeutic insights by Lingxia Wu, Chenxiaoxiao Liu, Weicai Hu

“…Functional assays, including cell proliferation, colony formation, and wound healing, were conducted post-MMP7 knockdown using siRNA in A375 cells. …”
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TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…Immunofluorescence staining and immunoprecipitation analyses were performed to investigate the binding relationship between TWIST1 and HK2. Colony formation and Transwell assays were utilized to evaluate the effects of TWIST1 on cell proliferation, migration, and invasion. …”
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Potential role of P4HB in the tumor microenvironment and its clinical prognostic value: a comprehensive pan-cancer analysis and experimental validation with a focus on KIRC by Linxue Zhang, Yu-wei Li, Tianyi Xie, Ke Sun, Xiang Huang, Wei Xiong, Rui-ji Liu

“…Finally, the oncogenic role of P4HB in RCC cells was validated using colony formation and wound healing assays. Results RNA and protein levels of P4HB were extensively up-regulated in pan-cancer. …”
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Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway by Xiaoping Yu, Xiaolong Song, Jiali Yan, Ziting Xiong, Lujie Zheng, Yan Luo, Fengcheng Deng, Yanfeng Zhu

“…Design: We utilized cell counting kit-8 (CCK-8) assays, colony formation assays, and scratch assays to evaluate the influence of Dp on the proliferation and migration of TNBC cells. …”
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La ruta del cacique Llampilanguen (1804): la reconstrucción geográfica de un camino. histórico by Walter Daniel Melo, Juan Francisco Jiménez, Sebastián Leandro Alioto

“…De este modo, las diversas herramientas y aplicaciones que contienen los SIG han ayudado a recuperar el trazado de antiguas vías de comunicación en regiones que, por estar fuera del control colonial, eran malamente conocidas por las autoridades de la burocracia imperial, y no han quedado consignadas en su cartografía. …”
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Réflexions sur la dichotomie entre néolocuteurs et locuteurs natifs/traditionnels dans le cadre de la revitalisation des langues minoritaires : vers un nouveau discours inclusif by Robert Neal Baxter

“…The phenomenon of newspeakerism is discussed within the context of minority languages in the light of the native/non-native speaker dichotomy. Tracing the colonial origins of the concept of the native speaker reveals how the divide is underpinned by an exclusivist narrative based on accident of birth, leading to a consensus within second language teaching for the need to overcome what is described as a racist ideology. …”
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Cerro San Antonio (L1): A Palimpsest of the South-Central Andean Past (ca. 1500 BC - AD 1950) in the Middle Locumba Valley, Tacna, Peru by Matthew J. Sitek

“…The site is a true palimpsest of the local past, comprising 28 archaeological sectors that show evidence of occupation and use beginning in the Formative period (ca. 1500 BC - AD 500), continuing through the historical colonial-republican periods (ca. AD 1550-1950) and on into today, with the most significant occupations dating to the Middle Horizon (ca. …”
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Pathogenicity of Entomopathogenic Fungi from Peanut Rhizosphere ( Arachis hypogaea Linnaeus) to Pod Borer Etiella zinckenella Treitschke (Lepidoptera: Pyralidae) by Reflinaldon Reflinaldon, Martinius Martinius

“…Furthermore, the purification was based on the shape and color of the fungus colonies. A total of 16 isolates obtained at the initial stage were selected by testing them against the fifth instar larvae Tenebrio molitor. …”
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Identifikasi Orchid Mycorrhiza Pada Akar Anggrek Dendrobium nobile by Metari Arsitalia

“…The method used was with a descriptive design on the identified orchids, samples in the form of Dendrobium nobile orchid roots, the media used was PDA media, transverse and longitudinal root cut types.  The way it works includes sample preparation, media preparation, fungal isolation, fungal colony purification,…”
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Les calebasses nka’a kügha : du contexte d’origine à la mise en exposition en Europe by Ninon Arbez-Gindre

“…These symbols of victory were the used for rituals and considered the dynasty’s regalia. During the colonial period, they became artefacts collected by Europeans, particularly missionaries. …”
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The immunoregulatory and allergy-associated cytokines in the aetiology of the otitis media with effusion by Marina G. Smirnova, John P. Birchall, Jeffrey P. Pearson

“…In this review we present cytokines identified in otitis media, immunoregulatory [interleukin (IL)-2, IL-10, transforming growth factor-β]) and allergy associated (IL-4, IL-5, granulocyte-macrophage colony-stimulating factor), as crucial molecular regulators, responsible for chronic inflammation in the middle ear and the chronic condition of OME.…”
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Des lieux pour un « non-lieu » : Le camp algérien Paul-Cazelles et Hocine Kahouadji, militant FLN by Susan Slyomovics

“…Despite decisions of “non-lieu” rendered by the French legal system, many Algerian FLN militants arrested in France were kept imprisoned serially in carceral sites and transferred from metropolitan prisons to Algeria’s colonial ones. Although French prison camps in Algeria varied, this essay concentrates on Camp Paul-Cazelles located in Ain Ousseras, 195 km south of Algiers. …”
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El discurso amoroso de Luz Acmé, alter ego de María Jesús Alvarado, y la búsqueda del marido ideal by Giovanna Pollarolo

“…In the first and only novel she published, Nuevas Cumbres (1923), María Jesús Alvarado recounts the founding of Ciudad Cumbre, a model colony of the ideal society that its creator, Luz Acmé, installed “en las selvas ubérrimas de Oriente” and in which is inhabited by 10,000 settlers. …”
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