Showing 101 - 120 results of 171 for search '"Cognitive deficit"', query time: 0.06s Refine Results
  1. 101

    Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine by Marta Vicente-Rodríguez, Rosalía Fernández-Calle, Esther Gramage, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón

    Published 2016-01-01
    “…Since striatal neuroinflammation induced by amphetamine-type stimulants correlates with the cognitive deficits induced by these drugs, we also tested the long-term effects of periadolescent amphetamine treatment (3 mg/kg i.p. daily for 10 days) in a memory task in MK−/− and WT mice. …”
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  2. 102

    FGF2 Attenuates Neural Cell Death via Suppressing Autophagy after Rat Mild Traumatic Brain Injury by Chonghui Tang, Yudong Shan, Yilan Hu, Zhanjian Fang, Yun Tong, Mengdan Chen, Xiaojie Wei, Xiaojun Fu, Xinlong Xu

    Published 2017-01-01
    “…Traumatic brain injury (TBI) can lead to physical and cognitive deficits, which are caused by the secondary injury process. …”
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  3. 103

    Possible influence of sex on the relationship between dual-task gait costs and cognitive decline in older adults. by Monica Christova, Shane Fresnoza, Christoph Palli, Wolfgang Staubmann, Bernhard Guggenberger

    Published 2025-01-01
    “…Previous research demonstrated that higher DTG costs correlate with increasing cognitive deficits and with age. The present study was conducted to explore whether the relationship between the DTG costs and cognitive abilities in older individuals is influenced by sex differences. …”
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  4. 104

    The development of a story recall test for distinguishing between Alzheimer’s disease and mild cognitive impairment in Thai cohort by Natinee Na Chiangmai, Peera Wongupparaj, Pattrawadee Makmee, Claudio Mulatti, Remo Job

    Published 2025-01-01
    “…Thus, delayed recall in the TSR has the potential to detect cognitive deficits in Thai older adults, especially when combined with other neuropsychological measures. …”
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  5. 105

    A systematic review of exposure to toxic elements and neurocognitive development in children by Tingyi Guo, Moslem Lari Najafi, Junmei Zhang

    Published 2025-02-01
    “…Exposure to potentially toxic elements (PTEs) has been implicated in neurodevelopmental disorders and cognitive deficits in children. However, the extent of this association and the underlying mechanisms remain poorly understood. …”
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  6. 106

    Identification of unmet palliative care needs of nursing home residents: A scoping review protocol. by Patrice Crowley, Mohamad M Saab, Nicola Cornally, Isabel Ronan, Sabin Tabirca, David Murphy

    Published 2024-01-01
    “…<h4>Introduction</h4>Nursing home residents often have life limiting illnesses in combination with multiple comorbidities, cognitive deficits, and frailty. Due to these complex characteristics, a high proportion of nursing home residents require palliative care. …”
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  7. 107

    Corticolimbic circuitry as a druggable target in schizophrenia spectrum disorders: a narrative review by Abigail Gee, Paola Dazzan, Anthony A. Grace, Gemma Modinos

    Published 2025-01-01
    “…Understanding how neural circuitry and molecular mechanisms within this corticolimbic system may contribute to the development of not only positive symptoms but also negative and cognitive deficits in SSD has been a recent focus of intense research, as the latter are not adequately treated by current antipsychotic medications and are more strongly associated with poorer functioning and long-term outcomes. …”
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  8. 108

    Lack of UBE3A-Mediated Regulation of Synaptic SK2 Channels Contributes to Learning and Memory Impairment in the Female Mouse Model of Angelman Syndrome by Jiandong Sun, Yan Liu, Xiaoning Hao, Michel Baudry, Xiaoning Bi

    Published 2022-01-01
    “…Angelman syndrome (AS) is a rare neurodevelopmental disorder characterized by severe developmental delay, motor impairment, language and cognition deficits, and often with increased seizure activity. …”
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  9. 109

    Learning Slope and Position Effects in Rey Auditory Verbal Learning Test: Diagnostic Value in Schizophrenia by M. Alfimova, V.V. Plakunova, V.E. Golimbet

    Published 2024-11-01
    “… <p>Impairments of verbal episodic memory are a central component of cognitive deficits in schizophrenia, and their investigation is important for solving diagnostic, expert and rehabilitation tasks. …”
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  10. 110

    Neuropsychiatric Symptoms in Clinically Defined Parkinson’s Disease: An Updated Review of Literature by Paloma Macías-García, Raúl Rashid-López, Álvaro J. Cruz-Gómez, Elena Lozano-Soto, Florencia Sanmartino, Raúl Espinosa-Rosso, Javier J. González-Rosa

    Published 2022-01-01
    “…Patients with more significant cognitive deficits and higher levels of NPS appeared to be of older age with a longer disease duration and to have more severe motor symptoms. …”
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  11. 111

    Effects of neurocognitive intervention in older adults. A systematic review by Elizabeth Jiménez Puig, Zoylen Fernández Fleites, Yunier Broche Pérez, Daniela Beatriz Vázquez Martínez

    Published 2021-10-01
    “…<strong>Background:</strong> The need for neurocognitive intervention in older adults, as well as the various positions regarding its benefits, justify the relevance of systematizing the dissimilar proposals for neurocognitive intervention in people with and without cognitive deficits. Knowledge of the impact of these interventions on the cognitive health of these people is vitally important. …”
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  12. 112

    Efficacy of home based computerized adaptive cognitive training in patients with post stroke cognitive impairment: a randomized controlled trial by Amit Kumar Soni, Mohit Kumar, Saroj Kothari

    Published 2025-01-01
    “…These findings are specific to patients recovering from stroke-induced cognitive deficits and highlight the need for further research to generalize these results to other populations with vascular cognitive impairment.…”
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  13. 113

    Cognitive changes and quality of life in neurocysticercosis: a longitudinal study. by Mitchell T Wallin, E Javier Pretell, Javier A Bustos, Marianella Caballero, Mercedes Alfaro, Robert Kane, Jeffrey Wilken, Cynthia Sullivan, Timothy Fratto, Hector H Garcia

    Published 2012-01-01
    “…<h4>Conclusions/significance</h4>Newly diagnosed patients with NCC in this sample had mild cognitive deficits and more marked decreases in quality of life at baseline compared with controls. …”
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  14. 114

    Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis by Juan Hu, Qiao Li, Shiqiu Jiang, Yingying Deng, Lan Yang, Mengyu Du, Shuxuan He, Fuxing Xu, Chaoying Yan, Wei Gao, Yansong Li, Yaomin Zhu

    Published 2025-03-01
    “…Post-transplantation of platelet-derived mitochondria (Mito-Plt), a significant reversal of these biomarkers was noted, coincident with an improvement in cognitive deficits in T2DM mice. Significantly, the cuproptosis agonist elesclomol (ES) aggravated these alterations. …”
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  15. 115

    Anxiety-like behavior and altered hippocampal activity in a transgenic mouse model of Fabry disease by Kai Kummer, Jeiny Luna Choconta, Marie-Luise Edenhofer, Archana Bajpai, Gopuraja Dharmalingam, Theodora Kalpachidou, David A. Collier, Michaela Kress

    Published 2025-02-01
    “…Background: Fabry disease (FD) patients are known to be at high risk of developing neuropsychiatric symptoms such as anxiety, depression and cognitive deficits. Despite this, they are underdiagnosed and inadequately treated. …”
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  16. 116

    2-O-β-D-Glucopyranosyl-L-ascorbic acid, an ascorbic acid derivative isolated from the fruits of Lycium barbarum L., ameliorates high fructose-induced neuroinflammation in mice: inv... by Wei Dong, Yujia Peng, Guijie Chen, Zhiyong Xie, Weiqi Xu, Wangting Zhou, Jia Mi, Lu Lu, Yi Sun, Xiaoxiong Zeng, Youlong Cao, Yamei Yan

    Published 2024-01-01
    “…It was found that AA-2βG prevented HFrD-induced cognitive deficits. AA-2βG also predominantly enhanced the gut barrier integrity, decreased lipopolysaccharide entry into the circulation, which subsequently countered the activation of glial cells and neuroinflammatory response. …”
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  17. 117

    NRBF2 plays a crucial role in the acquisition process of learning and memory, independent of the Vps34 complex by Songfen Wu, Songfen Wu, Songfen Wu, Haicai Zhuang, Haicai Zhuang, Haicai Zhuang, Xidan Zhou, Kuan Li, Kuan Li, Kuan Li

    Published 2025-02-01
    “…Our results suggested that NRBF2 deletion impaired memory acquisition through an autophagy-independent pathway and provided novel insights into the role of NRBF2 in the central nervous system.DiscussionThis study offer new insights into the role of NRBF2 and highlight the potential of targeting NRBF2 as a therapeutic strategy for addressing cognitive deficits associated with various disorders.…”
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  18. 118

    Dyke-Davidoff-Masson syndrome: A rare case of hemiatrophy with chronic seizure disorder by Utkarsh Pradeep, Anjalee Chiwhane, Sourya Acharya, Pradeep Kumar, Paschyanti Kasat

    Published 2025-03-01
    “…Dyke-Davidoff-Masson syndrome (DDMS) is a rare neurological disorder characterized by cerebral hemiatrophy, leading to seizures, hemiparesis, and cognitive deficits. We report the case of a 20-year-old female with a history of chronic seizure disorder and left-sided hemiparesis. …”
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  19. 119

    Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer’s Disease by Anna Papazoglou, Julien Soos, Andreas Lundt, Carola Wormuth, Varun Raj Ginde, Ralf Müller, Christina Henseler, Karl Broich, Kan Xie, Dan Ehninger, Britta Haenisch, Marco Weiergräber

    Published 2016-01-01
    “…Gender-specific central dysrhythmia and network alterations in APPswePS1dE9 point to a functional role in behavioral and cognitive deficits and might serve as early biomarkers for AD in the future.…”
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  20. 120

    Trait Impulsivity Is Independent of Mild Cognitive Impairment in a Parkinson’s Disease Cohort by Ashani Jeyadevan, Megan C. Bakeberg, Michelle Byrnes, Jade Kenna, Soumya Ghosh, Rick Stell, Sue Walters, Tess Evans, Sarah McGregor, Malcolm Horne, Frank L. Mastaglia, Ryan S. Anderton

    Published 2019-01-01
    “…Patients with Parkinson’s disease (PD) commonly experience cognitive deficits and some also develop impulse control disorders (ICDs); however, the relationship between impulsivity and cognitive dysfunction remains unclear. …”
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