Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models by Lisa Blackmer-Raynolds, Lyndsey D. Lipson, Isabel Fraccaroli, Ian N. Krout, Jianjun Chang, Timothy Robert Sampson

“…Therefore, we performed an in-depth longitudinal study over 16 months, assessing cognition in these two strains, as well as assessments of motor function. While no cognitive deficits are observed in either genotype throughout the first year of life, 16-month-old APPSAA, but not APPWT mice show initial signs of spatial memory decline. …”
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Action Video Game Experience Related to Altered Large-Scale White Matter Networks by Diankun Gong, Weiyi Ma, Jinnan Gong, Hui He, Li Dong, Dan Zhang, Jianfu Li, Cheng Luo, Dezhong Yao

“…And various types of cognitive deficits are usually accompanied by impairments of WM networks. …”
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Enhancing vaccine clinical trials participation among elderly: challenges and strategies by Paul Gillard, Samer Nakhle, Darin Brimhall, Ouzama Henry, Narcisa Mesaros

“…However, unique challenges, including multi-morbidities, frailty, and ethically sound informed consent in those with cognitive deficits, require continuous careful reassessments and flexibility. …”
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Evaluation of the Fluctuation Mechanism of Behavioral Financial Market Based on Edge Computing by Xiaoliang Yuan

“…Investors always make decisions based on bounded rationality, cognitive deficits, and, ultimately, rationality. In order to avoid the complex and unpredictable risks of financial markets and understand their changing laws, the analysis of the characteristics of financial instability is conducive to understanding the nature and internal principles of financial markets. …”
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Responsiveness, Minimal Clinically Important Difference, and Validity of the MoCA in Stroke Rehabilitation by Ching-Yi Wu, Shuan-Ju Hung, Keh-chung Lin, Kai-Hua Chen, Poyu Chen, Pei-Kwei Tsay

“…The Montreal Cognitive Assessment (MoCA), a recently developed screening tool, is sensitive to poststroke cognitive deficits. The present study assessed its psychometric and clinimetric properties (i.e., responsiveness, minimal clinically important difference (MCID), and criterion validity) in stroke survivors receiving rehabilitative therapy. …”
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Decreased Taurine and Creatine in the Thalamus May Relate to Behavioral Impairments in Ethanol-Fed Mice: A Pilot Study of Proton Magnetic Resonance Spectroscopy by Su Xu PhD, Wenjun Zhu MS, Yamin Wan MD, PhD, JiaBei Wang PhD, Xi Chen PhD, Liya Pi PhD, Mary Kay Lobo PhD, Bin Ren PhD, Zhekang Ying PhD, Michael Morris MD, Qi Cao MD, PhD

“…Minimal hepatic encephalopathy is defined as hepatic encephalopathy with cognitive deficits and no grossly evident neurologic abnormalities. …”
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Verbal Memory Impairments in Children after Cerebellar Tumor Resection by Matthew P. Kirschen, Mathew S. Davis-Ratner, Marnee W. Milner, S. H. Annabel Chen, Pam Schraedley-Desmond, Paul G. Fisher, John E. Desmond

“…This study was designed to investigate cerebellar lobular contributions to specific cognitive deficits observed after cerebellar tumor resection. …”
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Impact of childhood trauma on cognitive function in patients with bipolar disorder by Zhiyang Zhang, Zhiyang Zhang, Chenyu Zhou, Chenyu Zhou, Zhen Mao, Zhen Mao, Yue Sun, Yue Sun, Lei Zhao, Lei Zhao, Tian Li, Tian Li, Chuanyue Wang, Chuanyue Wang, Qijing Bo, Qijing Bo

“…However, the association between childhood trauma as a risk factor for BD and cognitive deficits remains ambiguous.ObjectiveTo investigate the relationship between childhood trauma and cognitive function among patients with BD.MethodsThe study included 90 patients with BD and 94 healthy controls (HC). …”
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BMAL1 ameliorates type 2 diabetes-induced cognitive impairment via AREG upregulation and PI3K/Akt/GSK-3β pathway activation by Jialu Xu, Chunyu Li, Rongping Fan, Jiaxin Yin, Lei Xie, Xuemin Peng, Jing Tao, Weijie Xu, Shujun Zhang, Xiaoli Shi, Kun Dong, Xuefeng Yu, Xi Chen, Yan Yang

“…Our findings indicated that BMAL1 downregulation led to cognitive deficits, characterized by tau hyperphosphorylation and accumulated amyloid plaque. …”
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Virtual Compensatory Cognitive Training (Virtual-CCT) – A study on acceptability and feasibility by Subhashini Gopal, Lakshmi Venkatraman, B Suhavana, Pooja Sivaji, Frances Dark, Padmavati Ramachandran

“…Materials and Methods: Patients with a diagnosis of schizophrenia were assessed for their subjective and objective cognitive deficits. CCT was delivered for 13 participants as a virtual one – one session. …”
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A Review of Risk Factors and Predictors for Hemorrhagic Transformation in Patients with Acute Ischemic Stroke by Sneha E. Thomas, Noorine Plumber, Priyanka Venkatapathappa, Vasavi Gorantla

“…Acute ischemic strokes (AIS) and hemorrhagic strokes lead to disabling neuropsychiatric and cognitive deficits. A serious and fatal complication of AIS is the occurrence of hemorrhagic transformation (HT). …”
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A study on the exploration of mild cognitive impairment in Parkinson’s disease based on decision-making cognitive computing by Shouqiang Huang, Kai Li, Kai Li, Chen Wang, Jiakang Liu, Shuwu Li, Yuting Tu, Bo Wang, Huangqin Feng, Qin Yu, Hongzhou Lin, Yuzhe Xu, Jinghang Wu, Ting Zhang, Tong Chen

“…Unlike traditional methods, this study used digital dynamic assessment to reveal possible decision-making cognitive deficits in the PD-MCI populations, which provides new ideas for effective screening for PD-MCI.…”
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Characterization of visual cognition in pre-manifest, manifest and reduced penetrance Huntington’s disease by Rocio Del Pino, Maria Ángeles Acera, Amaia Ortiz de Echevarrría, Beatriz Tijero, Marta Ruiz-Lopez, Johanne Somme, Javier Ruiz-Martínez, Andrea Gabilondo, Ioana M. Croitoru, Lara Pardina, Naia Ayo-Mentxakatorre, Ane Murueta-Goyena, Iñigo Gabilondo, Rosario Sanchez-Pernaute, Tamara Fernández-Valle, Juan Carlos Gómez Esteban

“…We investigate the early presence of visual cognitive deficits in 181 participants, including HD carriers (40 pre-manifest, 30 early manifest, 27 manifest, and 6 reduced penetrance) and 78 healthy controls (HC). …”
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Dream Recall Frequencies and Dream Content in Wilson’s Disease with and without REM Sleep Behaviour Disorder: A Neurooneirologic Study by Gotthard G. Tribl, Mateus C. Trindade, Michael Schredl, Joana Pires, Iris Reinhard, Thais Bittencourt, Geraldo Lorenzi-Filho, Rosana Cardoso Alves, Daniel Ciampi de Andrade, Erich T. Fonoff, Edson Bor-Seng-Shu, Alexandre A. Machado, Manoel J. Teixeira, Egberto R. Barbosa

“…The reduction in dream length might reflect specific cognitive deficits in WD. The lack of differences regarding dream content might be explained by the established successful WD treatment. …”
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A High-Fat Diet Causes Impairment in Hippocampal Memory and Sex-Dependent Alterations in Peripheral Metabolism by Erica L. Underwood, Lucien T. Thompson

“…While high-fat diets are associated with rising incidence of obesity/type-2 diabetes and can induce metabolic and cognitive deficits, sex-dependent comparisons are rarely systematically made. …”
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Disability and its correlates among persons with bipolar disorder: Exploratory findings from the bipolar disorder course and outcome study from India (BiD-CoIN study) by Sandeep Grover, Ajit Avasthi, Rahul Chakravarty, Amitava Dan, Kaustav Chakraborty, Rajarshi Neogi, Avinash Desouza, Omkar Nayak, Samir Kumar Praharaj, Vikas Menon, Raman Deep, Manish Bathla, Alka A. Subramanyam, Naresh Nebhinani, Prasonjit Ghosh, Bhavesh Lakdawala, Ranjan Bhattacharya

“…In terms of correlates, those with a disability had a short duration of current remission, a higher number of manic and mixed episodes, a higher mean number of total episodes, spent more time in the episodes, had lower severity of the depressive episodes, higher residual depressive and manic symptoms, had overall higher manic affective morbidity, had a higher level of cognitive deficits, and had poorer insight. Conclusion: A significant proportion of patients with bipolar disorder have disability in work domain, and the presence of residual symptoms of either polarity are associated with higher level of disability.…”
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Сognitive Сomplaints with Unilateral Temporal Lobe Compression by M.U. Kaverina, U.V. Strunina, O.A. Krotkova

“… <p>Awareness of cognitive deficits, as a rule, occurs in the form of &laquo;memory complaints&raquo;. …”
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Patients with dementia with Lewy bodies display a signature alteration of their cognitive connectome by Roraima Yanez-Perez, Eloy Garcia-Cabello, Annegret Habich, Nira Cedres, Patricia Diaz-Galvan, Carla Abdelnour, Jon B. Toledo, José Barroso, Daniel Ferreira

“…However, the complex associations among cognitive deficits in different domains in DLB are largely unknown. …”
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Enhanced computerized cognitive remediation therapy improved cognitive function, negative symptoms, and GDNF in male long-term inpatients with schizophrenia by Peiyun Zhang, Lingyun Chen, Qianqian Qin, Chao Liu, Haijiao Zhu, Wenqing Hu, Wenqing Hu, Xinyu He, Kaihong Tang, Qi Yan, Hongmei Shen, Hongmei Shen

“…This study aimed to explore the efficacy of computerized cognitive remediation therapy (CCRT) on psychiatric symptoms, cognitive deficits, and serum levels of brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) in patients with schizophrenia.Materials and methodsForty male long-term institutionalized inpatients with schizophrenia were assigned to either a CCRT group (n = 20) or a control group (n = 20). …”
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Developmental lead exposure and aggression in male rats: Influences of maternal care and environmental enrichment by Shamaila Zafar, Courtney Williams, Jaehyun Joo, Blanca E. Himes, Jay S. Schneider

“…Developmental lead (Pb) exposure results in a variety of cognitive deficits and behavioral issues including increased antisocial behavior and aggression. …”
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