Spontaneous intracerebral hemorrhage: Recent advances and critical thinking on future clinical trial design by Wengui Yu, Michael J. Alexander, Ting Gao

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Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials by Deana S. Shenaq, Farbod Rastegar, Djuro Petkovic, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Ke Yang, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Tong-Chuan He

“…Here, we discuss the path towards the development of clinical trials utilizing BMSCs for orthopaedic applications. …”
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Open-label randomised clinical trial investigating whether robot-assisted kidney transplantation can reduce surgical complications compared to open kidney transplantation (ORAKTx): study protocol for a randomised clinical trial by Milla Ortved, Julia Dagnæs-Hansen, Hein V. Stroomberg, Thomas Kistorp, Malene Rohrsted, Søren Schwartz Sørensen, Andreas Røder

“…Trial registration The trial was prospectively registered with ClinicalTrials.gov on February 15th, 2023, with the identifier NCT05730257.…”
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Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy by Margrete Haram, Rune Hansen, Ola Finneng Myhre, Stian Solberg, Naseh Amini, Bjørn Atle Angelsen, Catharina de Lange Davies, Eva Hofsli

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Effects of Manual Acupuncture Versus Sham Acupuncture in patients with Post-Stroke Depression: A Randomized Clinical Trial by Conghui Wei, Jinling Chen, Qu Yang, Jingjing Xu, Qingsong Li, Fulin Li, Yu Liu, Jun Luo

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evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomat... by Jeffrey L. Cummings, Alireza Atri, Howard H. Feldman, Oskar Hansson, Mary Sano, Filip K. Knop, Peter Johannsen, Teresa León, Philip Scheltens

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Long-Term Effects of Sinus Floor Elevation with and Without Bone Graft: A Systematic Analysis of Randomized Clinical Trials by Andrei Paul Tent, Ioan Andrei Țig, Simion Bran, Andra Zlotu, Alexandru Mester, Florin Onisor

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Systematic review and meta-analysis of pain management after tonsillectomy by Katharina Geißler, Daniel Scham, Winfried Meißner, Peter Schlattmann, Orlando Guntinas-Lichius

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Short-term effects of 448 kilohertz radiofrequency stimulation on plantar fascia measured by quantitative ultrasound elastography and thermography on active healthy subjects: an open controlled clinical trial by Daniel Aguilar-Nuñez, Pablo Cervera-Garvi, Ana Gonzalez-Muñoz, Santiago Navarro-Ledesma

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Effects of B Vitamins on Symptoms and Cognitive Functions in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial by Somayeh Agmashe, Gita Sadighi, Narges Radman, Robabeh Mazinani

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Pooled safety analysis of two phase 3 studies investigating trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer by Julien Taieb, Marwan Fakih, Gabor Liposits, Gerald W. Prager, Eric Van Cutsem, Fortunato Ciardiello, Nadia Amellal, Elizabeth Calleja, Mei Liu, Lucas Roby, Josep Tabernero, Thierry André

Subjects: “…clinical trial…”
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The METEMP protocol: Massed exposure therapy enhanced with MDMA for PTSD by Jessica L. Maples-Keller, Boadie W. Dunlop, Barbara O. Rothbaum

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“Common sense is hard work” but benefits from persistent collaboration: Lessons learnt from the development of The Collaborative Network for European Clinical Trials for Children (c4c) to support the conduct of paediatric clinical trials of medicines by Sabah Attar, Carla Peacock, Mandy Wan, Erin Halil, Chloe Bickerstaff, Lionel Tan, Hafsah Bhatti, Ricardo M. Fernandes, Regis Hankard, Mark A. Turner

“…Contemporary Clinical Trials Communications…”
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Phase IV adaptive randomised clinical trials evaluating efficacy and cost-efficacy of pre-emptive pharmacogenetic genotyping strategies in the Spanish National Health System: iPHARMGx Master Protocol and PREVESTATGx nested clinical trial by Xandra García-González, Alberto M Borobia, Antonio J Carcas, Miriam Estébanez, Montserrat Carmona, Irene García García, Francisco Abad-Santos, Luis A López-Fernández, Esther Cubo, Iñaki Imaz-Iglesia, Alicia Marín-Candón, Miriam Saiz-Rodríguez, Irene Taladriz-Sender, Pedro Arias, Rocío Rosas-Alonso, Enrique Seco-Meseguer, Stefan Stewart, Elena Diago-Sempere, María del Mar García Saiz, Emilio J Laserna-Mendieta, Ana M Peiró, Magí Farré, Consuelo Rodriguez-Jimenez, Judith Sanabria-Cabrera, Lucia Pedrosa, Ignacio Bernardino, Javier Guiijarro-Eguinoa, Arturo Gómez López De Las Huertas, Susana Martín-López, Olga Hladun Alvaro, Vicente Arrate, Ana Fries, Daniel Rodriguez Díaz, Fernando Marqués García, Núria Alonso Pedrol, Modesto M Maestre Muñiz, Leticia Rodríguez Alcolado, Carlos Ortiz-Bautista, Angela Remesal-Doblado, María Isabel Lucena, Zaida Salmón González, Inmaculada Coca-Prieto

“…Trial registration of this study can be located at both the EU Clinical Trials Register available from https:// euclinicaltrials.eu/search-for-clinical-trials/?…”
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Systematic Review of Randomized Clinical Trials on Safety and Efficacy of Pharmacological and Nonpharmacological Treatments for Retinitis Pigmentosa by Marta Sacchetti, Flavio Mantelli, Daniela Merlo, Alessandro Lambiase

“…Methods. Randomized clinical trials on medical treatments for syndromic and nonsyndromic RP published up to December 2014 were included in the review. …”
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Prospective Clinical Trial for Septic Arthritis: Cartilage Degradation and Inflammation Are Associated with Upregulation of Cartilage Metabolites by Hagen Schmal, Anke Bernstein, Matthias J. Feucht, Benjamin Erdle, Jan M. Pestka, That Minh Pham, Eva Johanna Kubosch

“…Patients with acute joint infections were enrolled in a prospective clinical trial and the cytokine composition of effusions (n=76) was analyzed. …”
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Vitamin C–Based Gingival Depigmentation Versus Surgical Depigmentation: A Randomized Clinical Trial by Aehad Ul Haque, Nand Lal, Shalini Kaushal, Pavitra Rastogi, Rameshwari Singhal

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Diclofenac Potassium in Acute Postoperative Pain and Dysmenorrhoea: Results from Comprehensive Clinical Trial Reports by R. Andrew Moore, Sheena Derry

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Safety and immunogenicity of Ad26.COV2.S in adolescents: Phase 2 randomized clinical trial by Jelena Tica, Veronica V. Rezelj, Benoit Baron, Vitalija van Paassen, Javier Zaidman, Lee Fairlie, Gert Scheper, Mathieu Le Gars, Frank Struyf, Macaya Douoguih, Javier Ruiz-Guiñazú

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Comparison of Ticagrelor and Clopidogrel in Elective Coronary Stenting: A Double Blind Randomized Clinical Trial by Mohammadjavad Mehdizadeh Parizi, Reza Golchin Vafa, Amin Ahmadi, Reza Heydarzade, Mehrdad Sadeghi, Amin Khademolhossseini, Farhang Amiri, Soroush Khoshnood Mansorkhani, Ali Tavan, Nazanin Hosseini, Mohammad Montaseri, Seyed Ali Hosseini, Javad Kojuri

“…Methods. This randomized clinical trial was conducted from October 2022 to March 2023. …”
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