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  1. 61

    Efficacy of MI Paste® on Bleaching-Related Sensitivity: Randomized Clinical Trial by Shaista Rashid, Mohamed ElSalhy

    Published 2021-01-01
    “…This randomized controlled split-mouth clinical trial included 45 subjects that were randomly divided into two groups. …”
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    Critical Aspects of Clinical Trial Design for Novel Cell and Gene Therapies by Zinovia Kefalopoulou, Iciar Aviles-Olmos, Thomas Foltynie

    Published 2011-01-01
    “…Detailed evaluation of these discordant findings has highlighted several crucial issues such as patient selection criteria, details surrounding transplantation or gene therapy methodologies, as well as the study designs themselves that ought to be carefully considered in the planning phases of future clinical trials. Beyond the provision of symptomatic efficacy and safety data, it also remains to be identified whether the possibilities offered by stem cell and gene therapy technological advances might translate to meaningful neuroprotection and/or disease-modifying effects or alleviate the nonmotor aspects of PD and thus offer additional benefits beyond those achieved through conventional pharmacotherapy or deep brain stimulation (DBS).…”
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