Real-World Clinical Outcomes and Treatment Patterns Among Black and Non-Black Patients With Prostate Cancer Initiated on Apalutamide in a Urology Setting by Benjamin H. Lowentritt, Carmine Rossi, Erik Muser, Frederic Kinkead, Bronwyn Moore, Patrick Lefebvre, Dominic Pilon, Shawn Du

“…**Discussion:** While clinical trials have demonstrated the efficacy and safety of apalutamide, there is limited real-world data describing treatment persistence and clinical outcomes among patients with mCSPC and nmCRPC who initiated apalutamide. …”
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Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia by Olivia M. Depies, Qianqian Guo, Yuan Gao, Sutapa Sinha, Zhenqing Ye, Weiguo Han, Kari G. Rabe, Mingma S. Hoel, Heather C. Darby, Chuanhe Yu, Esteban Braggio, Sameer A. Parikh, Susan L. Slager, Neil E. Kay, Zhiquan Wang

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Efficacy and safety of upadacitinib in the treatment of moderate-to-severe atopic dermatitis: A systematic review. by Dan-Jie Zhao, Xia Li, Hai-Xia Lin, Hong Zheng, Di Zhou, Peng Tang

“…<h4>Methods</h4>PubMed, Medline, Embase, Web of Science, Clinical Trials Website, and Cochrane Library databases were searched from the time of establishment until January 6, 2024, to compile a list of all randomized controlled trials (RCTs) including upadacitinib in the treatment of moderate-to-severe AD. …”
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QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration by Jayshree Advani, Puja A. Mehta, Andrew R. Hamel, Sudeep Mehrotra, Christina Kiel, Tobias Strunz, Ximena Corso-Díaz, Madeline Kwicklis, Freekje van Asten, Rinki Ratnapriya, Emily Y. Chew, Dena G. Hernandez, Sandra R. Montezuma, Deborah A. Ferrington, Bernhard H. F. Weber, Ayellet V. Segrè, Anand Swaroop

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Complete metabolic response as early predictor of long-term efficacy after adoptive T cell therapy using tumor-infiltrating lymphocytes by Rikke Andersen, Troels Holz Borch, Eva Ellebaek, Inge Marie Svane, Helle Westergren Hendel, Kasper Madsen

“…In this study the predictive value of early metabolic response after TIL therapy is explored.Materials and methods: 60 patients treated with TIL therapy in 4 different clinical trials and with available [18F]2-fluoro-2-deoxy-d-glucose positron emission tomography-CT (FDG-PET/CT) scans at baseline and at least one follow-up scan 6–8 weeks and/or 12–16 weeks post-TIL infusion were included.Results: Obtaining complete metabolic response (CMR) was associated with significantly superior median overall survival (mOS) compared with not obtaining CMR (p&lt;0.0001). …”
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Comparing different montages of transcranial direct current stimulation on dual-task walking and cortical activity in chronic stroke: double-blinded randomized controlled trial by Pei-Ling Wong, Yea-Ru Yang, Shun-Chang Tang, Shih-Fong Huang, Ray-Yau Wang

“…Trial registration Thai Clinical Trials Registry (TCTR20180116001). Registered prospectively on 16th Jan, 2018 at http://www.thaiclinicaltrials.org .…”
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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

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The Role of Cardiac Resynchronization Therapy in Heart Failure: A Narrative Review by Olivier Uwishema, Ece Karabulut, Dalal Sheikhah, Burhan Kantawala, Misgana Gallo, Fatima Soufan, Magda Wojtara

“…This manuscript conducted a comparative analysis various hallmark clinical trials conducted in lieu of CRT, across many years (2002, 2003, 2004, 2005, 2017, 2018, 2020). …”
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Modular-based psychotherapy (MoBa) versus cognitive–behavioural therapy (CBT) for patients with depression, comorbidities and a history of childhood maltreatment: study protocol fo... by Elisabeth Schramm, Martin Hautzinger, Carolin Jenkner, Moritz Elsaesser, Sabine Herpertz, Hannah Piosczyk

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Comparison of Corneal Epitheliotrophic Factors of Undiluted Autologous Platelet-Rich Plasma and Autologous Serum Eye Drops for Dry Eye Disease by Passara Jongkhajornpong, Kaevalin Lekhanont, Sasivimol Rattanasiri, Prapaporn Pisitkun, Ammarin Thakkinstian

“…Trial registration ClinicalTrials.gov identifier, NCT04683796.…”
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Symptom-related experience and sexual health of female patients with pulmonary arterial hypertension: protocol for a systematic review and qualitative meta-synthesis by Ye He, Zhu Yang, Lixiao Yang, Fangfang Ma

“…A comprehensive search will encompass seven electronic databases and search engines (Ovid Medline, CINAHL, EMBASE, APA PsycINFO, Cochrane Database of Systematic Reviews, PubMed, Scopus) and grey literature sources (ProQuest Dissertations, ClinicalTrials.gov). Building on insights from previous reviews centred on symptom-related experience and sexual health. …”
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Safety Assessment of Glucose-Lowering Drugs and Importance of Structured Education during Ramadan: A Systematic Review and Meta-Analysis by Rashmi Shiju, Ayesha Akhil, Smitha Thankachan, Jaakko Tuomilehto, Monira Al Arouj, Abdullah Bennakhi

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Voices from the clinic: a qualitative analysis of physiotherapy strategies in musculoskeletal care for knee osteoarthritis patients by Jennifer Nguyen, Justine M. Naylor, Sarah Dennis, Rebecca Livings, Kathryn Mills, Siobhan M. Schabrun, Jeanette M. Thom

“…Trial registration This study was part of a larger study, with the full protocol published and registered at ClinicalTrials (ACTRN12620000188932, ACTRN12620000218998) 19/02/2020).…”
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Brief intervention to reduce fatigue impact in patients with inflammatory arthritis: design and outcomes of a single-arm feasibility study by Paul Ewings, Emma Dures, Sarah Hewlett, Joanna Thorn, Mwidimi Ndosi, Siobhan Creanor, Jo Adams, Lance M McCracken, Joe Lomax, Susan Bridgewater, Bryan Abbott, Alice Berry, Marie Urban

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Comparison of the safety of remimazolam and propofol during general anesthesia in elderly patients: systematic review and meta-analysis by Xianchun Liu, Longyi Zhang, Li Zhao, Xuelei Zhou, Wei Mao, Linlin Chen, Hongyu Zhu, Ying Xie, Linji Li

“…BackgroundRemimazolam is a novel sedative drug approved for procedural sedation and general anesthesia. Clinical trials have already explored its use in elderly patients for general anesthesia. …”
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Unlocking the full potential of resistance training: a comparative analysis of low- and high-intensity effects on neurotrophic growth factors and homocysteine by Chongwen Zuo, Yi Yin, Zhiyang Zheng, Ren Mu, Yuxin Liang, Shan Wang, Chaoqun Ye

“…Trial registration ClinicalTrials.gov ID: NCT06114550. Date of registration 01/30/2024.  …”
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Vertebral level in pregnancy according to the posterior superior iliac spine: an observational study by Ping Li, Dong Luo, Haibo Qu, Xuesheng Li, Linli Luo

“…Trial registration The study was registered in Chinese Clinical Trials Registry(Ref. ID: ChiCTR-DDD-16010067).…”
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Role of Tailored Timing and Frequency Prompts on the Efficacy of an Internet-Delivered Stress Recovery Intervention for Health Care Workers: Randomized Controlled Trial by Auguste Nomeikaite, Odeta Gelezelyte, Maria Böttche, Gerhard Andersson, Evaldas Kazlauskas

“…Trial RegistrationClinicalTrials.gov NCT05553210; https://clinicaltrials.gov/study/NCT05553210…”
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In vitro evaluation of the immunomodulatory and antibacterial activities of calcitriol (1,25-dihydroxy-vitamin D3) as a potential application for aerobic vaginitis treatment - prel... by Anna Tomusiak-Plebanek, Grażyna Więcek, Edyta Golińska, Magdalena Strus

“…However, conclusions regarding the potential use of calcitriol in the treatment of AV require further confirmation in in vivo studies as well as in well-designed clinical trials.…”
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Supporting implementation of universal prevention initiatives in K-12 schools: impacts on fidelity through organizational readiness and team functioning in a cluster-randomized tri... by Christopher M. Fleming, Hannah G. Calvert, Lindsey Turner

“…Trial registration This research was prospectively registered on ClinicalTrials.gov ( NCT03736395 ), on November 9, 2018.…”
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