Myoelectric pattern recognition with virtual reality and serious gaming improves upper limb function in chronic stroke: a single case experimental design study by Maria Munoz-Novoa, Morten B. Kristoffersen, Katharina S. Sunnerhagen, Autumn Naber, Max Ortiz-Catalan, Margit Alt Murphy

“…Trial Registration: ClinicalTrials.gov, reference number NCT04154371.…”
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Experimental hypothermia by cold air: a randomized, double-blind, placebo-controlled crossover trial by Ane M. Helland, Sigurd Mydske, Jörg Assmus, Guttorm Brattebø, Øystein Wiggen, Haakon K. Kvidaland, Øyvind Thomassen

“…We have developed a new method for clinical trials of experimental hypothermia, to enable further studies of active rewarming. …”
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Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres by Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

“…As IL-12-NS delivers logarithmically lower amounts of IL-12 than previously administered during human clinical trials, our data reflect the importance of IL-12-NS which safely create a systemic immunostimulatory environment.…”
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Efficacy of Patellar Taping and Electromyographic Biofeedback Training at Various Knee Angles on Quadriceps Strength and Functional Performance in Young Adult Male Athletes with Pa... by Shahnaz Hasan, Asma Alonazi, Shahnawaz Anwer, Azfar Jamal, Suhel Parvez, Faiz Abdulaziz Saleh Alfaiz, Heng Li

“…This trial is registered at Clinical Trials.gov under the identifier NCT05055284.…”
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Chemometric Methods—A Valuable Tool for Investigating the Interactions Between Antifungal Drugs (Including Antifungal Antibiotics) and Food by Agnieszka Wiesner-Kiełczewska, Paweł Zagrodzki, Alicja Gawalska, Paweł Paśko

“…The input dataset comprised information from published clinical trials, chemical records, and calculations. We constructed PLS models with changes in the pharmacokinetic parameters (∆AUC, area under the curve; ∆C_max, maximum drug concentration; and ∆T_max, time to reach maximum drug concentration) after dietary intervention as the response parameters and eight groups of molecular descriptors (M1–M8) as the predictor parameters. …”
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Vicarious trauma, coping strategies and nurses' health outcomes: An exploratory study by Ilenia Piras, Vanessa Usai, Paolo Contu, Maura Galletta

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The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial by Catherine M. Mewborn, Cutter A. Lindbergh, B. Randy Hammond, Lisa M. Renzi-Hammond, L. Stephen Miller

“…While results suggest that one year of L and Z supplementation may have limited effects on structural brain outcomes overall, there may be a subsample of individuals for whom supplementation of L and Z provides greater benefits. ClinicalTrials.gov number, NCT02023645.…”
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A laboratory feasibility study using a computer algorithm for anastomosis segmentation of epicardial ultrasonography images from distal coronary artery bypass anastomoses by Alex Skovsbo Jørgensen, Martin Siemienski Andersen, Lasse Riis Østergaard, Samuel Emil Schmidt, Dorte Nøhr, Jan Jesper Andreasen

“…Trial registration The study was registered on September 29, 2016, before enrolment of the first participant (ClinicalTrials.gov ID: NCT02919124).…”
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Role of Platelet-rich Plasma in Unexplained Recurrent Implantation Failure – A Systematic Review and Meta-analysis of Randomised Control Trials by Harpreet Kaur, Meenakshi Meenu, Shivam Pandey, Anil Chauhan, Mishu Mangla

“…Materials and Methods: An electronic database search for randomised clinical trials comparing PRP against routine care in women with unexplained RIF was performed on PubMed, EMBASE, SCOPUS and Cochrane Central. …”
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Clinical Burden of Chronic Obstructive Pulmonary Disease in Patients with Suboptimal Peak Inspiratory Flow by Jill A. Ohar, Donald A. Mahler, Gabrielle N. Davis, David A. Lombardi, Edmund J. Moran, Glenn D. Crater

“…To assess the clinical burden of COPD by characterizing the clinical characteristics of participants with sPIF against medium-low resistance DPIs versus those with optimal PIF (oPIF) from two phase 3 clinical trials. Methods. Baseline data were collected from two randomized, controlled, phase 3 trials (NCT03095456; NCT02518139) in participants with moderate-to-severe COPD. oPIF (60 L/min) against the medium-low resistance DPIs was used as the threshold for defining the PIF subgroups (<60 L/min (sPIF) vs ≥60 L/min (oPIF)). …”
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Enhance health evidence quality in classification tasks: A triangulation approach utilizing case-based reasoning and process features by Ruihua Guo, Ross Smith, Qifan Chen, Angus Ritchie, Simon Poon

“…Objective Machine learning (ML) has enabled healthcare discoveries by facilitating efficient modeling, such as for cancer screening. Unlike clinical trials, real-world data used in ML are often gathered for multiple purposes, leading to bias and missing information for a specific classification task. …”
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The Effect of Occupational Engagement on Lifestyle in Adults Living with Chronic Pain: A Systematic Review and Meta-analysis by Svetlana Solgaard Nielsen, Søren T. Skou, Anette Enemark Larsen, Alessio Bricca, Jens Søndergaard, Jeanette Reffstrup Christensen

“…We sought the databases Ovid MEDLINE, Embase, PsycINFO, CINAHL, Cochrane, Scopus, Web of Science, OTseeker, ClinicalTrials.gov, OpenGrey, and the web engine Google Scholar and citations and references of relevant publications. …”
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Patients´ experiences of TENS as a postoperative pain relief method in the post-anesthesia care unit after laparoscopic cholecystectomy: a qualitative study by Eva Angelini, Charlotta Josefsson, Cecilia Ögren, Paulin Andréll, Axel Wolf, Mona Ringdal

“…Trial registration The participants in the current study were retrospectively registered and recruited from a randomized controlled trial (RCT; registered at ClinicalTrials.gov: NCT04114149).…”
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The effect of magnesium supplementation on serum concentration of lipid profile: an updated systematic review and dose-response meta-analysis on randomized controlled trials by Mitra Hariri, Masoudreza Sohrabi, Ali Gholami

“…Methods In line with conducting this study first, relevant articles were found through searching databases, including five databases: Cochrane Library, ClinicalTrials.gov, ISI Web of Science, Scopus, and PubMed until January 2024. …”
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The Effect of Community Based Intervention on People with Type 2 Diabetes Mellitus: Systematic Review by M Agung Akbar, Junaiti Sahar, Etty Rekawati, Ratu Ayu Dewi Sartika, Prateek Gupta

“…Eligible studies included randomized controlled trials, mixed-methods research, clinical trials, prospective studies, experimental repeated-measures designs, and quasi-experimental designs. …”
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Pain medication tapering for patients with Persistent Spinal Pain Syndrome Type II, treated with Spinal Cord Stimulation: A RCT-study protocol of the PIANISSIMO study. by Maarten Moens, Cleo Lina Crunelle, Koen Putman, Elke Wuyts, Frenn Bultinck, Hubert Van Puyenbroeck, PIANISSIMO consortium, Lisa Goudman

“…<h4>Trial registration</h4>ClinicalTrials.gov NCT05861609. Registered on May 17, 2023.…”
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Comparing Prednisone and Methotrexate to Off-label Biologic Infliximab for Management of Ocular Uveitis: A Cost-minimization Analysis by William V. Padula, Miguel Cordero-Coma, Taygan Yilmaz, William V. Padula, Michéal J. Gallagher, Jonathan D. Campbell

“…As compared to prednisone, methotrexate was associated with increased costs and QALYs and was found to be a good value. Clinical trials of infliximab in the uveitis population are needed to reduce the uncertain estimates of inflixmab treatment success and the drug’s cost-effectiveness.…”
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Does the Harvesting Site Influence the Osteogenic Potential of Mesenchymal Stem Cells? by Van Thi Nguyen, Irene Tessaro, Antonio Marmotti, Camilla Sirtori, Giuseppe M. Peretti, Laura Mangiavini

“…The project number L1033 is registered with ClinicalTrials.gov NCT03369457.…”
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Endovascular versus Surgical Lower Extremity Revascularization among Patients with Chronic Kidney Disease by Qingzheng Chen, Jialin Han, Gomathy Parvathinathan, Elsie Ross, Margaret R. Stedman, Tara I. Chang

“…Multiple factors must be considered when counseling patients with CKD, who have a high burden of comorbid conditions. Clinical trials should include more patients with kidney disease, who are often otherwise excluded from participation, to better understand the most effective treatment strategies for this vulnerable patient population.…”
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Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine by Philip M Bath, Alan A Montgomery, Lisa J Woodhouse, Polly Scutt

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