Superior bioavailability of EPA and DHA from a L-lysine salt formulation: a randomized, three-way crossover study by Christiane Schön, Antje Micka, Vishnupriya Gourineni, Roberta Bosi

“…Conclusions: The study demonstrates that EPA and DHA lysine salt (Lys-FFA) offers superior bioavailability compared to EE and triglyceride forms, presenting a more effective supplementation option.German Clinical Trials Register, DRKS-ID: DRKS00029183…”
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LoVE4MUM Mobile App to Prevent Postpartum Depression: Protocol for a Pilot Randomized Controlled Trial by Siti Sabrina Kamarudin, Idayu Badilla Idris, Shalisah Sharip, Norfazilah Ahmad

“…Trial RegistrationClinicalTrials.gov NCT06366035; https://clinicaltrials.gov/study/NCT06366035 International Registered Report Identifier (IRRID)PRR1-10.2196/63564…”
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Use of Machine Learning to Predict Individual Postprandial Glycemic Responses to Food Among Individuals With Type 2 Diabetes in India: Protocol for a Prospective Cohort Study by Niteesh K Choudhry, Shweta Priyadarshini, Jaganath Swamy, Mridul Mehta

“…Trial RegistrationClinical Trials Registry-India CTRI/2022/02/040619; https://tinyurl.com/mrywf6bf International Registered Report Identifier (IRRID)DERR1-10.2196/59308…”
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Washout Duration of Prostaglandin Analogues: A Systematic Review and Meta-analysis by Vlad Diaconita, Matthew Quinn, Dania Jamal, Brad Dishan, Monali S. Malvankar-Mehta, Cindy Hutnik

“…Intraocular pressure (IOP) lowering effects in full responders are known to be 25–33% for this class; however, partial responders and nonresponders do exist. In clinical trials or prospective series, discontinuation and washout of PGAs is necessary to evaluate true change in IOP from novel surgeries and medical therapies. …”
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Effectiveness of cognitive–behavioural therapy: a protocol for an overview of systematic reviews and meta-analyses by Sarah E Lamb, Shona Kirtley, Beth Fordham, Thavapriya Sugavanam, Sally Hopewell, Karla Hemming, Jeremy Howick, Roshan das Nair, Julia Hamer-Hunt

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Finite element analysis of the influence of crown material on the stress distribution of dental implants by ZHUO Yingying, LIN Jie, CHEN Ruizhen, SHEN Jiyuan, LIN Ling, CAI Pingping, ZHENG Zhiqiang

“…Further research on long-term durability of PEEK and resin-matrix ceramicsis needed through practical and clinical trials.…”
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Economic Evaluation of Boceprevir for the Treatment of Patients with Genotype 1 Chronic Hepatitis C Virus Infection in Hungary by Raymond Odhiambo, Jagpreet Chhatwal, Shannon Allen Ferrante, Antoine El Khoury, Elamin Elbasha

“…**Background:** Recent international, randomized, placebo-controlled clinical trials (SPRINT-2; RESPOND-2) demonstrated that the triple combination of peginterferon (PEG), ribavirin (RBV) and boceprevir (BOC) was more efficacious than the standard dual therapy of PEG and RBV in treatment of patients chronically infected with genotype 1 hepatitis C virus (HCV) infection. …”
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Proseal laryngeal mask airway and endotracheal intubation in lower abdominal gynecological surgeries for perioperative gastric volume assessment and assessing postoperative recover... by Ranjay Mahaseth, Bhavna Gupta, Gaurav Jain, Anupama Bahadur, Deepak Singla, Debendra K. Tripathy

“…Methods: The study commenced after obtaining approval from Institutional Ethical Committee (IEC number-AIIMS/IEC/22/251 Date: 27/05/2022) and after registration in Clinical Trials Registry - India (CTRI) (CTRI/2022/07/044102 Registered on: 18/07/2022) and was conducted from August 2022 to August 2023. …”
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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

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The effects of dental implant macrodesign on the success of prosthetic replacement by Andrey N. Nikolaenko, Mikhail A. Postnikov, Nikolay V. Popov, Alexander P. Borisov, Anastasia A. Kiiko

“…However, there are not so many comparative clinical trials exploring the effects of the main characteristics of the implant on the success of prosthetic procedures. …”
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The effect of the use of omeprazole versus famotidine on the kidney transplant function: a randomized controlled study by Miłosz Miedziaszczyk, Marek Karczewski, Ilona Idasiak-Piechocka

“…There was no effect of famotidine or omeprazole on the function of the kidney transplant. ClinicalTrials.gov identifier: NCT05061303.…”
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Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy by Barbara Marschollek, Mathias Nelle, Martin Wolf, Stephan Baumgartner, Peter Heusser, Ursula Wolf

“…Clinical trials have reported statistically significant and clinically relevant effects of homeopathic preparations. …”
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Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data. by Lars Rejnmark, Lise Sofie Bislev, Kevin D Cashman, Gudny Eiríksdottir, Martin Gaksch, Martin Grübler, Guri Grimnes, Vilmundur Gudnason, Paul Lips, Stefan Pilz, Natasja M van Schoor, Mairead Kiely, Rolf Jorde

“…We performed a systematic quantitative review on characteristics of randomized clinical trials (RCTs) included in meta-analyses (MAs) on non-skeletal effects of vitamin D supplementation.…”
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Novel electroretinography devices to detect hydroxychloroquine retinopathy: study protocol for a diagnostic accuracy and feasibility study by James Galloway, Chan Ning Lee, Omar A Mahroo, Timothy L Jackson, George Murphy, Hatem A Wafa

“…Results will be published in a peer-reviewed ophthalmology journal.Trial registration number ClinicalTrials.gov NCT06035887.…”
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Unveiling unexpected adverse events: post-marketing safety surveillance of gilteritinib and midostaurin from the FDA Adverse Event Reporting database by Tingting Jiang, Yanping Li, Ni Zhang, Lanlan Gan, Hui Su, Guiyuan Xiang, Yuanlin Wu, Yao Liu

“…The common AEs of both drugs are consistent with previous clinical trials. Notably, we also revealed unexpected significant AEs for both drugs. …”
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Parkinson’s disease and other movement disorders in the context of the SARS-COV-2 pandemic by R. Kaladytė Lokominienė

“…Amantadine and memantine are presumed to have some anti-SARS-CoV-2 potential but this assumption should be confirmed in clinical trials. International Parkinson Disease and Movement Disorders Society has published recommendations and priorities for patients with Parkinson’s disease and other movement disorders during the COVID-19 pandemic which state that all measures of social distancing currently in place for the general population almost globally must be strictly and carefully practiced, direct consultations must be held in exceptional cases (e.g., for adjusting or checking deep brain stimulation programming, battery failure, levodopa duodenal pump treatments, botulinum toxin therapy), and patients should be encouraged to use sports equipment available at home and /or play virtual reality games. …”
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Psilocybin-assisted massed cognitive processing therapy for chronic posttraumatic stress disorder: Protocol for an open-label pilot feasibility trial. by Shakila Meshkat, Richard J Zeifman, Kathleen Stewart, Reinhard Janssen-Aguilar, Wendy Lou, Rakesh Jetly, Candice M Monson, Venkat Bhat

“…<h4>Trial registration</h4>ClinicalTrials.gov NCT06386003.…”
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Effect of Adding Silica Nanoparticles on the Physicochemical Properties, Antimicrobial Action, and the Hardness of Dental Stone Type 4 by Navid Aghbolaghi, Solmaz Maleki Dizaj, Ramin Negahdari, Amir Reza Jamei Khosroshahi, Yashar Rezaei, Sepideh Bohlouli, Mohammad Ali Ghavimi

“…Then, at least 2% silica nanoparticles are needed for a significant increase. Clinical trials are needed to enlarge for dental stone type 4 containing silica nanoparticles in the future.…”
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Single-Cell Analyses Reveal Necroptosis’s Potential Role in Neuron Degeneration and Show Enhanced Neuron-Immune Cell Interaction in Parkinson’s Disease Progression by Xiaomei Zeng, Zhifen Han, Kehan Chen, Peng Zeng, Yidan Tang, Lijuan Li

“…Our analyses provide insights into the causes of neuron death and inflammation in PD from single-cell resolution, which could be seriously considered in clinical trials.…”
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Leveraging mRNA technology for antigen based immuno-oncology therapies by Wei Zheng, Michele Ceccarelli, Charalampos S Floudas, Siranush Sarkizova

“…This review discusses the development and clinical application of mRNA vaccines in oncology, with a particular focus on recent clinical trials and the computational workflows and methodologies for identifying both shared and individual antigens. …”
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