The Reliability of the GNRB® Knee Arthrometer in Measuring ACL Stiffness and Laxity: Implications for Clinical Use and Clinical Trial Design by Kayla Smith, Nicole Miller, Steve Laslovich

“… # Purpose The aim of this study was to investigate the reliability of the GENOUROB, (GNRB®) knee arthrometer device in measuring both stiffness and laxity of the ACL, and to provide information on sample size calculation for future clinical trials. # Study Design Cross-sectional test-retest study # Method Twelve healthy student participants (age 24-30 years; 6 females and 6 males) completed testing on two different testing dates. …”
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Evaluation of direct pulp capping in carious primary molars: a 12-month randomized controlled clinical trial by Nayera T. El Saied, Salwa M. Awad, Ashraf Y. Alhosainy

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PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials by Samuel Pratama, Lowilius Wiyono, Martien Silviandy Setiawan, Brigitta Cindy Lauren

“…Results: Five randomized controlled clinical trials with 451 interventional patients and 308 control patients with SCLC were included. …”
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Challenges for funders in monitoring compliance with policies on clinical trials registration and reporting: analysis of funding and registry data in the UK by Rachel L Knowles, Frances Rawle, Kam Pou Ha, Julia Mueller, Rosa Parker

“…Objectives To evaluate compliance by researchers with funder requirements on clinical trial transparency, including identifying key areas for improvement; to assess the completeness, accuracy and suitability for annual compliance monitoring of the data routinely collected by a research funding body.Design Descriptive analysis of clinical trials funded between February 2011 and January 2017 against funder policy requirements.Setting Public medical research funding body in the UK.Data sources Relevant clinical trials were identified from grant application details, post-award grant monitoring systems and the International Standard Randomised Controlled Trial Number (ISRCTN) registry.Main outcome measure The proportion of all Medical Research Council (MRC)-funded clinical trials that were (a) registered in a clinical trial registry and (b) publicly reported summary results within 2 years of completion.Results There were 175 grants awarded that included a clinical trial and all trials were registered in a public trials registry. …”
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A Prospective and Controlled Clinical Trial on Stromal Vascular Fraction Enriched Fat Grafts in Secondary Breast Reconstruction by L. A. L. Tissiani, N. Alonso

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Demographic disparities in access to COVID-19 clinical trial sites across the United States: a geospatial analysis by Raphael Cuomo, Tiana McMann, Qing Xu, Zhuoran Li, Joshua Yang, Julie Hsieh, Christine Lee, Milena Lolic, Richardae Araojo, Tim Mackey

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Beta-Blockers for Primary Prevention of Anthracycline-Induced Cardiac Toxicity: An Updated Meta-Analysis of Randomized Clinical Trials by Armin Attar, Arman Karimi Behnagh, Mehrasa Hosseini, Foad Amanollahi, Paria Shafiekhani, Ali Kabir

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Nano-curcumin Effects on Ischemic Stroke clinical outcomes and Interleukin-6 Levels: Pilot Randomized Clinical Trial by Zeinab Ehtiatkar, Alia Saberi, Samaneh Ghorbani Shirkouhi, Mozaffar Hosseininezhad, Shahrokh Yousefzadeh-Chabok, Yaser Moadabi, Ashkan Karimi, Haniyeh Shadrou Gharani, Sasan Andalib

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Comparing the Effect of Intrathecal Injection of Pethidine with That of Bupivacaine on Hemodynamics in Hip Surgery: A Double Blinded Clinical Trial by Seyed Babak Mojaveraghili, Sina Hassannasab, Mansour Deylami, Tahereh Chavoshi, Avasadat Mirkatouli, Nasser Behnampour

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Collagenase Chemonucleolysis for Treating Cervical Disc Herniation: An Exploratory, Single-Arm, Open-Label, Multicenter Clinical Trial by Zhijian Wang, Bifa Fan, Lili Gu, Xuexue Zhang, Tao Sun, Hui Liu, Rongchun Li, Likui Wang, Kaiqiang Wang, Shun Li, Yong Ma, Haibo You, Daying Zhang

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Evaluation of Bacillus coagulans LMG S-31876 for immunomodulation and stress: a double-blind, placebo-controlled clinical trial by Ranjith Kumar Kallur, Sreenadh Madapati, Mayuri Banerjee, Ankita Mathur, Sourish Bhattacharya

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Comparison of three therapeutic interventions for chronic constipation in paediatric patients with cerebral palsy: a randomised clinical trial by Mohammad Hadi Imanieh, Mohammad Reza Golpayegan, Mostafa Sedighi, Kamal Ahmadi, Abbas Aghaie, Seyed Mohsen Dehghani, Gholamreza Yousefi

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Perceptions of Cardiovascular Healthcare Professionals Regarding Clinical Trials: A Survey-Based Study from the Middle East by Zainab Atiyah Dakhil, Hasan Ali Farhan, Mohammed Dheyaa Marsool, Mohammed Saad Qasim, Michele Peters, Jose Leal

“…There is a lack of data on insights of cardiologists in these countries regarding conducting and participating in clinical trials. We sought the views of cardiovascular healthcare professionals in Iraq on participation in clinical trials. …”
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Post-rectectomy choice of preventive intestinal stoma formation method: prospective multicenter randomized clinical trial protocol by P. V. Tsarkov, I. A. Tulina, P. B. Tsugulya, V. S. Kochetkov, S. V. Khmelik

“…To justify and present the protocol of the prospective, multicenter randomized clinical trial for evaluation of the choice of preventive intestinal stoma formation method after rectectomy. …”
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A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda by Keneth Iceland, Kasozi, Anne, Laudisoit, Lawrence Obado, Osuwat, Gaber El-Saber, Batiha, Naif E. Al, Omairi, Eric, Aigbogun, Herbert Izo, Ninsiima, Ibe Michael, Usman, Lisa M., DeTora, Ewan Thomas, MacLeod, Halima, Nalugo, Francis P., Crawley, Barbara E., Bierer, Daniel Chans, Mwandah, Charles Drago, Kato, Kenedy, Kiyimba, Emmanuel Tiyo, Ayikobua, Linda, Lillian, Kevin, Matama, Shui Ching, Nelly Mak, David, Onanyang, Theophilus, Pius, Linda, Lillian, Kevin, Matama, Shui Ching, Nelly Mak, David, Onanyang, Theophilus, Pius, David Paul, Nalumenya, Robinson, Ssebuufu, Nina Olivia, Rugambwa, Grace Henry, Musoke, Kevin, Bardosh, Juma John, Ochieng, Fred, Ssempijja, Patrick, Kyamanywa, Gabriel, Tumwine, Khalid J., Alzahrani, Susan Christina, Welburn

Subjects: “…COVID-19 clinical trials in resource poor countries…”
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Assessment of Opuntia ficus-indica supplementation on enhancing antioxidant levels by Rahela Zaman, Eugenie Sin Sing Tan, Normina Ahmad Bustami, Farahnaz Amini, Marjan Sadat Seghayat, Yu Bin Ho, Chung Keat Tan

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Efficacy of brain-computer interface training with motor imagery-contingent feedback in improving upper limb function and neuroplasticity among persons with chronic stroke: a doubl... by Myeong Sun Kim, Hyunju Park, Ilho Kwon, Kwang-Ok An, Hayeon Kim, Gyulee Park, Wooseok Hyung, Chang-Hwan Im, Joon-Ho Shin

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Nutritional safety and suitability of a specific protein hydrolysate manufactured by Fonterra Co‐operative Group Ltd derived from a whey protein concentrate and used in infant form... by EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, Angeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Laurence Castle, Mary Fewtrell, Hildegard Przyrembel, Ariane Titz, Dominique Turck

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From Lab to Clinic: Effect of Academia–Industry Collaboration Characteristics on Oncology Phase 1 Trial Entry by Wonseok Yang, Sang‐Won Lee

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Investigation on the occupational situation of clinical research associates in China by Can Du, Qi Han, Ziqian Lu, Jia Li

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