Sustainable reduction in sound levels on intensive care units through noise management - an implementation study by Sandra Witek, Claudia Schmoor, Fabian Montigel, Birgit Grotejohann, Sven Ziegler

“…Trial registration German Clinical Trials Register (DRKS): trial registration number: DRKS00025835; Date of registration: 12.08.2021.…”
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Perinatal emotional skills groups for women and birthing people with borderline personality disorder: outcomes from a feasibility randomised controlled trial by Paul Moran, Debra Bick, Lucy Biddle, Belinda Borries, Rebecca Kandiyali, Farah Mgaieth, Vivan Patel, Janice Rigby, Penny Seume, Vaneeta Sadhnani, Nadine Smith, Michaela Swales, Nicholas Turner

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How Many Diseases Are Colorectal Cancer? by A. Greystoke, S. A. Mullamitha

“…This disease heterogeneity leads to challenges in the design of clinical trials to assess novel therapies in the treatment of “colorectal cancer.”…”
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Pioglitazone versus Rosiglitazone: Effects on Lipids, Lipoproteins, and Apolipoproteins in Head-to-Head Randomized Clinical Studies by Mark A. Deeg, Meng H. Tan

“…In this review, we will focus on the randomized clinical trials that directly compared the lipid effects of the thiazolidinedione class of PPAR𝛾 agonists, pioglitazone and rosiglitazone, head-to-head either as monotherapy or in combination with other lipid-altering or glucose-lowering agents…”
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Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges by Shukui Zhou, Kaile Zhang, Anthony Atala, Oula Khoury, Sean V. Murphy, Weixin Zhao, Qiang Fu

“…In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy.…”
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Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis by Yirui Zhai, Liming Wang, Hong Zhao, Fan Wu, Lingxia Xin, Feng Ye, Wei Sun, Yan Song, Lijuan Niu, Huiying Zeng, Jingbo Wang, Yuan Tang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Hao Jing, Shunan Qi, Wenwen Zhang, Shulian Wang, Ye-Xiong Li, Jianxiong Wu, Bo Chen

“…This phase II trial shows that concurrent sorafenib and radiotherapy is effective and well-tolerated in the treatment of advanced HCC with portal vein or hepatic vein tumor thrombosis. Clinical trials registration: This study is registered at ClinicalTrials.gov (NCT03535259).…”
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Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis by Maria Inez Dacoregio, Isabella Michelon, Caio Ernesto do Rego Castro, Francisco Cezar Aquino de Moraes, Guilherme Rossato de Almeida, Lis Victória Ravani, Maysa Vilbert, Ricardo Lima Barros Costa

“…Methods: We comprehensively searched PubMed, Embase, and Cochrane databases, and ASCO and ESMO websites for clinical trials (CTs) assessing the safety of SG in BC patients. …”
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The recent landscape of RSV vaccine research by Karen Kelleher, Nadisha Subramaniam, Simon B. Drysdale

“…Recent advancements include nirsevimab, a long-acting mAb that has shown substantial efficacy in reducing medically attended RSV-related disease in infants, in phase III clinical trials, early regional and national real-world data. …”
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Automatic tool for the reconciliation of serious adverse events for pharmacovigilance: design and implementation of Reconciliaid by Sara Contu, Renaud Schiappa, Yann Chateau, Emmanuel Chamorey

“…Background: Reporting serious adverse events (SAEs) is crucial to reduce or avoid toxicities that can lead to major consequences for patient’s health due to treatments tested in clinical trials. Its exhaustiveness is often inadequate, and we observe discrepancies between data published by pharmacovigilance organizations and clinical databases. …”
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Screening for Atrial Fibrillation by Digital Health Technology in Older People in Homecare Settings: A Feasibility Trial by Edvard Liljedahl Sandberg, Sigrun Halvorsen, Trygve Berge, Jostein Grimsmo, Dan Atar, Bjørnar Leangen Grenne, Jarle Jortveit

“…Users of homecare services are often excluded from clinical trials due to advanced age, multimorbidity, and frailty. …”
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A Reduction in ADAM17 Expression Is Involved in the Protective Effect of the PPAR-α Activator Fenofibrate on Pressure Overload-Induced Cardiac Hypertrophy by Si-Yu Zeng, Hui-Qin Lu, Qiu-Jiang Yan, Jian Zou

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Influence of nutritional status on rehabilitation efficacy of patients after stroke—a scoping review by Huan Chen, Caihong Fu, Weihao Fang, Zhenyao Wang, Dawei Zhang, Hu Zhang

“…The selection was restricted to randomized controlled clinical trials, irrespective of language or publication date. …”
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Alloreactivity of Allogeneic Mesenchymal Stem/Stromal Cells and Other Cellular Therapies: A Concise Review by Kiran Shah, Nirali Shah, Fatameh Ghassemi, Carolyn Ly, Teena George, Carla Lutz, Huseyin Sumer

“…In the current pandemic, clinical trials have begun in many parts of the world to treat severe cases of COVID with MSCs. …”
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The work of return to work. Challenges of returning to work when you have chronic pain: a meta-ethnography by Martin Underwood, Mary Grant, Kate Seers, Robert Froud, Joanne O-Beirne-Elliman

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Awardee Summary of 2023 Taiwan Oncology Society Clinical Research Award Recipient: Persistent Endeavors on Research of Digestive Cancers for Three Decades by Kun-Huei Yeh

“…Our team has made persistent endeavors in translational research and clinical trials of digestive cancers for almost three decades. …”
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Comparison between relining of ill-fitted maxillary complete denture versus CAD/CAM milling of new one regarding patient satisfaction, denture retention and adaptation by Maha Nagy Mohamed Kamal

“…Trial registration Clinical trials number: NCT06366321. With registration date on ClinicalTrials.gov public website: 13/ 4/ 2024.…”
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Efficacy and safety of pharmacological treatments in inclusion body myositis: a systematic review by Pedro M Machado, Eduardo José Ferreira Santos, Nicholas Yapp, Pedro Sousa, Bayram Farisogullari, Hermaleigh Townsley

“…The search strategy was run on Cochrane Neuromuscular Disease Group Specialized Register, CENTRAL, MEDLINE and EMBASE, ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform. …”
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Predictors of hospitalization, death and incomplete/non-recovery from SARS-CoV-2 in an ambulatory global population by Sarah L. Pett

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Role of Signaling Transduction Pathways in Development of Castration-Resistant Prostate Cancer by Takahiro Inoue, Osamu Ogawa

“…Great advances in our understanding of the biological and molecular mechanisms of prostate cancer progression have resulted in many clinical trials of numerous targeted therapies. In this paper, we review mechanisms of CRPC development, with particular focus on recent advances in the understanding of specific intracellular signaling pathways participating in the proliferation of CRPC cells.…”
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Mesenchymal Stem Cells and Cardiovascular Disease: A Bench to Bedside Roadmap by Manuel Mazo, Miriam Araña, Beatriz Pelacho, Felipe Prosper

“…In this review, we will focus on their use in the therapy of myocardial infarction, looking at their characteristics, in vitro and in vivo mechanisms of action, as well as clinical trials.…”
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