Global burden of musculoskeletal disorders and attributable factors in 204 countries and territories: a secondary analysis of the Global Burden of Disease 2019 study by Binyan Wang, Ding Ye, Shiwen Liu, Shuzhen Fan, Yaxuan Wang, Yuxuan Zhan

Get full text

The efficacy and safety of CD7 chimeric antigen receptor T-cell therapy for hematologic malignancies: a systematic review and meta-analysis by Jile Liu, Yuxin An, Rui Sun, Xiaomei Zhang, Shujing Guo, Xuejin Gao, Mingfeng Zhao

“…IntroductionCD7 chimeric antigen receptor T-cell (CAR-T cell) therapy is an emerging method for treating hematological malignancies, and is another breakthrough in CAR-T cell therapy.MethodsThis study summarizes the currently published clinical research results on CD7 CAR-T cells and evaluates the safety and effectiveness of CD7 CAR-T cell therapy.ResultsAmong the 13 studies included in this study, a total of 200 patients received CD7 CAR-T cell therapy, including 88 patients who received autologous CAR-T cells, 112 patients who received donor derived CAR-T cells. 87% (80% -94%, I2=29.65%) of patients achieved complete remission. …”
Get full text

Soybean and avocado unsaponifiables: a review of their potential use in the treatment of osteoarthritis by Ana Sabucedo-Suárez, Ana Sabucedo-Suárez, Mónica López-Peña, Mónica López-Peña, María Permuy, María Permuy, Fernando Muñóz, Fernando Muñóz

“…Although results vary, pre-clinical research in different animal models has demonstrated positive effects, such as ameliorating histopathological changes and reduced inflammation. …”
Get full text

Abnormal expression of miR-668-3p in non-small cell lung cancer patients and its correlation with serum-related tumor markers by Wen Yang, Ling Liu, Jianliang Li, Yingchao Liu, Lin Rong, Junjie Ma, Rongchen Li, Qiuyue Zhang, Yugang Liu

Get full text

Analysis of clinical characteristics of hemorrhagic fever with renal syndrome with acute pancreatitis: a retrospective study by Lihua Huang, Min Xiao, Xiaoling Huang, Jun Wu, Jiao Luo, Fuxing Li, Wei Gu

Get full text

Plasma Diaphanous Related Formin 1 Levels Are Associated with Altered Glucose Metabolism and Insulin Resistance in Patients with Polycystic Ovary Syndrome: A Case Control Study by Xing Li, Mingyu Liao, Jiaqing Shao, Weixin Li, Liu Shi, Dong Wang, Juan Ni, Qiuyue Shen, Fan Yang, Guiliang Peng, Ling Zhou, Yuling Zhang, Zheng Sun, Hongting Zheng, Min Long

Get full text

The response of soil microbial community to application of organic amendment to saline land by Peifei Cong, Peifei Cong, Peifei Cong, Pengfei Huang, Zhisheng Huang, Zhisheng Huang, Zhisheng Huang, Zhisheng Huang

Get full text

Efficacy of acupuncture versus sham acupuncture or waitlist control for patients with chronic plantar fasciitis: study protocol for a two-centre randomised controlled trial by Yan Liu, Weiming Wang, Zhishun Liu, Liang Li, Sixing Liu, Zhiwei Zang, Weina Zhang

Get full text

Comparison of the Effect of Sertraline and Escitalopram on the Treatment of Major Depressive Disorder in Hemodialysis Patients: A Randomized Controlled Trial by Tahereh Sabaghian, Roya Vaziri-Harami, Seyed Alireza Ebadi, Minoo Heidari Almasi, Azadeh Ahmadi Koomleh, Amir Behnam Kharazmi, Ehsan Farhadi, Mahdiyeh Miri, Amir Ahmad Nassiri

Get full text

Clinical Significance of the Relationship between Progression-Free Survival or Postprogression Survival and Overall Survival in Patients with Extensive Disease-Small-Cell Lung Canc... by Hisao Imai, Keita Mori, Nodoka Watase, Sakae Fujimoto, Kyoichi Kaira, Masanobu Yamada, Koichi Minato

Get full text

Some Common SNPs of the T-Cell Homeostasis-Related Genes Are Associated with Multiple Sclerosis, but Not with the Clinical Manifestations of the Disease, in the Polish Population by Monika Chorąży, Natalia Wawrusiewicz-Kurylonek, Edyta Adamska-Patruno, Olga Zajkowska, Katarzyna Kapica-Topczewska, Renata Posmyk, Adam Jacek Krętowski, Jan Kochanowicz, Alina Kułakowska

Get full text

The embryological characteristics and clinical outcomes of oocytes with indented zona pellucida by Jie Lin, Lu Fang, Lv Yao, Haichao Wang, Hongyan Lan, Yinli Zhang, Xiaomei Tong

Get full text

An Injectable Hydrogel Bioimplant Loaded with Engineered Exosomes and Triple Anti-Tuberculosis Drugs with Potential for Treating Bone and Joint Tuberculosis by Huang J, Li H, Mei Y, Yi P, Ren Y, Wang Y, Han L, Tang Q, Liu D, Chen W, An Y, Hu C

“…Jiayan Huang,1,* Han Li,2,* Yuting Mei,1 Pengcheng Yi,1 Yunyao Ren,1 Yunjuan Wang,3 Limei Han,1 Qiusha Tang,3 Dongfang Liu,3 Wei Chen,4 Yanli An,5 Chunmei Hu1 1Department of Tuberculosis, the Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Department of Pharmacy, Central Hospital of Guangdong Provincial Nongken, Zhanjiang, Guangdong, People’s Republic of China; 3Medical School of Southeast University, Nanjing, People’s Republic of China; 4Department of Clinical Research Center, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 5Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Center of Interventional Radiology & Vascular Surgery, Department of Radiology, Medical School, Zhong da Hospital, Southeast University, Nanjing, Jiangsu People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunmei Hu, Department of Tuberculosis, the Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Zhongfu Road 1-1, Yijiangmen Street, Nanjing, Jiangsu Province, 210009, People’s Republic of China, Email njyy003@njucm.edu.cnPurpose: Treatment for bone and joint tuberculosis (BJTB) is challenging due to its refractory and recurrent nature. …”
Get full text

Preliminary Experiment on the Effect of 18% Substitute Salt on Home Blood Pressure Variability in Hypertensives by Jing Li, Lisha Mu, Huakun Rao, Yangfeng Wu, Hao Wang, Hongbing Tao, Lihong Mu

Get full text

The association between white blood cell counts and metabolic health obesity among US adults by Zhanbin Li, Zhanbin Li, Zhenyu Yao, Zhenyu Yao, Zhenyu Yao, Qiaoran Liu, Qiaoran Liu

Get full text

Receipt of long-acting injectable antiretroviral therapy among people with HIV in Southern US states: an assessment using electronic health records and claims data by Yiyang Liu, Rebecca J. Fisk-Hoffman, Maitri Patel, Robert L. Cook, Mattia Prosperi

“…Methods Leveraging EHRs from a large clinical research network in the Southern US - OneFlorida + linked with Medicaid (updated to 08/2022) - we identified a cohort of PWH who have been prescribed at least one dose of LAI ART since January 2021 and characterized their demographics, clinical characteristics, and HIV care outcomes. …”
Get full text

Classification of kinesiophobia in patients after cardiac surgery under extracorporeal circulation in China: latent profile and influencing factors analysis from a cross-sectional... by Qi Li, Rong Wang, Yanmei Gu, Tong Ren, Jing Jing Piao, Wenhui Xing, Yujing Liang

Get full text

A medical insurance fund operation performance evaluation system under the DRG payment mode reform by Zijian Wang, Zijian Wang, Zijian Wang, Weifu Chang, Weifu Chang, Aijing Luo, Aijing Luo, Aijing Luo

Get full text

Advances and Challenges in the Research of Integration Methods of Animal Experimental Evidence by ZHENG Qingyong, LI Tengfei, XU Jianguo, ZHOU Yongjia, MA Zhichao, WANG Na, LI Molan, YANG Wenjing, WU Peirun, WANG Haidong, TIAN Jinhui

“…However, the integration of evidence from animal experiments has faced numerous challenges, including insufficient emphasis, significant heterogeneity in study designs, high publication bias, and discrepancies with clinical research practices. This paper first identifies existing issues in the original research evidence from animal experiments, such as the selection and applicability of animal models, considerations in the design of experimental studies, and factors influencing the translation of animal experimental evidence. …”
Get full text

Development and Evaluation of a Mindfulness-Based Mobile Intervention for Perinatal Mental Health: Randomized Controlled Trial by Sehwan Park, Hee Young Cho, Jin Young Park, Kyungmi Chung, Kyungun Jhung

“…Trial RegistrationClinical Research Information Service KCT0007166; https://tinyurl.com/458vfc4r…”
Get full text