Additive impact of metabolic syndrome and sarcopenia on all-cause and cause-specific mortality: an analysis of NHANES by Meng Zhang, Qing-Yue Zeng, Linli Zhuang

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Analysis of syphilis epidemiological characteristics among the resident population in Ruian City, 2014‒2023 by HONG Wansheng, CHEN Jiangmin, ZHOU Limin, HU Yunlei, CHEN Chunnan, CHEN Liangchai, LI Jun, HUANG Jieru, ZHOU Zumu

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The protective role of SGLT2 inhibitors on aortic aneurysm mediated by oxidative stress and inflammation in type 2 diabetes mellitus by Rujie Zheng, Wenjuan Song, Jie Lu, Mingyue Yuan, Xiaotong Sun, Chengzhi Lu

“…Abstract Background Sodium-glucose transport protein 2 inhibitors (SGLT2i) have been widely used to treat patients with type 2 diabetes mellitus (T2DM) and have demonstrated protective effects against certain cardiovascular diseases. However, no clinical research has been conducted to explore the relationship between SGLT2i and the risk of aortic aneurysm (AA). …”
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Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning by Qianqian Liang, Yide Wang, Zheng Li, Zheng Li, Zheng Li, Zheng Li

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Genome-Wide Expression Difference of MicroRNAs in Basal Cell Carcinoma by Hai-Peng Wei, Song Zhan, Qing-An Zhu, Zhen-Juan Chen, Xian Feng, Jun-Yuan Chen, Qi-Lin Zhang, Jingjie Zhao, Lingzhang Meng

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Description and characterization of pneumococcal community acquired pneumonia (CAP) among radiologically confirmed CAP in outpatients by Josselin Le Bel, Juliette Pinot, Toni Alfaiate, Marie Ecollan, Fanny Cussac, Raphaël Pecqueur, Marie-Pierre Revel, Cyrille Vartanian, Emmanuelle Varon, Christian Theilacker, Xavier Duval, Henri Partouche, Cédric Laouénan, Serge Gilberg

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Epidemiological Changes in Hospitalized Bronchiolitis in Children Under 2 Years of Age in Hangzhou Before and After COVID-19 Restriction Easing by Xu X, Chen X, He J, Su L, Tong X, Sun Y, Huang S, Bai G, Chen Z

“…Xuchen Xu,1,* Xiya Chen,1,* Jing He,1,* Lin Su,1 Xudong Tong,2 Ying Sun,1 Shumin Huang,1 Guannan Bai,1 Zhimin Chen1 1Department of Pulmonology, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health., Hangzhou, Zhejiang, People’s Republic of China; 2Department of Paediatrics, Cixi Maternity and Child Health Care Hospital, Ningbo, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhimin Chen; Guannan Bai, Email zmchen@zju.edu.cn; guannanbai@zju.edu.cnBackground: Bronchiolitis is a common cause of hospitalization in infants under 2 years of age. …”
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Efficient and Effective Diabetes Care in the Era of Digitalization and Hypercompetitive Research Culture: A Focused Review in the Western Pacific Region with Malaysia as a Case Stu... by Boon-How Chew, Pauline Siew Mei Lai, Dhashani A/P Sivaratnam, Nurul Iftida Basri, Geeta Appannah, Barakatun Nisak Mohd Yusof, Subashini C. Thambiah, Zubaidah Nor Hanipah, Ping-Foo Wong, Li-Cheng Chang

“…This includes a scanning on the landscape of clinical research in DM, dimensions and spectrum of research misconducts, possible common biases along the whole research process, key preventive strategies, implementation and limitations toward high-quality research. …”
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Patients’ preferences for health insurance coverage of new technologies for treating chronic diseases in China: a discrete choice experiment by Jinsong Geng, Xiaowei Chen, Haini Bao, Danmin Qian, Yuting Shao, Hao Yu

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Clinical feasibility of deep learning-driven magnetic resonance angiography collateral map in acute anterior circulation ischemic stroke by Ye Jin Jeon, Hong Gee Roh, Sumin Jung, Hyun Yang, Hee Jong Ki, Jeong Jin Park, Taek-Jun Lee, Na Il Shin, Ji Sung Lee, Jin Tae Kwak, Hyun Jeong Kim

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Improvement in the effective cataract surgical coverage in Malaysia: evidence of impact from a mobile cataract outreach program by Mohamad Aziz Salowi, Nyi Nyi Naing, Norasyikin Mustafa, Wan Radziah Wan Nawang, Siti Nurhuda Sharudin, Mohd Aziz Husni

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Non-parathyroid hypercalcemia in a patient with new-onset hyperthyroidism and silicone-induced granulomas: case report by Laura Montefusco, Giada Rossi, Iulia Petria, Ida Pastore, Ida Pastore, Paolo Fiorina, Paolo Fiorina, Paolo Fiorina, Paolo Fiorina

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Vitrectomy combined with lens capsule flap transplantation in the treatment of high myopia macular hole retinal detachment: study protocol for a prospective randomised controlled t... by Xun Xu, Tianwei Qian, Hao Zhou, Weijun Wang, Ying Fan, Lin Xue, Xia Wu, Qiaoyun Gong, Luyao Ye

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RAGE and its ligands in breast cancer progression and metastasis by Madalina Coser, Bogdan Mihai Neamtu, Bogdan Mihai Neamtu, Bogdan Pop, Bogdan Pop, Calin Remus Cipaian, Calin Remus Cipaian, Maria Crisan, Maria Crisan

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Assessing Glioblastoma Treatment Response Using Machine Learning Approach Based on Magnetic Resonance Images Radiomics: An Exploratory Study by Amirreza Sadeghinasab, Jafar Fatahiasl, Marziyeh Tahmasbi, Sasan Razmjoo, Mohammad Yousefipour

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Therapists perspectives on the Early Intervention after Rape study: a qualitative process evaluation of a randomized controlled trial by Tina Haugen, Joar Øveraas Halvorsen, Oddgeir Friborg, Berit Schei, Cecilie Therese Hagemann, Marianne Kjelsvik

“…We used Thematic Analysis to identify themes and subthemes.Results: Thematic analysis yielded four significant themes for process evaluation: (1) The quality of the new intervention modified prolonged exposure was considered satisfactory through training and supervision and delivered with good adherence to the manual, although some therapists perceived the manual as too rigid; (2) Adoption dynamics within the SACs are complex and include both enthusiasm for clinical research as well as resistance to change; (3) Narrow inclusion criteria and burden with participation for patients may limit reach and representativeness of the RCT; (4) Unintended consequences were identified, such as delayed start, conflicting advices and cross-contamination, underscoring the ongoing necessity for process evaluation alongside RCTs.Conclusion: This qualitative process evaluation offers insight into real-world clinical challenges with implementing a new intervention and conducting a multisite RCT within SACs in Norway. …”
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Experiences of ‘traditional’ and ‘one-stop’ MRI-based prostate cancer diagnostic pathways in England: a qualitative study with patients and GPs by Fiona M Walter, Stephanie Archer, Willie Hamilton, Samuel William David Merriel, John McGrath, Alice S Forster, Hashim Uddin Ahmed, David Eldred-Evans

“…Objectives This study aimed to understand and explore patient and general practitioner (GP) experiences of ‘traditional’ and ‘one-stop’ prostate cancer diagnostic pathways in England.Design Qualitative study using semi-structured interviews, analysed using inductive thematic analysisSetting Patients were recruited from National Health Service (NHS) Trusts in London and in Devon; GPs were recruited via National Institute for Health Research (NIHR) Clinical Research Networks. Interviews were conducted in person or via telephone.Participants Patients who had undergone a MRI scan of the prostate as part of their diagnostic work-up for possible prostate cancer, and GPs who had referred at least one patient for possible prostate cancer in the preceding 12 months.Results 22 patients (aged 47–80 years) and 10 GPs (6 female, aged 38–58 years) were interviewed. …”
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Clinical Big Data and Deep Learning: Applications, Challenges, and Future Outlooks by Ying Yu, Min Li, Liangliang Liu, Yaohang Li, Jianxin Wang

“…Then, considering the wide range of clinical research and the diversity of data types, several deep learning applications for clinical data are illustrated: auxiliary diagnosis, prognosis, early warning, and other tasks. …”
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Tailoring traditional Chinese medicine in cancer therapy by Shuiquan Li, Xi Chen, Hui Shi, Ming Yi, Bing Xiong, Tianye Li

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Effects of Prone Positioning for Patients with Acute Respiratory Distress Syndrome Caused by Pulmonary Contusion: A Single-Center Retrospective Study by Xiaoyi Liu, Hui Liu, Shilian Liu, Wenlai Zhou, Qing Lan, Jun Duan, Xue Li, Xiangde Zheng

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