Ethnic disparities in rapid tranquillisation use and justifications in adult mental health inpatient settings: a systematic review and meta-analysis by Alessio Bricca, John Baker, Trine Munk-Olsen, Martin Locht Pedersen, Ole Schjerning, Frederik Alkier Gildberg

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Contribution of Arginine Catabolic Mobile Element and Copper and Mercury Resistance Element in Methicillin-Resistant Staphylococcus aureus: A Vantage Point by Parya Shokrollahi, Alka Hasani, Mohammad Aghazadeh, Mohammad Yousef Memar, Akbar Hasani, Maryam Zaree, Mohammad Ahangarzadeh Rezaee, Javid Sadeghi

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Association between Clinical Characteristics and Laboratory Findings with Outcome of Hospitalized COVID-19 Patients: A Report from Northeast Iran by Sahar Sobhani, Reihaneh Aryan, Elham Kalantari, Salman Soltani, Nafise Malek, Parisa Pirzadeh, Amir Yarahmadi, Atena Aghaee

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Academic Pressure and Psychological Imbalance in High School Students: Predictors of Depression via Polynomial Regression and Response Surface Analysis by Ye Y, Zhang Z, Tao Z, Liping C, Wang Y, Chen H, Li S, Chen X, Tang H, Zhou J, Zhou J

“…Yanyue Ye,1,* Zheng Zhang,1,* Zhen Tao,3 Cui Liping,2 Yuxin Wang,1 Hui Chen,1 Sihong Li,1 Xianliang Chen,1 Huajia Tang,1 Jiawei Zhou,1 Jiansong Zhou1,* 1Department of Psychiatry, the Second Xiangya Hospital of Central South University, National Center for Mental Disorders, National Clinical Research Center for Mental Disorders, Changsha, People’s Republic of China; 2Department of Psychiatry, Liuyang Brain Hospital, Liuyang, People’s Republic of China; 3Human Resources Department, Hebei Vocational University of Technology and Engineering, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiansong Zhou, Email zhoujs2003@csu.edu.cnObjective: The purpose of this study was to explore how the congruence between academic pressure and psychological imbalance affects depressive symptoms in adolescents and to further explore grade-level differences in these effects among high school students.Methods: The study population consisted of 29,975 high school students from 20 schools in Liuyang City, Hunan Province. …”
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Long-Term Survival in a Patient with Multiple Brain Metastases from Small-Cell Lung Cancer Treated with Gamma Knife Radiosurgery on Four Occasions: A Case Report by Ameer L. Elaimy, Sudheer R. Thumma, Andrew F. Lamm, Alexander R. Mackay, Wayne T. Lamoreaux, Robert K. Fairbanks, John J. Demakas, Barton S. Cooke, Christopher M. Lee

“…Further analysis and clinical research will be valuable in assessing the durability of multiple GKRS for brain metastases patients who experience long-term survival.…”
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Chinese expert consensus on vaginal self-sampling with high-risk human papillomavirus testing for cervical cancer screening by Linhong Wang, Yun Zhao, Beihua Kong, Ding Ma, Ruifang Wu, Hui Du, Xinfeng Qu, Lihui Wei, Long Sui, Mingzhu Li, Fanghui Zhao, Jingran Li

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Assessing health governance across countries: a scoping review protocol on indices and assessment tools applied globally by Kun Tang, Liyuan Zhang, Aidan Huang, Yuling Lin, Jingwen Dong, Qiwei He

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Prehospital Intubation in Patients with Isolated Severe Traumatic Brain Injury: A 4-Year Observational Study by Mazin Tuma, Ayman El-Menyar, Husham Abdelrahman, Hassan Al-Thani, Ahmad Zarour, Ashok Parchani, Sherwan Khoshnaw, Ruben Peralta, Rifat Latifi

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Epidemiology, clinical manifestation, diagnosis,and treatment of bursitis iliopectinea: A systematic review by Malgorzata Lea Jonczy, Lorenz Büchler, Yadusha Mahenthiran, Fabrice Helfenstein, Christian Apenzeller-Herzog, Andrej Isaak

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Observational study protocol: the faecal microbiome in the acute stage of new-onset paediatric type 1 diabetes in an Irish cohort by Eugene Dempsey, Catherine Stanton, Paul Ross, Colin Patrick Hawkes, Aonghus Lavelle, Carol-Anne O’Shea, Elaine Catherine Kennedy, Fiona Catherine Ross

“…Through this initial exploratory study, we aim to identify specific microbial biomarkers which may be used as future interventional targets throughout the various stages of T1D progression.Ethics and dissemination This study has been approved by the Clinical Research Ethics Committee of the Cork Teaching Hospitals. …”
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From fragmented to integrated healthcare managing hypertension post-stroke: a qualitative study by Hala F. Azhari, Jonathan Hewitt, Martin O'Neill, Alexander Smith, Terence Quinn, Jesse Dawson

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Rapid and accurate multi-phenotype imputation for millions of individuals by Lin-Lin Gu, Hong-Shan Wu, Tian-Yi Liu, Yong-Jie Zhang, Jing-Cheng He, Xiao-Lei Liu, Zhi-Yong Wang, Guo-Bo Chen, Dan Jiang, Ming Fang

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Cell therapy for scleroderma: progress in mesenchymal stem cells and CAR-T treatment by Liting Chen, Rongshan Huang, Chaoshuo Huang, Guiming Nong, Yuanyuan Mo, Lvyin Ye, Kunhong Lin, Anping Chen, Anping Chen

“…In the future, it is essential to strengthen integration of basic and clinical research, establish standardized protocols for cell preparation and quality control, develop personalized treatment plans, and rationally combine cell therapy with existing treatment methods to maximize its advantages and improve patient prognosis and quality of life.…”
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Application Progress of Transcranial Direct Current Stimulation Combined with Limb Therapy in Rehabilitation of Lower Limbs after Stroke by CHEN Hanbo, LU Xiao, ZHENG Wenhua, GUO Yongliang, YAN Tiebin

“…At present, this technique is widely used in clinical research. Transcranial direct current stimulation (tDCS) is widely used in combination with lower limb rehabilitation therapy because of its advantages such as high safety, easy to carry equipment and long delayed effect time. …”
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Expert consensus statement on risk management for scraping treatment (刮痧意外情况处理专家共识) by Beijing Office of Traditional Chinese Medicine Nursing Competence Improvement Project (北京市中医护理能力提升工程办公室，北京市中医技术质控中心)

“…Referring to the relevant national standards and domestic guidelines of scraping, combined with the actual clinical research results, the expert consensus statement was formulated to further standardize and guide the treatment of clinical scraping accidents and promote the further development of scraping technology. …”
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Burden and trends of dietary iron deficiency in the Middle East and North Africa region, 1990–2021 by Saeid Safiri, Saeid Safiri, Fatemeh Amiri, Nahid Karamzad, Nahid Karamzad, Mark J. M. Sullman, Mark J. M. Sullman, Ali-Asghar Kolahi, Morteza Abdollahi

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Impact of the Clinical Trials Act 2018 on clinical trial activity in Japan from 2018 to 2020: a retrospective database study using new and conventional Japanese registries by Hiroyuki Taruno, Mari S Oba, Osamu Takizawa, Kayoko Kikuchi, Kazuaki Matsui, Mayumi Shikano

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Safety of combined drug use in patients with cardiovascular and cerebrovascular diseases: an analysis based on the spontaneous reporting database of adverse drug reactions in Hubei... by Jia Wang, Yuhang Zhao, Zherui Chen, Rui Huang

“…Patients under 60 years old had a palpitations signal when combining eritrea bei sha Tanzania and felodipine (Ω 0.025:0.41, lift: 14.65, conviction: 3.8), and an erythema signal when combining nifedipine (Ω 0.025:0.23, lift: 8.17, conviction: 1.077).ConclusionAmong the 9 signals identified in this study, 4 were off-label adverse drug reactions that require further clinical research for exploration and confirmation, in order to provide more scientifically informed drug labeling. …”
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Serum metabolomic profiling for predicting therapeutic response and toxicity in breast cancer neoadjuvant chemotherapy: a retrospective longitudinal study by Zhihao Fang, Guohong Ren, Shouyu Ke, Qimin Xu, Yuhua Chen, Xiaoyuan Shi, Cheng Guo, Jian Huang

“…Although metabolic changes during cancer treatment are crucial determinant factors in therapeutic responses and toxicities, related clinical research remains limited. Methods One hundred paired blood samples were collected from 50 patients with LABC before and after a complete NACT treatment cycle. …”
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Effects of aquatic exercise compared with land-based exercise on the body composition and function of older adults with sarcopenia: protocol for a randomised controlled trial by Na Li, Fang Cheng, Jinfeng Yang, Yuanpeng Liao, PeiJie Sun, Weicheng Yang, Jinqi Yang, Jianxin Ran

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