Restrictive transfusion strategy for critically injured patients (RESTRIC) trial: a study protocol for a cluster-randomised, crossover non-inferiority trial by Kaori Ito, Kazuhiko Sekine, Hiroaki Iijima, Yutaka Kondo, Takashi Tagami, Mineji Hayakawa, Daisuke Kudo, Takayuki Ogura, Tetsuya Yumoto, Akira Endo, Yosuke Matsumura, Shigeki Kushimoto

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Antimicrobial Peptides: A Promising Alternative to Conventional Antimicrobials for Combating Polymicrobial Biofilms by Cesar Augusto Roque‐Borda, Laura Maria Duran Gleriani Primo, Kaila Petronila Medina‐Alarcón, Isabella C. Campos, Camila de Fátima Nascimento, Mauro M. S. Saraiva, Angelo Berchieri Junior, Ana Marisa Fusco‐Almeida, Maria José Soares Mendes‐Giannini, João Perdigão, Fernando Rogério Pavan, Fernando Albericio

“…Preclinical and clinical research is advancing, with animal studies and clinical trials showing promise against multidrug‐resistant bacteria and fungi. …”
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Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

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Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial by Thomas H. Marwick, Carolyn Lam, Yuxi Liu, Stefano Del Prato, Julio Rosenstock, Javed Butler, Justin Ezekowitz, Nasrien E. Ibrahim, W. H. Wilson Tang, Faiez Zannad, Riccardo Perfetti, James L. Januzzi

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Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-κB Pathway by Qingwen Zhang, Jinxia Sun, Yan Fu, Weigang He, Yinhong Li, Hongsheng Tan, Hongxi Xu, Xin Jiang

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Evaluating the relative predictive validity of measures of self-referential processing for depressive symptom severity by Ethel Siew Ee Tan, Hong Ming Tan, Kah Vui Fong, Sheryl Yu Xuan Tey, Nikita Rane, Chong Wei Ho, Zhao Yuan Tan, Rachel Jing Min Ong, Chloe Teo, Jerall Yu, Maxine Lee, An Rae Teo, Sin Kee Ong, Xin Ying Lim, Jin Lin Kee, Jussi Keppo, Geoffrey Chern-Yee Tan

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Acceptability of and experiences with menstrual hygiene cups among adolescent girls and young women aged 15–24 in two communities in Lusaka, Zambia: an exploratory study nested in... by Melleh Gondwe, Melvin Simuyaba, Mwelwa Phiri, Chisanga Mwansa, Albertus Schaap, Lucheka Sigande, Kwame Shanaube, Sian Floyd, Sarah Fidler, Helen Ayles, Musonda Simwinga, Bernadette Hensen

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Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China by Hongli An, Xiamei Kang, Chenhu Huang, Chenghao Jia, Jiaqi Chen, Yingying Huang, Qianzhe Cao, Yan Li, Biao Tang, Min Yue

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Relationship Between Sleep Time and Depressive Symptoms in Middle-Aged and Elderly Chinese: Mediating Role of Body Pain by Yang Z, Li B, Ma D, Lv Y, Qiu X, Zhang W, Wang J, Zhang Y, Xu C, Deng Y, Li J, Zhen X, Zhang J

“…Ziqing Yang,1,* Bingsong Li,2,3,* Dan Ma,1,4 Yitong Lv,1 Xinhui Qiu,5 Wenge Zhang,6 Jianye Wang,7 Yanlin Zhang,8 Chunming Xu,9 Yuxin Deng,9 Jinyang Li,10 Xuemei Zhen,2,3 Jun Zhang1 1Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, Shandong, People’s Republic of China; 2Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 3NHC Key Laboratory of Health Economics and Policy Research (Shandong University), Jinan, Shandong, 250012, People’s Republic of China; 4Department of Orthodontics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 5The second Hospital of Shandong University, Jinan, Shandong, 250033, People’s Republic of China; 6School of Management, Shandong University, Jinan, Shandong, 250100, People’s Republic of China; 7Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 8School of Basic Medical Sciences, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 9Department of Pediatrics, Xinjiang Medical University, Urumqi, People’s Republic of China; 10Faculty of Nursing, Shihezi University, Shihezi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuemei Zhen; Jun Zhang, Email zhenxuemei@sdu.edu.cn; zhangj@sdu.edu.cnObjective: Existing research has yet to adequately examine the correlation between sleep time, body pain, and depressive symptoms. …”
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Effect of home environment on neuropsychiatric development in preterm infants discharged from NICU at 18 months corrected age by Yuan Tian, Chuncao Zhang, Li Shen, Haifeng Jiang, Feng Liu, Jinjin Chen, Xia Hong

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Transarterial Chemoembolization Plus Radiofrequency Ablation and Iodine-125 Seed Implantation for Hepatocellular Carcinoma in High-Risk Locations: A Propensity Score-Matched Analys... by Zhang G, Ren Y, Liu J, Cao Y, Xiong F, Liang B, Zheng C, Kan X

“…Guilin Zhang,1– 3,* Yanqiao Ren,1– 3,* Jiayun Liu,1– 3 Yanyan Cao,1– 3 Fu Xiong,1– 3 Bin Liang,1– 3 Chuansheng Zheng,1– 3 Xuefeng Kan1– 3 1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Provincial Clinical Research Center for Precision Radiology & Interventional Medicine, Wuhan, 430022, People’s Republic of China; 3Hubei Province Key Laboratory of Molecular Imaging, Wuhan, 430022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuefeng Kan; Chuansheng Zheng, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, Hubei province, 430022, People’s Republic of China, Email xkliulang1314@163.com; hqzcsxh@sina.comBackground & Aims: The effect of transarterial chemoembolization (TACE) plus radiofrequency ablation (RFA) (TACE-RFA) for hepatocellular carcinoma (HCC) in high-risk locations is not satisfactory. …”
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Optimizing Neurobehavioral Assessment for Patients with Disorders of Consciousness: Proposal of a Comprehensive Pre-Assessment Checklist for Clinicians by Kristen Keech, Caroline Schnakers, Brooke Murtaugh, Katherine O’Brien, Beth Slomine, Marie-Michèle Briand, Rita Formisano, Aurore Thibaut, Anna Estraneo, Enrique Noé, Olivia Gosseries, Liliana da Conceição Teixeira

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Impact of a public health center nutrition education program on patients with type 2 diabetes in a primary care-based chronic disease management project: a pilot intervention study by Haerim Yang, Yoo Kyoung Park, Ji-hyun Lee, Hee-Sook Lim, Heejoon Baek, Hyejin Lee, Haeran Park, Pyunghwa Lee, Jooyoun Chung, Won Gyoung Kim

“…Trial Registration Clinical Research Information Service Identifier: KCT0010010.…”
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CD7‐targeting pro‐apoptotic extracellular vesicles: A novel approach for T‐cell haematological malignancy therapy by Bei Zhang, Jianqiang Chen, Jiming Chen, Yingying Shen, Yinghu Chen, Shibo Wang, Chengyan Zhang, Yuzhou He, Huajun Feng, Jiaoli Wang, Zhijian Cai

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Understanding HIV care providers’ support for tobacco cessation among people living with HIV in Western Kenya: a formative qualitative study by Peter Magati, Maya Vijayaraghavan, Elizabeth A Bukusi, Craig R Cohen, Starley B Shade, Zachary Arochi Kwena, Linet Ongeri, Francesca A Odhiambo, Cirilus O Ogala, Yvonne A Olando, Greshon Rota, Purba Chatterjee, Christine A Osula, Jerry J Nutor, Stella S Bialous

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Cardioprotective effect of crocin in patients with breast cancer receiving anthracycline-based chemotherapy: A randomized, double-blind, placebo-controlled study by Xinye Li, Xin Su, Wanping Liang, Li Wang, Chao Yuan, Juping Xu, Yijun Zhang, Yan Liu, Ning Ma, Fan Yang, Yiyuan Yang, Liyuan Tao, Shipeng Sun, Hongcai Shang, Yanwei Xing

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Protocol publication rate and comparison between article, registry and protocol in RCTs by Sylvain Mathieu, Jean-Baptiste Bouillon-Minois, Laurent Renard Triché, Emmanuel Coudeyre, De Chazeron Ingrid, Finotto Thomas, Catherine Laporte, Xavier Moisset, Ludovic Samalin, Guillaume Villatte, Bruno Pereira, Methodology And Evidence Statistics for Transparency in medical Research and Outcome reporting (MAESTRO) working group

“…Abstract Background Increasing transparency in clinical research is crucial to avoid misleading conclusions. …”
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Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway by Zhaowei Zou, Bin Liu, Lisi Zeng, Xianzi Yang, Renli Huang, Cheng Wu, Huijuan Zhu, Yi Gao, Dongdong Yuan, Jinlong Yu

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PD‐1+CD8+ T Cell‐Mediated Hepatocyte Pyroptosis Promotes Progression of Murine Autoimmune Liver Disease by Jie Long, Si‐Yu Yang, Zhen‐Hua Bian, Hao‐Xian Zhu, Min Ma, Xiao‐Qing Wang, Liang Li, Weici Zhang, Ying Han, M. Eric Gershwin, Zhe‐Xiong Lian, Zhi‐Bin Zhao

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Evaluating comparative effectiveness of psychosocial interventions for persons receiving opioid agonist therapy for opioid use disorder: protocol for a systematic review by Brian Hutton, Beverley Shea, Kimberly Corace, David Moher, Danielle B Rice, Becky Skidmore, Kednapa Thavorn, Sheena Taha, Dianna Wolfe, Fatemeh Yazdi, Beth A Sproule, Melanie Willows, Patricia Poulin, Gary Garber, Amy Porath, Leila Esmaeilisaraji

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