Inhibition of Kv1.3 channel restrains macrophage M2 polarization and ameliorates renal fibrosis via regulating STAT6 phosphorylation by Yanshan Chen, Yuanxing Zhi, Hailin Zhong, Liang Ma, Xinpei Gu, Yijing Cai, Jingjing Huang, Xin Yi, Xiaoyan Wu, Ken Kin Lam Yung, Pingzheng Zhou

“…Macrophages play crucial roles in regulating both homeostatic and inflammatory responses, with classical activated (M1) and alternatively activated (M2) subsets defined by the surrounding micro-environment. …”
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An improved DeepLabv3 + railway track extraction algorithm based on densely connected and attention mechanisms by Yanbin Weng, Jie Yang, Changfan Zhang, Jing He, Cheng Peng, Lin Jia, Hui Xiang

“…It achieves mIoU scores of 87.52% and 85.01%, along with accuracy rates of 97.59% and 94.84%, respectively. Compared to classical semantic segmentation networks such as U-Net and DeepLabv3 + , DA-DeepLabv3 + achieves higher extraction accuracy and shorter running time.…”
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Accurate and optimal control of a bidirectional DC-DC converter: A robust adaptive approach enhanced by particle swarm optimization by Julius Derghe Cham, Francis Lénine Djanna Koffi, Alexandre Teplaira Boum, Ambe Harrison, Paul Michael Dongmo Zemgue, Njimboh Henry Alombah

“…Unlike contemporary controllers, the proposed control strategy alleviates the chattering limitations of the classical sliding mode controller through the integration of a smooth hyperbolic tangent function. …”
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Algorithm of Strawberry Disease Recognition Based on Deep Convolutional Neural Network by Li Ma, Xueliang Guo, Shuke Zhao, Doudou Yin, Yiyi Fu, Peiqi Duan, Bingbing Wang, Li Zhang

“…Moreover, attention mechanism and central damage function are introduced into the classical convolutional neural network to solve the problem that the information loss of key feature areas in the existing classification methods of convolutional neural network affects the classification effect, and further improves the accuracy of convolutional neural network in image classification.…”
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Artificial intelligence for biodiversity: Exploring the potential of recurrent neural networks in forecasting arthropod dynamics based on time series by Sébastien Lhoumeau, João Pinelo, Paulo A.V. Borges

“…Although RNN did not surpass classical SARIMA in data prediction, it demonstrated superior goodness-of-fit on the training dataset. …”
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Zinner syndrome unveiled: Ectopic ureter and seminal vesicle cyst leading to urinary dysfunction: A case report by Zaid Sawaftah, Khaled Sawafta, Moath Hattab, Adel Abu Al Rub, Omar Sawafta, Jehad Khamaysa, Humam Emad Rajha, Jana Dibas, Muath Daraghmeh, Yazan Dibas

“…Physical examination revealed a left lower abdominal mass, and imaging confirmed the classic findings of ZS, including unilateral renal agenesis, an enlarged seminal vesicle cyst, and an ectopic ureter. …”
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Lateral Response Comparison of Unbonded Elastomeric Bearings Reinforced with Carbon Fiber Mesh and Steel by Ali Karimzadeh Naghshineh, Ugurhan Akyuz, Alp Caner

“…It has also been determined that the classical equation for lateral stiffness based on linear elastic behavior assumptions developed for elastomeric bearings does not always apply to the fiber-reinforced ones.…”
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Improving the Performance of Whale Optimization Algorithm through OpenCL-Based FPGA Accelerator by Qiangqiang Jiang, Yuanjun Guo, Zhile Yang, Zheng Wang, Dongsheng Yang, Xianyu Zhou

“…Meanwhile, other two classic algorithms including particle swarm optimization (PSO) and competitive swarm optimizer (CSO) are adopted for comparison. …”
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A Correlation Analysis-Based Structural Load Estimation Method for RC Beams Using Machine Vision and Numerical Simulation by Chun Zhang, Yinjie Zhao, Guangyu Wu, Han Wu, Hongli Ding, Jian Yu, Ruoqing Wan

“…The correlation analysis between current surface cracks of structures and external loads can provide important insights into determining the structural residual bearing capacity. The classical regression assessment method based on experimental data not only relies on costly structure experiments; it also lacks interpretability. …”
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Numerical Simulation of Nanosilica Sol Grouting for Deep Tunnels Based on the Multifield Coupling Mechanism by Dongjiang Pan, Kairong Hong, Helin Fu, Zhiguo Li, Limeng Zhang, Gaoming Lu, Feixiang Sun, Shiyu Wen

“…The rationality of this model is verified by classical Newtonian fluid grouting theory. The main conclusions: with the molar concentration as the index, the grout range can be divided into the raw grout region and the transition region; with the decrease of the grouting pressure, the growth rate of the normal grouting radius and the axial grouting radius will gradually decrease; due to the mechanical dispersion and molecular diffusion, the range of the transition region will gradually increase with time. …”
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Effects of Chronic Musculoskeletal Pain on Fertility Potential in Lean and Overweight Male Patients by Fereshteh Dardmeh, Hiva Alipour, Hans Ingolf Nielsen, Sten Rasmussen, Parisa Gazerani

“…Current level of chronic pain (visual analogue scale) and pressure pain thresholds (PPTs) in 16 predefined sites, classically described and tested as painful points on the lower body, were measured. …”
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Three-dimensional phase field simulation for rafting of multiparticle precipitate in elastic inhomogeneous alloy under external stress by Mao H., Kong Y., Shuai X., Tang S., Du Y.

“…The results show that the average particle size is linearly related to the evolution time and satisfies the Lifshitz-Slyozov-Wagner (LSW) classical coarsening theory when the external stress is not applied. …”
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Ichnologic and sedimentologic datasets from the Ediacaran–Cambrian Chapel island formation, Newfoundland, CanadaMendeley Data by Romain Gougeon, M. Gabriela Mángano, Luis A. Buatois, Guy M. Narbonne, Brittany A. Laing, Maximiliano Paz

“…The datasets are of importance to researchers interested in the palaeoecological signals depicted in this classic Ediacaran–Cambrian succession or in the compilation of worldwide data for deciphering macro-evolutionary trends in early animal life.…”
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Progesterone induces meiosis through two obligate co-receptors with PLA2 activity by Nancy Nader, Lama Assaf, Lubna Zarif, Anna Halama, Sharan Yadav, Maya Dib, Nabeel Attarwala, Qiuying Chen, Karsten Suhre, Steven Gross, Khaled Machaca

“…The steroid hormone progesterone (P4) regulates multiple aspects of reproductive and metabolic physiology. Classical P4 signaling operates through nuclear receptors that regulate transcription. …”
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Hypertension in Adults With Diabetes in Southeast Asia: A Systematic Review by Wei Jin Wong, Tan Van Nguyen, Fahed Ahmad, Huyen Thi Thanh Vu, Angela S. Koh, Kit Mun Tan, Ying Zhang, Christopher Harrison, Mark Woodward, Tu Ngoc Nguyen

“…A literature search was conducted in Ovid MEDLINE and Embase Classic + Embase from database inception until March 15, 2024. …”
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Six-Dimensional Pose Estimation of Molecular Sieve Drying Package Based on Red Green Blue–Depth Camera by Yibing Chen, Songxiao Cao, Qixuan Wang, Zhipeng Xu, Tao Song, Qing Jiang

“…To validate the effectiveness of the proposed method, 102 sets of experiments were conducted and compared with classical methods such as Fast Point Feature Histograms (FPFH) and Point Pair Features (PPF). …”
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Atherosclerosis and Rheumatoid Arthritis: More Than a Simple Association by Lorenzo Cavagna, Nicola Boffini, Giovanni Cagnotto, Flora Inverardi, Vittorio Grosso, Roberto Caporali

“…In fact, RA patients have an increased risk of cardiovascular events that is not fully explained by other classic cardiovascular risk factors. RA and atherosclerosis may share several common pathomechanisms and inflammation undoubtedly plays a primary role. …”
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HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas by M. J. Rutten, F. Dijk, C. D. Savci-Heijink, M. R. Buist, G. G. Kenter, M. J. van de Vijver, E. S. Jordanova

“…Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer samples and linked that to clinicopathological characteristics and survival. …”
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Brucellosis Presenting with Febrile Pancytopenia: An Atypical Presentation of a Common Disease and Review of Brucellosis by Carina Chang, Bryce D. Beutler, Mark B. Ulanja, Chukwudum Uche, Milan Zdrnja

“…A presumptive diagnosis is typically established through correlation of patient history and classic laboratory findings, which include transaminitis, anemia, and leukopenia with relative lymphocytosis. …”
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Distribution Pattern of Anchorage Stress and Water Sensitivity Analysis of Red Clay by Lifeng Li, Weili Gong, Huilin Deng, Xiaohu Zhang, Gan Li

“…Increase of the water content will lead to the rapid deterioration of the mechanical properties of red clay, which will lead to the reduction of the anchoring force of the slope anchor cable and lead to the failure of the support. Based on the classical Phillips and uniform anchorage shear stress distribution theory, this paper puts forward a uniform-exponential distribution pattern of anchorage shear stress according to the specific characteristics of red clay by using the characteristics of the peak shear strength and residual shear strength of the rock and soil mass. …”
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