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5161
Systematic review and bayesian network meta-analysis: comparative efficacy and safety of six commonly used biologic therapies for moderate-to-severe Crohn’s disease
Published 2025-01-01“…BackgroundIn contrast to previous network meta-analysis using classical frequentist methods, we evaluated the efficacy and safety of six frequently-used biologics through a Bayesian method.MethodsWeb of Science, Scopus, CENTRAL, ClinicalTrials.gov and ICTRP were searched to collect randomized controlled trials (RCTs) in adults with moderate-to-severe Crohn’s disease, comparing Infliximab, Adalimumab, Certolizumab pegol, Ustekinumab, Risankizumab, or Vedolizumab, relative to placebo or an active comparator for induction of clinical response (two different definitions) and maintenance of clinical remission. …”
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5162
Nebulized aminoglycosides for ventilator-associated pneumonia: Methodological considerations and lessons from experimental studies
Published 2025-01-01“…Based on experimental data obtained in animals with inoculation pneumonia, it challenges the classical belief that nebulization protects against systemic toxicity. …”
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5163
Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors
Published 2025-01-01“…The mechanisms underlying reported anti-inflammatory effects of IL-38 are thus still unclear, but seem unlikely to be mediated by classical IL-36R or IL-1R1 antagonism.…”
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5164
Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes
Published 2025-01-01“…The relationships between methylation status and classical dosage effect, dosage compensation, and inverse dosage effect were also studied. …”
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5165
Coincidental or Connected: Synchronous Giant Gastric GIST and Malignant Colonic Polyp: A Case Report
Published 2024-10-01“…Conversely, malignant polyps are epithelial tumours that arise from the colonic mucosa classically because of alterations in the APC tumour suppressor gene, resulting in overactivation of the Wnt/β-catenin signaling pathway. …”
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5166
Annual change in the distribution and landscape health of mangrove ecosystems in China from 2016 to 2023 with Sentinel imagery
Published 2025-01-01“…This study evaluated the potential of various classical deep learning models for annual mangrove identification in China and analyzed their changes from 2016 to 2023, with a specific focus on the landscape health of mangrove ecosystems within 37 natural reserves and non-reserves. …”
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5167
Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence
Published 2025-01-01“…GScore was significantly associated with neutrophils and non-classical monocytes. Potential agents including esmolol, estradiol, ganciclovir, and felbamate, targeting the 12 diagnostic signatures were identified. …”
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5168
Measurement-Based Prediction of mmWave Channel Parameters Using Deep Learning and Point Cloud
Published 2024-01-01“…Furthermore, a fusion method between the point clouds and images is proposed based on geometric relationship between the LiDAR and camera, to compress the size of the data collected. Second, based on a classic point cloud classification model (PointNet), we propose a novel regression PointNet model applied to channel parameter prediction. …”
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5169
Jianwei Xiaoshi oral liquid attenuates high-calorie diet-induced dyspepsia in immature rats via regulating the pancreatic secretion pathway and maintaining the homeostasis of intes...
Published 2025-01-01“…Abstract Background Jianwei Xiaoshi oral liquid (JWXS), a classical traditional prescription comprising various edible medicinal plants, has demonstrated significant efficacy in treating paediatric indigestion. …”
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5170
Stock price prediction with attentive temporal convolution-based generative adversarial network
Published 2025-03-01“…Traditional prediction models such as ARIMA and classic linear regression models are often inadequate for capturing the complex dynamics of stock prices. …”
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5171
Accelerated expansion of NATO into the Balkans as a consequence of Euro-Atlantic Discord
Published 2020-04-01“…The changes we are witnessing today are of the magnitude described by Paul Kennedy’s classic The Rise and Fall of the Great Powers. Georgia’s attack on South Ossetia crossed Russia’s red lines and exposed the latter’s ambitions to regain the superpower status; China symbolically showed the same ambition with the Olympics in Beijing; the crash of the US real-estate market triggered the global economic crisis; and the NATO-sponsored unilateral declaration of secession by Kosovo Albanians set a precedent and introduced uncertainty in international law and the entire system of United Nations. …”
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5172
Development of Personas and Journey Maps for Artificial Intelligence Agents Supporting the Use of Health Big Data: Human-Centered Design Approach
Published 2025-01-01“… BackgroundThe rapid proliferation of artificial intelligence (AI) requires new approaches for human-AI interfaces that are different from classic human-computer interfaces. In developing a system that is conducive to the analysis and use of health big data (HBD), reflecting the empirical characteristics of users who have performed HBD analysis is the most crucial aspect to consider. …”
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5173
Manière de dire et manière d’exercer la parenté en Kabylie. Pour une approche renouvelée du croisement genre et fait matrimonial
Published 2023-12-01“…Conversely, when viewed from the perspective of the female ego, the interpretation of kinship relations reveals aspects that dominant classical propositions have long prevented from being seen.…”
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5174
KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS
Published 2003-01-01“…PRODUCTION OF CULTURAL AND SYMBOLICAL CAPITAL: DISNEY'S PHENOMENON Gintautas Mažeikis Summary The classical conception of capital constructed by Marx and notions of cultural and symbolical capital suggested by P. …”
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5175
De organografía, organología y etnolaudería como propuesta para el estudio de los instrumentos musicales tradicionales
Published 2024-08-01“…Abstract In a review of the classical literature on traditional Mexican musical instruments, several results come to light: scholars, including myself, have spoken indistinctively of organography and organology as the conceptual and methodological frameworks for the study of the traditional musical instrument. …”
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5176
HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors
Published 2025-01-01“…HLA-DMB, the beta chain of the non-classical MHC class II protein HLA-DM, has been implicated in the progression of various cancers. …”
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5177
Estudio experimental del empuje sobre estructuras de contención en suelos reforzados con geomallas Experimental study of the lateral earth pressure on retaining structures in soils...
Published 2011-12-01“…In a first stage of research, samples without reinforcing are tested and the results are compared with those from classic earth pressure theories. Subsequently, results from lateral earth pressure tests in soils reinforced with one, two, three and four geogrids are presented. …”
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5178
THE INSTITUTIONALIZATION OF GLOBAL STRATEGIES FOR THE TRANSFORMATION OF SOCIETY AND EDUCATION IN THE CONTEXT OF CRITICAL THEORY
Published 2015-05-01“…In this context, the proposed integrative metatheory, which is based on classical and modern sources, concepts, aims for a comprehensive understanding and reconstruction of the phenomenon of education. …”
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5179
Environmental microbial communications in gram-positive and gram-negative bacteria
Published 2023-11-01“…Among those autoinducers, five major principal signal molecules are perturbed about side the classical quorum sensing system. The larger part of quorum sensing recognizing inhibitor takes bacterial quorum sensing share identifying as the even-handed and simply blocks the larger part recognizing plan of pathogenic organisms, which can demolish the pathogenicity of microorganisms without applying explicit squeezing factor, and doesn't execute the regular organisms or then again intrude with their standard physiological activities. …”
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5180
HIDRA3: a deep-learning model for multipoint ensemble sea level forecasting in the presence of tide gauge sensor failures
Published 2025-02-01“…<p>Accurate modeling of sea level and storm surge dynamics with several days of temporal horizons is essential for effective coastal flood responses and the protection of coastal communities and economies. The classical approach to this challenge involves computationally intensive ocean models that typically calculate sea levels relative to the geoid, which must then be correlated with local tide gauge observations of sea surface height (SSH). …”
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