The efficacy of cholecalciferol in the comprehensive treatment of patients with autoimmune diabetes by N.V. Pashkovska, I.O. Tsaryk

“…Vitamin D deficiency is a global issue negatively affecting the course of autoimmune diabetes, including classical type 1 diabetes mellitus (T1DM) and latent autoimmune diabetes in adults (LADA). …”
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Protective Effects of Two Safflower Derived Compounds, Kaempferol and Hydroxysafflor Yellow A, on Hyperglycaemic Stress-Induced Podocyte Apoptosis via Modulating of Macrophage M1/M... by Yuanping Li, Dan Zheng, Dayue Shen, Xilan Zhang, Xiaoyun Zhao, Hui Liao

“…The present research is aimed at exploring the effects of kaempferol (Ka) and hydroxysafflor yellow A (HSYA) on classically activated (M1)/alternatively activated (M2) macrophage polarization and podocyte apoptosis under hyperglycaemic conditions in vitro. …”
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Lower Kinetic Chain, Meet the Thinking Brain: A Scoping Review of Cognitive Function and Lower Extremity Injury Risk by Michaela A. Reyes, Mark O. Probasco, Trina N. Worby, Dylan E. Loertscher, Lyndsey K. Soderbeck, Wendy E. Huddleston

“…The classic model of non-contact ACL injury includes environmental, anatomical, hormonal and biomechanical risk factors which directly impact either the amount of stress placed on the ligament or the relative capacity of ligament to withstand the forces placed on it. …”
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CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids by Alexander Hennig, Laura Wolf, Beatrix Jahnke, Heike Polster, Therese Seidlitz, Kristin Werner, Daniela E. Aust, Jochen Hampe, Marius Distler, Jürgen Weitz, Daniel E. Stange, Thilo Welsch

“…Organoids could be categorized into the established quasimesenchymal, exocrine-like, and classical subtypes based on KRT81 and CFTR immunoreactivity. …”
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The role of mNGS in the diagnosis of talaromycosis and case series by Jing Zhao, Hui-Ting Su, Dong Zhang, Xue-Tong Li, Min-Ya Lu, Juan Du, Jia-Yu Guo, Yi Gao, Xin-Fei Chen, Dong-Hua Wen, Shi-Yu Jia, Yao Wang, Qi-Wen Yang

“…This study aimed to analyze four classic cases of Talaromyces marneffei infection diagnosed using metagenomic next-generation sequencing (mNGS) to improve understanding of its diagnosis and treatment. …”
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An investigation of machine learning methods applied to genomic prediction in yellow-feathered broilers by Bogong Liu, Huichao Liu, Junhao Tu, Jian Xiao, Jie Yang, Xi He, Haihan Zhang

“…The results indicated that classic methods, such as GBLUP and Bayesian, achieved superior prediction accuracy compared to ML methods in five of the eight traits. …”
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Beyond Dermatological Findings: Multisystem Involvement in Prolidase Deficiency by Ezgi Yalcin Gungoren, Zeynep Meric, Asena Pinar Sefer, Asuman Deveci Ozkan, Salim Can, Royala Babayeva, Nurhan Kasap, Ercan Nain, Esra Ozek Yucel, Ayca Kiykim, Sevgi Bilgic-Eltan, Ayse Deniz Yucelten, Elif Karakoc-Aydiner, Ahmet Ozen, Safa Baris

“…Conclusion: Beyond the well-known classical dermatological findings, the presence of recurrent opportunistic infections, gastrointestinal involvement, malignancy, and flow cytometry findings suggestive of combined immunodeficiency indicate that the diagnosis of prolidase deficiency may be underestimated. …”
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Herbal HuoXueTongFu Formula with anti-inflammatory and fibrinolytic activity regulation for the prevention of postoperative peritoneal adhesions by Lili Yang, Lili Yang, Yali Wang, Yali Wang, Zhengjun Li, Zhengjun Li, Wen Li, Yanqi Chen, Ziyang Kong, Huixiang Zhang, Jiafei Wu, Mingqi Shang, Ming Li, Yaoyao Bian, Yaoyao Bian, Yaoyao Bian, Li Zeng, Li Zeng

“…BackgroundThe HuoXueTongFu Formula (HXTF) originates from the classic prescription “DaHuangMuDan Decoction” from the “Synopsis of the golden chamber”. …”
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Evaluation of in-office tooth whitening treatment with violet LED: protocol for a randomised controlled clinical trial by Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Sandra Kalil Bussadori, Maria Fernanda Setúbal Destro Rodrigues, Ana Eliza Castanho Garrini dos Santos, Marcelo Mendes Pinto, Dácio Antonio Pantano Junior, Aldo Brugnera Jr, Fátima Antonia Aparecida Zanin

“…Colour will be measured at baseline, immediately after the first session and at the 15 and 180 days follow-up using the Vita Classical and the digital Easyshade V spectrophotometer (Vita, Zahnfabrik, Germany). …”
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Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma by Dengfeng Lu, Fei Wang, Yayi Yang, Aojie Duan, Yubo Ren, Yun Feng, Haiying Teng, Zhouqing Chen, Xiaoou Sun, Zhong Wang

“…COX analysis suggested that CMRGS was an independent risk factor for glioma prognosis and had a better predictive performance than several classical indicators. In addition, GSEA, immune infiltration analysis showed that CMRGS could differentiate the immune landscapes of patients in groups. …”
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Ethnobotany, floristic and phytochemical studies of medicinal plants used to treat uterine fibroids in Mbarara City, Uganda by Calton Nantinda, Esther Lynnet Kisakye, David Musana, Isaac Ssessanga, Ukashar Ssenabulya, Timothy Omara, Ivan Kahwa, Florence Nalimu

“…Leaves (47.6%), stems (17.5%) and flowers (9.5%) of herbs (61.7%), trees (23.4%) and shrubs (14.9%) were the primarily utilized plant parts for preparing decoctions that are administered orally (94%). Classical phytochemical screening of plant organs from the eight most cited species indicated flavonoids, phytosterols, terpenoids, saponins and alkaloids. …”
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Monitoring Moso bamboo (Phyllostachys pubescens) forests damage caused by Pantana phyllostachysae Chao considering phenological differences between on-year and off-year using UAV h... by Anqi He, Zhanghua Xu, Yifan Li, Bin Li, Xuying Huang, Huafeng Zhang, Xiaoyu Guo, Zenglu Li

“…The results demonstrate that classical machine learning and deep learning models can effectively detect P. phyllostachysae damage, with the 1D-CNN algorithm achieving the best performance. …”
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Decoding the anomalies: a genome-based analysis of Bacillus cereus group strains closely related to Bacillus anthracis by Thuto Gomolemo Magome, Marius Surleac, Marius Surleac, Ayesha Hassim, Cornelius Carlos Bezuidenhout, Henriette van Heerden, Kgaugelo Edward Lekota

“…Taxonomic challenges persist due to inconsistent classification methods, particularly for B. cereus isolates that resemble B. anthracis in genetic clustering.MethodsThis study investigated B. cereus group isolates from blood smears of animal carcasses in Kruger National Park, uncovering an unusual isolate with B. cereus features based on classical microbiological tests yet B. anthracis-like genomic similarities with an Average Nucleotide Identity (ANI) of ≥95%. …”
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Collection of microorganisms of ICG SB RAS as a genetic resource for biotechnology by A. V. Bryanskaya, Y. E. Uvarova, A. S. Rozanov, N. M. Slynko, V. N. Shlyakhtun, K. V. Starostin, E. A. Demidov, E. V. Lazareva, O. P. Taran, S. E. Peltek

“…The value of the collection of microorganisms of the FRC ICG SB RAS as a genetic resource for biotechnology and bioengineering is determined not only by the species diversity of its strains, but also by a wide range of their area isolation and by the depth of their characterization using the widest arsenal of both classical and modern methods (including methods of genomics, proteomics, transcriptomics and bioinformatics).…”
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Clinical Practice Guidelines of Russian Gastroenterological Association, Scientific Society for the Clinical Study of Human Microbiome, Russian Society for the Prevention of Non-Co... by V. T. Ivashkin, T. L. Lapina, I. V. Maev, O. M. Drapkina, R. S. Kozlov, A. A. Sheptulin, A. S. Trukhmanov, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, D. S. Bordin, N. N. Dekhnich, I. L. Klyaritskaya, N. V. Korochanskaya, M. F. Osipenko, E. A. Poluektova, A. S. Sarsenbaeva, V. I. Simanenkov, A. V. Tkachev, A. I. Ulyanin, I. B. Khlynov, V. V. Tsukanov

“…The first line therapy for Н. pylori infection eradication is the standard triple therapy including a proton pump inhibitor (PPI), clarithromycin and amoxicillin, enhanced with bismuthate tripotassium dicitrate. A classic four-component therapy based on bismuthate tripotassium dicitrate or quadrotherapy without bismuth drug products which includes PPI, amoxicillin, clarithromycin and metronidazole, may be used as alternative to the first line eradication therapy. …”
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A child with Chronic Nonbacterial Osteomyelitis and celiac disease: accidental association or two different aspects of the same condition? by Grazia Bossi, Maria Sole Prevedoni Gorone, Luca Lungarotti, Francesco Pelillo, Amelia Mascolo, Matteo Naso, Daniele Veraldi, Francesca Olivero, Costanza Chirico, Maria Vittoria Marino, Cristina Dutto, Gian Luigi Marseglia

“…She had never complained of abdominal pain or other gastro-intestinal symptoms. WBMR showed the classical features of multifocal CNO, and biopsy confirmed the diagnosis. …”
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Treatment of Helicobacter pylori infection: mainstream and innovations (Review of the literature and Russian gastroenterological association Advisory council resolution, May 19, 20... by V. T. Ivashkin, I. V. Mayev, T. L. Lapina, A. A. Sheptulin, A. S. Trukhmanov, R. A. Abdulkhakov, S. A. Alekseyenko, N. N. Dekhnich, R. S. Kozlov, I. L. Klyaritskaya, S. A. Kurilovich, M. F. Osipenko, V. I. Simanenkov, I. B. Khlynov

“…At prescription of standard triple therapy various measures increasing its efficacy should be utilized. Classical fourcomponent bismuth tripotassium dicitrate­based treatment or quadrotherapy without bismuth including PPI, amoxicillin, clarithromycin and metronidazole may be alternative options for the first line eradication therapy. …”
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A Novel Convolutional Neural Network-Based Approach for Fault Classification in Photovoltaic Arrays by Farkhanda Aziz, Azhar Ul Haq, Shahzor Ahmad, Yousef Mahmoud, Marium Jalal, Usman Ali

“…An in-depth quantitative evaluation of the proposed approach is presented and compared with previous classification methods for PV array faults – both classical machine learning based and deep learning based. …”
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Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway by Tingting Zhang, Mengmeng Zhu, Jialing Ma, Zhenghong Liu, Zhidan Zhang, Meijie Chen, Yaping Zhao, Huaxin Li, Shengnan Wang, Xiaoning Wei, Wenwen Zhang, Xiaoxiao Yang, Peter J. Little, Danielle Kamato, Hao Hu, Yajun Duan, Baotong Zhang, Jianbo Xiao, Suowen Xu, Yuanli Chen

“…We further validated the participation of Moscatilin-inhibited vascular calcification by the classical WNT/β-catenin pathway, among which WNT3 played a key role in this process. …”
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A comparative analysis of five land surface temperature downscaling methods in plateau mountainous areas by Ju Wang, Ju Wang, Ju Wang, Bo-Hui Tang, Bo-Hui Tang, Bo-Hui Tang, Bo-Hui Tang, Xinming Zhu, Xinming Zhu, Xinming Zhu, Dong Fan, Dong Fan, Dong Fan, Menghua Li, Menghua Li, Menghua Li, Junyi Chen, Junyi Chen, Junyi Chen

“…Three machine learning models, including Back Propagation (BP) Neural Network, random forest (RF), and extreme gradient boosting (XGBoost), and two classic single-factor linear regression models (DisTrad and TsHARP) were compared. …”
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