Les territoires de l’agrobusiness au Brésil by Denise Elias

“…The effects on production, society and space are many and complex. With all this, the classical location factors are resized, occurring new possibilities for production and hence a real spatial dispersion of production and a reorganization of the territory. …”
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Role of sirtuins in epigenetic regulation and aging control by E. M. Samoilova, S. E. Romanov, D.  A. Chudakova, P. P. Laktionov

“…As is expected, the activity of sirtuin proteins affects the manifestation of classic signs of aging in the body, such as cellular senescence, metabolic disorders, mitochondrial dysfunction, genomic instability, and the disruption of epigenetic regulation. …”
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Geodesic Distance on Gaussian Manifolds to Reduce the Statistical Errors in the Investigation of Complex Systems by Michele Lungaroni, Andrea Murari, Emmanuele Peluso, Pasqualino Gaudio, Michela Gelfusa

“…In particular, since some time it has emerged quite clearly that even slightly departures from normality and homoscedasticity can affect significantly classic significance tests. Robust statistical methods have been developed, which can provide much more reliable estimates. …”
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The Life Functioning Scale: A Measurement Tool Developed to Assess the Physical Functioning Abilities of Community-Dwelling Adults Aged 50 Years or Older by Yunhwan Lee, Eunsaem Kim, Jihye Yun, Jaewon Choi, Jinhee Kim, Chang Won Won, Miji Kim, Soongnang Jang, Kyungwon Oh, Jihee Kim

“…The final 25-item questionnaire was tested on an independent sample (n=259) for validity and reliability based on classical test and item response theories. Predictive validity at the 6-month follow-up was tested in a separate sample (n=263). …”
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Rapid assessment of main agronomic indicators in the grain of winter and spring forms of triticale using infrared spectroscopy by V. S. Popov, N. G. Konkova, T. V. Shelenga, V. I. Khoreva, I. A. Kibkalo, M. Kh. Gadjimagomedova, L. G. Suvaryan

“…Calibration models for the assessment of the said agronomic characters in triticale grain were developed on the platform of the MATRIX-I IR analyzer (Bruker Optics, Germany) and based on the values obtained by classical methods of biochemical analysis adopted at VIR. …”
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Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen by Michael L. McCaleb, Steven G. Hughes, Tamar R. Grossman, Ashley Frazer-Abel, Bill Jung, Lixuan Yin, Scott P. Henry, Brett P. Monia, Eugene Schneider, Richard Geary, Gary T. Brice

“…There was a strong correlation between reduction of plasma levels of FB and alternative complement pathway activity (AH50), but no meaningful changes in classical complement pathway activity (CH50). The long duration of lowering of FB levels following the last dose supports monthly dosing in future clinical trials. …”
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The Ischial Spine in Developmental Hip Dysplasia: Unraveling the Role of Acetabular Retroversion in Periacetabular Osteotomy by Gerard El-Hajj, Hicham Abdel-Nour, Rami Ayoubi, Joseph Maalouly, Fouad Jabbour, Raja Ashou, Alexandre Nehme

“…In a previous paper, we reported the classic coxometric measurements of 178 patients with symptomatic hip dysplasia undergoing PAO where retroversion was noted in 42% of the cases and was not found to be a major factor in the appearance of symptoms. …”
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Spatial-temporal characteristics and influencing factors of farmland carbon emissions in Guangdong Province, China by Zihao Chao, Zihao Chao, Zihao Chao, Ziyang Zhu, Ziyang Zhu, Ziyang Zhu, Yuchen Li

“…This study calculated the farmland carbon emissions in Guangdong from 2011 to 2021 using the classical IPCC carbon emission calculation methodology. …”
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Physics-Based Compact Model of Independent Dual-Gate BEOL-Transistors for Reliable Capacitorless Memory by Lihua Xu, Kaifei Chen, Zhi Li, Yue Zhao, Lingfei Wang, Ling Li

“…Capacitorless DRAM architectures based on Back-End-of-Line (BEOL)-transistors are promising for long-retention, high-density and low-power 3D DRAM solutions due to its low leakage, operational flexibility, and monolithic integration capability. Different from classical silicon-based devices, in-depth studies on the performances of nanoscale multi-gate transistors (e.g., a-InGaZnO-FET) are still barely conducted for physical description, due to the complicated multi-gating principle, finite-size effects on transport, increased variation sources and enlarged parasitic effect. …”
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Primary aldosteronism patients with previous cardiovascular and cerebrovascular events have high aldosterone responsiveness to ACTH stimulation by Eriko Nakano, Kosuke Mukai, Atsunori Fukuhara, Michio Otsuki, Iichiro Shimomura, Takamasa Ichijo, Mika Tsuiki, Norio Wada, Takashi Yoneda, Yoshiyu Takeda, Kenji Oki, Tetsuya Yamada, Yoshihiro Ogawa, Daisuke Yabe, Miki Kakutani, Masakatsu Sone, Takuyuki Katabami, Akiyo Tanabe, Mitsuhide Naruse, JPAS/JRAS Study Group

“…Logistic regression analysis demonstrated that the ΔPAC (the difference between the PAC measurements before and after ACTH stimulation) significantly increased the odds of previous CCV events in PA patients after adjusting for classical CCV event risk factors, baseline PAC and duration of hypertension (relative PAC: odds ratio [OR], 2.896; 95% confidence interval [CI], 0.989–8.482; ΔPAC: OR, 2.344; 95% CI, 1.149–4.780; ACTH-stimulated PAC: OR, 2.098; 95% CI, 0.694–6.339). …”
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Spatial Transmission Optimization for Secondary Users in Next-Gen Directional Networks by Zeinab Kteish, Jad Abou Chaaya, Abbass Nasser, Koffi-Clement Yao, Ali Mansour

“…This allows SU to exploit the spatial dimension in addition to the time-frequency dimensions, as in classical CR. However, sensing the beam of the PU and optimizing the transmission parameters of SU become crucial in this scenario to avoid interference between the SU and PU. …”
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Delayed Graft Function in Kidney Transplants: Time Evolution, Role of Acute Rejection, Risk Factors, and Impact on Patient and Graft Outcome by Martin Chaumont, Judith Racapé, Nilufer Broeders, Fadoua El Mountahi, Annick Massart, Thomas Baudoux, Jean-Michel Hougardy, Dimitri Mikhalsky, Anwar Hamade, Alain Le Moine, Daniel Abramowicz, Pierre Vereerstraeten

“…From 1983 to 2014, 1784 kidney-only transplantations from deceased donors were studied. Classical risk factors for DGF along with two novel ones, recipient’s perioperative saline loading and residual diuresis, were analyzed by logistic regression and receiver operating characteristic (ROC) curves. …”
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Ecological network construction and optimization of typical resource-based regions, and strategies for the enhancement of multiple ecosystem services: Balancing function and struct... by Shaoqing Wang, Yanling Zhao, Qiyuan Wang, He Ren, Shichao Zhu, Jiarui Cao

“…However, the application of the classic method of ENs construction in large-scale resource mining areas is not ideal. …”
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HMGB1 released from pyroptotic vascular endothelial cells promotes immune disorders in exertional heatstroke by Chaoping Yu, Yang Huang, Jiangang Xie, Chujun Duan, Shanshou Liu, Wei Zhao, Yutong Wang, Ran Zhuang, Junjie Li, Wen Yin

“…As high mobility group box 1 (HMGB1) is a prototypical alarmin that activates inflammatory and immune responses, this study aimed to investigate the effect and mechanism of HMGB1 in the pathogenesis of EHS.Methods Peripheral blood mononuclear cell (PBMC) transcriptome sequencing of healthy volunteers, classical heatstroke patients, and EHS patients was performed. …”
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Dynamic compressive characteristics of a green sandstone under coupled hydraulic-mechanical loading: Experiments and theoretical modeling by Bangbiao Wu, Geli Zhao, Ying Xu, Kaiwen Xia

“…Specifically, the dynamic compressive strength of GS exhibits an increase with higher loading rates and greater confining pressures, while it decreases with elevated pore pressure. Moreover, the classical Ashby-Sammis micromechanical model was augmented to account for dynamic loading and pore pressure considerations. …”
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Neethling Strain-Based Homologous Live Attenuated LSDV Vaccines Provide Protection Against Infection with a Clade 2.5 Recombinant LSDV Strain by Wannes Philips, Andy Haegeman, Nina Krešić, Laurent Mostin, Nick De Regge

“…Background: Vaccination is the main control measure to prevent Lumpy skin disease (LSD), and Neethling-based homologous vaccines have been shown to be safe and effective against infection with classical clade 1.2 strains. In 2017, recombinant clade 2 LSDV strains originating from a badly produced and insufficiently controlled vaccine were first detected in Russia. …”
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Transcriptional and Posttranscriptional Regulations of the HLA-G Gene by Erick C. Castelli, Luciana C. Veiga-Castelli, Layale Yaghi, Philippe Moreau, Eduardo A. Donadi

“…The HLA-G promoter region is different from the classical class I promoters, mainly because (i) it lacks regulatory responsive elements for IFN-γ and NF-κB, (ii) the proximal promoter region (within 200 bases from the first translated ATG) does not mediate transactivation by the principal HLA class I transactivation mechanisms, and (iii) the presence of identified alternative regulatory elements (heat shock, progesterone and hypoxia-responsive elements) and unidentified responsive elements for IL-10, glucocorticoids, and other transcription factors is evident. …”
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Allelic and epigenetic DNA variation in relation to F1 heterosis manifestation in F1 hybrids of Capsicum annuum L. by M. N. Shapturenko, S. V. Vakula, L. A. Tarutina, T. V. Nikitinskaya, T. V. Pechkovskaya, L. A. Mishin, L. V. Khotyleva

“…Managing F1 heterosis is one of the major objectives in hybrid crop breeding programs. The classical theory considers the heterozygosity in F1 hybrids to be the main factor contributing to heterosis and therefore presumes a linear relationship between the value of genetic polymorphisms in parental lines and the heterotic response of their F1 offspring. …”
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Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy by Sarala Raj Murthi, Andreas Petry, Bachuki Shashikadze, Jan B. Stöckl, Manuel Schmid, Gianluca Santamaria, Karin Klingel, Damir Kračun, Xinpei Chen, Sabine Bauer, Joachim P. Schmitt, Florian Flenkenthaler, Josh Gorham, Christopher N. Toepfer, David Potěšil, Pavel Hruška, Zbyněk Zdráhal, Zsuzsanna Mayer, Mathieu Klop, Luisa Lehmann, Yishi Qin, Laura Papanakli, Nadine Spielmann, Alessandra Moretti, Thomas Fröhlich, Peter Ewert, Stefan Holdenrieder, Jonathan G. Seidman, Christine E. Seidman, Agnes Görlach, Cordula M. Wolf

“…Therefore, the effect of a cardiomyocyte-specific Hif-1a knockout (cHif1aKO) was studied in an established α-MHC719/+ HCM mouse model that exhibits the classical features of human HCM. The results show that Hif-1α protein and HIF targets were upregulated in left ventricular tissue of α-MHC719/+ mice. …”
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Qualitative comparison of decalcifiers for mouse bone cryosections for subsequent biophotonic analysis by Shibarjun Mandal, Ramya Motganhalli Ravikumar, Astrid Tannert, Annett Urbanek, Rustam R. Guliev, Max Naumann, Sina M. Coldewey, Uta Dahmen, Lina Carvalho, Luís Bastião Silva, Ute Neugebauer

“…Our imaging analysis panel included classical histological staining (Hematoxylin and Eosin, H&E), immunofluorescence staining, and label-free Raman microspectroscopic imaging. …”
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