A three-dimensional mouse liver organoid platform for assessing EDCs metabolites simulating liver metabolism by Ji Hyun Moon, Hyun-Soo Roh, Young Jae Park, Hyun Ho Song, Jieun Choi, Da Woon Jung, Soo Jin Park, Ho Jin Park, So-Hyeon Park, Da-Eun Kim, Gahee Kim, Joong-Hyuck Auh, Dong Ha Bhang, Hong Jin Lee, Do Yup Lee

“…Organization for Economic Co-operation and Development (OECD) has advocated the development of in vitro assays that mimic in vivo hepatic metabolism to eventually replace classical animal tests. In response to this need, we established a 3D mouse liver organoid (mLO) platform that mimics the animal model and is distinct from existing models. …”
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Evaluating the Cassandra NoSQL Database Approach for Genomic Data Persistency by Rodrigo Aniceto, Rene Xavier, Valeria Guimarães, Fernanda Hondo, Maristela Holanda, Maria Emilia Walter, Sérgio Lifschitz

“…We also compare the results obtained with a classical relational database system and another NoSQL database approach, MongoDB.…”
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Bayesian and Frequentist Estimation of Stress-Strength Reliability from a New Extended Burr XII Distribution by Varun Agiwal, Shikhar Tyagi, Christophe Chesneau

“…We examine its quantile function, stochastic dominance, ordinary moments, weighted moments, incomplete moments, and stress-strength reliability cofficient. Then, the classical and Bayesian approaches are developed to estimate the model and stress strength reliability parameters. …”
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PhyICNet: Physics-informed interactive learning convolutional recurrent network for spatiotemporal dynamics by Ruohan Cao, Jin Su, Jinqian Feng, Qin Guo

“…Numerical experiments on four kinds of classical spatiotemporal PDEs tasks show that the extended models have superiority in accuracy, long-range learning ability, and robustness. …”
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De Quervain’s Tenosynovitis Virally Exacerbated by SARS-CoV-2 and Influenza Infections: A Case Report by Maria Gergoudis, Logan Laubach, Glenn E. Lee, Jeffrey R. Donowitz

“…The etiology of De Quervain’s tenosynovitis remains unclear. It has classically been categorized as a noninflammatory degenerative process, but recent evidence suggests a possible inflammatory connection. …”
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Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage by Jinyao Shi, Zhouqiao Wu, Ziyu Li, Jiafu Ji

“…Macrophages are characterized by high heterogeneity, which can polarize into at least two major extremes, M1-type macrophages (classical activation) which are normally derived from monocytes and M2-type macrophages (alternative activation) which are mostly those tissue-resident macrophages. …”
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Development of an MPS Code for Corium Behavior Analysis: 3D Alloy Melting by Lijun Jian, Peng Yu, Jie Pei, Xiao Zeng, Yidan Yuan

“…Validation of the developed simulation approach is carried out on a classical water column collapse example. The development of the heat transfer model is validated by the example of a one-dimensional semi-infinite plate. …”
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Fatigue of SFRC in compression: Size effect & autogenous self-healing by G. Ruiz, Á. de la Rosa, J. J. Ortega, E. Poveda, R. C. Yu, M. Tarifa, X.X. Zhang, Lucía Garijo

“…The review demonstrates that larger SFRC specimens have reduced fatigue lives, attributed to increased elastic energy driving microcrack growth, aligning with classical size effect theory. Additionally, it highlights autogenous self-healing, where fatigue-induced microcracks release occluded water, promoting rehydration and calcium carbonate precipitation, which enhances residual strength. …”
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Creation of Reliable Relevance Judgments in Information Retrieval Systems Evaluation Experimentation through Crowdsourcing: A Review by Parnia Samimi, Sri Devi Ravana

“…Test collection is used to evaluate the information retrieval systems in laboratory-based evaluation experimentation. In a classic setting, generating relevance judgments involves human assessors and is a costly and time consuming task. …”
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The application of emerging technologies for the quality and safety evaluation of oilseeds and edible oils by Xue Li, Wenwen Liu, Lu Xiao, Jie Zhao, Yan Chen, Liangxiao Zhang, Peiwu Li, Dolores Pérez-Marín, Xu Wang

“…Safety and quality of oilseeds and edible oils cannot be ignored, which can pose risk to human health and cause agro-economic loss. Classical techniques widely used to detect the safety and quality attributes of oilseeds and edible oils often involve time-consuming and tedious operation; therefore, the development of low cost, rapid and non-destructive detection method is necessary. …”
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Application of artificial intelligence in ophthalmology for solving the problem of semantic segmentation of fundus images by N.S. Demin, N.Y. Ilyasova, R.A. Paringer, D.V. Kirsh

“…The paper presents main aspects of the application of artificial intelligence in ophthalmology for the diagnosis and treatment of eye diseases, considering the problem of semantic segmentation of fundus images as an example. The classic approach to semantic segmentation on the basis of textural features is compared to the proposed approach based on neural networks. …”
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Analytical Solutions of a Space-Time Fractional Derivative of Groundwater Flow Equation by Abdon Atangana, P. D. Vermeulen

“…The classical Darcy law is generalized by regarding the water flow as a function of a noninteger order derivative of the piezometric head. …”
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Novel design of drug delivery in stented arteries:A numerical comparative study by Mario Grassi, Giuseppe Pontrelli, Luciano Teresi, Gabriele Grassi, Lorenzo Comel, Alessio Ferluga, Luigi Galasso

“…Implantation of drug eluting stents following percutaneoustransluminal angioplasty has revealed a well establishedtechnique for treating occlusions caused bythe atherosclerotic plaque.However, due to the risk of vascular re-occlusion,other alternative therapeutic strategiesof drug delivery are currently being investigated.Polymeric endoluminal pave stenting is an emerging technologyfor preventing blood erosion and for optimizing drug release.The classical and novel methodologies are compared througha mathematical model able to predict the evolution ofthe drug concentration in a cross-section of the wall.Though limited to an idealized configuration, the presentmodel is shown to catch most of the relevant aspects ofthe drug dynamics in a delivery system.Results of numerical simulations shows that a bi-layer gel paved stenting guarantees a uniform drug elution anda prolonged perfusionof the tissues, and remains a promising and effective techniquein drug delivery.…”
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Do gender stereotypes bias the processing of morphological innovations? The case of gender-inclusive language in Spanish by Stetie Noelia Ayelén, Zunino Gabriela Mariel

“…Classical grammatical studies in Spanish only consider binary gender and claim that gender assignment is an arbitrary process. …”
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Leprosy with Atypical Skin Lesions Masquerading as Relapsing Polychondritis by Punit Pruthi, Hariharan Munganda, Amit Bangia, Uma Rani, Rajesh Budhiraja, Swapnil Brajpuriya

“…Histopathology confirmed the diagnosis, although the ear and skin lesions were not classical of leprosy. Such a presentation of leprosy closely mimicking relapsing polychondritis has not been described previously. …”
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An Improved Unscented Kalman Filter Algorithm for Radar Azimuth Mutation by Dazhang You, Pan Liu, Wei Shang, Yepeng Zhang, Yawei Kang, Jun Xiong

“…Furthermore, several simulation results show that the SVD-MUKF algorithm proposed in this paper is better than the SVD-UKF (Singular Value Decomposition of Unscented Kalman Filter) algorithm and classical UKF algorithm in accuracy and stability. …”
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Numerical Study on Resistance Change Characteristics of Phase Change Materials by Yifang Su, Yihang Zhang, Kaifeng Lin, Guanjun Zhao, Qinzheng Yu, Zuoqi Hu, Xiongfei Tao

“…To study the characteristics of the phase change materials, a numerical simulation model of the resistive change unit based on the finite element method and the classic nucleation/growth theory is established, while the partial differential equations of electricity and heat conduction and the discrete formula of the finite element are also derived. …”
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Solving a Vehicle Routing Problem under Uncertainty by a Differential Evolution Algorithm by Alireza Salamatbakhsh, Reza Tavakkoli-Moghaddam, Ali Pahlevani

“…Methodology: It is proven that classic models in vehicle routing problems (VRPs) belong to the class of NP-hard ones; thus, due to its complexity using exact methods in large-scale problems, a meta-heuristic-based differential evolution (DE) algorithm is proposed. …”
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The Influence of Corporate Philanthropy and Risk Management on Corporate Value by Suwarno Suwarno, Siti Mujanah, Abdul Halik

“…Utilizing a sample of 112 manufacturing companies listed on the Indonesia Stock Exchange for the 2022 period, this research employs regression analysis, preceded by classical assumption tests to ensure the validity and reliability of the data. …”
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Triplet-ground-state nonalternant nanographene with high stability and long spin lifetimes by Weixiang Zhou, Yiyang Fei, Yu-Shuang Zhang, Xiaohe Miao, Shang-Da Jiang, Junzhi Liu

“…Here, we report a straightforward synthetic and isolation method for synthesizing a nonalternant nanographene (1) with a triplet ground state. Moving beyond the classic m-xylylene scaffold for high-spin organic molecules, seven-five-seven (7–5–7)-membered rings are introduced to create stable high-spin diradicals with half-lives (t 1/2) as long as 101 days. …”
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