Nonhomologous DNA End Joining in Cell-Free Extracts by Sheetal Sharma, Sathees C. Raghavan

“…Among various DNA damages, double-strand breaks (DSBs) are considered as most deleterious, as they may lead to chromosomal rearrangements and cancer when unrepaired. …”
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CTCF, Cohesin, and Chromatin in Human Cancer by Sang-Hyun Song, Tae-You Kim

“…Such spatial genomic organization is functionally important for the spatial disposition of chromosomes to control cell fate during development and differentiation. …”
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Pattern and risk factors of congenital anomalies among children attending Specialized Hospitals in Sohag Governorate by Ayman S. Abd El-Hady, Abdel-Nasser S. Mohammed, Mohammed A. Aladawy, Gamal E. Soliman

“…Results The study revealed that Cardiac malformations came first by (26.6%) mostly as cardiac septal defects (15.3%), Chromosomal defects came second by (22%), Neural tube defects (12%) Oral cleft defects (10.6%), Genitourinary defects (8.6%) and Digestive system anomalies by (4.6%). …”
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The role of SAGA in the transcription and export of mRNA by E. N. Nabirochkina, M. M. Kurshakova, S. G. Georgieva, D. V. Kopytova

“…Immunostaining of the polytene chromosomes of Drosophila larvae revealed that Sgf11 is present at the sites of localization of snRNA genes. …”
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Prenatal Cytogenetic Diagnosis in Cienfuegos: Years 2007-2018 by Pedro Alí Díaz-Véliz Jiménez, Belkis Vidal Hernández, Teresa Velázquez Martínez, Yoelkis Sanjurjo Pérez, Iliana González Santana

“…<strong><br />Results:</strong> 3260 cytogenetic prenatal diagnoses were determined during the study period, 83 of them presented chromosomal alterations, for 2,6 % positivity. Only 33,7 % of positive cases and healthy carriers are under 37 years old. …”
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THE REORGANIZATION OF PLANT GENOMES DURING ALLOPOLYPLOIDISATION by A. B. Shcherban

“…The data on various genomic changes at early stages of allopolyploidization, including activation of mobile elements, chromosomal rearrangements, epigenetic and transcriptomic changes, etc., are summarized. …”
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Dynamic Analysis of DNA Damage by Flow Cytometry and FISH by Demetrios P. Matthopoulos

“…Flow-sorting induced micronuclei, based on their DNA content, in combination with chromosomal FISH and other molecular techniques, may provide information on these events.…”
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Prenatal Diagnosis of Complete Atrioventricular Septal Defect: Perinatal and Neonatal Outcomes by Gokhan Yıldırım, Kemal Gungorduk, Fehmi Yazıcıoğlu, Ahmet Gul, Fatma Çakar, Özgü Çelikkol, Yavuz Ceylan

“…AVSD is associated with chromosomal, other cardiac, and extracardiac abnormalities. …”
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KRAS, p53 and BRAF Gene Mutations and Aneuploidy in Sporadic Colorectal Cancer Progression by Daniele Calistri, Claudia Rengucci, Ian Seymour, Elena Leonardi, Mauro Truini, Davide Malacarne, Patrizio Castagnola, Walter Giaretti

“…Background: The origin and mechanisms of chromosomal instability are still widely unknown. We previously investigated a limited number of human sporadic colorectal cancers (CRCs) and observed a statistically different occurrence of KRAS and p53 mutations among predetermined subgroups of tumors with different degrees of DNA aneuploidy. …”
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LATE BLIGHT RESISTANCE OF HYBRIDS OBTAINED IN CROSSES OF <i> SOLANUM TUBEROSUM </i> L. WITH THE BOLIVIAN DIPLOID POTATO SPECIES by N. M. Zoteyeva, Yu. I. Karabitsina

“…S. berthaultii possesses a triploid number of chromosomes (2n = 36) and is completely sterile. Pollen grains of S. ruiz-ceballosii hybrid are partially fertile.…”
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Traces of archaic mitochondrial lineages persist in Austronesian-speaking Formosan populations. by Jean A Trejaut, Toomas Kivisild, Jun Hun Loo, Chien Liang Lee, Chun Lin He, Chia Jung Hsu, Zheng Yan Lee, Marie Lin

“…Considering the lack of a common specific Y chromosomal element shared by the Taiwanese aboriginals and Polynesians, the mtDNA evidence provided here is also consistent with the suggestion that the proto-Oceanic societies would have been mainly matrilocal.…”
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Genome-wide identification of high-affinity nitrate transporter 2 (NRT2) gene family under phytohormones and abiotic stresses in alfalfa (Medicago sativa) by Yanyan Luo, Lili Nan

“…They were named MsNRT2.1-2.3 based on their chromosomal location. The phylogenetic tree revealed that NRT2 proteins were categorized into two main subgroups, which were further confirmed by their gene structure and conserved motifs. …”
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Fast and accurate imputation of genotypes from noisy low-coverage sequencing data in bi-parental populations. by Cécile Triay, Alice Boizet, Christopher Fragoso, Anestis Gkanogiannis, Jean-François Rami, Mathias Lorieux

“…Here, we present a new algorithm for imputation of LC-NGS data that eliminates the need of complex pre-filtering of noisy data, accurately types heterozygous chromosomal regions, precisely estimates crossover positions, corrects erroneous data, and imputes missing data. …”
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Genome-Wide Identification and Expression Analysis of Amino Acid/Auxin Permease (AAAP) Genes in Grapes (<i>Vitis vinifera</i> L.) Under Abiotic Stress and During Development by Xufeng Guo, Na He, Biying Huang, Chongyao Chen, Yanxia Zhang, Xiaoyu Yang, Jie Li, Zhigang Dong

“…Consequently, we conducted a comprehensive bioinformatics analysis of all <i>AAAP</i> genes in grapes, encompassing genome sequence analysis, conserved protein domain identification, chromosomal localization, phylogenetic relationship analysis, and gene expression profiling. …”
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Identification and characterization of soybean phytochrome-interacting factors and their potential roles in abiotic stress by Dewei Mu, Zhaowei Shui, Haoyu Guo, Hengke Jiang, Yuhan Liu, Liqiu Luo, Yanpeng Zhang, Xinxin Zhang, Jiaxin Yu, Shulin Liao, Liang Yu, Chunyan Liu, Junbo Du

“…These are unevenly distributed on 12 soybean chromosomes. The analysis of gene duplication events revealed the existence of five pairs of duplicated genes within the GmPIF gene set. …”
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Synchronous clonally related anaplastic large cell lymphoma and malignant histiocytosis by Mirvate Harb, Tom Abrassart, Laurent Dewispeleare, Pierre Sidon, Natacha Dirckx, Anne-laure Trepant, Julie Castiaux, Pierre Heimann, Jean-Francois Emile, Hussein Farhat

“…However, these two cells populations shared common chromosomal abnormalities. First line treatment protocol included Brentuximab vedotin, cyclophosphamide, doxorubicin, and methylprednisolone. …”
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An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma by Michele Massimino, Elena Tirrò, Stefania Stella, Cristina Tomarchio, Sebastiano Di Bella, Silvia Rita Vitale, Chiara Conti, Marialuisa Puglisi, Rosa Maria Di Crescenzo, Silvia Varricchio, Francesco Merolla, Giuseppe Broggi, Federica Martorana, Alice Turdo, Miriam Gaggianesi, Livia Manzella, Andrea Russo, Giorgio Stassi, Rosario Caltabiano, Stefania Staibano, Paolo Vigneri

“…Methods: Following the findings published by “The Cancer Genome Atlas–UM” (TCGA-UM) study, we developed an NGS-based gene panel (called the UMpanel) that classifies mutation sets in four categories: initiating alterations (<i>CYSLTR2</i>, <i>GNA11</i>, <i>GNAQ</i> and <i>PLCB4</i>), prognostic alterations (<i>BAP1</i>, <i>EIF1AX</i>, <i>SF3B1</i> and <i>SRSF2</i>), emergent biomarkers (<i>CDKN2A</i>, <i>CENPE</i>, <i>FOXO1</i>, <i>HIF1A</i>, <i>RPL5</i> and <i>TP53</i>) and chromosomal abnormalities (imbalances in chromosomes 1, 3 and 8). …”
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Application of copy number variation sequencing combined with whole exome sequencing in prenatal left–right asymmetry disorders by Yu Qin, Muon Senglong, Koksear Touch, Juan Xiao, Ruijie Fang, Qingling kang, Lei Fan, Shufang Li, Jing Liu, Jianli Wu, Yuanyuan Wu, Xinwei Shi, Haiyi Liu, Xun Gong, Xingguang Lin, Ling Feng, Suhua Chen, Wei Li

“…This study aims to explore the genetic underpinnings of chromosomal variants and individual genes in fetuses afflicted with prenatal LR asymmetry disorder. …”
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Pathobiology of Anaplastic Large Cell Lymphoma by Pier Paolo Piccaluga, Anna Gazzola, Claudia Mannu, Claudio Agostinelli, Francesco Bacci, Elena Sabattini, Carlo Sagramoso, Roberto Piva, Fernando Roncolato, Giorgio Inghirami, Stefano A. Pileri

“…The phenotype is reported in detail: the expression of the ALK protein as well as the chromosomal abnormalities is discussed with their potential pathogenetic implications. …”
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SEGREGATION MODELS OF COMPLEX QUANTITATIVE TRAITS AND LINKAGE ANALYSIS IN EXTENDED RECOMBINANT INBRED CROSSES by M. S. Diakov, A. V. Osadchuk

“…Then linkage analysis is performed: model loci positions of the found solutions are mapped on chromosomes. The search procedure and linkage analysis have been tested with real data on cerebellum weight in laboratory mice as a quantitative trait. …”
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