An Efficient Genome Fragment Assembling Using GA with Neighborhood Aware Fitness Function by Satoko Kikuchi, Goutam Chakraborty

“…In the proposed GA, the length of the chromosome, which represents the volume of the search space, is reduced with advancing generations, and thereby improves search efficiency. …”
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Antioxidant Functions of Nitric Oxide Synthase in a Methicillin Sensitive Staphylococcus aureus by Manisha Vaish, Vineet K. Singh

“…However certain Gram positive bacteria including Staphylococcus aureus possess a gene encoding nitric oxide synthase (SaNOS) in their chromosome. In this study it was determined that under normal growth conditions, expression of SaNOS was highest during early exponential phase of the bacterial growth. …”
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Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever by Yunus Ugan, Atalay Doğru, Hüseyin Şencan, Mehmet Şahin, Şevket Ercan Tunç

“…The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. While more than 310 sequence variants in the MEFV gene have been described to date, the diagnosis is still established clinically. …”
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A Case of Clitoral Hypertrophy of Unknown Origin by Tetsuya Okaneya, Kiyoshi Onishi, Michio Saze, Kei Iwakura, Hiroko Sakuma

“…Various tests were performed. Sex chromosome or hormonal abnormalities and tumorous lesions were not detected, and the ovaries, uterus, and vagina were normal, indicating that disorders of mullerian development were negative. …”
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HbS-Sicilian (δβ)0-Thalassemia: A Rare Variant of Sickle Cell by Grace Onimoe, Genine Smarzo

“…Sickle cell disease (SCD) is caused by a mutation in the sixth codon of the β-globin gene on chromosome 11, which leads to a single amino acid substitution (glutamine to valine). …”
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Trichoscopy in Unveiling the Triad of Netherton Syndrome by H Bangaru, D Ashwini

“…Netherton syndrome (NS) is a rare autosomal recessive disorder characterized by the triad of congenital ichthyosiform erythroderma or ichthyosis linearis circumflexa (ILC), hair shaft abnormalities, and atopic diathesis (elevated serum IgE) caused by mutations in serine protease-inhibitor (SPINK5) gene located on chromosome 5q31–32. Here, we present a case of a 16-year-old female born to second-degree consanguineous marriage who presented with a history of atopy, generalized xerosis, plaques with serpiginous borders, and double-edged scales over the trunk, upper and lower limbs, lichenification in flexures, sparse eyelashes, and eyebrows predominantly over lateral half was noted. …”
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Cloning a Chloroplast Genome in Saccharomyces cerevisiae and Escherichia coli by Emma Walker, Bogumil Karas

“…Prior to our work, the chloroplast genomes of Chlamydomonas reinhardtii (204 kb) and Zea mays (140 kb) had been cloned using bacterial and yeast artificial chromosome (BAC/YAC) libraries, respectively. These methods lack design flexibility as they are reliant upon the random capture of genomic fragments during BAC/YAC library creation; additionally, both demonstrated a low efficiency (≤ 10%) for correct assembly of the genome in yeast. …”
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Repeated Long-Term DT Application in the DEREG Mouse Induces a Neutralizing Anti-DT Antibody Response by Junhua Wang, Myriam Siffert, Markus Spiliotis, Bruno Gottstein

“…Genetic tools exploiting the foxp3 locus including bacterial artificial chromosome- (BAC-) transgenic DEpletion of REGulatory T cells (DEREG) mice have provided essential information on Treg biology and the potential therapeutic modulation of tolerance. …”
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Plant Regeneration and Cellular Behaviour Studies in Celosia cristata Grown In Vivo and In Vitro by Rosna Mat Taha, Sharifah Nurashikin Wafa

“…It was observed that Mitotic Index (MI), mean chromosome numbers, and mean nuclear to cell area ratio of in vitro root meristem cells were slightly higher compared to in vivo values. …”
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Some Effective Tight-Binding Models for Electrons in DNA Conduction: A Review by Hiroaki Yamada, Kazumoto Iguchi

“…In addition, we investigated the localization properties of electronic states in several actual DNA sequences such as bacteriophages of Escherichia coli, human-chromosome 22, compared with those of the artificial disordered sequences with correlation. …”
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Iron-regulatory liver hormone hepcidin and its place in the system of congenital immunity by O. A. Smirnov

“…Hepcidin is coded by HAMP gene (Hepcidin Antimicrobial Peptide) in chromosome 19. Expression peptide mRNA in hepatocytes is induced by proinflammatory cytokines (IL-1α, IL-6 and TNF-α) similar to acute phase proteins of inflammation, and also by liver iron overload. …”
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Meiosis-specific stable binding of augmin to acentrosomal spindle poles promotes biased microtubule assembly in oocytes. by Nathalie Colombié, A Agata Głuszek, Ana M Meireles, Hiroyuki Ohkura

“…The level of Augmin accumulated at spindle poles is well correlated with the degree of chromosome congression. Fluorescence recovery after photobleaching shows that Augmin stably associates with the polar regions of the spindle in oocytes, unlike in mitotic cells where it transiently and uniformly associates with the metaphase spindle. …”
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A Three-Generation Family with Idiopathic Facial Palsy Suggesting an Autosomal Dominant Inheritance with High Penetrance by Christian Grønhøj Larsen, Mette Gyldenløve, Aia Elise Jønch, Birgitte Charabi, Zeynep Tümer

“…The mode of inheritance of IFP has previously been suggested as autosomal dominant with low or variable penetrance, but the present family indicates an autosomal dominant trait with high or complete penetrance. Chromosome microarray studies did not reveal a pathogenic copy number variation, which could enable identification of a candidate gene.…”
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Severe Short Stature in an Adolescent Male with Prader-Willi Syndrome and Congenital Adrenal Hyperplasia: A Therapeutic Conundrum by Meredith Wasserman, Erin M. Mulvihill, Angela Ganan-Soto, Serife Uysal, Jose Bernardo Quintos

“…Prader-Willi syndrome (PWS) is a genetic disorder resulting from a defect on chromosome 15 due to paternal deletion, maternal uniparental disomy, or imprinting defect. …”
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Genome Sequence of Colistin-Resistant Bacteremic Shewanella algae Carrying the Beta-Lactamase Gene blaOXA-55 by Ying-Ju Chen, Kwong-Chung Tung, Yu-Kai Hong, Shi-Yu Chen, Yao-Ting Huang, Po-Yu Liu

“…Here, we report the results of the whole-genome sequencing of colistin-resistant S. algae TYL, a blood isolate. Chromosome-encoded pmrC associated with colistin resistance and blaOXA-55 gene intrinsic to S. algae was identified. …”
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Glycated Serum Protein Genetics and Pleiotropy with Cardiometabolic Risk Factors by Matthew P. Johnson, Ryan Keyho, Nicholas B. Blackburn, Sandra Laston, Satish Kumar, Juan Peralta, Suman S. Thapa, Bradford Towne, Janardan Subedi, John Blangero, Sarah Williams-Blangero

“…We localized a significant (LOD score=3.18) and novel GSP QTL on chromosome 11q, which has been previously linked to type 2 diabetes. …”
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Clinical And Molecular-Genetic Features Of Congenital Aniridia by T.A. Vasilieva, Voskresenskaya A. A, V.V. Kadyshev, N.A. Pozdeeva, A.V. Marakhonov, R.A. Zinchenko

“…<br> <br> <b>Key words:</b> congenital aniridia, PAX6 mutations, chromosome region 11p13 deletions, relationships between mutation type and clinical trait.…”
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ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics. by Michael D Stubenvoll, Jeffrey C Medley, Miranda Irwin, Mi Hye Song

“…As cells progress to mitosis, centrosomes recruit more microtubules (MT) to form mitotic bipolar spindles that ensure proper chromosome segregation. We report a new role for ATX-2, a C. elegans ortholog of Human Ataxin-2, in regulating centrosome size and MT dynamics. …”
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Charcot-Marie-Tooth disease and dilated cardiomyopathy. A rare combination. by Rafael Pila Pérez, Víctor Adolfo Holguín Prieto, Leandro Segura Pujol

“…Approximately 60% of patients who suffer from it carry chromosome 17 duplication, which is why it has been considered very appropriate to convey the experience of this case.…”
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Expression of Four Methionine Sulfoxide Reductases in Staphylococcus aureus by Kuldeep Singh, Vineet K. Singh

“…To determine the expression pattern of msr genes, three independent reporter strains were constructed where msr promoter was cloned in front of a promoterless lacZ and the resulting construct was integrated in the chromosome. Using these strains, it was determined that the msrA1/B expression is significantly higher in S. aureus compared to msrA2 or msrA3. …”
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