Dissecting the genetic architecture of sunflower disc diameter using genome‐wide association study by Yavuz Delen, Ravi V. Mural, Semra Palali‐Delen, Gen Xu, James C. Schnable, Ismail Dweikat, Jinliang Yang

“…The MLM analysis identified two significant peaks: a prominent signal on chromosome 10 and a relatively weaker signal on chromosome 16, both of which were also detected by farmCPU. …”
Get full text

The widely used Ucp1-Cre transgene elicits complex developmental and metabolic phenotypes by Manasi Suchit Halurkar, Oto Inoue, Archana Singh, Rajib Mukherjee, Meghana Ginugu, Christopher Ahn, Christian Louis Bonatto Paese, Molly Duszynski, Samantha A. Brugmann, Hee-Woong Lim, Joan Sanchez-Gurmaches

“…Abstract Bacterial artificial chromosome transgenic models, including most Cre-recombinases, enable potent interrogation of gene function in vivo but require rigorous validation as limitations emerge. …”
Get full text

Solving degree-constrained multicast routing problem by a heuristic genetic algorithm by PAN Yun1, WANG Xing-gang2, FENG Yan-li3, YU Zhen-wei4

“…With the purpose to solve the degree constrained multicast routing model efficiently,the evolutionary strategy was introduced into heuristic search methods by employing the chromosome as the heuristic information for global searching,and then a hybrid genetic algorithm was proposed.The algorithm not only avoids the difficulty of coding for multicast trees,but also possesses fast convergency and global optimizing capability.Meanwhile,the efficiency of the method is supported by a great number of numerical experiments.…”
Get full text

YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database by Mengge Wang, Shuhan Duan, Qiuxia Sun, Kaijun Liu, Yan Liu, Zhiyong Wang, Xiangping Li, Lanhai Wei, Yunhui Liu, Shengjie Nie, Kun Zhou, 10K_CPGDP consortium, Yongxin Ma, Huijun Yuan, Bing Liu, Lan Hu, Chao Liu, Guanglin He

“…Conclusions This work successfully integrated Y-chromosome-related basic genomic science with forensic and anthropological translational applications, emphasizing the necessity of comprehensively characterizing Y-chromosome genomic diversity from genomically under-representative populations. …”
Get full text

Telomere DNA in the insect order Dermaptera and the first evidence for the non-canonical telomeric motif TTCGG in Arthropoda by Vladimir A. Lukhtanov

“…In this study, analysis of the chromosome-level genome assembly shows that the telomeric DNA of the earwig Labia minor (Linnaeus, 1758) (Polyneoptera, Dermaptera, Spongiphoridae) consists of repeats of the 5 bp motif TTCGG/CCGAA. …”
Get full text

FHIT Doubts are Clear Now by Anjilna Wali

“…The fragile histidine triad (FHIT) gene is a bonafide tumor-suppressor gene present on the short arm of chromosome 3 and its loss of function has been evaluated in different types of cancers. …”
Get full text

Sex-biased gene expression across tissues reveals unexpected differentiation in the gills of the threespine stickleback by Sylvestre, Florent, Aubin-Horth, Nadia, Bernatchez, Louis

“…Sexual dimorphism can evolve through sex-specific regulation of the same gene set. However, sex chromosomes can also facilitate this by directly linking gene expression to sex. …”
Get full text

The interphase period “germination–heading” of 8x and 6x triticale with different dominant Vrn genes by P. I. Stepochkin, A. I. Stasyuk

“…It means that the genetic material from the chromosome of the fifth homeologous group of the D genome of the bread wheat is included in the plant genotypes. …”
Get full text

The consensus rye microsatellite map with EST-SSRs transferred from wheat by D. O. Vidakovic, D. Perovic, T. V. Semilet, A. Börner, E. K. Khlestkina

“…Broadening the list of available SSRs in rye mapped to chromosomes is still needed, since some rye chromosome maps still have just a few microsatellite loci mapped. …”
Get full text

Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting by Ming Liu, Li Zheng, Yang Zhang, Jinhui Tian

“…PA is involved in processes such as nuclear division, chromosome segregation, mitotic nuclear division, condensed chromosome formation, and protein C-terminus binding. …”
Get full text

Plasmid-free production of the plant lignan pinoresinol in growing Escherichia coli cells by U. Joost Luelf, Alexander Wassing, Lisa M. Böhmer, Vlada B. Urlacher

“…To this end, a simple and versatile plasmid toolbox for CRISPR/Cas9-assisted chromosomal integration has been developed, which allows the easy transfer of genes from the pET vector series into the E. coli chromosome. …”
Get full text

Transient Neonatal Diabetes Mellitus with the Rare Association of Nonsuppurative Sialadenitis and Genetic Defects in 6q24 by Manal Mustafa, Nitin Ramdas, Mahmoud Elhalik, Arif Faquih

“…Genetic analysis revealed multiple loci hypomethylation of the PLAGL1/HYMAI-DMR in the TNDM region in chromosome 6q24 and two pathogenic heterozygous variants in the ZFP57 gene. …”
Get full text

Efficiency to Discovery Transgenic Loci in GM Rice Using Next Generation Sequencing Whole Genome Re-sequencing by Doori Park, Dongin Kim, Green Jang, Jongsung Lim, Yun-Ji Shin, Jina Kim, Mi-Seong Seo, Su-Hyun Park, Ju-Kon Kim, Tae-Ho Kwon, Ik-Young Choi

“…The EGF transgenic site was confirmed only on chromosome 4 by PCR. Results of this study demonstrated the success of NGS data to characterize the rice genome. …”
Get full text

Williams Syndrome with a “Twist” by Despoina Maritsi, Lydia Kossiva, George Vartzelis

“…Williams syndrome is a rare genetic condition with multisystemic involvement, caused by a microscopic deletion in the chromosome band 7q11.23. We describe the first case of a toddler with Williams syndrome who developed Benign Paroxysmal Torticollis (BPT), a benign dystonic disorder of unknown aetiology.…”
Get full text

NATURAL MUTAGENESIS AS A POSSIBLE CAUSAL FACTOR FOR OCCURRENCE OF OBLIGATE EMBRYONIC DIAPAUSE IN MAMMALS (A HYPOTHESIS) by G. K. Isakova

“…Available data of cytogenetics, embryology, evolutionary morphology, and evolutionary ecology allow to believe that the obligatory stage of embryonic diapause might occur in single individuals with indifferent taxonomic groups in consequence of chromosome mutation caused by alteration in the environment and affected the expression of genes controlling the timing of embryogenesis.…”
Get full text

Whole-genome analysis of a ST45-SCCmec IVa (2B)-t116 methicillin-resistant Staphylococcus aureus strain isolated from the sputum of a 5-year-old child with pneumonia by Lin Huang, Rui Guo, Jingxian Lin, Xiaowei Li, Zhicong Li, Limei Zhang, Wenting Li, Rui Xue, Cheng Zhang, Xiaosan Feng, Xiaobin Li, Xiaobin Li

“…Besides mecA, another beta-lactam resistance gene blaZ was found to located on six copies of bla complex (blaZ, blaR1, and blaI) on the chromosome of SA2107. Three kinds of virulence factors were detected on the chromosome of SA2107, including genes encoding toxins, exoenzyme, and immune-modulating protein. …”
Get full text

Genome-Wide Identification of miRNAs in Oily Persimmon (<i>Diospyros oleifera</i> Cheng) and Their Functional Targets Associated with Proanthocyanidin Metabolism by Meng Zhang, Rong Wu, Xinlong Hu, Zhengrong Luo, Qinglin Zhang, Sichao Yang

“…In our study, we identified genome-wide microRNAs (miRNAs) and their precursor sequence based on the chromosome-scale genome of oily persimmon and the miRNA database of “Eshi 1” according to the sequence alignment and secondary structure accession. …”
Get full text

Investigation of Association with First-Trimester Free Human Chorionic Gonadotropin-ß, Pregnancy - Associated Plasma Protein-A, and Adverse Pregnancy Outcomes by Gokhan Gonen, Yasam Kemal Akpak, Murat Muhcu

“…Patients with multiple pregnancies, chromosome aberrations, or fetal anomalies were excluded. …”
Get full text

Detection of genomic loci associated with days to heading in tropical japonica rice through QTL-seq by Khairul Yusuf Nasution, Dani Satyawan, Muhamad Yunus, Azri Kusuma Dewi, Puput Melati, Marina Yuniawati Maryono, Ita Dwimahyani, Wening Enggarini, Sobrizal

“…Whole genome sequencing (WGS) derived single nucleotide polymorphism (SNP) from early and late-heading bulks were used to identify three candidate regions with strong association to DTH: qDTH3.1 and qDTH3.2 on chromosome 3, and qDTH7.1 on chromosome 7, with the latter linked to the Oryza sativa Pseudo-Response Regulator 37 (OsPRR37) gene. …”
Get full text

Cytogenetics and Molecular Abnormalities in Pediatric Patients with Acute Myeloid Leukemia in a Referral Center in Tehran, Iran by Mahshid Heidary Sadegh, Maniya Mozafari, Mohammad Vasei, Sajjadeh Movahedinia, Marzieh Hosseini, Moeinadin Safavi

“…Monosomy 7/del(7q) and chromosome 11 alteration were the most common cytogenetic abnormalities. …”
Get full text