The Role of SUMO1 Modification of SOX9 in Cartilage Development Stimulated by Zinc Ions in Mice by Na Xue, Jing Zhao, Jing Yin, Liang Liu, Zhong Yang, Shuchao Zhai, Xiyun Bian, Xiang Gao

“…Furthermore, ATDC5 murine chondrocytes were subjected to treatment with ZnCl2, followed by RT-PCR assessment to scrutinize the expression levels of MMP13, Collagen II, RUNX2, and aggrecan. …”
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Mesenchymal stem cells for osteoarthritis: Recent advances in related cell therapy by Jianjing Lin, Jingtao Huang, Zilu Jiao, Mengyuan Nian, Canfeng Li, Yali Dai, Shicheng Jia, Xintao Zhang

“…Mesenchymal stem cells from various tissues are the most studied cell type and have been used in preclinical and clinical studies of OA, because they are more widely available, have a greater capacity for in vitro expansion, and have anti‐inflammatory and immunomodulatory properties compared to autologous chondrocytes. This article will systematically review the latest developments in these areas. …”
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A Case of Osteochondroma in a Cat's Ear by Eren Polat, Burak Karabulut, Elif Ekinci

“…Microscopic examination of the mass revealed that there were chondrocytes among the dense bone cell accumulations and that they formed islands in some areas. …”
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Discoidin domain receptors; an ancient family of collagen receptors has major roles in bone development, regeneration and metabolism by Renny T. Franceschi, Shawn A. Hallett, Chunxi Ge

“…The extracellular matrix (ECM) niche plays a critical role in determining cellular behavior during bone development including the differentiation and lineage allocation of skeletal progenitor cells to chondrocytes, osteoblasts, or marrow adipocytes. As the major ECM component in mineralized tissues, collagen has instructive as well as structural roles during bone development and is required for bone cell differentiation. …”
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Nanoparticles Containing Hyaluronan Acid and Astragalus Polysaccharides for Treating Osteoarthritis by Gongbiao Lu, Lin Du, Jishou Lu, Liuzhong Jin

“…Our results demonstrated that nano treatment significantly improved IL-1β-induced cell viability of chondrocytes. Induction of MMP-9, MMP-13, and TNF-α was alleviated by nanoparticles. …”
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Mesenchymal Stem Cells Isolated from Adipose and Other Tissues: Basic Biological Properties and Clinical Applications by Hakan Orbay, Morikuni Tobita, Hiroshi Mizuno

“…MSCs are capable of differentiating into multiple cell types including adipocytes, chondrocytes, osteocytes, and cardiomyocytes. Isolation and induction of these cells could provide a new therapeutic tool for replacing damaged or lost adult tissues. …”
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Cell culture expansion media choice affects secretory, protective and immuno-modulatory features of adipose mesenchymal stromal cell-derived secretomes for orthopaedic applications by Enrico Ragni, Andrea Papait, Michela Maria Taiana, Paola De Luca, Giulio Grieco, Elsa Vertua, Pietro Romele, Cecilia Colombo, Antonietta Rosa Silini, Ornella Parolini, Laura de Girolamo

“…Secretomes effect was tested in in vitro models of chondrocytes, lymphocytes and monocytes to mimic the OA microenvironment. …”
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Effects of Yanghe Decoction on IL-1 and TNF-α of Papain in Rabbit Knee Osteoarthritis by Zhenqiang HONG, Hongjian GAO, Junjun HE, Zeling HUANG

“…Compared with the model group, the cartilage defects in the Yanghe decoction group and the Jingu Tongxiao pill group were alleviated, the morphology and structure of cartilage was neat, the number of chondrocytes increased, the tidal line was clear, the Mankin's score decreased, and the levels of IL-1 and TNF-α in serum and synovial fluid decreased, and the difference was statistically significant (<italic>P</italic>&lt;0.05). …”
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Inhibitory effects of Spirulina in zymosan-induced arthritis in mice by Diadelis Remirez, Ricardo González, Nelson Merino, Sandra Rodriguez, Odelsa Ancheta

“…Histopathological and ultrastructural studies showed inhibition of the inflammatory reaction, whereas no destruction of cartilage, well-preserved chondrocytes, and normal rough endoplasmic reticulum and mitochondria were seen. …”
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Torn ACL: A New Bioengineered Substitute Brought from the Laboratory to the Knee Joint by Francine Goulet, Denis Rancourt, Réjean Cloutier, Pierrot Tremblay, Anne-Marie Belzil, Jean Lamontagne, Marc Bouchard, Julie Tremblay, Louis-Mathieu Stevens, Julie Labrosse, Eve Langelier, Marc D. McKee

“…At the implants' insertion sites, characteristic fibrocartilage was observed having well aligned chondrocytes and collagen fibrils. After a year, mechanical rupture of the grafts demonstrated a major gain in strength. …”
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Expression of Integrin Alpha10 Is Induced in Malignant Melanoma by Ann-Kathrin Wenke, Christian Kjellman, Evy Lundgren-Akerlund, Christian Uhlmann, Nikolas K. Haass, Meenhard Herlyn, Anja K. Bosserhoff

“…Recently, integrin alpha10 was described as a collagen type II-binding integrin expressed mainly in chondrocytes. However, by array studies we detected integrin alpha10 also to be upregulated in malignant melanoma compared to primary melanocytes. …”
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Tri-Lineage Differentiation Potential of Stem Cells from Human Exfoliated Deciduous Teeth - An In-vitro Study by Ratna Yumkham, C Nagarathna, B. S. Shakuntala, Rajkumari Sarada, Gargi Yumnam, Bandana Waikhom

“…Result: The stem cells derived from dental pulp had a comparatively high ability for proliferation and successfully differentiated into chondrocytes and osteocytes while less significant for adipocytes. …”
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Ferroptosis plays a role in osteoarthritis by Ruba Altahla, Jamal Alshorman, Xu Tao

“…Furthermore, we discuss the roles of ferrioptosis in different aspects of osteoarthritis, encompassing the degradation of cartilage, synovitis, dysfunction of chondrocytes, and the manifestation of OA-related pain. …”
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Hydrogen Supplementation of Preservation Solution Improves Viability of Osteochondral Grafts by Takuya Yamada, Kentaro Uchida, Kenji Onuma, Jun Kuzuno, Masanobu Ujihira, Gen Inoue, Bunpei Sato, Ryosuke Kurokawa, Rina Sakai, Masashi Takaso

“…However, the long-term cold preservation of OCTs in DMEM containing hydrogen was associated with the most optimal maintenance of chondrocytes with respect to viability and morphology. …”
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Current Therapeutic Strategies for Stem Cell-Based Cartilage Regeneration by Yoojun Nam, Yeri Alice Rim, Jennifer Lee, Ji Hyeon Ju

“…We also review the chondrogenic potential of cells according to their origin, including autologous chondrocytes, mesenchymal stem cells, and induced pluripotent stem cells.…”
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Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering by Stefano Focaroli, Gabriella Teti, Viviana Salvatore, Isabella Orienti, Mirella Falconi

“…., transforming growth factor betas (TGF-βs) or bone morphogenetic proteins (BMPs)) to direct hADSC differentiation into cartilage-producing chondrocytes.…”
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Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis by Qinghua Fang, Chun Zhou, Kutty Selva Nandakumar

“…Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS), and other matrix lysing enzymes that could disturb the immune balance leading to cartilage and bone damage. …”
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Differential Characterization of Two Kinds of Stem Cells Isolated from Rabbit Nucleus Pulposus and Annulus Fibrosus by Chenglin Sang, Xuecheng Cao, Fangjing Chen, Xuekang Yang, Yongxian Zhang

“…We aimed to figure out whether NP and AF also contain stem cells and whether these stem cells share common properties with chondrocytes and/or fibroblasts in their phenotypes or whether they are completely different types of cells with different characteristics. …”
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DNA-encoded dynamic hydrogels for 3D bioprinted cartilage organoids by Ziyu Chen, Hao Zhang, Jingtao Huang, Weizong Weng, Zhen Geng, Mengmeng Li, Jiacan Su

“…Articular cartilage, composed of chondrocytes within a dynamic viscoelastic matrix, has limited self-repair capacity, posing a significant challenge for regeneration. …”
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Adipose-Derived Mesenchymal Stromal/Stem Cells: Tissue Localization, Characterization, and Heterogeneity by Patrick C. Baer, Helmut Geiger

“…ASCs possess a high plasticity and differentiate into various cell types, including adipocytes, osteoblasts, chondrocytes, myocytes, hepatocytes, neural cells, and endothelial and epithelial cells. …”
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