Association of antihypertensive drug target genes with alzheimer’s disease: a mendelian randomization study by He Zheng, Chaolei Chen, Yingqing Feng

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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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Case report: Long-term GPS tracking throughout the breeding and non-breeding seasons of the streaked shearwater Calonectris leucomelas by Taito Kamata, Masaki Shirai, Kazuhiko Hirata, Takahiro Sato, Haruka Mukai, Maki Yamamoto, Tsuneo Sekijima

“…During the non-breeding season, one bird wintered in the South China Sea and the other off northern New Guinea. …”
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Nanopore Confinement Effect on the Phase Behavior of CO2/Hydrocarbons in Tight Oil Reservoirs considering Capillary Pressure, Fluid-Wall Interaction, and Molecule Adsorption by Zhixue Zheng, Yuan Di, Yu-Shu Wu

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Experimental and modeled analysis of contaminant mobility in coal fly ash landfills under continuous rainfall regimes by Shuyuan Xu, Yongbo Zhang, Jiangbo Guo, Aijing Wu, Xinghua Xiang, Haodong Sun

“…Abstract In China, a significant amount of coal fly ash is stored or used for landfill reclamation. …”
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Research on path planning for coal mine rescue robots by ZHU Hongbo, YIN Hongliang

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Expression Analysis of Heavy-Chain-Only Antibodies in Cloudy Catshark and Japanese Bullhead Shark by Reo Uemura, Susumu Tanimura, Nao Yamaguchi, Ryuichi Kuroiwa, Gabriel Takashi Andrés Tsutsumi, Toshiaki Fujikawa, Kiyoshi Soyano, Kohsuke Takeda, Yoshimasa Tanaka

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Integrated Analysis and Validation of Ferroptosis-Related Genes Associated with Ischemia/Reperfusion Injury in Lung Transplantation by Li Q, Yin J, Lin Q, He J, Shi X, Nie H

“…Qingqing Li,* Jing Yin,* Qibin Lin, Jilong He, Xiu Shi, Hanxiang Nie Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hanxiang Nie, Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuchang District, Wuhan, 430060, People’s Republic of China, Email nhxiang@whu.edu.cnBackground: Lung transplantation is the only effective therapeutic option for patients with end-stage lung disease. …”
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Study on hsa_circ_101209 in Plasma of Pregnant Women with Deep Venous Thrombosis by Zhang Y, Li J

“…Yuhong Zhang, Jun Li Center for Obstetrics and Reproductive Medicine, The Affiliated Hospital of Yunnan University, Kunming City, Yunnan Province, 650032, People’s Republic of ChinaCorrespondence: Jun Li, Center for Obstetrics and Reproductive Medicine, The Affiliated Hospital of Yunnan University, No. 176, Qingnian Road, Kunming, Yunnan, 650032, People’s Republic of China, Email lijun1152061295@hotmail.comBackground: This study analyzed the expression and diagnostic value of hsa_circ_101209 in plasma of pregnant women with in deep vein thrombosis (DVT).Methods: By circRNA microarray detection and GO/KEGG analysis, hsa_circ_14797 targeting miRNA-mRNA network was predicted. …”
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Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis by Yang C, Lei C, Jing G, Xia Y, Zhou H, Wu D, Zuo J, Gong H, Wang X, Dong Y, Aidebaike D, Wu X, Song X

“…Cheng Yang,1,* Chuntian Lei,1,* Guoqing Jing,1 Yun Xia,1 Huimin Zhou,1 Die Wu,1 Jing Zuo,1 Hailong Gong,1 Xing Wang,1 Yingyue Dong,1 Delida Aidebaike,1 Xiaojing Wu,2 Xuemin Song1 1Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, 430062, People’s Republic of China; 2Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, 430060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaojing Wu; Xuemin Song, Email RM000851@whu.edu.cn; xueminsong@whu.edu.cnBackground: Sepsis, as a clinically critical disease, usually induces coagulation disorders. …”
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Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production by Zhang L, Liu Y, Wang H, Guo S, Lv J

“…Laibin Zhang, Yuan Liu, Huanhuan Wang, Shuangyan Guo, Jieli Lv School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, 453003, People’s Republic of ChinaCorrespondence: Laibin Zhang; Jieli Lv, School of Pharmacy, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, Henan, 453003, People’s Republic of China, Email zhanglb@xxmu.edu.cn; jielilv2009@xxmu.edu.cnPurpose: Angesinenolide B (ASB), a phthalide dimer with a peroxy bridge, is uniquely isolated from Chinese medicine Angelica sinensis radix and demonstrates significant anti-inflammatory properties. …”
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Measurement report: Exploring the variations in ambient BTEX in urban Europe and their environmental health implications by X. Liu, X. Zhang, M. Dufresne, T. Wang, L. Wu, R. Lara, R. Seco, M. Monge, A. M. Yáñez-Serrano, A. M. Yáñez-Serrano, A. M. Yáñez-Serrano, M. Gohy, P. Petit, A. Chevalier, M.-P. Vagnot, Y. Fortier, A. Baudic, V. Ghersi, G. Gille, L. Lanzi, V. Gros, L. Simon, H. Héllen, S. Reimann, Z. Le Bras, M. J. Müller, D. Beddows, S. Hou, Z. Shi, R. M. Harrison, W. Bloss, J. Dernie, S. Sauvage, P. K. Hopke, P. K. Hopke, X. Duan, T. An, A. C. Lewis, J. R. Hopkins, E. Liakakou, N. Mihalopoulos, N. Mihalopoulos, X. Zhang, A. Alastuey, X. Querol, T. Salameh

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Catalytic Behaviors of Expansible Graphite in the Synthesis of Butyl Acetate by Xiu-Yan Pang

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Remarks on a Class of Nonlinear Schrödinger Equations with Potential Vanishing at Infinity by Hongbo Zhu

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Local Projection-Based Stabilized Mixed Finite Element Methods for Kirchhoff Plate Bending Problems by Xuehai Huang

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Weighted Composition Operators from Hardy Spaces into Logarithmic Bloch Spaces by Flavia Colonna, Songxiao Li

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Research on trust measurement method for initial access of industrial internet edge terminals by Ya YU, Yusun FU

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Electrochemical Sensor for Determination of Parathion Based on Electropolymerization Poly(Safranine) Film Electrode by Xingyuan Liu

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Difficulty in genetic counseling of an asymptomatic carrier woman with a de novo 15q13.2q13.3 microdeletion encompassing CHRNA7 and OTUD7A and recurrent 15q13.2q13.3 microdeletion... by Chih-Ping Chen

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Hybrid Extragradient Iterative Algorithms for Variational Inequalities, Variational Inclusions, and Fixed-Point Problems by Lu-Chuan Ceng, Ching-Feng Wen

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