Chronic Rhinosinusitis with Nasal Polyps and Biologics: A Call for Better Data Standardisation and Presentation in Clinical Studies by Kariyawasam HH, Langan D, Rimmer J

“…Harsha Hemantha Kariyawasam,1,2 Dean Langan,3 Joanne Rimmer4– 6 1Specialist Allergy and Clinical Immunology, Royal National ENT Hospital, London, UK; 2Rhinology Section, Royal National ENT Hospital, London, UK; 3Great Ormond Street Institute of Child Health, UCL, London, UK; 4Department of Otolaryngology Head & Neck Surgery, Monash Health, Melbourne, Australia; 5Department of Surgery, Monash University, Melbourne, Australia; 6Department of Otolaryngology Head & Neck Surgery, St Vincent’s Hospital, Melbourne, AustraliaCorrespondence: Harsha Hemantha Kariyawasam, Specialist Allergy and Clinical Immunology, Rhinology Section, Royal National ENT Hospital London and UCLH NHS Foundation Trust, 47-49 huntley Street, London, WC1E 6DG, UK, Email harsha.kariyawasam@nhs.netAbstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) is often severe, debilitating and difficult to treat. …”
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Recent advances in the biosynthesis of polysaccharide-based antimicrobial glycoconjugate vaccines by Yuhui Wang, Yuhui Wang, Yuhui Wang, Yuhui Wang, Haodi Liu, Haodi Liu, Haodi Liu, Haodi Liu, Baoying Wang, Baoying Wang, Baoying Wang, Baoying Wang, Gülzire Gheyret, Jingliang Qin, Hanlin Wang, Hanlin Wang, Hanlin Wang, Hanlin Wang, Yuhan Di, Yuhan Di, Yuhan Di, Yuhan Di, Yanling Wang, Juan Wang, Haining Tan, Haining Tan, Haining Tan, Haining Tan

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Building resilient cattle through better management of buffalo health by Alfredo Sánchez, Merilio Montero

“…Resilience development involves maximizing immunity, based on genetic programs and selection for individual health and product; In health management strategies that strengthen mother/child interaction from birth; In which the colostrum is guaranteed in time and form; In which anthelmintic treatments respond to a rational use on populations with parasitic pathological loads, and that have a minimum environmental impact (on dung insects, grassland ecosystems and edaphic factors), or on the dynamics of the ecosystems; Where the (restricted and cautious) use of antimicrobials prevents the continued proliferation of resistance, nor compromises human health. …”
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Age-related differences in borderline personality disorder traits and childhood maltreatment: a cross-sectional study by GuoRong Li, Yong Lin, Yun Xu, Yong Zhou, YanYan Wei, LiHua Xu, XiaoChen Tang, Zixuan Wang, Qiang Hu, JiJun Wang, HaiSu Wu, ZhengHui Yi, TianHong Zhang

“…BPD traits were assessed using the Personality Diagnostic Questionnaire 4th Edition Plus (PDQ-4+), and CM experiences were evaluated using the Child Trauma Questionnaire Short Form (CTQ-SF). Participants were categorized into three age groups: adolescents (15-21 years), young adults (22-30 years), and older adults (31-50 years).ResultsAdolescents reported significantly higher frequencies of BPD traits and diagnoses compared to young adults and older adults (p=0.036). …”
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A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes by Stefano Zucchini, Andrea E. Scaramuzza, Riccardo Bonfanti, Pietro Buono, Francesca Cardella, Vittoria Cauvin, Valentino Cherubini, Giovanni Chiari, Giuseppe d’Annunzio, Anna Paola Frongia, Dario Iafusco, Giulio Maltoni, Ippolita Patrizia Patera, Sonia Toni, Stefano Tumini, Ivana Rabbone, Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED)

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Micronutrient status, food security, anaemia, Plasmodium infection, and physical activity as predictors of primary schoolchildren's body composition in Côte d'Ivoire by Kurt Z. Long, Kurt Z. Long, Sylvain G. Traoré, Sylvain G. Traoré, Kouadio B. Kouassi, Kouadio B. Kouassi, Jean T. Coulibaly, Jean T. Coulibaly, Bomey C. Gba, Bomey C. Gba, Daouda Dao, Daouda Dao, Johanna Beckmann, Christin Lang, Harald Seelig, Nicole Probst-Hensch, Nicole Probst-Hensch, Uwe Pühse, Markus Gerber, Jürg Utzinger, Jürg Utzinger, Bassirou Bonfoh, Bassirou Bonfoh, Bassirou Bonfoh

“…Food insecurity was inversely associated with FFM among boys from lower socio-economic status (SES) households while increased MVPA was associated with reduced fat mass among girls.ConclusionsThe integration of Malaria control programs with efforts to improve household healthy diet and promote physical activity can lead to improvements in body composition and overall child health and wellbeing.…”
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Not just about pills: Findings from a national survey of pharmacists to understand their views on addressing social determinants of health by Katherine A. Meehan, Austin R. Waters, Mary Wangen, Olufeyisayo O. Odebunmi, Renée M Ferrari, Macary W. Marciniak, Alison T. Brenner, Stephanie B. Wheeler, Parth D. Shah

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Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis by Hongmei Zhao, Hongmei Zhao, Juan Zhou, Lingzhi Yuan, Zhiyi Sun, Yi Liu, Xinyu Zhao, Feng Ye

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Novel Procedures for Evaluating Autism Online in a Culturally Diverse Population of Children: Protocol for a Mixed Methods Pathway Development Study by Venus Mirzaei, Jeanne Wolstencroft, Georgia Lockwood Estrin, Eleanor Buckley, Shermina Sayani, Panos Katakis, Reena Anand, Tessa Squire, Eleanor Short, Paige Frankson, David Skuse, Michelle Heys

“…The study will take place in a socio-economically deprived, ethnically diverse inner-London Borough within a community-based child health National health service responsible for the Autism assessment of children and young people up to the age of 13 years. …”
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Clinical outcomes among HIV positive babies below 18 months of age, diagnosed under the Early Infant Diagnosis (EID) programme, India: a mixed-methods studyResearch in context by Suchit Kamble, Nilesh Gawde, Shilpa Bembalkar, Noopur Goel, Mohan Thorwat, Kalyani Nikhare, Sushmita Kamble, Radhika Brahme, Swapna Pawar, Harsh Kubavat, Bhawanisingh Kushwaha, Vinita Verma, Chinmoyee Das, Raman Gangakhedkar

“…Demand-side issues such as stigma and discrimination at family, community, and societal levels, desperation about the survival of the child, supply-side factors such as remote access to paediatric ART centres, and lack of paediatric ART medicine formulations were associated with ART treatment. …”
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Geographic variation in modern contraceptive utilization among women of reproductive age in Mozambique: a multilevel analysis by Habtu Kifle Negash, Destaye Tirite Gelaw, Mihret Getnet, Hiwot Tezera Endale, Tseganesh Asefa, Fethiya Seid Hasen, Yihun Tefera Ayenew, Nebebe Demis Baykemagn, Trualem Zeleke Yehuala, Winta Tesfaye

“…Abstract Background Modern contraceptives are crucial for reducing maternal and child mortality, yet Mozambique’s contraceptive prevalence rate is very low, with significant regional disparities. …”
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Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy (PPOIT) in inducing desensitisation or toleran... by Michael O’Sullivan, Michael S Gold, Francesca Orsini, Adriana Chebar Lozinsky, Paxton Loke, Susan L. Prescott, Patrick Quinn, Audrey DunnGalvin, Mimi LK Tang, Anne-Louise Ponsoby, Ee Lyn Su, Marnie Robinson, Dean Tey, Kuang-Chih Hsiao, Molly O’Sullivan, Christine Axelrad, Sigrid Pitkin, Jessica Metcalfe, Susan Fahy-Scheer, Thalayasingam Meera, Jovanka King, Fuad Abass, Abigail Cheung, Rachel Wallace, Samara Baldwin

“…The dual primary outcomes are: (1) the proportion of children who attain 8-week SU in the PPOIT group versus placebo group and (2) the proportion of children who attain 8-week SU in the PPOIT group versus OIT group.Ethics and dissemination This study has been approved by the Human Research Ethics Committees at the Royal Children’s Hospital (HREC 35246) and the Child and Adolescent Health Service (RGS 2543). Results will be published in peer-reviewed journals and disseminated via presentations at international conferences.Trial registration number ACTRN12616000322437.…”
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Evaluation of Elexacafor/Tezacaftor/Ivacaftor therapy after lung transplantation in Cystic Fibrosis: The Dutch National KOALA study by Johanna P. van Gemert, Bart Luijk, Merel E. Hellemons, Klara A. Visser, Carina.M.E. Hansen, Renske van der Meer, C. Tji Gan, Hester van der Vaart, Onno W. Akkerman, Willie N. Steenhuis, Marieke Verkleij, Harry G.M. Heijerman, Erik A.M. Verschuuren

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Polybrominated Dibenzo-p-dioxins/Furans (PBDD/Fs) and Diphenyl Ethers (PBDEs) in the Indoor and Outdoor of Gymnasiums by Ching-Kai Su, Jian-He Lu, How-Ran Chao, Wei-Hsiang Chang, Ming-Hsien Tsai, Chih-Lung Wang, I-Cheng Lu, Yu-Ting Chang, Hsiao-Chi Chuang, Wan-Nurdiyana-Wan Mansor, Yi-Chyun Hsu, Ying-I Tsai, Shang-Ming Ma

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Liver transplantation for homozygous familial hypercholesterolemia: a retrospective analysis from Chinese experience by Hao-Su Zhan, Lin Wei, Wei Qu, Zhi-Gui Zeng, Ying Liu, Yu-Le Tan, Jun Wang, Liang Zhang, En-Hui He, Guang-Peng Zhou, Hai-Ming Zhang, Zhi-Jun Zhu, Li-Ying Sun

“…Results Xanthoma and decreased activity tolerance were the primary clinical manifestations in the 7 HoFH children initially assessed (one child died suddenly prior to surgery due to cardiac arrest). …”
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Artificial Intelligence–Related Dental Research: Bibliometric and Altmetric Analysis by Wei Lu, Xueqian Yu, Yueyang Li, Yi Cao, Yanning Chen, Fang Hua

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Achieving reliable patient reported outcomes collection to measure health care improvement in a learning health network: lessons from pediatric rheumatology care and outcomes impro... by Nancy Pan, Nancy Pan, Esi M. Morgan, Meghan Ryan, Beth Gottlieb, Beth Gottlieb, Julia G. Harris, Julia G. Harris, Tzielan Lee, Tzielan Lee, Y. Ingrid Goh, Y. Ingrid Goh

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Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review by Laya Jalilian-Khave, Razi Kitaneh, Binah Baht Ysrayl, Anna Borelli, Melissa C. Funaro, Marc N. Potenza, Gustavo A. Angarita

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A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis by Ruidong Mo, Zhenglan Zhang, Yanmei Zhou, Yue Wang, Pengbo Yin, Chenxi Zhang, Haoshuang Fu, Cong Qian, Xiaogang Xiang, Rongkun Yin, Qing Xie

“…Compared to MELD score, Child-Turcotte-Pugh (CTP) score or apoAI, Lip-ACLFs was superior for the prediction of 90-day outcomes (receiver operating characteristic curve (ROC): 0.930 vs. 0.885, 0.833 or 0.856, all P < 0.01), as was the validation cohort (ROC 0.906 vs. 0.839, 0.857 or 0.837, all P < 0.05). …”
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Assessment of maternal healthcare services among the women of reproductive age in the rural municipality of Nepal: a cross-sectional study by Mukesh Adhikari, Manish Rajbanshi, Anita Karki, Richa Aryal, Bishnu Prasad Choulagai

“…It is essential to assess the current status of antenatal care (ANC), uptake of skilled birth attendants (SBAs), and postnatal care (PNC) to improve the health of a mother and child in developing countries like Nepal. This study assesses the utilisation and factors associated with maternal healthcare services among reproductive-aged women in the Shubhakalika Rural municipality of Nepal.Methods A cross-sectional study using proportionate simple random sampling was performed to select 180 participants. …”
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