Prevalence and determinants of HIV among reproductive-age women (15–49 years) in Africa from 2010 to 2019: a multilevel analysis of demographic and health survey data by Alemu Gedefie, Amare Muche, Anissa Mohammed, Aznamariam Ayres, Dagnachew Melak, Eyob Tilahun Abeje, Fekade Demeke Bayou, Fekadeselassie Belege Getaneh, Lakew Asmare, Abel Endawkie

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Integrating single-cell RNA-Seq and bulk RNA-Seq data to explore the key role of fatty acid metabolism in hepatocellular carcinoma by Hua Dai, Xin Tao, Yuansen Shu, Fanrong Liu, Xiaoping Cheng, Xiushen Li, Bairui Shu, Hongcheng Luo, XuXiang Chen, Zhaorui Cheng

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Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study by Tamara Liana Zocche, Cláudia Maccali, Fernanda Cristina de Augustinho, Elayne Cristina de Morais Rateke, Camila Matiollo, Ariane Borgonovo Rayes, Dariana Carla Maggi, Esther Buzaglo Dantas-Corrêa, Leonardo de Lucca Schiavon, Janaina Luz Narciso-Schiavon

“…The mean age was 55.68±11.21 years, and 71.8% were males with a mean MELD of 15.65±5.64 and 41.4% Child-Pugh C. Early readmission occurred in 91 cases (32.5%). …”
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design by Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor

“…Based on this rigorous preclinical evaluation, our validated clinical grade lintuzumab-CD28/CD3ζ CD33CART immunotherapy is now under evaluation in a first-in-child/first-in-human phase 1 clinical trial for children and adolescents/young adults with relapsed/refractory AML.Trial registration number clinicaltrials.gov; NCT03971799.…”
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Internalizing and externalizing symptoms in individuals with neurofibromatosis type 1: a systematic review and meta-analysis by Dan Liu, Liyan Yu, Xian Wu, Julia Moreira, Benjamin Felipe Mujica, Elora Shelly Mukhopadhyay, Angelena Novotney, André B. Rietman, Yang Hou

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Determinants of healthcare utilization under the Indonesian national health insurance system – a cross-sectional study by Qinglu Cheng, Rifqi Abdul Fattah, Dwidjo Susilo, Aryana Satrya, Manon Haemmerli, Soewarta Kosen, Danty Novitasari, Gemala Chairunnisa Puteri, Eviati Adawiyah, Andrew Hayen, Anne Mills, Viroj Tangcharoensathien, Stephen Jan, Hasbullah Thabrany, Augustine Asante, Virginia Wiseman

“…Fewer than 5% of the study population had visited hospitals for inpatient care and about 23% used maternal and child health services in the past 12 months. Age, gender and self-rated health were key determinants of health services utilization. …”
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Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study by Tamara Liana Zocche, Cláudia Maccali, Fernanda Cristina de Augustinho, Elayne Cristina de Morais Rateke, Camila Matiollo, Ariane Borgonovo Rayes, Dariana Carla Maggi, Esther Buzaglo Dantas-Corrêa, Leonardo de Lucca Schiavon, Janaina Luz Narciso-Schiavon

“…The mean age was 55.68±11.21 years, and 71.8% were males with a mean MELD of 15.65±5.64 and 41.4% Child-Pugh C. Early readmission occurred in 91 cases (32.5%). …”
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School-based screening for childhood anxiety problems and intervention delivery: a codesign approach by Tamsin Ford, Alastair Gray, Cathy Creswell, Victoria Williamson, Obioha Ukoumunne, Falko Sniehotta, Mara Violato, Ian McDonald, Paul Brown, Paul Stallard, Michael Larkin, Tessa Reardon, Samantha Pearcey, Claire Hill, Susan H Spence, Maria Breen, Jason Stainer, Michelle Sancho, Roberta Button, Iheoma Green, Fran Morgan, Bec Jasper

“…This article is a process-based account of how we used codesign to develop a primary school-based screening and intervention programme for child anxiety problems.Design Codesign.Setting UK primary schools.Participants Data were collected from year 4 children (aged 8–9 years), parents, school staff and mental health practitioners.Results We report how the developed programme was experienced and perceived by a range of users, including parents, children, school staff and mental health practitioners, as well as how the programme was adapted following user feedback.Conclusions We reflect on the mitigation techniques we employed, the lessons learnt from the codesign process and give recommendations that may inform the development and implementation of future school-based screening and intervention programmes.…”
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Evaluation of three-dose fosfomycin tromethamine in the treatment of patients with urinary tract infections: an uncontrolled, open-label, multicentre study by Shan Chen, Yong Yang, Bo Yang, Ming Chen, Kai Zhang, Yi Wang, Lu-Dong Qiao, Bo Zheng, Hong-Feng Guo, Yuan-Jie Niu, Ben-Kang Shi, Wei-Min Yang, Xiao-Kun Zhao, Xiao-Feng Gao

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Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The “Village Bondeko” Center, In Kinshasa by Masamba GR, Sokolo Gedikondele J, Longo-Mbenza B, Nganga Nkanga MS, Matanda Nzanza R, Matonda-ma-Nzuzi T, Ikanga J, Nge Okwe A, Lema Mabwaka G, Mawalala Malengele H, Nangi Mampuya C, Lumbu Malundama D

“…Grace Réjane Masamba,1,2 Jerôme Sokolo Gedikondele,1 Benjamin Longo-Mbenza,3– 5 Mireille Solange Nganga Nkanga,6 Richard Matanda Nzanza,1,2 Thierry Matonda-ma-Nzuzi,7 Jean Ikanga,8 Augustin Nge Okwe,3 Gabriel Lema Mabwaka,1 Héritier Mawalala Malengele,3,9 Cédrick Nangi Mampuya,1 Damien Lumbu Malundama1 1Department of Specialties, Otolaryngology Department, University Clinics of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo; 2Faculty of Medicine, Protestant University of Congo, Kinshasa, Democratic Republic of Congo; 3Department of Public Health, Lomo University of Research, Kinshasa, Democratic Republic of Congo; 4Cardiology Service, Cliniques Universitaires de Kinshasa, Kinshasa, Democratic Republic of Congo; 5Walter Sisulu University, Mthatha, South Africa; 6Department of medical biology, clinical biology service, University of Kinshasa, Kinshasa, Democratic Republic of Congo; 7Department of psychiatry, Child psychiatry service, University of Kinshasa, Kinshasa, Democratic Republic of Congo; 8Department of psychiatry, Neuropsychology service, University of Kinshasa, Kinshasa, Democratic Republic of Congo; 9Department of Radiology and Medical Imaging, Kinshasa University Clinics, Université de Kinshasa, Kinshasa, Democratic Republic of CongoCorrespondence: Benjamin Longo-Mbenza, Faculty of Health Science, Mthatha, South Africa, Tel +243 814396257, Email longombenza@gmail.comContext: Several data from the literature have focused on the relationship between congenital sensorineural hearing loss, as well as acquired hearing loss, and their impact on cognition and the risk of dementia. …”
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Did the resurgence of childhood lower respiratory infections offset the initial benefit of COVID-19-related non-pharmaceutical interventions in children? A time-series analysis by Inès Fafi, Zein Assad, Léa Lenglart, Zaba Valtuille, Florentia Kaguelidou, Camille Aupiais, Aurélie Bourmaud, Alexis Rybak, Stéphane Bechet, Corinne Levy, Robert Cohen, Bruno Frandji, Andreas Werner, François Angoulvant, Romain Basmaci, Naïm Ouldali

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Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia by Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes

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Recovery trajectories of mental health symptoms among Chinese adolescents following the end of COVID-19 by Jun Peng, Meihui He, Yongxing Guo, Yongxing Guo, Yongxing Guo, Jiangdong Diao, Jiangdong Diao, Kun Chen, Ziyi Deng, Lei Mo, Ruixiang Gao

“…Being female, senior high school students, and the oldest child in the family hindered mental health recovery, whereas parenting styles of companionship, empathetic support, promise fulfillment, and behavior intervention served as protective factors.ConclusionThis study is one of the first to reveal the post-pandemic mental health recovery trajectories of Chinese adolescents, highlighting the importance of considering both the number and severity of cumulative mental health problems. …”
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A Mobile App for Promoting Breastfeeding-Friendly Communities in Hong Kong: Design and Development Study by Heidi Sze Lok Fan, Emily Tsz Yan Leung, Ka Wing Lau, Janet Yuen Ha Wong, Edmond Pui Hang Choi, Christine Lam, Marie Tarrant, Hextan Yuen Sheung Ngan, Patrick Ip, Chia Chin Lin, Kris Yuet Wan Lok

“…In phase 1, a meeting was held with experts, including maternal and child health researchers, app developers, breastfeeding individuals, and health professionals, to discuss the focus and functionality of the breastfeeding app. …”
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Comparison of biodegradable and durable polymer drug-eluting stents in acute coronary syndrome: a meta-analysis by Tingting Wei, Can Huang, Yifan Zeng, Haoyong Yuan, Zhongshi Wu, Ting Lu, Yalin Liu

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Race as a prognostic factor of breast mucinous carcinoma by Dingyuan Wang, Yang Wang, Songlin Gao, Rongshou Zheng, Guijian Wu, Jianping Wang, Can Lu, Kena Bu, Chun Zhang, Wanqing Chen, Bailin Zhang

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Silk Protein Gene Engineering and Its Applications: Recent Advances in Biomedicine Driven by Molecular Biotechnology by Ji X, Li Y, Wang J, Wang G, Ma B, Shi J, Cui C, Wang R

“…Xingxiang Ji,1,* Yanyan Li,2,* Jingsheng Wang,3,* Gang Wang,3,* Bin Ma,4 Jingfei Shi,5 Chao Cui,6,7 Ruiming Wang1 1State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, Shandong, 250353, People’s Republic of China; 2Key Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250014, People’s Republic of China; 3Department of Cardiovascular Medicine, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong, 271000, People’s Republic of China; 4Department of Cardiovascular Medicine, Taian City Taishan District People’s Hospital, Taian, Shandong, 271000, People’s Republic of China; 5Department of Clinical and Basic Medicine, Shandong First Medical University, Jinan, Shandong, 250000, People’s Republic of China; 6Scientific Research Department, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China; 7Department of Pharmacy, The Affiliated Taian City Central Hospital of Qingdao University, Taian, Shandong, 271000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Cui, Scientific Research Department, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou, Shandong, 253000, People’s Republic of China, Email hbkjcuichao@126.com Ruiming Wang, State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, Shandong, 250353, People’s Republic of China, Email ruiming3k@163.comAbstract: Silk protein, as a natural polymer material with unique structures and properties, exhibits tremendous potential in the biomedical field. …”
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The p110α and p110β Isoforms of Class I Phosphatidylinositol 3-Kinase Are Involved in Toll-Like Receptor 5 Signaling in Epithelial Cells by Sabine M. Ivison, Mohammed A. S. Khan, Nicholas R. Graham, Leila A. Shobab, Yu Yao, Arnawaz Kifayet, Laura M. Sly, Theodore S. Steiner

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Effect of Exogenous of Transforming Growth Factor-β1 on Pregnancy Outcome in Mice with Recurrent Pregnancy Loss by Persistent Enhancement of Placental Tissue Indoleamine 2,3-Dioxyg... by Xinghui Wen, Xiaojuan Chen, Mei Li, Jinnian Zhou, Shouli Dao, Shixiang Li, Hui Cheng, Shuyun Zhao, Guanyou Huang

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The importance of specific exercise therapy in pediatric oncology by Bianca Celine Schmidli, Céline Hammadou, Christina Schindera, Nicolas von der Weid, Uta Tacke, Oliver Faude, Sarah Koch, Fiona Streckmann

“…Peripheral neuropathy in children and adolescents treated for cancer. The Lancet Child & Adolescent Health, 2(10), 744–754. https://doi.org/10.1016/S2352-4642(18)30236-0 Wurz, A., McLaughlin, E., Lategan, C., Chamorro Vina, C., Grimshaw, S. …”
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