Iron Overload in Transfusion-Dependent Indonesian Thalassemic Patients by Pandji Irani Fianza, Anita Rahmawati, Sri Hudaya Widihastha, Shofura Afifah, Mohammad Ghozali, Andre Indrajaya, Dilli Marayuzan Akbar Pratama, Dimmy Prasetya, Teddy Arnold Sihite, Mas Rizky A. A. Syamsunarno, Djatnika Setiabudi, Suthat Fucharoen, Ramdan Panigoro

Get full text

Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord by Michal Kosinski, Anna Figiel-Dabrowska, Wioletta Lech, Lukasz Wieprzowski, Ryszard Strzalkowski, Damian Strzemecki, Lukasz Cheda, Jacek Lenart, Krystyna Domanska-Janik, Anna Sarnowska

Get full text

Anemia and Contributing Factors in Severely Malnourished Infants and Children Aged between 0 and 59 Months Admitted to the Treatment Centers of the Amhara Region, Ethiopia: A Multi... by Wubet Worku Takele, Adhanom Gebreegziabher Baraki, Haileab Fekadu Wolde, Hanna Demelash Desyibelew, Behailu Tariku Derseh, Abel Fekadu Dadi, Eskedar Getie Mekonnen, Temesgen Yihunie Akalu

Get full text

Workplace Health Promotion as a good solution to the negative impact of the financial crisis on healthcare systems by Francesco Chirico

Get full text

Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…Hao Su,1,* Xiao Shang,1,* Hongruo Liu,2 Yutong Wang,1 Yang Yu,3 Yanhua Xu,4 Kui Jiang,2,* Fengzhi Feng1,* 1Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China; 2Department of Medical Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 3Department of Obstetrics and Gynecology, Xing’an League People’s Hospital, Xing’an League, Inner Mongolia, People’s Republic of China; 4Department of Obstetrics and Gynecology, Jinan Maternity and Child Health Care Hospital, Jinan, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fengzhi Feng, Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuai Fu Yuan, Dong Cheng District, Beijing, 100730, People’s Republic of China, Email fengfz1969@sina.com Kui Jiang, Department of Medical Oncology, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China, Email jk0411@163.comPurpose: Therapeutic options for patients with platinum-resistant ovarian cancer (PROC) remain a major unmet need. …”
Get full text

The effect of active and passive smoking during pregnancy on birth outcomes: A cohort study in Shanghai by Xiaokai Wang, Xia Gao, De Chen, Xuelian Chen, Qingwei Li, Jiani Ding, Fangyuan Yu, Xiaoyun Zhu, Nannan Zhang, Yifang Chen

Get full text

Fetal cardiac function in pregnancy affected by congenital heart disease: protocol for a multicentre prospective cohort study by Anna Erenbourg, Tracie Barber, Vera Cecotti, Stefano Faiola, Ilaria Fantasia, Tamara Stampaljia, Hagai Avnet, Beata Radzymińska-Chruściel, Neama Meriki, Alec Welsh

Get full text

Advancing Pediatric Surgery: The Use of HoloLens 2 for 3D Anatomical Reconstructions in Preoperative Planning by Marco Di Mitri, Annalisa Di Carmine, Simone D’Antonio, Benedetta Maria Capobianco, Cristian Bisanti, Edoardo Collautti, Sara Maria Cravano, Francesca Ruspi, Michele Libri, Tommaso Gargano, Mario Lima

“…Background: In pediatric surgery, a comprehensive knowledge of the child’s anatomy is crucial to optimize surgical outcomes and minimize complications. …”
Get full text

Pneumonia among Under-Five Children in Northwest Ethiopia: Prevalence and Predictors—A Community-Based Cross-Sectional Study by Zewudu Andualem, Tsegaye Adane, Abiye Tigabu, Walelign Worku Yallew, Sintayehu Daba Wami, Henok Dagne, Jember Azanaw, Gebisa Guyasa, Zelalem Nigussie Azene, Mastewal Endalew

“…A community-based cross-sectional study was employed in five randomly selected clusters/subcities of Gondar City. A total of 792 child-mother/caregiver pairs in the selected subcities/clusters were included. …”
Get full text

Mortality Prediction Using SaO2/FiO2 Ratio Based on eICU Database Analysis by Sharad Patel, Gurkeerat Singh, Samson Zarbiv, Kia Ghiassi, Jean-Sebastien Rachoin

“…The hyperparameters selected to train the final models were as follows: colsample_bytree of 0.8, gamma of 1, max_depth of 3, subsample of 1, min_child_weight of 10, and scale_pos_weight of 3. The SHAP, ELI5, and XGBoost feature importance analysis demonstrates that the S/F ratio ranks as the strongest predictor for mortality amongst the physiologic variables. …”
Get full text

Towards a cervical cancer-free future: women’s healthcare decision making and cervical cancer screening uptake in sub-Saharan Africa by Bright Opoku Ahinkorah, Abdul-Aziz Seidu, Richard Gyan Aboagye, Bernard Yeboah-Asiamah Asare, Joshua Okyere, Bupe Mwamba

Get full text

Using stated-preferences methods to develop a summary metric to determine successful treatment of children with a surgical condition: a study protocol by Nigel Hall, Marian Knight, Nick Lansdale, Lisa Hinton, Charles Opondo, Simon Kenny, Stefano Giuliani, John Buckell, Oliver Rivero-Arias, Kokila Lakhoo, Alexander Macdonald, Crispin Jenkinson, Benjamin Allin, Rema Ramakrishnan, Gregor Walker, Timothy Bradnock, Karolina Kuberska, Benjamin M Craig, Goher Ayman, Anna May Long, Joanne Shepherd

“…A stated-preference study has been designed to estimate the value key stakeholders place on different elements of the outcomes for a child with a surgical condition. This study proposes to develop a summary metric to determine what represents successful treatment of children with surgical conditions.Methods and analysis Preferences from parents, individuals treated for surgical conditions as infants/children, healthcare professionals and members of the public will be elicited using paired comparisons and kaizen tasks. …”
Get full text

Predictors of specialist care referrals (SCR) following emergency department review or hospital admission in adults with previous acute COVID-19: a prospective UK cohort study by Anita Saigal, Songyuan Xiao, Owais Siddique, Prasheena Naran, Heba M Bintalib, Camila Nagoda Niklewicz, George Seligmann, Sindhu Bhaarrati Naidu, Amar J Shah, Chibueze Ogbonnaya, John R Hurst, Marc Ci Lipman, Swapna Mandal

Get full text

Exploration of neurometabolic alterations in adolescent patients with bipolar depression and non-suicidal self-injury based on proton magnetic resonance spectroscopy by Chengji Wang, Yuan Qu, Xiaoqin Shen, Xiaoxiao Tang, Xiaoxiao Tang, Gaiyu Tong, Meier Wati, Manzeremu Naibi, Manzeremu Naibi, Cheng Zhang, Shaohong Zou

“…Proton magnetic resonance spectroscopy (1H-MRS) was used to detect the ratio of biochemical metabolites in the ventromedial prefrontal cortex (vmPFC) of all patients.ResultsThere was no statistically significant difference (P>0.05) in the age, gender, only child status, residential status, education level, age of onset, disease course, family history, and 24-item Hamilton Depression Scale (HAMD) score between patients in the NSSI group and those without NSSI group. …”
Get full text

Verifying the Usefulness of Pulmonary Blood Flow Studies in the Correction of Pulmonary Atresia and Ventricular Septal Defect with Major Aortopulmonary Collateral Arteries by Zirou Huang, Fan Cao, Rongjun Zou, Minghui Zou, Weidan Chen, Wenlei Li, Guodong Huang, Li Ma, Xinxin Chen

“…Partial VSD repair was recorded for 21 children (36.84%), including 4 children (19.05%) who underwent VSD closure in the later stages and 13 children (61.90%) who were under follow-up and waiting to undergo complete VSD closure. There was only one child (1.75%) with VSD left. After eliminating the data of four unqualified cases, the ROC curve for predicting VSD closure based on 53 pulmonary blood flow studies was obtained at a p value of <0.001, with an area under the curve of 0.922. …”
Get full text

Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats by Jiong Yu, Guangshu Hao, Dan Wang, Jingqi Liu, Xiaotian Dong, Yanni Sun, Qiaoling Pan, Yang Li, Xiaowei Shi, Lanjuan Li, Hongcui Cao

Get full text

Narratives of swiss football players about talent - and positive youth development: The role of social agents and agency. by Philipp Koch, Bryan Charbonnet, Noora Ronkainen

“…Lerner (Eds.), Handbook of child psychology and developmental science: Theory and method (pp. 9–62). …”
Get full text

A Scoping Review of Existing Policy Instruments to Tackle Overweight and Obesity in India: Recommendations for a Social and Behaviour Change Communication Strategy [version 2; peer... by Lopamudra Tripathy, Suparna Ghosh-Jerath, Neena Bhatia, Kathryn Backholer, Kavita Chauhan, Nishibha Thapliyal, Deepika Bahl, Shalini Bassi, Monika Arora, Seema Chandra, Preetu Mishra

“…SBCC strategies can also be incorporated into India’s Integrated Nutrition Support Programme (POSHAN 2.0) and/or Reproductive, Maternal, New-born, Child, Adolescent Health and Nutrition (RMNCAH+N) under the National Health Mission. …”
Get full text

The mutational landscape of ARMC5 in Primary Bilateral Macronodular Adrenal Hyperplasia: an update by Lucas Bouys, Anna Vaczlavik, Isadora P. Cavalcante, Florian Violon, Anne Jouinot, Annabel Berthon, Patricia Vaduva, Stéphanie Espiard, Karine Perlemoine, Peter Kamenicky, Marie-Christine Vantyghem, Antoine Tabarin, Gérald Raverot, Cristina L. Ronchi, Ulrich Dischinger, Martin Reincke, Maria C. Fragoso, Constantine A. Stratakis, Albain Chansavang, Eric Pasmant, Bruno Ragazzon, Jérôme Bertherat, for the COMETE and ENSAT Networks

Get full text

Avascular necrosis in pediatric rheumatic diseases: an Italian retrospective multicentre study by Ivan Taietti, Federico Zini, Emilio Amleto Conti, Enrica Cristini, Irene Borzani, Giulia Ramponi, Claudia Bracaglia, Raffaele Pecoraro, Riccardo Papa, Jessica Tibaldi, Serena Pastore, Gabriele Simonini, Marco Cattalini, Antonella Meini, Achille Marino, Stefano Lanni, Francesca Minoia, Giovanni Filocamo

Get full text