A novel de novo GABRA2 gene missense variant causing developmental epileptic encephalopathy in a Chinese patient by Li Yang, Xingyu Wan, Ran Hua, Junhong Jiang, Baotian Wang, Rui Tao, De Wu

“…This study presents the clinical presentation and genetic analysis of a Chinese family with a child diagnosed with DEE78, due to a novel GABRA2 variant. …”
Get full text

Symptoms, but Not a Biomarker Response to Inhaled Corticosteroids, Predict Asthma in Preschool Children with Recurrent Wheeze by E. M. M. Klaassen, K. D. G. van de Kant, Q. Jöbsis, S. T. P. Høvig, C. P. van Schayck, G. T. Rijkers, E. Dompeling

“…At six years of age a child was diagnosed as transient wheezer or asthmatic. …”
Get full text

Comparison of IL-17 and FOXP3+ Levels in Maternal and Children Leprosy Patients in Endemic and Nonendemic Areas by Flora Ramona Sigit Prakoeswa, Faradiba Maharani, Munawaroh Fitriah, Jusak Nugraha, Hardyanto Soebono, Budi Prasetyo, Santi Martini, Dominicus Husada, Hari Basuki Notobroto, Muhammad Yulianto Listiawan, Anang Endaryanto, Cita Rosita Sigit Prakoeswa

“…We investigated the dysregulation of immune system by comparing IL-17 and FOXP3+ levels occurring in maternal and child leprosy patients in endemic and nonendemic areas. …”
Get full text

Nutritional Status and Educational Performance of School-Aged Children in Lalibela Town Primary Schools, Northern Ethiopia by Muluken Ayalew, Alemayehu Bayray, Abate Bekele, Simegnew Handebo

“…A total of 505 primary school students were included in the study. The child anthropometric measures were calculated using AnthroPlus software version 1.0.4 WHO 2007 standards. …”
Get full text

The Determinants of Sexual Intercourse Before Age 16 Years Among Rural Jamaican Adolescents by Olaniyi J. Ekundayo, Joana Dodson-Stallworth, Michele Roofe, Inmaculada B. Aban, Laura H. Bachmann, Mirjam C. Kempf, John Ehiri, Pauline E. Jolly

Get full text

Construction and Validation of a Model for Predicting Fear of Childbirth: A Cross-Sectional Population Study via Machine Learning by Zhang ZL, Chen KJ, Chen H, Zhu MM, Gu JJ, Jiang LS, Zheng L, Zhou SG

“…Zhi-Lin Zhang,* Kang-Jia Chen,* Hui Chen,* Miao-Miao Zhu, Jing-Jing Gu, Li-Shuai Jiang, Lan Zheng, Shu-Guang Zhou Department of Gynecology and Obstetrics, Maternal and Child Medical Center of Anhui Medical University, The Fifth Affiliated Clinical College of Anhui Medical University, Anhui Women and Children’s Medical Center, Hefei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shu-Guang Zhou, Email zhoushuguang@ahmu.edu.cn; Lan Zheng, Email zhenglan2022@163.comBackground: Fear of childbirth (FOC) is a psychological state of fear and distress that pregnant women experience when they approach labor. …”
Get full text

Multicomponent intervention for schoolchildren with asthma: Pilot cluster randomized controlled trial by Marina Reznik, MD, MS, Florinda Islamovic, MD, Jill S. Halterman, MD, MPH, Cheng-Shiun Leu, PhD, Jiaqing Zhang, PhD, Philip O. Ozuah, MD, PhD

“…We randomly assigned 2 schools as intervention and 2 as control sites. Child PA (primary outcome) was measured by accelerometers at 4 time points, and caregivers completed surveys on asthma symptoms. …”
Get full text

Implementation of Virtual and Face-to-Face Childbirth Preparation Training for the Spouses of the Primiparous Women to Reduce the Fear of Childbirth, Improve the Pregnancy Experien... by Zari Doaltabadi, Leila Amiri-Farahani, Seyedeh Batool Hasanpoor-Azghady

“…Men have a special role to play in promoting maternal and child health during pregnancy, childbirth, and postpartum period. …”
Get full text

Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia by Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič

“…An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to 5 days and open-label). 50 children aged 6–59 months with acute diarrhoea presenting with no or some dehydration to the emergency paediatric unit and outpatient clinic at Edward Francis Small Teaching Hospital, Banjul, The Gambia were randomised to either standard treatment (oral rehydration fluid and zinc) or standard treatment with polymethylsiloxane polyhydrate for up to 5 days.Results Recruitment was completed in 7 months. All but one child completed the study. There were no major protocol deviations although patient-held diaries did not collect reliable information. …”
Get full text

Combination Antiretroviral Therapy for HIV in Rwandan Adults: Clinical Outcomes and Impact on Reproductive Health up to 24 Months by Brenda Asiimwe-Kateera, Nienke Veldhuijzen, Jean Paul Balinda, John Rusine, Sally Eagle, Joseph Vyankandondera, Julie Mugabekazi, Pascale Ondoa, Kimberly Boer, Anita Asiimwe, Joep Lange, Peter Reiss, Janneke van de Wijgert

“…Of the women who carried at least one pregnancy to term since having been diagnosed HIV-positive, a third reported to have participated in a prevention-of-mother-to-child-transmission (PMTCT, option A) intervention. …”
Get full text

Phosphodiesterase Inhibitors Suppress Lactobacillus casei Cell-Wall-Induced NF-κB and MAPK Activations and Cell Proliferation through Protein Kinase A—or Exchange Protein Activated... by Takekatsu Saito, Naotoshi Sugimoto, Kunio Ohta, Tohru Shimizu, Kaori Ohtani, Yuko Nakayama, Taichi Nakamura, Yashiaki Hitomi, Hiroyuki Nakamura, Shoichi Koizumi, Akihiro Yachie

Get full text

Unintended Pregnancy and Associated Factors among Pregnant Women Attending Antenatal Care at Bako Tibe District Public Health Facility, Oromia Region, Ethiopia by Habtamu Bekele, Merga Dheressa, Bezatu Mengistie, Yitagesu Sintayehu, Gelana Fekadu

“…The former occurs when no child or no more children are desired, and the latter is when the conception occurs earlier than the desired time, but wanted later. …”
Get full text

Identification of Maltase Glucoamylase as a Biomarker of Acute Kidney Injury in Patients with Cirrhosis by Linda Awdishu, Shirley Tsunoda, Michelle Pearlman, Chanthel Kokoy-Mondragon, Majid Ghassemian, Robert K. Naviaux, Heather M. Patton, Ravindra L. Mehta, Bhavya Vijay, Satish P. RamachandraRao

“…Data were extracted from the electronic health record including etiology of liver disease, MELD score, history of decompensation, Child-Turcotte-Pugh score, history of AKI, and medication exposures. …”
Get full text

Mental health risk in human services work across Europe: the predictive role of employment in various sectors by Ágnes Győri, Éva Perpék, Szilvia Ádám

Get full text

Hygienic complementary feeding practice and its associated factors among mothers having children aged 6–23 months in Antsokia Gemza district, Ethiopia: a cross-sectional survey by Eyob Ketema Bogale, Tefera Chane, Getachew Tadegew

“…All mothers (biological mothers, grandmothers, sisters and others) taking responsibility for caring for a child of age 6–23 months were included in the study. …”
Get full text

Efficacy of Lurasidone in First-Episode Psychosis: Patient Phenotypes, Dosage, and Recommendations from an Expert Panel by Miquel Bernardo, Marina Díaz Marsá, Ana González-Pinto, Manuel Martín Carrasco, Víctor Pérez Sola, Pilar Alejandra Sáiz, Eduard Vieta, Marta Torrens, Celso Arango, Benedicto Crespo-Facorro

Get full text

Physical and emotional abuse with internet addiction and anxiety as a mediator and physical activity as a moderator by Jinyin Peng, Yang Liu, Xubo Wang, Zhenxiu Yi, Lei Xu, Fulan Zhang

“…After controlling for participants’ gender, grade level, and place of residence, only-child status, the study findings revealed that physical-emotional abuse significantly and positively predicted internet addiction and anxiety among university students (β = 0.157, β = 0.271, p < 0.001). …”
Get full text

Nutritional knowledge and practices of low-income women during pregnancy: a qualitative study in two Oaxacan cities by Marian Marian, Ramona L. Pérez, Amanda C. McClain, Samantha Hurst, Elizabeth Reed, Kathryn M. Barker, Rebecka Lundgren

“…Women who had at least one child in the past five years and had lived in Oaxaca for the past five years were eligible to participate. …”
Get full text

A community-based father education intervention on breastfeeding practice in Ethiopia: a quasi-experimental study by Wolde Melese Ayele, Tesfaye Birhane Tegegne, Asnakew Molla Mekonen

“…Baseline data were gathered from selected Kebeles (Kebele: the lowest administrative level in Ethiopia) to identify couples seeking care through routine maternal and child health services. Fathers in the intervention area received breastfeeding education services at health facilities or home visits during antenatal, delivery, and postpartum periods. …”
Get full text

Telaprevir: options of application in separate patient groups by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

“…AVT in patients with compensated cirrhosis, those, enrolled to liver transplantation waiting list (if MELD index ≤18 and Child-Pugh score ≤8 points), with good efficacy and adequate treatment safety profile is now available. …”
Get full text