Epithelial–Mesenchymal Transition Suppression by ML210 Enhances Gemcitabine Anti-Tumor Effects on PDAC Cells by Keisuke Takemura, Kyohei Ikeda, Hayato Miyake, Yoshio Sogame, Hiroaki Yasuda, Nobuhiro Okada, Kazumi Iwata, Junichi Sakagami, Kanji Yamaguchi, Yoshito Itoh, Atsushi Umemura

“…After several screening steps, ML210, a low molecular weight chemical, was found to suppress the epithelial–mesenchymal transition (EMT) in PDAC cells in combination with GEM. …”
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Conglomerated Imiquimod and Metronidazole Incorporated Biodegradable Nanofibrous Mats for Potential Therapy of Cervical Cancer by Chen YP, Chiu CF, Wang CN, Lin CC, Shen CR, Yao YC, Kuo YH, Liu SJ

“…Yi-Pin Chen,1,2 Chiao-Fan Chiu,3,4 Chien-Neng Wang,1 Chu-Chi Lin,1 Chia-Rui Shen,5– 7 Yi-Chen Yao,8 Yi-Hua Kuo,8 Shih-Jung Liu8,9 1Department of Obstetrics and Gynecology, Keelung Chang Gung Memorial Hospital, Keelung, 20401, Taiwan; 2School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Pediatrics, Linkou Medical Center, Chang Gung Memorial Hospital, Taoyuan, 333, Taiwan; 4Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan; 5Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Taoyuan, 33302, Taiwan; 6Department of Ophthalmology, Lin-Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan; 7R&D Center of Biochemical Engineering Technology, Department of Chemical Engineering, Ming Chi University of Technology, New Taipei, Taiwan; 8Department of Mechanical Engineering, Chang Gung University, Taoyuan, 33302, Taiwan; 9Bone and Joint Research Center, Department of Orthopedic Surgery, Chang Gung Memorial Hospital-Linkou, Taoyuan, 33305, TaiwanCorrespondence: Shih-Jung Liu, Department of Mechanical Engineering, Chang Gung University, 259, Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 33302, Taiwan, Tel +886-3-2118166, Fax +886-3-2118558, Email shihjung@mail.cgu.edu.twBackground: In clinical practice, imiquimod is used to treat Human Papillomavirus (HPV)-related lesions, such as condyloma and Cervical Intraepithelial Neoplasia (CIN). …”
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Peering into the Black Box: Forward Modeling of the Uncertainty Budget of High-resolution Spectroscopy of Exoplanet Atmospheres by Arjun B. Savel, Megan Bedell, Eliza M.-R. Kempton, Peter C. B. Smith, Jacob L. Bean, Lily L. Zhao, Kaze W. K. Wong, Jorge A. Sanchez, Michael R. Line

“…By resolving individual spectral lines, HRCCS can precisely measure chemical abundance ratios, directly constrain atmospheric dynamics, and robustly probe multidimensional physics. …”
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Cytotoxicity Potential of Endophytic Fungi Extracts from Terminalia catappa against Human Cervical Cancer Cells by Michèle Stella Majoumouo, Marius Belmondo Tincho, Rufin Marie Kouipou Toghueo, Thureyah Morris, Donavon Charles Hiss, Fabrice Fekam Boyom, Chitra Mandal

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Rearing mealworm larvae with wheat, barley or maize grains as main source of nutrients in unbalanced or balanced substrates by D. Plonquet, G. Fondevila, M. Fondevila

“…Larval weight and residual substrate were monitored weekly, and larval chemical composition was analysed at the end of each experiment. …”
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IDENTIFIKASI PIGMEN KLOROFIL DAN CELAH ENERGI PADA DAUN CINCAU (CYCLEA BARBATA) SEBAGAI FOTOSENSITIZER ALAMI UNTUK APLIKASI DSSC by Ismail Saleh, Wa Ode Nirwana Sari Halidun

“…Chlorophyll pigment absorbs energy from light and convert it into chemical energy. Moreover, it can transfer electrons, so it can be used as a natural photosensitizer on dye-sensitized solar cell (DSSC) device. …”
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Enhanced characterization of non-metallic inclusions in ultra-high-strength steels using advanced synchrotron-based X-ray absorption spectroscopy and chemometric analysis by Mourad Kharbach, Mohammed Alaoui Mansouri, Ekta Rani, Harishchandra Singh, Tuomas Alatarvas, Brice Sarpi, Lin Zhu, Yuran Niu, Alexei Zakharov, Ilkka Launonen, Marko Huttula, Mikko J. Sillanpaa, Samuli Urpelainen

“…By acquiring Ca-L2,3-edge X-ray absorption spectra from six NMIs at both room temperature and 400 °C, we analyze their structural changes, chemical compositions, and phase transformations. To extract meaningful insights from complex X-PEEM images, advanced chemometric data analysis is employed.Multivariate Curve Resolution (MCR-ALS) is utilized to provide an unbiased analysis, revealing pure spectra and concentration profiles of NMIs before and after annealing. …”
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Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2 by Brigitta Buttari, Antonella Tramutola, Ana I. Rojo, Niki Chondrogianni, Sarmistha Saha, Alessandra Berry, Letizia Giona, Joana P. Miranda, Elisabetta Profumo, Sergio Davinelli, Andreas Daiber, Antonio Cuadrado, Fabio Di Domenico

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Thermodynamics guided design and processing of a WC/HEA cermet tool for high temperature friction stir welding by Supreeth Gaddam, Surekha Yadav, Amit Kishan Behera, Noriaki Arai, Zaynab Mahbooba, Shikhar Krishn Jha, Qiaofu Zhang, Rajiv S. Mishra

“…The tools performed with no observed chemical interaction with the workpiece material. The HSLA-50 material showed improved microstructure, hardness, and tensile properties post FSW. …”
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Assessment of Different Conventional and Biofortified Wheat Genotypes Based on Biology and Damage Pattern of <i>Rhyzopertha dominica</i> and <i>Trogoderma granarium</i> by Hafiz Muhammad Bilal Yousuf, Muhammad Yasin, Muhammad Asif Khan, Asim Abbasi, Muhammad Arshad, Muhammad Anjum Aqueel, Inzamam Ul Haq, Waleed A. A. Alsakkaf, Marwa I. Mackled, Nazih Y. Rebouh, Hayssam M. Ali

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Control of two-spotted spider mite, Tetranychus urticae, on strawberry by integrating with cyetpyrafen and Phytoseiulus persimilis by Shan Zhao, Qiuyu Zhao, Xiaoyan Dai, Bing Lv, Ruijuan Wang, Zhenjuan Yin, Feng Zhang, Yan Liu, Long Su, Hao Chen, Li Zheng, Hongmei Li, Lixia Xie, Yifan Zhai

“…Management of TSSM has traditionally relied on synthetic acaricides, but to mitigate dependency on these chemicals, the control of TSSM on strawberry is often combined with biological control measures and chemical control strategies. …”
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Phytochemical and Bioactivity Evaluation of Bee Pollen and Androecia of <i>Castanea</i>, <i>Salix</i>, and <i>Quercus</i> Species by Nisa Beril Sen, Irena Vovk, Hasan Kırmızıbekmez, Etil Guzelmeric

“…Qualitative and quantitative differences in the chemical composition between bee pollen originated from <i>Castanea sativa</i> (Türkiye and Slovenia), <i>Salix</i> spp. …”
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Intermediate pyrolysis of Ficus nitida wood in a fixed-bed reactor: effect of pyrolysis parameters on bio-oil and bio-char yields and properties by Tabal, Amine, Belyazid, Oumayma, Dahman, Hicham, Berrich, Emna, Jeguirim, Mejdi, El Achaby, Mounir, El Harfi, Khalifa, Aboulkas, Adil

“…High quantity of aliphatic, phenolic ketones and aromatic groups are present in the bio-oil, which underlines the need for further upgrading for the bio-oil to be considered as a potential biofuel and valuable chemical product. The physicochemical properties of biochar show that it is a material with a high calorific value and a high percentage of carbon relative to raw biomass. …”
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MXene-based materials for enhanced water quality: Advances in remediation strategies by Ali Mohammad Amani, Milad Abbasi, Atena Najdian, Farzaneh Mohamadpour, Seyed Reza Kasaee, Hesam Kamyab, Shreeshivadasan Chelliapan, Mostafa Shafiee, Lobat Tayebi, Ahmad Vaez, Atefeh Najafian, Ehsan Vafa, Sareh Mosleh-Shirazi

“…., >1000 S/m), hydrophilicity, and chemical stability. Their strong sorption selectivity and effective reduction capacity, exemplified by heavy metal adsorption efficiencies exceeding 95 % in several studies, coupled with facile surface modification, make them suitable for removing diverse contaminants. …”
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State of charge estimation of lithium-ion battery based on state of temperature estimation using weight clustered-convolutional neural network-long short-term memory by Chaoran Li, Sichen Zhu, Liuli Zhang, Xinjian Liu, Menghan Li, Haiqin Zhou, Qiang Zhang, Zhonghao Rao

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Advancements in Nanotechnology for Enhanced Food Safety and Hygiene: Pathogen Detection, Smart Packaging, and Preservation Applications by Farhang Hameed Awlqadr, Ammar B. Altemimi, Qausar Hamed AlKaisy, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Tablo Azad H.Slih, Rawaa H. Tlay, Tarek Gamal Mohamed Abd El-Maksoud, Franscesco Cacciola

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PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

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Soil phosphorus mobilization as affected by long-term organic fertilization in a tropical Regosol by Kalline De Almeida Alves Carneiro, Tancredo Augusto Feitosa De Souza, Gislaine Dos Santos Nascimento, Vânia Da Silva Fraga, Bruno de Oliveira Dias

“…Highlights: The continuous use of higher rates of farmyard manure influences the soil chemical properties and P loss in a Regosol. Areas with long-term use of farmyard manure show a high rate of P mobilization. …”
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A dendritic hexamer acceptor enables 19.4% efficiency with exceptional stability in organic solar cells by Tao Jia, Tao Lin, Yang Yang, Lunbi Wu, Huimin Cai, Zesheng Zhang, Kangfeng Lin, Yulong Hai, Yongmin Luo, Ruijie Ma, Yao Li, Top Archie Dela Peña, Sha Liu, Jie Zhang, Chunchen Liu, Junwu Chen, Jiaying Wu, Shengjian Liu, Fei Huang

“…Recently emerging giant molecular acceptor (GMA) materials offer various advantages, such as precise chemical structure, high molecular weight (beneficial to film stability under several external stress), and impressive device efficiency, making them a promising candidate. …”
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2-Aminothiophene Derivatives—New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity by Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Roberto Pontarolo, Julyanne Maria Saraiva de Sousa, Klinger Antonio da Franca Rodrigues, Marcus Tullius Scotti, Anuraj Nayarisseri, Pascal Marchand, Francisco Jaime Bezerra Mendonça-Junior

“…Thus, new compounds were synthesized containing chemical modifications at the C-3, C-4, and C-5 positions of the 2-aminothiophene ring, in addition to the S-Se bioisosterism. …”
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