AN INTEGRATED INFORMATION SYSTEM ON BIORESOURCE COLLECTIONS OF THE FASO OF RUSSIA by S. A. Lashin, D. A. Afonnikov, M. A. Genaev, F. V. Kazantsev, E. G. Komyshev, E. A. Oschepkova, А. V. Petrov, D. A. Rasskazov, A. A. Smirnova, N. A. Kolchanov

“…Architecturally, the portal is concerned as a central node with a series of modules communicating through the unified interfaces. …”
Get full text

Surgical treatment of small- and medium-sized primary macular holes with preservation of the internal limiting membrane in the papillomacular nerve fiber bundle area by N.M. Shilov, A.V. Tereshchenko, E.V. Erokhina, S.V. Novikov, A.A. Lugovaya, A.G. Kurguzova

“…The preservation of the foveolar part of the ILM and its fragment in the projection of the PMB resulted in a high functional outcome, as evidenced by BCVA (20/25 at 12 months after surgery) and microperimetry, which showed an increase in retinal light sensitivity and disappearance of the absolute scotoma in the central fovea in all patients in the postoperative period. …”
Get full text

The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Background: Subarachnoid hemorrhage (SAH) is characterized by intense central inflammation, leading to substantial post-hemorrhagic complications such as vasospasm and delayed cerebral ischemia. …”
Get full text

Characterizing Droughts During the Rice Growth Period in Northeast China Based on Daily SPEI Under Climate Change by Tangzhe Nie, Xiu Liu, Peng Chen, Lili Jiang, Zhongyi Sun, Shuai Yin, Tianyi Wang, Tiecheng Li, Chong Du

“…The results showed that: (1) Under 3 SSP scenarios, <i>P_r</i> showed an increasing trend from the northwest to the southeast, <i>T_max</i> showed an increasing trend from the northeast to the southwest, and higher <i>T_min</i> was mainly distributed in the east and west regions. (2) <i>PET₀</i> indicated an overall interannual rise in the three future SSP scenarios, with higher values mainly distributed in the central and western regions. The mean daily <i>PET₀</i> values ranged from 4.8 to 6.0 mm/d. (3) Under SSP1-2.6, rice mainly experienced mild drought and moderate drought (−0.5 ≥ <i>SPEI</i> > −1.5). …”
Get full text

Short-Term Results of Switch from Conbercept to Bevacizumab or Ranibizumab in Eyes with Persistent Neovascular Age-Related Macular Degeneration by Zongyi Wang, Mengyang Li, Yuou Yao, Jie Hu, Jiyang Tang, Ran Tang, Zhenyu Piao, Jinfeng Qu

“…The demographic data, treatments, best-corrected visual acuity (BCVA), central macular thickness (CMT), and the height of pigmented epithelial detachment (PED) before and after switching were recorded and analyzed. …”
Get full text

Correlation of HER2 expression and clinicopathological characteristics in patients with urothelial carcinoma in China by WANG Shanshan, YE Dingwei, YANG Li, CHENG Fan, YANG Tiejun, ZHANG Xiaoping, YU Zhixian, ZHANG Qingyun, YANG Yong

“…Methods: This study was a multicenter study that retrospectively included UC patients from urology departments of 8 tertiary hospitals in 5 geographical regions of China (North China, East China, South China, Central China and Northwest) whose tissue samples were collected from January 2023 to March 2024. …”
Get full text

Clinical novel exploration of intractable fever in stroke rehabilitation: a single-center cross-sectional retrospective study by Huang Jingjie, Wu Bangqi, Qin Peng, Zhang Ziyi, Cheng Yupei, Wang Chaoran, Chen Yuyan, Bai Jing

“…Beyond infectious causes, stroke survivors often experience recurrent intractable fever due to central or neurogenic mechanisms. This study aims to retrospectively investigate the incidence and clinical characteristics of acute and intractable fever in patients undergoing stroke rehabilitation. …”
Get full text

Global, regional, and national epidemiology of childhood neuroblastoma (1990–2021): a statistical analysis of incidence, mortality, and DALYsResearch in context by Jusen Nong, Cheng Su, Changhua Li, Congjun Wang, Wei Li, Yong Li, Peng Chen, Yanqiang Li, Zihao Li, Xinjin She, Zuxin Yuan, Sentian Liu, Chao Chen, Qian Liao, Yige Luo, Bo Shi

“…Among the five Sociodemographic Index (SDI) regions, the highest EAPCs were observed in the low-to-mid SDI regions for incidence (1.87%; 95% CI, 1.64%–2.10%), mortality (1.22%; 95% CI, 1.09%–1.34%), and DALYs (1.36%; 95% CI, 1.15%–1.57%). Regionally, Central Asia exhibited the fastest annual increase in incidence (EAPC = 2.76%; 95% CI, 2.18%–3.34%). …”
Get full text

Comparison of Hyperbaric 0.5% Levobupivacaine and Hyperbaric 0.75% Ropivacaine for Intrathecal Use in Infraumbilical Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Priya Kishnani, Richa Tailor, Sara Mary Thomas

“…It has less affinity and strength of depressant effects on myocardial and Central Nervous System (CNS) vital centers in pharmacodynamic studies, along with a superior pharmacokinetic profile. …”
Get full text

Twelve-Month Outcomes and Optical Coherence Tomography (OCT) Biomarkers After Intravitreal Dexamethasone Implantation in Pseudophakic Eyes with Post-Vitrectomy Cystoid Macular Edem... by Francesco Pignatelli, Alfredo Niro, Giuseppe Addabbo, Pasquale Viggiano, Giacomo Boscia, Maria Oliva Grassi, Francesco Boscia, Cristiana Iaculli, Giulia Maria Emilia Clima, Antonio Barone, Ermete Giancipoli

“…The mean best-corrected visual acuity (BCVA; logMAR), mean central macular thickness (CMT; μm) change, and response to different treatments [medical therapy and intravitreal dexamethasone (DEX) implant] were evaluated 1, 3, 6, 9, and 12 months after PPV. …”
Get full text

Designing an Innovative Human Resources Model Based on Perceived Organizational Support Case Study of Qazvin's Government organizations by Hossein Rasouli, Morteza Mousakhani, Mahdi Alvani, parham azimi

“…Effective initiation, sustained development, and strengthening of such innovative practices are not feasible without the solid foundation of both material and spiritual support as perceived by the employees. Consequently, the central aim of this research is to meticulously design and present an innovative human resources model based significantly on perceived organizational support, meticulously studied within the government organizations of Qazvin. …”
Get full text

Response to Aflibercept Therapy in Three Types of Choroidal Neovascular Membrane in Neovascular Age-Related Macular Degeneration: Real-Life Evidence in the Czech Republic by Jan Nemcansky, Alexandr Stepanov, Michal Koubek, Miroslav Veith, Yun Min Klimesova, Jan Studnicka

“…Best-corrected visual acuity (BCVA) and central retinal thickness (CRT) were measured using Early Treatment Diabetic Retinopathy Study (ETDRS) charts and spectral-domain optical coherence tomography (OCT). …”
Get full text

Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

“…Objectives To assess the beneficial and harmful effects of duloxetine versus ‘active placebo’, placebo or no intervention for adults with major depressive disorder.Design Systematic review with meta-analysis and trial sequential analysis of randomised trials.Data sources Cochrane Central Register of Controlled Trials, MEDLINE, Embase, PsycINFO and other relevant databases up until January 2023. …”
Get full text

Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“…Saudi Arabia has pioneered the nationwide Saudi Medical Appointments and Referrals Centre (SMARC), a centralized e-referral system using artificial intelligence and predictive analytics. …”
Get full text

Metformin exerted tumoricidal effects on colon cancer tumoroids via the regulation of autophagy pathway by Roya Shabkhizan, Çığır Biray Avci, Sanya Haiaty, Marziyeh Sadat Moslehian, Fatemeh Sadeghsoltani, Ahad Bazmani, Mahdi Mahdipour, Leila Sabour Takanlou, Maryam Sabour Takanlou, Arezoo Rezaie Nezhad Zamani, Reza Rahbarghazi

“…Results The current protocol yielded typical compact tumoroids with a dark central region. Despite slight changes in released LDH contents, no statistically significant differences were achieved in terms of cell toxicity in MTF-exposed groups compared to the control tumoroids, indicating the insufficiency of MTF in the induction of tumor cell death (p > 0.05). …”
Get full text

Restructuring of small-scale constructed wetland systems and treatability of individual household wastewater through natural process by S. Mokatip, K. Chunkao, W. Wararam, S. Bualert, O. Phewnil, T. Pattamapitoon, N. Semvimol, P. Maskulrath, P. Rollap, S. Thaipakdee

“…The knowledge and application of the constructed wetland system could be suggested for the primary treatment system of domestic wastewater within municipalities, given that this system would provide support to the central wastewater treatment system for enhanced efficacy.…”
Get full text

Harnessing Big Heterogeneous Data to Evaluate the Potential Impact of HIV Responses Among Key Populations in Sub-Saharan Africa: Protocol for the Boloka Data Repository Initiative by Refilwe Nancy Phaswana Mafuya, Edith Phalane, Amrita Rao, Kalai Willis, Katherine Rucinski, K Alida Voet, Amal Abdulrahman, Claris Siyamayambo, Betty Sebati, Mohlago Seloka, Musa Jaiteh, Lerato Lucia Olifant, Katharine Journeay, Haley Sisel, Xiaoming Li, Bankole Olatosi, Neset Hikmet, Prashant Duhoon, Francois Wolmarans, Yegnanew A Shiferaw, Lifutso Motsieloa, Mashudu Rampilo, Stefan Baral

“… BackgroundIn South Africa, there is no centralized HIV surveillance system where key populations (KPs) data, including gay men and other men who have sex with men, female sex workers, transgender persons, people who use drugs, and incarcerated persons, are stored in South Africa despite being on higher risk of HIV acquisition and transmission than the general population. …”
Get full text

Choice regularities of antihypertensive therapy regimens of primary open-angle glaucoma in conditions of real clinical practice by Z.M. Nagornova, A.V. Seleznev, P.Ch. Zavadskiy, A.V. Kuroyedov

“…Kuroyedov^3,4<br> ¹ Ivanovo State Medical Academy, Russian Federation<br> ² High-tech Cataract Treatment Center «New Vision», Minsk, Republic of Belarus<br> ³ Central Military Clinical Hospital named after P.V. …”
Get full text

Effect of Different Doses of Intrathecal Nalbuphine as Adjuvant to Hyperbaric Bupivacaine on Characteristics of Subarachnoid Block in Pelvic and Lower Limb Orthopaedic Surgeries: A... by Anupama Kumari, Shraddha Jogani, Nilesh Shah, Sara Mary Thomas

“…It has less affinity and strength of depressant effects on myocardial and Central Nervous System (CNS) vital centers in pharmacodynamic studies, along with a superior pharmacokinetic profile. …”
Get full text

Diagnostic value of macular blood flow in normal tension glaucoma by A.Sh. Zagidullina, V.U. Galimova, A.I. Arslanova, A.R. Nugmanova

“…All patients underwent OCTA by measuring vascular density (VD, %) using the ETDRS grid (central Fovea and Parafovea) and retinal thick-ness using the Angio Retina 3.0 protocol of the Optovue XR Avanti with the AngioVue function (Optovue, USA). …”
Get full text