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19721
Clinical And Molecular-Genetic Features Of Congenital Aniridia
Published 2018-07-01“…Patients also show other eye structures as well as central nervous system anomalies. AN is caused by heterozygous mutations of the PAX6 gene or chromosome rearrangements of 11p13 region. …”
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19722
An evaluation of the effectiveness of an updated pre-service midwifery curriculum integrated with emergency obstetric and newborn care in Kenya: a cluster randomised controlled tri...
Published 2024-12-01“…Abstract Introduction Quality midwifery education is central to improving midwifery service delivery and maternal and newborn health outcomes. …”
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19723
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation
Published 2025-02-01“…Mass spectrometry revealed a conserved set of proteins including THBS1 (thrombospondin 1), SERPINE1 (serpin family E member 1), ANXA1 (annexin A1), LOX (lysyl oxidase), and ITGB1 (integrin beta-1) which are involved in extracellular matrix (ECM) organization and wound healing, with the PI3K/AKT signaling pathway playing a central role. The PEGDA/SA/Col-I hydrogel demonstrated a unique balance of mechanical and biological properties and an optimal environment for MSC viability and function. …”
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19724
The Croton genera (Euphorbiaceae) and its richness in chemical constituents with potential range of applications
Published 2025-02-01“…Conclusion: This revision has a novel and principal aim: to collect information on the biomedicinal, chemical, and industrial applications of extracts from several species distributed across various regions of the world (Africa, South America, Asia, North America, Central America, and South America), providing an objective evaluation of the relevance of the studies cited here and their suitability for scientific scrutiny and systematic reproduction of the results obtained . …”
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19725
Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia
Published 2025-01-01“…This study aims to explore the depression-like behavior, sleep changes, central oxidative stress response, pineal mitochondrial autophagy damage, melatonin secretion, histopathological changes of the pineal gland, and the expression of Pink1/Parkin signaling-related factors in CUMS+SD rats. …”
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19726
Noninvasive Oral Hyperspectral Imaging–Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study
Published 2025-01-01“…Subsequently, from August 2024 to September 2024, an additional 35 patients were enrolled from Three Gorges University and Yichang Central People’s Hospital to constitute the external testing group. …”
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19727
RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melan...
Published 2025-01-01“…RECQL4, a RecQ‐like helicase, plays a central role in DNA replication and repair as part of the DNA damage response, a pathway implicated in enhancing efficacy of immune checkpoint inhibitor (ICI) therapies. …”
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Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch...
Published 2025-03-01“…Both contribute to significant components of disease burden and health expenditure. Poor bone quality, central obesity, sarcopenia, falls, and low grip strength are independent risk factors for hip and other fragility fractures and also for CVD and early death. …”
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19729
Burden of alopecia areata in China, 1990–2021: Global Burden of Disease Study 2021
Published 2025-02-01“…Slight regional disparities were observed, with the northern and central regions of China bearing comparatively higher burdens. …”
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19730
Evaluation of Performance Metrics Required in Proper Selection of SDN Controller for Integrated Satellite-Terrestrial Networks
Published 2024-09-01“… SDN controllers are increasingly becoming an integral part of modern communication networks due to their ability to centrally control and manage networks from a global point of view. …”
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19731
Physicochemical characterization of biodegradable polymer polyhydroxybutyrate from halophilic bacterium local strain Halomonas elongata
Published 2024-07-01“…This research aimed to develop an environmentally sustainable material for reducing the accumulation of plastic waste in the ecosystem.METHODS: A local bacterial strain from Mud Crater Bledug Kuwu, Grobogan, Central Java, Indonesia, was isolated and identified as Halomonas elongata. …”
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Large range sizes link fast life histories with high species richness across wet tropical tree floras
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Dynamic selectout and voting-based federated learning for enhanced medical image analysis
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