Comprehensive analysis of clinicopathologic and prognostic features in locally advanced thyroid papillary cancer by Liang Jiwang, Ye Dongman, Fang Fengqin, Zhao Yuejiao

“…Compared to EPTC, the proportion of male, bilaterality, multifocality, tumor size > 1 cm, ETE, central lymph node metastasis, and lateral lymph node metastasis was higher in LAPTC (all p < 0.05). …”
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Nesting population trend of the leatherback sea turtle in Bocas del Toro province and Comarca Ngäbe-Buglé, Panama for the period 2002–2022 by Sonia Gutiérrez Parejo, Susan E. Piacenza, Raúl García, Cristina Ordóñez, Roldán A. Valverde

“…Here, we analysed 20 years of annual nest abundance at four main nesting beaches (Soropta, Bluff, Playa Larga and Chiriquí) in Bocas del Toro province and the Comarca Ngäbe-Buglé, Panama, which constitute the largest nesting leatherback sea turtle population in Central America. We conducted daily nest counts during the leatherback season. …”
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Association analysis of suicide risk assessed with Mini International Neuropsychiatric Interviews’ Suicidality Module in adolescents with non suicidal self injury disorder by Shuo Geng, Shuo Geng, Wen Zhang, Xiang Gao, Lele Qu, Xueping Zheng, Jian Sun, Mingdong Xu, Hua Lin, Xueyu Jia, Xu Zhang

“…Network analysis suggests the centrality of anxiety symptoms and father’s education level.ConclusionThe results of statistical analysis suggest that severe depressive symptoms are related to the high risk of suicide (based on MINISM) in adolescents with NSSI-D statistical significantly, and anxiety symptoms and low self-concept are associated with depressive symptoms in NSSI-D adolescents. …”
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PATHOLOGICAL CHANGES IN MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS DNA by E. V. Dolgova, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, S. I. Baiborodin, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. S. Panov, S. N. Zagrebelnyi, M. A. Shurdov

“…Pathological and morphological analyses show that starting from posttreatment day 9, mice that received CP+DNA preparations displayed pronounced morphological changes in their lungs, liver, pancreas, central and peripheral immune system organs, and brain. …”
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Survey of medication history of patients with stroke after discharge from an acute hospital ward: a case series study by Yuko Fukuda, Risa Ito, Misaki Kakihana, Tsutomu Takahashi, Tetsuji Kanemoto, Toshiyuki Sahara, Masahiko Tsujikawa, Mitsuko Onda

“…Based on the medicinal efficacy classification, four patients treated with other blood and body fluids-related agents (antiplatelet drugs), three patients treated with agents for hyperlipidemia (statins), two patients with agents for peptic ulcers, two patients with vasodilators, one patient treated with antihypertensives, and one patient with other agents affecting digestive organs (antiemetic agents that acts on the central nervous system) had discrepancies. Furthermore, discrepancies in medication discontinuation or reduction recommended by a stroke specialist, which may increase the risk of stroke recurrence, were identified in five patients (seven drugs: four antiplatelet drugs and three statins). …”
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Functional differentiation of human dental pulp stem cells into neuron-like cells exhibiting electrophysiological activity by B. Pardo-Rodríguez, A. M. Baraibar, I. Manero-Roig, J. Luzuriaga, J. Salvador-Moya, Y. Polo, R. Basanta-Torres, F. Unda, S. Mato, Gaskon Ibarretxe, Jose Ramon Pineda

“…Abstract Background and aim Human dental pulp stem cells (hDPSCs) constitute a promising alternative for central nervous system (CNS) cell therapy. Unlike other human stem cells, hDPSCs can be differentiated, without genetic modification, to neural cells that secrete neuroprotective factors. …”
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Safety of influenza vaccination during pregnancy: a systematic review by Brian Hutton, David Moher, Danielle B Rice, Claire Butler, Andrea C Tricco, Becky Skidmore, Candyce Hamel, Chantelle Garritty, Paul A Khan, Marco Ghassemi, Charlene Soobiah, Leila Esmaeilisaraji, Dianna M Wolfe, Deshayne Fell, Mona Hersi, Nadera Ahmadzai, Alan Michaud, Angela Sinilaite

“…Objective We conducted a systematic review to evaluate associations between influenza vaccination during pregnancy and adverse birth outcomes and maternal non-obstetric serious adverse events (SAEs), taking into consideration confounding and temporal biases.Methods Electronic databases (Ovid MEDLINE ALL, Embase Classic+Embase and the Cochrane Central Register of Controlled Trials) were searched to June 2021 for observational studies assessing associations between influenza vaccination during pregnancy and maternal non-obstetric SAEs and adverse birth outcomes, including preterm birth, spontaneous abortion, stillbirth, small-for-gestational-age birth and congenital anomalies. …”
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Altered immune surveillance of B and T cells in patients with persistent residual lung abnormalities 12 months after severe COVID-19 by Julio Flores-Gonzalez, Ivette Buendia-Roldan, Fernanda Téllez-Quijada, Carlos Peña-Bates, Lucero A. Ramón-Luing, Armando Castorena-Maldonado, Ramcés Falfán-Valencia, Gloria Pérez-Rubio, Moisés Selman, Leslie Chavez-Galan, Leslie Chávez-Galán

“…Notably, the PLAG group also exhibited higher frequencies of central memory CD4 + Th2 (GATA3+) T-cells in response to activation than the FRG group (p = 0.0079). …”
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Avoidable factors associated with maternal death from postpartum haemorrhage: a national Malawian surveillance study by Arri Coomarasamy, Maria Lisa Odland, Luis Gadama, David Lissauer, Fannie Kachale, Chifundo Ndamala, Abi Merriel, Catriona Waitt, Hussein H Twabi, Annie Kuyere, Marthe Onrust, Jennifer Riches, Yamikani Chimwaza, Rosemary Bilesi, Lumbani Makhaza, Regina Makuluni, Laura Munthali, Owen Musopole, Deborah A Phiri, James Jafali

“…We conducted a detailed review of all maternal deaths from 33 facilities in Malawi to identify health system weaknesses leading to deaths from PPH.Methods Data were collected regarding every maternal death occurring across all district and central hospitals in Malawi. Deaths occurring from August 2020 to December 2022 were reviewed by multidisciplinary facility-based teams who compiled case narratives from clinical notes and then subsequently reviewed by obstetricians to confirm the cause of death according to international criteria. …”
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Intravitreal Injections for Macular Edema Secondary to Retinal Vein Occlusion: Long-Term Functional and Anatomic Outcomes by Emilia Maggio, Maurizio Mete, Giorgia Maraone, Marcella Attanasio, Massimo Guerriero, Grazia Pertile

“…Subsequent retreatment was guided by best-corrected visual acuity (BCVA) and central macular thickness (CMT) measurements, aimed at achieving macular fluid regression and BCVA stability. …”
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A Critical Appraisal of System-Reported Organ Dose (OD) Versus Manually Calculated Mean Glandular Dose (MGD) in Dubai’s Mammography Services by Kaltham Abdulwahid Mohammad Noor, Norhashimah Mohd Norsuddin, Muhammad Khalis Abdul Karim, Iza Nurzawani Che Isa, Vaidehi Ulaganathan

“…<b>Methods</b>: A retrospective study of 2754 anonymized mammograms from six clinics in Dubai were randomly retrieved from a central dose survey database. Organ doses were documented along with other dosimetry information like kVp, mAs, filter, target, compression force, and breast thickness. …”
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Worldwide patterns and trends in ovarian cancer incidence by histological subtype: a population-based analysis from 1988 to 2017Research in context by Yi-Fan Wei, Li Ning, Yi-Lin Xu, Jing Ma, Dong-Run Li, Zan-Fei Feng, Fang-Hua Liu, Yi-Zi Li, He-Li Xu, Peng Li, Yong-Pei Yu, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Chun-Qing Lin, Ting-Ting Gong, Qi-Jun Wu, Jing-He Lang

“…Findings: The incidence of OC displayed marked disparities across regions and Human Development Index (HDI), with the highest ASRs in Eastern and Central Europe and very high HDI regions, and the lowest in Africa, Asia, and medium HDI regions. …”
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Effects of plant active substances in rheumatoid arthritis—a systematic review and network meta-analysis by Qiuwei Peng, Jian Wang, Kesong Li, Congming Xia, Chuanhui Yao, Qiuyan Guo, Xun Gong, Xiaopo Tang, Quan Jiang

“…The widespread use of these extracts as therapeutic measures for RA is problematic due to the lack of compelling evidence.ObjectiveOur research aims to assess the impact of plant active substances on RA by conducting a network meta-analysis.MethodsWe systematically searched four electronic databases—PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, and Web of Science—from their inception to August 2024. …”
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Clinical risk score to predict in-hospital mortality in COVID-19 patients: a retrospective cohort study by Adriano Peris, Andrea Ungar, Niccolò Marchionni, Federico Lavorini, Alessandro Bartoloni, Stefano Fumagalli, Rossella Marcucci, Giulia Cesaroni, Riccardo Pini, Carlo Nozzoli, Carlo Fumagalli, Renzo Rozzini, Matteo Vannini, Flaminia Coccia, Francesca Mazzeo, Maria Cola, Paolo Fontanari, Alessandro Morettini, Filippo Pieralli, Loredana Poggesi

“…In the present study, we aimed to develop a clinical risk score to predict the in-hospital mortality in COVID-19 patients, based on a set of variables available soon after the hospitalisation triage.Setting Retrospective cohort study of 516 patients consecutively admitted for COVID-19 to two Italian tertiary hospitals located in Northern and Central Italy were collected from 22 February 2020 (date of first admission) to 10 April 2020.Participants Consecutive patients≥18 years admitted for COVID-19.Main outcome measures Simple clinical and laboratory findings readily available after triage were compared by patients’ survival status (‘dead’ vs ‘alive’), with the objective of identifying baseline variables associated with mortality. …”
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Analysis of the structure and function of the tomato <i>Solanum lycopersicum</i> L. MADS-box gene <i>SlMADS5</i> by A. V. Nezhdanova, M. A. Slugina, E. A. Dyachenko, A. M. Kamionskaya, E. Z. Kochieva, A. V. Shchennikova

“…The E-proteins SEPALLATA are the central hub of the MADS-complexes, which determine the identity of the floral organs. …”
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Estrategia educativa de intervención en enfermería encaminada al cuidado de los niños con ventilación mecánica en el domicilio by Felicia Rodríguez Solís, Zulema Sánchez Acosta, Jayce Díaz Díaz, Lourdes Hernández Pujol, Caridad Stuart Gandulla, Miguelina Rodríguez Solís

“…<br /><strong>Objetivo:</strong> diseñar una estrategia educativa que integre los distintos niveles de atención en salud, encaminada al cuidado de los niños con ventilación mecánica en el domicilio, teniendo como eje central la familia y su entorno.<br /> <strong>Métodos:</strong> investigación realizada en la Unidad de Cuidados Intensivos del Hospital Pediátrico Universitario Paquito González Cueto y el Policlínico Universitario Cecilio Ruiz de Zarate, de Cienfuegos, durante los años 2015 – 2016. …”
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Understanding Loneliness in an Aging Population of San Vito de Coto Brus, Costa Rica by Nicholas Leahy, Melissa Rallo, Lillianna Pedersen, Christine Wan, Hima Konduru, Shania Bailey, Alexis Vetack, Wendel Mora, Shailvi Gupta, Carlos Faerron Guzmán

“…While loneliness has been studied in a few communities around the world, there is a need to study loneliness in the context of Latin American communities in Central America, including Costa Rica. The aim of the present study is to assess the prevalence and associated factors of social and emotional loneliness (SEL) in a sample of elderly patients in the canton of Coto Brus, Costa Rica. …”
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Inequalities in ownership and availability of home-based vaccination records in 82 low- and middle-income countries by Aluísio J D Barros, Cesar G Victora, Daniel R Hogan, M Carolina Danovaro-Holliday, Bianca O Cata-Preta, Thiago M Santos, Andrea Wendt, Luisa Arroyave, Tewodaj Mengistu

“…The lowest percentages of HBRs seen were in Kiribati (22.1%), the Democratic Republic of Congo (24.5%), Central African Republic (24.7%), Chad (27.9%) and Mauritania (35.5%). …”
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Corneal Cap Thickness and Its Effect on Visual Acuity and Corneal Biomechanics in Eyes Undergoing Small Incision Lenticule Extraction by Ting Liu, Ting Yu, Lina Liu, Kaijian Chen, Ji Bai

“…The patients with 510 μm–560 μm central corneal thickness (CCT) and a refractive spherical equivalent of −3.00 D to −8.00 D were included. …”
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COVID-19 is a risk factor for retinal vein occlusion in younger patients? by A.G. Shchuko, M.V. Akulenko, T.N. Yur’eva

“…Clinical criteria of escalating retinal ischemia are decreased central visual acuity, macular edema, increased area of ischemia, and (later) retinal and/or anterior segment neovascularization. …”
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