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18761
Comparison of Illumina and Oxford Nanopore sequencing data quality for Clostridioides difficile genome analysis and their application for epidemiological surveillance
Published 2025-01-01“…Molecular and virulence genotyping are central for the epidemiological surveillance of this pathogen, but need to balance accuracy and rapid turnaround time of the results. …”
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18762
Bone marrow mesenchymal stem cells derived cytokines associated with AKT/IAPs signaling ameliorate Alzheimer’s disease development
Published 2025-01-01“…The specific mechanism and central role of cytokines in this process have not been fully elucidated. …”
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18763
Catastrophe Mechanism of Stress-Fissure Coupling Field in Mining Close Distance Seams in Southwest China
Published 2021-01-01“…When the working face advances to 180 m in 4# coal seam in a similar experiment, the overlying rock breaks to the central base plate of Yulongshan limestone, and the conductive fractures run through the Changxing limestone karst cave and Yulongshan limestone karst cave. …”
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18764
One Health preparedness and response for mosquito-borne viruses: a stakeholder- and social network-analysis in the Netherlands
Published 2025-01-01“…We recommend utilising existing collaborations, identified in this study, and central stakeholders to overcome these bottlenecks.…”
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18765
Machine learning-based plasma metabolomics for improved cirrhosis risk stratification
Published 2025-02-01“…Pathway enrichment analysis revealed that disruptions in lipid and amino acid metabolism play a central role in the progression of cirrhosis. Conclusion 1 H-NMR serum metabolomics significantly improves the prediction of cirrhosis risk in patients with CLD. …”
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18766
Impact of muscle fatigue on anticipatory postural adjustments during gait initiation
Published 2025-01-01“…Altogether, these results support the idea that one and the same person may develop a repertoire of postural strategies among which the central nervous system will choose, according to the personal fitness and the constraints in which the action is performed.…”
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18767
Accommodative Exercises to Lower Intraocular Pressure
Published 2020-01-01“…Baseline measurements of central cornea thickness, anterior chamber depth, anterior chamber angle, cornea diameter, pupil size, and ciliary muscle thickness were made by autorefraction and optical coherence tomography (OCT), while IOP was measured by pneumotonometry. …”
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18768
A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions
Published 2025-01-01“…The OMICS task force recommended an integrated, longitudinal, simultaneous systems biology study of participant biospecimens on the entire RECOVER cohorts through centralized laboratories, as opposed to multiple smaller studies using one or few analytical techniques. …”
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18769
The Timing of Infarction Pain in Patients with Acute Myocardial Infarction after Previous Revascularization
Published 2008-01-01“…This subgroup of patients, together with the subgroups of patients with a dominant evening peak (patients with CHF and those with non-STEMI) and with patients with no peak (patients with previous angina and previous AMI), probably appear to modify characteristic circadian variation of infarction onset, expressing a higher evening peak, respectively to the previous CABG, with adverse consequences for central nervous system functioning.…”
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18770
Análisis multidimensional de la voz en usuarios con enfermedad de Parkinson: Un estudio de casos
Published 2025-01-01“… La enfermedad de Parkinson (EP) es una patología neurodegenerativa que afecta el sistema nervioso central, caracterizada por manifestaciones clínicas motoras y no motoras. …”
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18771
Impacto de una solución para el estudio de vías de conducción nerviosa en Morfofisiología III
Published 2013-07-01“…Se utilizó un conjunto de modelos tridimensionales que simulan estructuras del sistema nervioso central a gran escala con la mayor cantidad de detalles anatómicos que pudieron representarse. …”
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18772
Cannabis related side effects in otolaryngology: a scoping review
Published 2021-09-01“…Methods The Preferred Reporting Items For Systematic Reviews and Meta-analysis extension for Scoping Reviews (PRISMA-ScR) protocol was used to conduct a scoping review of the MEDLINE, EMBASE, CINAHL, and CENTRAL databases. (PROSPERO: CRD42020153022). English studies in adults were included from inception to the end of 2019. …”
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18773
Nose-to-Brain Delivery of Chitosan-Grafted Leciplexes for Promoting the Bioavailability and Antidepressant Efficacy of Mirtazapine: In Vitro Assessment and Animal Studies
Published 2025-01-01“…<b>Methods</b>: Primarily, MRZ-loaded leciplexes (MRZ-LPXs) were fabricated and tailored employing a central composite design (CCD). Vesicle diameter size (VS), entrapment efficiency (EE %), cumulative MRZ release percentage (CMRZR %), and total quantity penetrating after twenty-four hours (Q24) were the four parameters assessed. …”
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18774
Predicting the Global Distribution of <i>Nitraria</i> L. Under Climate Change Based on Optimized MaxEnt Modeling
Published 2024-12-01“…The <i>Nitraria</i> L. plants are currently found mainly in Central Asia, North Africa, the neighboring Middle East, and parts of southern Australia and Siberia. …”
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18775
Prediction of Causative Genes in Inherited Retinal Disorders from Spectral-Domain Optical Coherence Tomography Utilizing Deep Learning Techniques
Published 2019-01-01“…Horizontal/vertical cross-sectional scans of optical coherence tomography (SD-OCT) at the central fovea were cropped/adjusted to a resolution of 400 pixels/inch with a size of 750 × 500 pix2 for learning. …”
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18776
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18777
COVID-19 Vaccines Effectiveness and Safety in Trinidad and Tobago: A Systematic Review and Meta-Analysis
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18778
Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomizatio...
Published 2025-01-01“…Moreover, bidirectional Mendelian randomization analyses provide supporting evidence for a potential causal relationship between TET2-related CHIP and the development of T2DM. Graphical abstract Central Illustration: The association between clonal hematopoiesis of indeterminate potential (CHIP) and type 2 diabetes mellitus (T2DM): The prevalence of CHIP is notably higher in individuals with T2DM, as demonstrated in a prospective study within an Asian cohort of acute myocardial infarction (AMI). …”
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18779
Adaptive responses of large-seeded lentils across diverse Indian climates
Published 2025-02-01“…For this, diverse sets of large-seeded lentil genotypes were tested across multiple locations spanning three agroclimatic zones of India: North Hill Zone (NHZ), North Western Plain Zone (NWPZ), and Central Zone (CZ). Substantial variability was observed in days to flowering (53–147 days), maturity duration (87–200 days), reproductive period (33–65 days), grain yield (0.77–2.18 t ha−1), and 100-seed weight (2.3–4.5 g) across locations. …”
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18780