Treatment of neovascular age-related macular degeneration: one year real-life results with intravitreal Brolucizumab by Settimio Rossi, Carlo Gesualdo, Ernesto Marano, Raffaele Perrotta, Maria Consiglia Trotta, Antonio Del Giudice, Francesca Simonelli

“…Monthly, all participants underwent comprehensive ophthalmological evaluation until 12 months follow-up.ResultsWe observed a significant improvement in best corrected visual acuity (39 ± 15 L vs. 30 ± 17 L; p < 0.01) and central retinal thickness (265 ± 89 μ vs. 360 ± 129 μ; p < 0.0001) at the end of follow-up without any differences between treatment-naïve and non-naïve patients. …”
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‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: e... by Joseph Rujumba, Carmen Roebersen, Susan Namara, Richard Ochen, Sharon Eva Ahumuza, Allen Tushabe, Mathias Akugizibwe, David Bitira, Innocent Mwesigye, Stella Kentusi, Henry Zakumumpa, Japheth Kwiringira, Merian Natukwatsa Musinguzi

“…Aidsfonds and partners in Uganda implemented an eight-year ‘Towards an AIDS Free Generation in Uganda’ (TAFU) programme in central, western and eastern, Uganda with Village Savings and Loan Associations (VSLAs) as a key component. …”
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Impact of Physical Features on Visual Walkability Perception in Urban Commercial Streets by Using Street-View Images and Deep Learning by Gonghu Huang, Yiqing Yu, Mei Lyu, Dong Sun, Bart Dewancker, Weijun Gao

“…Urban commercial streets are a crucial component of urban life, serving as the central hubs of commercial activity and providing vital spaces for both residents and visitors to engage in various activities. …”
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Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study by Malik Sallam, Tleen Kherfan, Amwaj Al‐Farajat, Leen Nemrawi, Nada Atawneh, Rand Fram, Ala'a B. Al‐Tammemi, Muna Barakat, Kamil Fram

“…Methods Face‐to‐face interviews were conducted in obstetrics/gynecology clinics in the Central, Northern, and Southern regions of Jordan during January–February 2024, using a convenience sampling approach. …”
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Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind... by Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod, Areepan Sophonsritsuk

“…Nefopam is a non-NSAIDs and opioid sparing centrally acting drug which is effective for a multimodal postoperative analgesia. …”
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Developmental dysfunction in a preclinical model of Kcnq2 developmental and epileptic encephalopathy by Miaomiao Mao, Nikola Jancovski, Yafit Kushner, Lucas Teasdale, Phan Truong, Kun Zhou, Samuel Reid, Linghan Jia, Ye Htet Aung, Melody Li, Christopher A. Reid, Sean Byars, Ingrid Scheffer, Steven Petrou, Snezana Maljevic

“…KCNQ2 encodes a voltage-gated potassium channel KV7.2 widely expressed in the central nervous system and critically involved in the regulation of neuronal excitability. …”
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An updated network meta-analysis of non-pharmacological interventions for primary hypertension in adults: insights from recent studies by Ziwen Chen, Qifu Li, Tao Xu, Xueli Zhou, Yunjie Shu, Taipin Guo, Fanrong Liang

“…We conducted a thorough search in eight databases, including PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database, CNKI, WanFang Data, and Chongqing VIP, identifying potential randomized controlled trials (RCTs) from January 1, 2013, to August 1, 2024. …”
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Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands by Wanderson Ferreira da Silva Júnior, Karen Marques de Oliveira Costa, Hortência Maciel Castro Oliveira, Maísa Mota Antunes, Kassiana Mafra, Brenda Naemi Nakagaki, Pedro Sérgio Corradi da Silva, Júlia Duarte Megale, Sarah Campos de Sales, Douglas Carvalho Caixeta, Mário Machado Martins, Robinson Sabino-Silva, Cristina Maria Pinto de Paula, Luiz Ricardo Goulart, Rafael Machado Rezende, Gustavo Batista Menezes

“…The liver plays a central role in fat storage, but little is known about physiological fat accumulation during early development. …”
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From across the globe – traumatic injuries are an international concern at the US-Mexico border wall by Allison E Berndtson, Jay Doucet, Todd W Costantini, Laura Haines, Sarah Lagan, Laura Adams, Jarrett Santorelli, Gabriella Waters

“…When considering regions of the world other than Mexico, patients were most commonly from Africa, South America and Central America.Conclusion The increased volume of trauma associated with the US-Mexico border wall is a humanitarian and health crisis.(1) The diverse national origin of patients admitted after injury from border wall falls has shed new light on the social and interpreter services needed to care for these border injury patients and the challenges that exist in their post-discharge care.…”
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Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers by Lothar Häberle, Ramona Erber, Paul Gass, Alexander Hein, Melitta Niklos, Bernhard Volz, Carolin C. Hack, Rüdiger Schulz-Wendtland, Hanna Huebner, Chloë Goossens, Matthias Christgen, Thilo Dörk, Tjoung-Won Park-Simon, Andreas Schneeweiss, Michael Untch, Valentina Nekljudova, Sibylle Loibl, Arndt Hartmann, Matthias W. Beckmann, Peter A. Fasching

“…The higher the pCR-prob, the greater the prognostic impact of pCR status (presence/absence): hazard ratios decreased from 0.55 (95% central range, 0.07–1.77) at 0% to 0.20 (0.11–0.31) at 50% pCR-prob. …”
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Long-Term Destiny of Corneal Endothelial Cells in Anterior Chamber Intraocular Lens-Implanted Eyes by Yating Tang, Jie Xu, Jiahui Chen, Yi Lu

“…Follow-up outcomes included the best-corrected visual acuity (BCVA), endothelial cell density, hexagonality, coefficient of variance, and central corneal thickness. Results. In total, 23 eyes (62.16%) with phakic and 14 eyes (37.84%) with aphakic AC-IOLs were included. …”
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Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins by Anna-Sophia Hartke, Cara S. Schreiber, Kristina Lau, Ivo Wiesweg, Inken Waltl, Ulrich Kalinke, Franziska Richter, Christopher Käufer

“…In conclusion, aSyn pathology renders the peripheral and central immune response more sensitive to a single low dose of bacterial endotoxin, which mimics a transient dysbiosis or gut infection. …”
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The Role of Cardiac Resynchronization Therapy in Heart Failure: A Narrative Review by Olivier Uwishema, Ece Karabulut, Dalal Sheikhah, Burhan Kantawala, Misgana Gallo, Fatima Soufan, Magda Wojtara

“…Methods An extensive review of the literature was conducted with evidence from several databases like Medline, PubMed Central, and Embase. Preference was given to articles published after 2010, but relevant articles even pre‐2010 were included. …”
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Serological Evidence of Infectious Laryngotracheitis Infection and Associated Risk Factors in Chickens in Northwestern Ethiopia by Mastewal Birhan, Ashenafi Syoum, Saddam Mohammed Ibrahim, Tewodros Fentahun, Addisu Mohammed, Nega Berhane, Molalegne Bitew, Esayas Gelaye, Malede Birhan Atanaw, Belayneh Getachew, Bereket Dessalegn, Anmaw Shite Abat, Kassahun Berrie, Kassaye Adamu, Takele Abayneh

“…A cross-sectional study was conducted from November 2020 to June 2021 in three selected zones of the Amhara region (Central Gondar, South Gondar, and West Gojjam zones), Ethiopia, with the objective of estimating the seroprevalence of ILTV in chickens and identifying and quantifying associated risk factors. …”
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Innovator ranibizumab ComparEd to Biosimilar ranibizumab in combination with Expansile gas in submaculaR HemorrhaGe: the ICEBERG study by Debdulal Chakraborty, Tushar Kanti Sinha, Soumen Mondal, Subhendu Boral, Arnab Das, Saptorshi Majumbar, Angshuman Mukherjee, Ranabir Bhattacharya, Sumit Randhir Singh

“…Changes in best corrected visual acuity (BCVA) and central macular thickness (CMT) were assessed at 6 months. …”
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A Survey of Differential Privacy Techniques for Federated Learning by Wang Xin, Li Jiaqian, Ding Xueshuang, Zhang Haoji, Sun Lianshan

“…Over the years, differential privacy technology based on federated learning framework has been developed, which is divided into central differential privacy federated learning(CDPFL) and local differential privacy federated learning(LDPFL). …”
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Professional Barriers in Energy Efficiency Retrofits—A Solution Based on Information Flow Modeling by Xilong Liao, Chun Wang, Baiyi Li, Baizhan Li, Chenqiu Du

“…These findings highlight that knowledge gaps and information asymmetry are the central challenges. To tackle these issues, this paper suggests the implementation of an information flow model that integrates the IDEF0 and DSM for building energy-saving retrofit projects. …”
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Concept of a geoinformation platform for landmines and other explosive objects detection and mapping with UAV by Mykhailo Popov, Sergey Stankevich, Sergey Mosov, Stanislav Dugin, Stanislav Golubov, Artem Andreiev, Artur Lysenko, Ievgen Saprykin

“…The methods used are remote sensing, automated object detection, and centralized data processing in a geographic information system (GIS). …”
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We Walk: a person-centred, dyadic behaviour change intervention to promote physical activity through outdoor walking after stroke—an intervention development study by Stephan U Dombrowski, Brendan McCormack, Maggie Lawrence, Frederike Van Wijck, Jacqui H Morris, Linda A Irvine

“…Phase 2 review by stakeholder focus groups and behaviour change experts endorsed intervention components and structure, emphasising dyadic relational aspects as central to potential success. In phase 3, intervention content and handbooks for PWS and buddies were finalised. …”
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Effect of Prior Bariatric Surgery on the Outcomes of Joint Arthroplasty: A Systematic Review and Meta-Analysis by Zhou Zhang, Xiang Shi, Wei Liu, Jianwei Wang, Qingfeng Shen, Guozhu Xu, Jiakuan Bao, Yupeng Dong

“…With this systematic review and meta-analysis, we assessed whether a positive history of bariatric surgery influences postoperative outcomes in patients undergoing various types of joint arthroplasty.Methods We conducted a comprehensive search database such as Scopus, PubMed, Medline Ovid, CNKI, and CENTRAL for studies comparing outcomes between patients undergoing arthroplasty with and without a history of bariatric surgery. …”
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