A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2– Metastatic Breast Cancer by Elizabeth J. Anderson, Lea E. Mollon, Joni L. Dean, Terri L. Warholak, Ayal Aizer, Emma A. Platt, Derek H. Tang, Lisa E. Davis

“…A comprehensive search of PubMed/MEDLINE, EMBASE, Cochrane Central, and select conference abstracts (i.e., AACR, ASCO, SABCS, ECCO, and ESMO conferences between 2014 and 2017) identified 39 studies of patients with HR+, HER2– mBC. …”
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Percutaneous Mitral Valve Repair versus Optimal Medical Therapy in Patients with Functional Mitral Regurgitation: A Systematic Review and Meta-Analysis by Muhammad Uzair Lodhi, Muhammad Shariq Usman, Tariq Jamal Siddiqi, Muhammad Shahzeb Khan, Muhammad Arbaz Arshad Khan, Safi U. Khan, Intekhab Askari Syed, Mustafa Rahim, Srihari S. Naidu, Rami Doukky, Mohamad Alkhouli

“…We performed a systematic review and a meta-analysis to address this question. Cochrane CENTRAL, MEDLINE, and Scopus were searched for randomized (RCT) and nonrandomized studies comparing PMVR with OMT in patients with HF and FMR. …”
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Analysis of retinal sublayers in patients with systemic COVID-19 illness with varying degrees of severity by Mohammad Reza Talebnejad, Mohammad Reza Badie, Hossein Shahriari, M. Hossein Nowroozzadeh

“…Spectralis SD-OCT scans of the macula and optic nerve were obtained from all participants 6 weeks after initial diagnosis. The central subfield thickness of the macula (CSFT), peripapillary retinal nerve fiber layer thickness (pRNFL), and retinal sublayers’ volumes in the total 6-mm ETDRS zone were recorded and analyzed using the ANCOVA test, adjusting for age. …”
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Identification of biomarkers associated with coronary artery disease and non-alcoholic fatty liver disease by bioinformatics analysis and machine learning by Chuan Lu, Mei Han, Qiqi Ma, Li Ying, Yue Zhang

“…Protein–protein interaction (PPI) network was constructed with common DEGs (co-DEGs), and hub genes were screened by Maximal Clique Centrality (MCC) algorithm. Candidate biomarkers were selected from intersection of three machine learning algorithms. …”
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Modified sutureless and glue-free method versus conventional sutures for conjunctival autograft fixation in primary pterygium surgery: a systematic review and meta-analysis by Faisal Aljahdali, Waleed Khayyat, Abdulelah T BinYamin, Sultan A Al-Qahtani, Mohammed D Alghamdi, Ali Saleh Alsudais, Husain A Alalgum, Halah Bin Helayel, Mohammed AlMutlak

“…This systematic review and meta-analysis compared the modified sutureless glue-free (MSGF) method with conventional sutures (CS) for conjunctival autograft fixation in primary pterygium surgery.Methods A comprehensive search was conducted in MEDLINE, Embase, CENTRAL, Google Scholar and ClinicalTrials.gov for randomised controlled trials (RCTs) comparing MSGF and CS conjunctival autografts. …”
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Sustainable pectin extraction from Riang husk using ultrasound-assisted extraction with deep eutectic solvents and its potential in antipollution products by Manee Saelee, Hla Myo, Nuntawat Khat-udomkiri

“…This study investigates the use of ultrasound-assisted extraction (UAE) combined with deep eutectic solvents (DESs) as a sustainable and efficient method for optimizing pectin extraction from Riang husks through the evaluation of a central composite design (CCD), and the structural, functional, and rheological characteristics of the extracted pectin. …”
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SUGT1 is a prognostic biomarker and is associated with immune infiltrates in ovarian cancer by Linyan Ge, Xiu Liu, Lingyan Zhang, Jiaren Zhang, Guanghui Song

“…Besides, ssGSEA demonstrated a positive correlation between SUGT1 expression and the abundance of T central memory cells, natural killer cells, and T gamma delta cells, although it showed a negative association with activated dendritic cells, cytotoxic cells, T cells, and T helper 1 cells. …”
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Neurofilament light chain (Nf-L) in cerebrospinal fluid and serum as a potential biomarker in the differential diagnosis of neurological diseases in cattle by Giorgia Di Muro, Carlotta Tessarolo, Giulia Cagnotti, Alessandra Favole, Sara Ferrini, Ugo Ala, Claudio Bellino, Giuliano Borriello, Marina Gallo, Giulia Iamone, Barbara Iulini, Marzia Pezzolato, Cristina Casalone, Maria Caramelli, Lorenzo Capucci, Patrizia Cavadini, Cristiano Corona, Antonio D’Angelo

“…CSF Nf-L levels were higher in samples from animals with degenerative (median Nf-L 49971 pg/mL) and infectious central nervous system (CNS) disorders (median Nf-L, age < 2 months 8863 pg/mL; age 2–12 months 17474 pg/mL; age 1–6 years 3546 pg/mL), CNS anomalies and metabolic/toxic disorders. …”
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Epidemiology and clinical features of childhood malignant solid tumors in a single center in southwest China over 24 years by Ting Li, Xiangpan Kong, Dawei He

“…The top 3 malignant solid tumors by incidence rate were central nervous system (CNS) tumors (21.8%), neuroblastoma (17.8%), and lymphoma (13.9%). …”
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Goal attainment scaling as an outcome measure for randomised controlled trials: a scoping review by Elaine Pascoe, Andrea Viecelli, Ruth Hubbard, Benignus Logan, Dev Jegatheesan

“…Objectives (1) Identify the healthcare settings in which goal attainment scaling (GAS) has been used as an outcome measure in randomised controlled trials. (2) Describe how GAS has been implemented by researchers in those trials.Design Scoping review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews approach.Data sources PubMed, CENTRAL, EMBASE and PsycINFO were searched through 28 February 2022.Eligibility criteria English-language publications reporting on research where adults in healthcare settings were recruited to a randomised controlled trial where GAS was an outcome measure.Data extraction and synthesis Two independent reviewers completed data extraction. …”
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Taenia solium Cysticercosis and Taeniosis Reporting in the Current Medical and Veterinary Diseases Reporting Systems in Tanzania: A Cross-Sectional Study by Fredy Mlowe, James Mlangwa, Ernatus Mkupasi, Andrea S. Winkler, Antony D. Nyerere, Ayubu Churi, Helena Ngowi, Esron Karimuribo

“…We conducted a cross-sectional study between January and April 2020 in Babati and Mbulu districts (northern Tanzania), Kongwa district (central Tanzania), Mbinga and Nyasa districts (southern Tanzania), and the Zonal Veterinary Centres in Iringa (southern Tanzania) and Arusha (northern Tanzania) regions. …”
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The role of olfactory transport in the penetration of manganese oxide nanoparticles from blood into the brain by A. V. Romashchenko, M. B. Sharapova, К. N. Morozova, E. V. Kiseleva, K. E. Kuper, D. V. Petrovskii

“…It is assumed that NPs can penetrate from blood into the central nervous system (CNS) only by breaking the blood–brain barrier (BBB). …”
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Association of iron deposition in MS lesion with remyelination capacity using susceptibility source separation MRI by Hyeong-Geol Shin, Woojun Kim, Jung Hwan Lee, Hyun-soo Lee, Yoonho Nam, Jiwoong Kim, Xu Li, Peter C.M. van Zijl, Peter A. Calabresi, Jongho Lee, Jinhee Jang

“…Objectives: Susceptibility source-separation (χ-separation) MRI provides in-vivo proxy of myelin (diamagnetic susceptibility, χdia) and iron concentrations (paramagnetic susceptibility, χpara) in the central nervous system, potentially uncovering myelin- and iron-related pathology in multiple sclerosis (MS) lesions (e.g., demyelination, remyelination, and iron-laden microglia/macrophages formation). …”
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Response surface methodology for the design of malachite green dye removal by γ-Fe2O3 dispersed on reduced graphene oxide sheets by Liu Zhu, Anam Sana, Muhammad Tariq Qamar, Ali Bahadur, Guocong Liu, Mohammad Aslam, Ammar Zidan, İsmail Seçkin Çardaklı, Shahid Iqbal, Sajid Mahmood, Muhammad Saad, Khalid M. Alotaibi

“…To minimize experiments and optimize adsorption parameters for the removal of MG by the nanocomposite at 25 °C, central composite design (CCD) using response surface methodology (RSM) was used. …”
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First detection and molecular characterization of Jingmen tick virus with a high occurrence in Rhipicephalus (Boophilus) microplus collected from livestock in Cameroon (2024) by Paloma Kiwan, Eva Lopez, Morena Gasparine, Geraldine Piorkowski, Agathe Colmant, Achille Paguem, Stephanie Mvodo, Laurence Thirion, Xavier de Lamballerie, Remi Charrel, Alessandra Falchi

“…Ticks were collected from cattle and sheep in six sampling sites in an area approximately 30 km long and 18 km wide along the Nyong River, in central Cameroon. Ticks were identified morphologically and molecularly. …”
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A systematic literature review to evaluate the cardiac and cerebrovascular outcomes of patients with Fabry disease treated with agalsidase Beta by Gavin Y. Oudit, Gavin Y. Oudit, Pronabesh DasMahapatra, Nicole Lyn, Florence R. Wilson, Adekemi Adeyemi, Chae Sung Lee, Ana Crespo, Mehdi Namdar

“…Studies were identified in searches of MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials from January 2000–June 2022. …”
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INDEPENDENCE AND FINANCIAL EXPERTISE OF AUDIT COMMITTEE ON VOLUNTARY DISCLOSURE OF DEPOSIT MONEY BANKS IN NIGERIA by Saidu MUSA, Muhammed Kamaldeen Usman, Paul B. Ogunwole

“…., 2008 marked two years after the Central Bank of Nigeria CBN’s ₦25bn recapitalisation policy which made Nigerian banks more financially sound through mergers and acquisition. 2018 was also the latest year to which the annual reports of these banks were made available for public access. …”
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Predictive factors of thrombosis during autologous stem cell transplantation in multiple myeloma: Experience from EHU Oran (Algeria) by Mohammed Amine BEKADJA, Brahim BENZINEB, Mansour BELKACEM, Hafida OUDJERIOUAT, Badra ENTASOLTAN, Soufi OSMANI, Kamila AMANI, Samira BOUCHAMA, Leila CHAREF, Mohamed BRAHIMI, Abdessamad ARABI, Rachir Amar BOUHASS, Nabil YAFOUR

“…Thepredictive factors studied are: age, co-morbidities, use of IMiDs, use of Granocyte colony stimualing factor in mobilization, the central venous catheter insertion site, cytapheresis count, CD34+ perfused, and finally deep venous thrombosis prophylaxis by a low molecular weight heparin .The statistical analysis focused on a univariate study, followed by a multivariate analysis using binary logistic regression. …”
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The Role of Endogenous Beta-Endorphin and Enkephalins in the Crosstalk Between Ethanol and Morphine by Andy Tseng, Syed Muzzammil Ahmad, Abdul Hamid, Kabirullah Lutfy

“…On the test days, mice were placed in the central chamber and allowed to explore the chambers. …”
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Multi-Timescale Battery-Charging Optimization for Electric Heavy-Duty Truck Battery-Swapping Stations, Considering Source–Load–Storage Uncertainty by Peijun Shi, Guojian Ni, Rifeng Jin, Haibo Wang, Jinsong Wang, Zhongwei Sun, Guizhi Qiu

“…With the widespread adoption of renewable energy sources like wind power and photovoltaic (PV) power, uncertainties in the renewable energy output and the battery-swapping demand for electric heavy-duty trucks make it challenging for battery-swapping stations to optimize battery-charging management centrally. Uncoordinated large-scale charging behavior can increase operation costs for battery-swapping stations and even affect the stability of the power grid. …”
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