Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer’s Disease Patients by Vladimira Durmanova, Juraj Javor, Zuzana Parnicka, Gabriel Minarik, Agata Ocenasova, Barbora Vaseckova, Veronika Reznakova, Maria Kralova, Tomas Hromadka, Ivana Shawkatova

“…Alzheimer’s disease (AD) is a chronic neurodegenerative disease of the central nervous system with higher prevalence in elderly people. …”
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Comprehensive analysis of the prognostic, immunological, and diagnostic roles of SIRT1 in pan-cancer and its validation in KIRC by Qi Liu, Songxian Sun, Chunxiang Zhou, Houxi Xu, Houxi Xu

“…In most cancer types, increased SIRT1 expression is positively associated with eosinophils, helper T cells, central memory T cells, effector memory T cells, γδ T cells, and Th2 cells. …”
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Improving the Competitiveness of the Leading Universities of the North Caucasus Federal District in Sync with the Objectives of Regional Development by D. V. Petrosyants, V. V. Zubenko, P. S. Seleznev, I. V. Arzhanova

“…The absence of status universities in the North Caucasus Federal District, in particular a flagship university, contributes to the outflow of talented students to central Russian and foreign universities.Application area. …”
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Complex treatment approach to primary open-angle glaucoma: focus on neuroprotection by M. Kh. Khubetsova, V.V. Kadyshev, B.F. Ambalova

“…Fedorov NMRC “MNTK “Eye Microsurgery”, Moscow, Russian Federation</b> </p> <p> <b>²Moscow Genetic Research Center, Moscow, Russian Federation</b> </p> <p> <b>³Right-Shore Central Regional Clinical Hospital, Beslan, Russian Federation</b> </p> <p> <i>According to the WHO, glaucoma is now the second leading cause of blindness globally. …”
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Minimizing the Diagnostic Delay in Amyotrophic Lateral Sclerosis: The Role of Nonneurologist Practitioners by Martin Matharan, Stéphane Mathis, Sarah Bonabaud, Louis Carla, Antoine Soulages, Gwendal Le Masson

“…The rapid execution of useful additional tests by the first medical doctor, often GP (with the help of a neurologist), considerably reduces the diagnostic delay. The central role of GP seems to be crucial in the management of patients with ALS. …”
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Blood molecular subtypes to guide precision treatment strategies in systemic juvenile idiopathic arthritis by In-Woon Baek, Jung Woo Rhim, Kyung-Su Park, Ki-Jo Kim

“…Gene expression profiles were filtered for differentially expressed genes and unsupervised clustering, gene set enrichment, and network-based centrality analyses. The molecular signatures of three novel sJIA subgroups (designated as C1, C2, and C3) were investigated, focusing on their distinct features and treatment responses. …”
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Condiciones de valoración y posicionamiento de las humanidades en entornos científicos periféricos nacionales: caso estado de Chihuahua (México) by Jesi Pérez-Rivera, Javier Tarango, Fidel González-Quiñones

“…Para demostrar tal condición se generó un modelo teórico simplificado nombrado “Ecosistema de valoración de la comunicación científica en humanidades en el estado de Chihuahua” en cuatro dimensiones: (1) condiciones de generación de conocimiento en revistas científicas mexicanas de humanidades, (2) identificación de entornos geográficos nacionales periféricos y centrales en humanidades, (3) realidad de la comunicación científica de investigadores en humanidades y (4) visión cualitativa de los investigadores. …”
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Decade-Long Analysis: Unravelling the Spatio-Temporal Dynamics of PM10 Concentrations in Malaysian Borneo by Salwa Naidin, Justin Sentian, Farrah Anis Fazliatul Adnan, Franky Herman, Siti Rahayu Mohd Hashim

“…The study divided Sabah and Sarawak into three regions: Northern Malaysian Borneo, Central Malaysian Borneo, and Southern Malaysian Borneo. …”
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The Role of Phosphatidylethanolamine-N-methyltransferase (PEMT) Gene rs12449964 Polymorphism in the Development of Acute Pancreatitis and its Complications by T. A. Samgina, Yu. E. Azarova, Yu. V. Kanishchev, V. A. Lazarenko, P. M. Nazarenko, A. V. Polonikov

“…To determine the role of PEMT C/T rs12449964 polymorphism in the risk of developing acute pancreatitis and its complications among Russian residents in Central Russia.Materials and methods. Whole blood samples were collected from 502 unrelated patients with acute non-biliary pancreatitis (97 women and 405 men) of Russian nationality who had been admitted to the surgical departments of the city of Kursk from 2015 to 2018, as well as from 513 unrelated individuals of Russian nationality without gastrointestinal diseases (101 women and 412 men). …”
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Investigation on Influences of  Two Discrete Methods on Galloping Characteristics of Iced Quad Bundle Conductors by Xiaohui Liu, Guangyun Min, Chuan Wu, Mengqi Cai

“…Secondly, based on the wind tunnel test, the three-component aerodynamic coefficients of each subconductor of the iced quad conductor are obtained, and the equivalent aerodynamic coefficients at the central axis of the quad bundle conductor are obtained by using a reasonable method. …”
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Machine learning-based analysis of sea fog’s spatial and temporal impact on near-miss ship collisions using remote sensing and AIS data by Dan Liu, Ling Ke, Zhe Zeng, Zhe Zeng, Shuo Zhang, Shanwei Liu, Shanwei Liu

“…While its impact is less severe in the central Bohai Sea due to the open waters. Temporally, the contribution of sea fog to near-miss collisions is more pronounced in fall and winter, while it is lowest in summer. …”
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Association between Visual Acuity and Retinal Layer Metrics in Diabetics with and without Macular Edema by LakshmiPriya Rangaraju, Xuejuan Jiang, J. Jason McAnany, Michael R. Tan, Justin Wanek, Norman P. Blair, Jennifer I. Lim, Mahnaz Shahidi

“…Enface thickness maps and reflectance images of the nerve fiber layer (NFL), combined ganglion cell and inner plexiform layer (GCLIPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), photoreceptor outer segment layer (OSL), and retinal pigment epithelium (RPE) were generated in the central macular subfield. The associations among VA and retinal layer metrics were determined by multivariate linear regressions after adjusting for covariates (age, sex, race, HbA1c, diabetes type, and duration) and correcting for multiple comparisons. …”
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Características clínicas, epidemiológicas y terapéuticas de pacientes atendidos en la unidad de cuidados intensivos by Julio César González Aguilera, Víctor Manuel Leyva Lorenzo, Yoleinis Esperanza Vázquez Belizón, Armando Arias Ortiz, Jorge Omar Cabrera Lavernia

“…Al 27,3 % se le implantó catéter venoso central y el 13,9 % recibió ventilación mecánica artificial. …”
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The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

“…Animals in the experimental group were injected with a solution of triptorelin at a dose of 0.3 mg of active substance per 1 kg of animal weight to modulate central deprivation of luteinising hormone synthesis. …”
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Improving Individualized Salbutamol Treatment: A Population Pharmacokinetic Model for Oral Salbutamol in Virtual Patients by Lara Marques, Nuno Vale

“…Relationships were identified between gender and mean transit time (M_tt) and clearance (C<i>l</i>), as well as the effects of weight and BSA on the volume of distribution of the central compartment (V1) and C<i>l</i>, and a significant impact of health status on C<i>l</i>. …”
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Equine piroplasmosis in different geographical areas in France: Prevalence heterogeneity of asymptomatic carriers and low genetic diversity of Theileria equi and Babesia caballi by Maggy Jouglin, Claire Bonsergent, Nathalie de la Cotte, Mickaël Mège, Céline Bizon, Anne Couroucé, Élodie-Anne Lallemand, Agnès Leblond, Louise C Lemonnier, Aurélia Leroux, Ilaria Marano, Alexandre Muzard, Émilie Quéré, Marion Toussaint, Albert Agoulon, Laurence Malandrin

“…We developed a species-specific nested PCR protocol targeting the 18S small sub-unit (SSU) rRNA gene and used it on blood samples collected from 566 asymptomatic horses across four National Veterinary Schools.The carrier frequency varied from 18.7 % around Paris (central-north) to 56.1 % around Lyon (southeast), with an overall prevalence of 38.3 %. …”
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Spatiotemporal clustering of anthrax and molecular typing of Bacillus anthracis in Ningxia Hui Autonomous Region, 2019 – 2022 by Ran XIAN, Cong YANG, Jianwei GAO, Lei GAO, Qian CHEN, Yu ZHAO, Wenhe KUAI, Haohao FAN, Xiaodi LI, Jiangtao MA

“…SaTScan spatiotemporal cluster analysis revealed a spatiotemporal cluster in north-central Ningxia from 2021 to 2022, with a primary cluster in Yongning county [P < 0.01, relative risk (RR) = 13.83] and secondary clusters in Lingwu city and Litong district (P = 0.022, RR = 3.47). …”
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Geometrical Features of Subbasal Corneal Whorl-like Nerve Patterns in Dry Eye Disease by Ziqing Feng, MD, Kang Yu, MD, Yupei Chen, MS, Gengyuan Wang, MS, Yuqing Deng, MD, Wei Wang, MD, Ruiwen Xu, MD, Yimin Zhang, MD, Peng Xiao, PhD, Jin Yuan, MD, PhD

“…Methods: All subjects underwent comprehensive ophthalmic examinations, dry eye tests, and in vivo confocal microscopy to visualize the whorl-like corneal nerve at the inferior whorl (IW) region and the straight nerve at the central cornea. The structure of the corneal nerve was extracted and characterized using the fractal dimension (CNDf), multifractal dimension (CND0), tortuosity (CNTor), fiber length (CNFL), and numbers of branching points. …”
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Influence of Type 1 Diabetes Mellitus on the Ocular Biometry of Chinese Children by Ying Xiao, Tao Li, Yan Jia, Shanshan Wang, Chenhao Yang, Haidong Zou

“…The participants were evaluated for central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), K1 and K2 keratometry, and axial length (AL); also cycloplegic refraction was performed, and spherical equivalent (SE) was acquired. …”
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Optimizing Coastal Management: A Comprehensive Value Chain Analysis Approach for Sustainable Economic Development in Java, Indonesia by Zuhud Rozaki, Ahmad Shabudin Ariffin, Mona Fairuz Ramli, Elvina Nurrohma, Novara Nurvinka Ramadhani, Winda Ismah Setyoasih, Masateru Senge

“…For the northern coast, milkfish and ariid catfish from Juwana Coast (Pati Regency, Central Java) were selected, while Whiteleg Shrimp from Mendit Coast and Trisik Coast of Kulon Progo Regency, Yogyakarta were chosen to represent the southern coast. …”
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