Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats by Michael J. Butler, Stephanie M. Muscat, Maria Elisa Caetano-Silva, Akriti Shrestha, Brigitte M. González Olmo, Sabrina E. Mackey-Alfonso, Nashali Massa, Bryan D. Alvarez, Jade A. Blackwell, Menaz N. Bettes, James W. DeMarsh, Robert H. McCusker, Jacob M. Allen, Ruth M. Barrientos

“…Thus, our study investigated the impact of HFD after two distinct consumption durations: 3 months (to model diet-induced obesity) or 3 days (to detect the rapid changes occurring with HFD) on memory function, anxiety-like behavior, central and peripheral inflammation, and gut microbiome profile in young and aged rats. …”
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SOCIAL AND ECONOMIC DEVELOPMENT OF MAGADAN: FROM A PLANNED ECONOMY TO A MARKET ECONOMY (1960–2020) by Natalya V. Galtseva, Oksana S. Favstritskaya, Olga A. Sharypova

“…Although northern cities are relatively younger than their central and southern counterparts, they serve as strategic hubs for the development of critical territories, including the Arctic. …”

The Impact of Digital Challenges On the Development of Startups In the Tourism Sector In Algeria by Narimane Benabderrahmane

“…Most tourism startups are located in the North-Central region due to the region's favorable ecosystem. …”
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Projected range overlap between the predator Teretrius nigrescens and the invasive stored product pest Prostephanus truncatus expands under climate change by Rachel R. Harman, William R. Morrison, III, Alison R. Gerken

“…The larger grain borer, Prostephanus truncatus (Horn) (Coleoptera: Bostrichidae), is a forest-dwelling destructive pest of stored corn and cassava native to Central America and invasive in Africa. Its native predator, Teretrius nigrescens Lewis (Coleoptera: Histeridae), was released in Africa as a biocontrol agent with some success. …”
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Is it feasible to treat polycystic ovarian syndrome with or without insulin resistance using glucokinase activators as novel hypoglycaemic medications? A protocol for a systematic... by Xiaojing Liu, Lei Zeng, Shuo Yuan, Genping Zeng, Xijing Lu, Peiyin Li, Tan Zeng, Zitong Lin, Yuxi Miao

“…The meta-analysis protocol aims to address this knowledge gap, furnish evidence-based data to support potential revisions in PCOS treatment guidelines and promote the utilisation of GKAs in clinical settings.Methods and analysis A comprehensive search will be conducted across the Cochrane Central Register of Controlled Trials, PubMed, Web of Science, Embase, Medline, Scopus, CNKI, Wanfang and VIP databases to identify randomised controlled trials investigating the use of GKAs in the treatment of PCOS, irrespective of the presence of IR. …”
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How pragmatic are randomised controlled trials evaluating minimally invasive surgery for oesophageal cancer? A methodological review of trial design using the Pragmatic-Explanatory... by Natalie S Blencowe, Jane Blazeby, Sian Cousins, Katy Chalmers

“…Abstracts, pilot and feasibility studies, and systematic reviews were excluded.Sources of evidence Three sequential searches of Ovid MEDLINE, Embase and CENTRAL electronic databases and clinical trials registry databases.Charting methods Two independent reviewers screened the articles and used appropriate, validated tools (Pragmatic-Explanatory Continuum Indicator Summary-2 (PRECIS-2) and Risk of Bias 2) to assess study quality. …”
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Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

“…Abstract Deposition of abnormally phosphorylated tau aggregates is a central event leading to neuronal dysfunction and death in Alzheimer’s disease (AD) and other tauopathies. …”
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Antibacterial and Antioxidant Activities of Triterpenoids and Cyclic 1,7-Diarylheptanoids from the Stem Bark of Myrica salicifolia: A Combined Experimental and Computational Study by Abraham Dilnesa Gashaw, Kibrom Gebreheiwot Bedane, Taye B. Demissie, Japheth O. Ombito, Estifanos Ele Yaya, Mekonnen Abebayehu Desta

“…Myricasalicifolia A Rich (Myricaceae) is a tree growing in Central and East Africa. Traditionally, the plant is used to treat malaria, respiratory disorders, inflammations, and infections. …”
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Acute kidney injury is associated with liver-related outcomes in patients with hepatitis B virus infection: a retrospective cohort study by Jiao Liu, Ruixuan Chen, Shiyu Zhou, Zhixin Guo, Licong Su, Lisha Cao, Yanqin Li, Xiaodong Zhang, Fan Luo, Ruqi Xu, Qi Gao, Yuxin Lin, Xin Xu, Sheng Nie, the CRDS study Investigators

“…Methods The multicenter, retrospective cohort study included Chinese adults with HBV infection from 24 regional central hospitals between January 2000 and December 2022. …”
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Improving WRF-Chem PM2.5 predictions by combining data assimilation and deep-learning-based bias correction by Xingxing Ma, Hongnian Liu, Zhen Peng

“…Besides having the best optimization effect over the whole domain, the combined method also performed well in different regions: during the forecasting period of 0–24 h, the RMSEs decreased from 32 % to 62 %, 39 % to 57 %, 28 % to 40 %, and 30 % to 49 % in the Beijing–Tianjin–Hebei, Yangtze River Delta, Central China, and Sichuan Basin urban agglomerations, respectively.…”
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Comparative Proteomic Analysis of Visceral Adipose Tissue in Morbidly Obese and Normal Weight Chinese Women by Chen Shang, Wei Sun, Chunlin Wang, Xiangqing Wang, Huijuan Zhu, Linjie Wang, Hongbo Yang, Xue Wang, Fengying Gong, Hui Pan

“…Visceral adipose tissue (VAT) plays a central role in the balance of energy metabolism. …”
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Frente invertido: un análisis comparado Brasil-México de la gestión económica y sanitaria de la covid-19 by Mireille Razafindrakoto, François Roubaud, Pierre Salama, Alexis Saludjian

“…Tras establecer un diagnóstico preciso de las políticas aplicadas para hacer frente a la crisis, así como de la situación económica y sanitaria de los dos países durante 2020-2022, proponemos una interpretación original del papel central desempeñado por los dos presidentes.…”
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Assessing the inflammation in pediatric MOGAD: Significance of CSF HMGB1 and related biomarkers by Xin Wang, Ruibin Zhao, Jiayu Fan, Chong Liu, Li Zhang, Huafang Yang, Weiyi Wang

“…Background and purposeMyelin-oligodendrocyte glycoprotein antibody associated disease (MOGAD) is a common inflammatory disease of the central nervous system (CNS) in children that can lead to demyelination. …”
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Clinical application of 3D slicer reconstruction and 3D printing localization combined with neuroendoscopy technology in VPS surgery by Long Zhou, Pan Lei, Ping Song, Zhiyang Li, Huikai Zhang, Hangyu Wei, Lun Gao, Qiuwei Hua, Hui Ye, Qianxue Chen, Silei Zhang, Qiang Cai

“…According to the unique ventricular system characteristics of each hydrocephalus patient, the 3D Slicer reconstruction technology was used to determine the individualized puncture point and direction, measure the puncture depth, accurately locate the puncture through the 3D printing guide plate, and accurately send the tip of the ventricular catheter into the frontal or central part of the lateral ventricle with the assistance of neuroendoscopic visualization, which improved the success rate of the operation and reduced the risk of tube blockage. …”
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Isolation, Identification, and Pathogenicity of Potential Probiotics Isolated from Intestinal Coconut Crab (Birgus latro Linnaeus, 1767) by Muhammad Aris, Tamrin Tamrin, Waode Munaeni, Sudirto Malan, Juharni Juharni, Rusmawati Labenua

“…Coconut crab samples were collected from Moor Island, South Patani District, Central Halmahera Regency, North Maluku Province, Indonesia. …”
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“you just look at rocks, and have beards” Perceptions of Geology From the United Kingdom: A Qualitative Analysis From an Online Survey by Steven L. Rogers, Sam Giles, Natasha Dowey, Sarah E. Greene, Rehemat Bhatia, Katrien Van Landeghem, Chris King

“…Finding new ways to show that, far from being boring, geology is a subject that can fundamentally change the way you see and interact with the world around you is of central importance to achieving this. Efforts to make the subject more equitable are also highlighted as being critical in creating a more inclusive and accessible discipline.…”
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Phenolic-Rich Baccaurea angulata Modulates Inflammatory Biomarkers of Atherosclerosis by Muhammad Ibrahim, Maryam Abimbola Mikail, Idris Adewale Ahmed, Radiah Abdul Ghani

“…Inflammation has been progressively acknowledged as a vital and central player in the pathophysiology of atherosclerosis. …”
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Study on the Impact of Climate Warming on Mariculture in China by GAO Jia, YANG Huaiyu

“…The results show that: (1) Although there are inter-annual fluctuations and regional differencesin temperature changes among provinces (autonomous regions and municipalities directly under the Central Government) there is an upward trend on the whole, confirming the macro background of global warming. (2) The overall output of mariculture in China is generally on the rise, especially in Liaoning, Shandong, Fujian, Guangdong and other provinces, which have become the core regions of mariculture in China. (3) Through in-depth analysis of the correlation between the temperature and the mariculture yield, it is found that there is a significant negative relationship between the two, that is, every 1% increase in temperature will lead to a decrease of about 2.65% in the mariculture yield. …”
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Evaluation of positions of four lingula shapes for mandibular ramus surgery by Kun-Jung Hsu, Kun-Jung Hsu, Pei-Jung Chen, Han-Sheng Chen, Han-Sheng Chen, Kun-Tsung Lee, Kun-Tsung Lee, Chun-Ming Chen, Chun-Ming Chen

“…There were no significant differences in measurements between male and female.ConclusionSignificant differences were observed in the 4 lingula shapes in relation to the Li position, which was situated superiorly and posteriorly to the central point of the ramus. Therefore, it is crucial to take into account the differences in lingula shapes during SSRO and IVRO procedures on the ramus.…”
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Association of cortical macrostructural and microstructural changes with cognitive performance and gene expression in subcortical ischemic vascular disease patients with cognitive... by Jing Huang, Runtian Cheng, Xiaoshuang Liu, Li Chen, Tianyou Luo

“…The significantly reduced cortical thicknesses of the right insula, left superior temporal gyrus, left central anterior gyrus, and left caudal anterior cingulate cortex, as well as the significantly reduced cortical LGI in left caudal anterior cingulate cortex, were significantly positively correlated with different cognitive scores (P < 0.05). …”
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