Efficacy of brief intervention for drug misuse in primary care facilities: systematic review and meta-analysis protocol by Toshi A Furukawa, Yan Luo, Norio Watanabe, Ethan Sahker, Masatsugu Sakata, Rie Toyomoto, Chiyoung Hwang, Kazufumi Yoshida

“…We will retrieve all studies through searches in CENTRAL, Embase, MEDLINE and PsycINFO until 31 May 2020. …”
Get full text

Optimized Removal of Hydroquinone and Resorcinol by Activated Carbon Based on Shea Residue (Vitellaria paradoxa): Thermodynamics, Adsorption Mechanism, Nonlinear Kinetics, and Isot... by Liouna Adoum Amola, Theophile Kamgaing, Rufis Fregue Tiegam Tagne, Cyrille Donlifack Atemkeng, Idris-Hermann Tiotsop Kuete, Solomon Gabche Anagho

“…The adsorbent was prepared chemically by impregnation with sulfuric acid and coded by the acronym CAK-S. The central composite design (CCD) was used to optimize the main factors that influence the adsorption of HQ or R by activated carbon such as the initial concentration, the pH of the solution, the contact time, and the mass of the carbon on the expected response, which is the adsorbed quantity of the target pollutants. …”
Get full text

Clinical Significance of Perioperative Minimal Residual Disease Detected by Circulating Tumor DNA in Patients With Lung Cancer With a Long Follow-up Data: An Exploratory Study by Shuta Ohara, MD, PhD, Kenichi Suda, MD, PhD, Sumedha Sudhaman, PhD, Akira Hamada, MD, PhD, Masato Chiba, MD, PhD, Masaki Shimoji, MD, PhD, Toshiki Takemoto, MD, PhD, Ekaterina Kalashnikova, PhD, Samantha K. Cheung, PhD, Michael Krainock, MD, PhD, Jordan Feeney, BS, Himanshu Sethi, MPH, Minetta C. Liu, MD, Junichi Soh, MD, PhD, Yasuhiro Tsutani, MD, PhD, Tetsuya Mitsudomi, MD, PhD

“…Three patients who had central nervous system–only metastases did not have detectable ctDNA. …”
Get full text

Quantitative risk assessment of rainstorm-induced flood disaster in Piedmont plain of Pakistan by Ming Chang, Kangchi Zhou, Xiangyang Dou, Fenghuan Su, Bo Yu

“…Abstract Pakistan’s geographic location makes it an important land hub between Central Asia, Middle East-North Africa, and China. …”
Get full text

Novel Poly-Arginine Peptide R18D Reduces α-Synuclein Aggregation and Uptake of α-Synuclein Seeds in Cortical Neurons by Emma C. Robinson, Anastazja M. Gorecki, Samuel R. Pesce, Vaishali Bagda, Ryan S. Anderton, Bruno P. Meloni

“…Background/Objectives: The role of α-synuclein (α-syn) pathology in Parkinson’s disease (PD) is well established; however, effective therapies remain elusive. Two mechanisms central to PD neurodegeneration are the intracellular aggregation of misfolded α-syn and the uptake of α-syn aggregates into neurons. …”
Get full text

Benefits and Risks of Clopidogrel vs. Aspirin Monotherapy after Recent Ischemic Stroke: A Systematic Review and Meta-Analysis by Maurizio Paciaroni, Birsen Ince, Bo Hu, Jiann-Shing Jeng, Kursad Kutluk, Liping Liu, Min Lou, Vladimir Parfenov, Ka Sing Lawrence Wong, Babak Zamani, Dara Paek, Jung Min Han, Michael del Aguila, Shalini Girotra

“…Methods. PubMed, Embase, and CENTRAL databases were searched from inception to May 2018 to identify clinical trials and observational studies comparing clopidogrel versus aspirin for secondary prevention in patients with recent ischemic stroke within 12 months. …”
Get full text

Tasks scheduling with different structures in cloud manufacturing according to the time and cost of transportation and the task arrival time by Zohre Kiapasha, Ali Salmasnia

“…Purpose: Cloud manufacturing is a service-oriented production model that centralizes production resources to respond to specific customer needs in different locations. …”
Get full text

A Case of Carbamazepine-Induced Aggravation of Self-Limited Epilepsy with Centrotemporal Spikes Epilepsy and Valproate-Induced Hyperammonemic Encephalopathy in a Child with Heteroz... by Imalke Kankananarachchi, Eresha Jasinge, Gemunu Hewawitharana

“…His electroencephalogram (EEG) showed bilateral predominantly on the right-sided central-temporal spikes and waves. The diagnosis of SLECTS was made, and he was commenced on CBZ. …”
Get full text

Experimental Study of Single Expansion Ramp Nozzle Performance Using Pitot Pressure and Static Pressure Measurements by Sergio Nicolas Pachón Laitón, João Felipe de Araujo Martos, Israel da Silveira Rego, George Santos Marinho, Paulo Gilberto de Paula Toro

“…Static pressure measurements at the centerline of the nozzle show that the residence time of the flow in the expansion section is short enough and the flow of the central region of the nozzle is not altered by the lateral expansion when nozzle configuration does not include side walls.…”
Get full text

Clinical impact of [18F]FDG-PET/CT in ARI0002h treatment, a CAR-T against BCMA for relapsed/refractory multiple myeloma by Inés Zugasti, Marta Tormo-Ratera, Aina Oliver-Caldés, Juan Carlos Soler-Perromat, Verónica González-Calle, David F. Moreno, Valentín Cabañas, Nieves López-Muñoz, Álvaro Bartolomé-Solanas, Marta Español-Rego, Juan Luis Reguera-Ortega, Laura Rosiñol, Lucía López-Corral, Natalia Tovar, Luis Gerardo Rodríguez-Lobato, Rosa Maria Alvarez Perez, Sara Varea, Eulàlia Olesti, Adolfo Gomez-Grande, Laura Frutos, Pilar Tamayo, Manel Juan, José M. Moraleda, Álvaro Urbano-Ispizua, E. Azucena González-Navarro, Joaquín Martínez-López, Maria-Victoria Mateos, Xavier Tomás, Xavier Setoain, Carlos Fernández de Larrea

“…Baseline [18F]fluorodeoxyglucose (FDG)–positron emission tomography (PET)/computed tomography (CT) from 5 participating centers were reviewed centrally. Of 63 patients, 52.4% presented plasmacytomas at the time of inclusion (21 PS, exclusively; and 12 EMD). …”
Get full text

Recent advances in the application of Mendelian randomization to chronic kidney disease by Chaofan Wen, Lanlan Chen, Dan Jia, Ziqi Liu, Yidan Lin, Guan Liu, Shuo Zhang, Baoshan Gao

“…New insights also reveal a substantial causal connection between both central and general obesity and CKD onset, while no significant links were found between genetically modified LDL cholesterol or triglyceride levels and kidney function.Conclusion This review not only presents the recent achievements of MR in CKD research but also illuminates the path forwards, underscoring critical unanswered questions and proposing future research directions in this dynamic field.…”
Get full text

Carreira profissional de homens e mulheres no setor de turismo: intersecção de profissão, carreira e divisão sexual do trabalho by Thiago Eduardo Freitas Bicalho, Eloiza Helena Gonçalves Maia, Raquel Quirino

“… A atividade turística se desenvolve como uma das principais empregadoras do setor de serviços, contudo, há diferença entre ser profissional homem e ser profissional mulher e, consequentemente, este fator influencia as carreiras profissionais no setor de turismo. A questão central desta pesquisa é responder em que medida as produções científicas - teses e dissertações - abordam a intersecção da carreira profissional de homens e mulheres com o trabalho no setor de turismo. …”
Get full text

Incremental long-term benefit of drug therapies for chronic obstructive pulmonary disease in quality of life but not mortality: a network meta-analysis by Qiong Pan, Jiongzhou Sun, Shiyuan Gao, Zian Liu, Yiwen Huang, Yixin Lian

“…Material and methods This study retrieved randomised clinical trials (RCTs) with follow-up ≥ 48 weeks on long-acting β-agonists (LABAs), long-acting muscarinic receptor antagonists (LAMAs), inhaled corticosteroids (ICSs), and dupilumab in the PubMed, EMBASE, and Cochrane Central Register of Controlled Trials databases. The information on eligible studies was extracted after the screening. …”
Get full text

Recent Advances in the Mechanisms of Postoperative Neurocognitive Dysfunction: A Narrative Review by Tingting Wang, Xin Huang, Shujun Sun, Yafeng Wang, Linlin Han, Tao Zhang, Tianhao Zhang, Xiangdong Chen

“…Key findings highlight neuroinflammation, oxidative stress, mitochondrial dysfunction, neurotransmitter imbalances, microvascular changes, and white matter lesions as central to PND pathophysiology, with particular parallels to encephalocele- and sepsis-associated cognitive impairments. …”
Get full text

Autoinflammatory diseases. Part 1: concept, classification, immunobiology, diagnosis by O.V. Shvaratska, M.V. Kalichevska, O.V. Klymenko, O.M. Taran, O.V. Klimova, Y.V. Vilenskyi, T.M. Plekhanova, T.K. Mavropulo

“…We performed a focused search over the Web of Science, Scopus, PubMed Central®, Google Scholar databases over the past 10 years using the keywords “autoinflammatory diseases”, “autoinflammatory syndromes”, “autoinflammation”. …”
Get full text

VALIDAÇÃO DE EQUAÇÕES ANTROPOMÉTRICAS PARA A ESTIMATIVA DA DENSIDADE CORPORAL EM HOMENS by Edio Luiz Petroski, Cândido Simões Pires Neto

“…Foram envolvidos no estudo 304 homens das regiões central do RS e litorânea de SC, com média de idade de 30,17 ± 9,78 anos. …”
Get full text

Massive Spontaneous Hemothorax as a Complication of Apixaban Treatment by M. Abu Hishmeh, P. Srivastava, Q. Lougheide, M. Srinivasan, S. Murthy

“…Hemothorax is usually related to chest or iatrogenic trauma from procedures such as central lines and thoracentesis. Spontaneous hemothorax is defined as pleural fluid hematocrit greater than 50% of serum hematocrit in absence of natural or iatrogenic trauma affecting the lung or pleural space. …”
Get full text

Outcomes and predictive factors for fluid resolution following three loading injections of faricimab for treatment-naïve neovascular age-related macular degeneration by Hee Yong Han, Sang Min Park, Ji Hyun Lee, Chul Gu Kim, Jong Woo Kim, Han Joo Cho, Jae Hui Kim

“…Changes in best-corrected visual acuity(BCVA) and central retinal thickness(CRT) following treatment were evaluated. …”
Get full text

Turkic-Speaking Population on the Steppe Borderland of the Grand Duchy of Lithuania and the Crimean Khanate in the 15th – the First Half of the 16th Centuries by Vladyslav V. Hrybovskyi

“… The ethnic and demographic situation on the borderland of the Grand Duchy of Lithuania and the Crimean Khanates is analysed on the basis of narratives (Michalon Lituanus, Marcin Broniowski, Marcin Bielski, Bartosz Paprocki) and documentary sources (publications “Lithuanian Metrics”, “Archive of South Western Russia”, documents of the Russian State Archive of Ancient Acts, Central State Historical Archive of Ukraine). The boundaries laid by the local prince of Kiev Simeon Olelkovich in the 15th century were significant for a later time as a precedent for ideas about the boundary between the Black Sea Tatars and Ukrainian Cossacks. …”
Get full text

The Role of Technical Car Features in Managing and Promoting New Peer-to-Peer Car-Sharing Systems: Insights from Potential Users and Strategic Implications for Service Providers by Katarzyna Turoń, Andrzej Kubik, Piotr Folęga, Andrzej Wilk, Peter Bindzar, Truong M. N. Bui

“…The network structure, characterized by a relatively low density (0.2536) and a short average path length (1.872), suggests that a few central vehicle features dominate user decisions, and improvements in these key areas can quickly propagate through the decision-making process, enhancing overall user satisfaction. …”
Get full text