Is epinephrine still the drug of choice during cardiac arrest in the emergency department of the hospital? A meta-analysis by Hou Min, Dong Su, Kan Qing, Ouyang Meng, Zhang Yun

“…Pertinent articles were searched in central databases like PubMed, Scopus, and Web of Science, using appropriate keywords as per the PRISMA guidelines. …”
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Comparative efficacy and safety of 20 intravenous pharmaceutical intervention for prevention of etomidate-induced myoclonus: a systematic review and Bayesian network meta-analysis by Lu Chen, Lu Chen, Pengxiang Zhou, Pengxiang Zhou, Zhengqian Li, Ziyang Wu, Suodi Zhai, Suodi Zhai

“…ObjectiveTo compare the efficacy and safety of pharmaceutical interventions to prevent etomidate-induced myoclonus (EIM), providing the optimal intervention for clinical practice.MethodsPubMed, Embase, the Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, Chinese National Knowledge Infrastructure, WanFang database, and SinoMed database were searched from the inception to sixth May 2024. …”
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Analysis of the use of digital technologies at enterprises of the shipbuilding industry of the military-industrial complex by Lipatnikov Vitalii, Smirnova Ol'ga, Lebedkin Pavel

“…The introduction of digital technologies in warehouses and supply chain management allows one to monitor balances in real time and purchase the necessary materials without the direct presence of a person. The need for centralized state support for the digitalization of control systems in the MIC is also separately noted.…”
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The p85 Regulatory Subunit of PI3K Mediates cAMP-PKA and Insulin Biological Effects on MCF-7 Cell Growth and Motility by E. Di Zazzo, A. Feola, C. Zuchegna, A. Romano, C. F. Donini, S. Bartollino, C. Costagliola, R. Frunzio, P. Laccetti, M. Di Domenico, A. Porcellini

“…Furthermore, the p85αPI3KS83 phosphorylation plays a central role in the control of insulin-mediated cell proliferation, cell migration, and adhesion. …”
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Induced Defense in Ryegrass–Epichloë Symbiosis Against <i>Listronotus bonariensis</i>: Impact on Peramine Levels and Pest Performance by Manuel Chacón-Fuentes, Gunnary León-Finalé, Marcelo Lizama, Gastón Gutiérrez-Gamboa, Daniel Martínez-Cisterna, Andrés Quiroz, Leonardo Bardehle

“…In addition, ryegrass can activate induced defense mechanisms, with peramine remaining the central agent in response to herbivorous insect attacks. …”
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Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus by Han-Fang Wu, Yi-Ju Chen, Su-Zhen Wu, Chi-Wei Lee, I-Tuan Chen, Yi-Chao Lee, Chi-Chen Huang, Chung-Hsi Hsing, Chih-Wei Tang, Hui-Ching Lin

“…The role of EETs in synaptic function in the central nervous system is still largely unknown. We found that pharmacological inhibition of sEH to stabilize endogenous EETs and exogenous 14,15-EET significantly increased the field excitatory postsynaptic potential (fEPSP) response in the CA1 area of the hippocampus, while additionally enhancing high-frequency stimulation- (HFS-) induced long-term potentiation (LTP) and forskolin- (FSK-) induced LTP. sEH inhibitor (sEHI) N-[1-(oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy) phenyl)-urea (TPPU) and exogenous 14,15-EET increased HFS-LTP, which could be blocked by an N-methyl-D-aspartate (NMDA) receptor subunit NR2B antagonist. …”
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K-núcleo: Una herramienta para detectar la estructura conceptual de los campos de investigación. El caso práctico de las Altmetrías by Carmen Gálvez

“…El resultado fue la detección de cinco capas diferenciadas. Una capa central con conceptos básicos y densamente interconectados, que formaron la base de conocimiento del campo. …”
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ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway by Xi Zhu, Xiaogang Zhang, Xinpeng Cong, Luoning Zhu, Zhongping Ning

“…Atrial fibrillation (AF) is the more significant portion of arrhythmia in clinical practice, with inflammation and fibrosis as its central pathological mechanisms. This study aimed to investigate angiopoietin-like 4 (ANGPTL4) effects on angiotensin II- (Ang II-) induced AF and its related pathophysiological mechanisms. …”
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Developing a core outcome set for interventions in people with mild cognitive impairment: study protocol by Angus G K McNair, Nicholas Turner, Alan Richardson, Elizabeth Coulthard, Jemima Dooley, Julie Clayton, Sam Harding, Sarah Rudd, Victoria Grace Gabb, Winsome Barrett-Muir, Natalie Woodward, Sophie Alderman, Joseph Webb

“…Patient and public involvement and engagement are central to developing the COS. The results will be disseminated via conferences, peer-reviewed publications, briefing notes to key agencies, to the public via social media and blog posts and directly to stakeholders who participate in the project.Trial registration number Core Outcome Measures in Effectiveness Trials Initiative 2117; PROSPERO registration: CRD42023452514.…”
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Medialization of shaft of humerus to provide medial buttress and prevent varus collapse in 3- and 4-part proximal humerus fractures: review of the surgical technique by Srinivas Kasha, MS(Ortho), Ranjith Kumar Yalamanchili, MS(Ortho), G.P.R.K. Rohit, MS(Ortho), Suresh Krishna Lokayah, MS(Ortho), Varun Kulkarni, MBBS

“…Methods: This retrospective study included acute 3-part and 4-part proximal humerus fractures treated with open reduction and proximal humerus locking plate fixation from February 2013 to August 2021, which were restored by creating medial buttress by the described technique. Central Column Diaphyseal angle was measured on the 20° external rotation anteroposterior X-ray radiograph, by measuring the intersection angle of the axis of the proximal part of the humerus and the line perpendicular to the anatomical neck. …”
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Resilience to climate-induced food insecurity in Nigeria: a systematic review of the role of adaptation strategies in flood and drought mitigation by Timothy A. Akinkuolie, Timothy A. Akinkuolie, Timothy O. Ogunbode, Aruna O. Adekiya

“…This review explores the effects of climate change-induced droughts and floods on food security in Nigeria, where agriculture is central to economic stability and livelihoods.MethodsThe analysis integrates a comprehensive metadata evaluation, identifying trends, thematic gaps, and regional disparities in existing research. …”
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BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice by Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher, Martin Gengenbacher

“…Concurrently, we observed an increased frequency of central memory T cells, a subset critical for protective immunity. …”
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The Impact of Onchocerciasis Elimination Measures in Africa: A Systematic Review by Policarpo Ncogo, Christine Giesen, María Jesús Perteguer, Maria P. Rebollo, Rufino Nguema, Agustín Benito, Zaida Herrador

“…All scientific articles indexed in the PubMed, Scopus, Embase, and CENTRAL databases written in Spanish, English, French, German, and Portuguese were considered. …”
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Ovaries of Lumbricidae earthworms (Annelida, Crassiclitellata), from morphology to ultrastructure by D. Raś, C. Csuzdi, A. Z. Urbisz, Ł. Gajda, K. Małota, P. Świątek

“…Clustering cells are interconnected via intercellular bridges to the poorly developed central cytoplasmic mass (reticular cytophore). According to the histological and ultrastructural results, ovaries can be divided into three zones. …”
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Application of response surface methodology in optimizing MOF5@Fe3O4 catalyst for activating peroxymonosulfate in the degradation of reactive black 5 dye by Nezamaddin Mengelizadeh, Najmeh Ahmadi, Davoud Balarak

“…Modeling and optimization of operational parameters were performed using response surface methodology coupled with central composite design (RSM-CCD). The maximum removal efficiency of RB5 was predicted under laboratory conditions, including pH of 11, catalyst dosage of 1 g/L, RB5 concentration of 10 mg/L, temperature of 50 °C, and reaction time of 60 min. …”
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The clinical impact of conventional therapies for adults and adolescents suffering from eosinophilic esophagitis, a type 2 inflammatory chronic disease, and their economic conseque... by Giorgio Walter Canonica, MD, Gherardo Mazziotti, MD, PhD, Alessandro Repici, MD, Massimiliano Povero, PhD, Luca Castello, MSc, Lorenzo Pradelli, MD, Miryana Dobreva, MSc, Francesca Fanelli, MSc, Jean Pierre Saab, MD, Edoardo Vincenzo Savarino, MD, PhD

“…Methods: MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched up to December 2023 and 78 publications were included, covering treatment outcomes and adverse events. …”
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EFFECTIVENESS OF GOALBALL ATHLETES THROWING IN THE CHILEAN NATIONAL LEAGUE by M.Sc. Kevin Isaías Campos Campos, Ph.D Luis Felipe Castelli Correia de Campos, Ph.D Marcio Pereira Morato, M.Sc. Alessandro Tosim, M.Sc. Mónica Fernández Muñoz, M.Sc.. Karina Alarcón Segura, Ph.D Cristian Luarte Rocha

“…The lateral positions execute throws, preferably FRO, but in defense the central positions are protagonists. Throws are most effective when they are directed in PA and SD.…”
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Psychological interventions for chronic non-specific low back pain: protocol of a systematic review with network meta-analysis by Lingxiao Chen, Jill Hayden, Manuela Ferreira, Emma Ho, Milena Simic, Claire Ashton-James, Josielli Comachio, Paulo Ferreira

“…Therefore, we will perform a systematic review with a NMA to determine which type of psychological intervention is most effective for adults with chronic non-specific LBP.Methods and analysis We will search electronic databases (MEDLINE, Embase, PsycINFO, Cochrane Central Register of Controlled Trials, Web of Science, SCOPUS and CINAHL) from inception until 22 August 2019 for randomised controlled trials comparing psychological interventions to any comparison interventions in adults with chronic non-specific LBP. …”
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Incidence and Factors Associated with Postoperative Delayed Hyponatremia after Transsphenoidal Pituitary Surgery: A Meta-Analysis and Systematic Review by Cheng-Chi Lee, Yu-Chi Wang, Yu-Tse Liu, Yin-Cheng Huang, Peng-Wei Hsu, Kuo-Chen Wei, Ko-Ting Chen, Ya-Jui Lin, Chi-Cheng Chuang

“…Methods. PubMed, EMBASE, and CENTRAL databases were searched until September 1, 2020. …”
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Comparison of the strength of resistance spot-welded, bonded, and hybrid single lap joints: A numerical investigation by Murat Demiral, Ali Mamedov

“…While traditional methods such as bolting, riveting, and resistance spot welding have been central to structural assembly, they face limitations under modern engineering demands like higher strength, weight reduction, improved fatigue life and damage tolerance. …”
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