Acupuncture treatment of restless legs syndrome: a randomized clinical controlled study protocol based on PET-CT and fMRI by Lin Tang, Na Zhao, Xiaolin Gao, Jinjin Li, Xintong Yu, Ruilong Liang, Chen Xie, Lutong Li, Qianqian Wang, Wenjia Yang

“…This randomized controlled trial (RCT) aims to investigate the efficacy of acupuncture in the treatment of RLS and further explore the central response mechanism of acupuncture in the treatment of RLS.Methods and analysisIn this RCT, a total of 124 eligible patients in Shanghai will be randomly assigned to one of the following two groups: treatment group (acupuncture) and control group (sham acupuncture). …”
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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging by Hugo Helbert, Winnie Deuther-Conrad, Michel de Haan, Barbara Wenzel, Gert Luurtsema, Wiktor Szymanski, Peter Brust, Rudi A. J. O. Dierckx, Ben L. Feringa, Philip H. Elsinga

“…Abstract Background Through its central role in neurotransmission, the vesicular acetylcholine transporter (VAChT) is an increasingly valuable target for positron emission tomography (PET). …”
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A solution at the doorsteps: Improved biofertilizer enhances soil fertility and yield of Chili ( Capsicum an-nuumL.) in Bhutan by Sonam Tashi, Kesang Wangchuk, Erica Udas, Sonam Gaki, Kamal Aryal

“…Purpose Two field experiments were conducted to evaluate the effects of locally prepared biofertilizers (Jholmal 1 and Jholmal 2) on soil properties and chili yield (Capsicum annuum L.).Method The experimental site was in west-central Bhutan. The experiments were Randomized Complete Block Designs (RCBD) consisting of three treatments (cattle dung/ urine: Jholmal 1, cattle urine: Jholmal 2, and Control), and each treatment was replicated four times. …”
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Crotalus durissus ruruima Snake Venom and a Phospholipase A2 Isolated from This Venom Elicit Macrophages to Form Lipid Droplets and Synthesize Inflammatory Lipid Mediators by Ana Eduarda Zulim de Carvalho, Karina Giannotti, Elbio Leiguez Junior, Márcio Matsubara, Maria Cristina Dos Santos, Consuelo Latorre Fortes-Dias, Catarina Teixeira

“…Macrophages are cells with a central role in inflammatory and immunological responses. …”
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Entrepreneurship in Medical Education: Evaluation of the Entrepreneurship in Healthcare Seminar Series by Amanda Mac, Hayley McKee, Michael Balas, Aazad Abbas, Aida Ahrari, Pawandeep Sandhu, Dante Morra, Sarah McClennan, Alison Freeland

“… Background: Innovation and entrepreneurship are central to healthcare. Physicians are ideally positioned to create sustainable healthcare innovations. …”
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HIV and AIDS prevention behavior among housewives in South Purwokerto sub-district, Indonesia by Colti Sistiarani, Dian Anandari, Elviera Gamelia

“…South Purwokerto is a sub-district in Banyumas District, Central Java, Indonesia, with sexually transmitted infection (STI) cases as many as 45 people. …”
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PFAS contamination in tap water: Target and suspect screening of zwitterionic, cationic, and anionic species across Canada and beyond by Termeh Teymoorian, Gabriel Munoz, Sébastien Sauvé

“…Between 2021–2023, an expanded list of 76 target PFAS was screened in tap water samples mainly from Canada, but also including tap water samples from the Eastern United States, Mexico, South America (Argentina), the Caribbean (Dominican Republic, Cuba), Africa (Algeria, Cameroon, Central African Republic, Morocco, Rwanda, Tunisia), Europe (France, Greece, Italy, Spain, and the United Kingdom) and Asia (Japan, Vietnam, Iran, and Türkiye). …”
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Uveitis and blindness in a closed herd of Equidae following leptospiral infection by J. Gerras, K. Young, D. Roberts, G. Waldman, J. H. Salmon, B. C. Gilger

“…ObjectiveTo describe the ocular findings, chronology of disease, and serum leptospiral titers in a group of horses, mules, and donkeys following an outbreak of leptospirosis.MethodsFifty Equidae in central North Carolina had ophthalmic examinations and serum leptospiral microscopic agglutination test (MAT) titers performed every 3–6 months for 24 months followed by a final examination at 34 months.ResultsThroughout the nearly three-year study period, 17 horses (34%; 17/49 horses) developed signs of uveitis; 20 eyes (20/34; 58.8%) of these 17 horses were visual at the initial examination, but only four eyes (11.8%) remained visual at the final examination. …”
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Towards consensus: defining and supporting a professional role for pharmacists associated with traditional and complementary medicines – a protocol of implementing an international... by Joanna E Harnett, Carolina Oi Lam Ung, Shane Desselle

“…Survey responses to statements about the relevance of T&CM to day-to-day practice; opinions about the bioethical and practice responsibilities; and support required to build their scope of practice associated with T&CM will be collected centrally via the online survey platform Survey Monkey and analysed using the Statistical Package for Social Sciences V.27 software for Windows. …”
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Formulation of Ebastine Fast-Disintegrating Tablet Using Coprocessed Superdisintegrants and Evaluation of Quality Control Parameters by Bhawana Dhakal, Jaybir Kumar Thakur, Reema Kumari Mahato, Ishwori Rawat, D. C. Rabin, Rahul Rana Chhetri, Kedar Prasad Shah, Atul Adhikari, Jitendra Pandey

“…Initially, fifteen trial batches of ebastine orodispersible tablets were outlined using the central composite design of Minitab software. The tablets were formulated by the direct compression method. …”
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Factors influencing type 2 diabetes self-management practices in rural Bangladesh: a qualitative investigation by Hasina Akhter Chowdhury, Hasina Akhter Chowdhury, Baki Billah, Shamia Akther Dipa, Ashraful Kabir, A. K. M. Fazlur Rahman, Liaquat Ali, Anju E. Joham, Anju E. Joham, Cheryce L. Harrison, Cheryce L. Harrison

“…Rural Bangladeshis prefer programs delivered at community clinics, viewing them as reliable, culturally appropriate central ‘hubs’ to assemble.ConclusionBarriers to and facilitators of DSMP were identified, and preferences for intervention design and delivery for implementing DSMP were explored. …”
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Clothianidin and Thiacloprid Mixture Administration Induces Degenerative Damage in the Dentate Gyrus and Alteration in Short-Term Memory in Rats by Alejandra Mora-Gutiérrez, Jorge Guevara, Carmen Rubio, Minerva Calvillo-Velasco, Daniela Silva-Adaya, Socorro Retana-Márquez, Blanca Espinosa, Carmen Martínez-Valenzuela, Moisés Rubio-Osornio

“…Neonicotinoids are pesticides that act as agonists of nicotinic receptors for acetylcholine in insects’ central nervous system (CNS). Chronic exposure to neonicotinoids in humans is related to autism, memory loss, and finger tremor. …”
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Skull vibration induced nystagmus, velocity storage and self-stability by Ian S. Curthoys, David S. Zee, Georges Dumas, Georges Dumas, Christopher J. Pastras, Julia Dlugaiczyk

“…There are two pathways conveying neural information from the vestibular periphery (the semicircular canals and the otoliths) to central neural mechanisms—a direct and an indirect pathway. …”
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MeHg Causes Ultrastructural Changes in Mitochondria and Autophagy in the Spinal Cord Cells of Chicken Embryo by Fabiana F. Ferreira, Evelise M. Nazari, Yara M. R. Müller

“…Methylmercury (MeHg) is a known neurodevelopmental toxicant, which causes changes in various structures of the central nervous system (CNS). However, ultrastructural studies of its effects on the developing CNS are still scarce. …”
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The case of Kinsburn’s Encephalopathy in a child with neuroblastoma of posterior mediastinum by T.I. Stetsenko, H.M. Fedushka, S.O. Rebenkov, T.P. Ivanova

“…Opsoclonus-myoclonus-ataxia syndrome (OMAS) is an autoimmune rare disease of the central nervous system with lesion of the cerebellum and its ligaments. …”
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Factores de riesgo cardiovascular en pacientes neuropsiquiátricos con hipertensión arterial en un servicio ambulatorio de un hospital especializado by Francisco Barrera-Guarderas, Carlos Vásquez-Salgado

“…Se utilizaron medidas de tendencia central y pruebas de asociación, con IC95%. Resultados: Edad promedio 56.48 (± 13.51) años, predominan las mujeres, tendencia a obesidad (IMC 31.60 ± 5.51), hipertrigliceridemia (183.96 ± 97.63 mg/dl) y c-HDL disminuido (38.4 ± 18.53 mg/dl). …”
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Double-blind, randomised, placebo-controlled trial to evaluate the effectiveness of late gestation oral melatonin supplementation in reducing induction of labour rates in nulliparo... by Miranda Davies-Tuck, Emily Callander, Mary Sharp, Scott W White, Dorota A Doherty, Jane Warland, Zoe Bradfield, Lesley Kuliukas, Monique Rose, Amber Pettitt, Kylie Ekin, JA Keelan

“…All data will be analysed by intention to treat.Ethics and dissemination The study is approved by the Western Australia Health Central Human Research Ethics Committee (RGS0000006283). …”
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Can urban compactness improve ecosystem services: Evidence from Chinese urban agglomerations by Xuewei Zhang, Jiahui Wu, Jintao Yuan, Wanxu Chen

“…Our findings revealed that the urban compactness of UAs in China generally increased from 2010 to 2020, with the most significant increases observed in the Yangtze River Delta, Mid-Yangtze River, and Central Plains UAs. The GY and HQ’s global Moran’s I for urban compactness were significantly negative, while that between CS and urban compactness was significantly positive in 2010 and negative in 2020. …”
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Genomic insights into population dynamics and adaptive strategies of the endangered dipterocarp, Hopea chinensis by Wei-Min Xiang, Yu-Ting Jiang, Jie Zou, Yan Deng, Kai Jiang, Kai-Jian Zhang, Xin-Yu Zhou, Kai-Xi Quan, Zi-Wen Han, Wei-Chao Liu, Liang Tang, Yuan-Yuan Li, Simon T. Segar, Yuan-Ye Zhang, Xing-Hua Hu, Rong Wang, Xiao-Yong Chen

“…Thus, protecting endangered dipterocarp species living on the distribution boundary of dipterocarps is a central factor in maintaining the range of Asian rainforests. …”
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CRISIS OF TRUST IN GOVERNMENT: THE ROLE OF PUBLIC RELATIONS IN ITS RESTORATION by Larysa Samoilenko, Viacheslav Sharyi, Alina Zahrebelna

“…PR professionals play a central role in this dynamic, as they are tasked with shaping and broadcasting messages that align with the needs and expectations of citizens. …”
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