Scalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties by Selin Akpinar Adscheid, Marta Rojas-Rodríguez, Salma M. Abdel-Hafez, Francesco S. Pavone, Marc Schneider, Akif E. Türeli, Martino Calamai, Nazende Günday-Türeli

“…<b>Background and Objectives</b>: Drug delivery systems (DDSs) offer efficient treatment solutions to challenging diseases such as central nervous system (CNS) diseases by bypassing biological barriers such as the blood–brain barrier (BBB). …”
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Monitoring Implementation Impact of the EU-Indonesia’s VPA on SME Livelihood by Rahmanta Setiahadi, S. R. Kartika Sari, Ahmad Maryudi, Julia Kalmirah, Liliana Baskorowati

“…Methodology survey with focus group discussions, structured interviews, and semistructured interviews to find out the response and opinion of SME’s owner and employee addressed the effect of SVLK in East Java and Central Java, Indonesia. The theory of change (ToC) was used to consider the implications of SVLK implementation on the sustainable livelihood of small and medium enterprises (SME’s). …”
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Impacts of Climatic Change on Reference Crop Evapotranspiration across Different Climatic Zones of Ningxia at Multi-Time Scales from 1957 to 2018 by Ziyang Zhao, Hongrui Wang, Cheng Wang, Wangcheng Li, Hao Chen, Shuxin Gong

“…In this study, the climate factors temporal trends, the spatiotemporal variation, and the climate driving factors of ET0 at different time scales were evaluated across the Northern Yellow River Irrigation Area (NYR), Central Arid Zone (CAZ), and Southern Mountain Area (SMA) of Ningxia based on 20 climatic stations’ daily data from 1957 to 2018. …”
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Clinical predictors of therapeutic laparotomy in anterior abdominal stab injuries: a multicenter study from low-income institutions in Ethiopia by Segni Kejela, Abel Hedato, Yeabsera Mekonnen Duguma, Meklit Solomon Gebremariam

“…Methods This multicenter retrospective study involved three of the largest academic medical centers in central Ethiopia. All patients who sustained an anterior abdominal stab injury and underwent exploratory laparotomy, regardless of the intraoperative findings, were included over the 3-year course of the study. …”
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Adherence to Mediterranean-Like Dietary Pattern in Association with Gastroesophageal Reflux Disease in Adolescents by Azam AhmadiVasmehjani, Sara Beigrezaei, Zahra Nafei, Nasrin Behniafard, Zahra Darabi, Amin Salehi-Abargouei, Majid Aflatoonian

“…This study aimed to examine the relationship between an adherence to Mediterranean-like dietary pattern and GERD in a large group of adolescents from central Iran. Methods: This cross-sectional study involved 5141 adolescents aged 13-14 years. …”
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The impact of death and caring for the dying and their families on surgeons - an AI assisted systematic scoping review by Jun Rong Tan, Yun Ting Ong, Victoria Jia En Fam, Annushkha Sinnathamby, Nila Ravindran, Yaoyi Ng, Lalit Kumar Radha Krishna

“…Abstract Context Surgeons are taking central roles in caring for patients leaving them prone to the emotional turmoil and grief of patients and families and the moral, psychological and existential distress of members of the interprofessional team and trainees. …”
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Diagnostic performance of artificial intelligence in detection of renal cell carcinoma: a systematic review and meta-analysis by Mahdi Gouravani, Mohammad Shahrabi Farahani, Mohammad Amin Salehi, Shayan Shojaei, Sina Mirakhori, Hamid Harandi, Soheil Mohammadi, Ramy R. Saleh

“…Materials and methods PubMed, Scopus, CENTRAL, and Embase electronic databases were systematically searched in November 2024 to identify studies that applied AI for the detection or classification of RCC. …”
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Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice by Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang

“…Activated microglia in the central nervous system (CNS) and infiltration of peripheral immune cells contribute to dopaminergic neuron loss. …”
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The value-for-money assessment and funding arrangements for high-priced drugs in an era of uncertainty: a comparative analysis of national health technology assessment agencies in... by Jihyung Hong, Eun-Young Bae, Sohee Cha, Joohyun Lee

“…This study assessed how these high-priced drugs with limited evidence were appraised and introduced in South Korea, England, Australia, and Canada, where cost-effectiveness analysis (CEA) generally plays a central role in pricing and reimbursement decisions. …”
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Results of scientific expedition to natural biotopes of the Republic of Tyva in 2019 with the purpose of infectious disease monitoring in wild bird populations by M. S. Volkov, V. N. Irza, A. V. Varkentin, S. V. Rogolyov, A. V. Andriyasov

“…The Uvs Nuur Lake is a kind of an indicator for avian influenza introduction to the Russian Federation, because this is the resting and nesting area for many migratory wild birds during the period of mass migrations from Central and South-East Asian countries. In the process of active monitoring the complete autopsy of bird carcasses with description of organs and systems and sampling for laboratory diagnostics were performed. …”
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Role of brain tissue oxygenation (PbtO2) in the management of subarachnoid haemorrhage: a scoping review protocol by Mauro Oddo, Fabio Silvio Taccone, Marco Fiore, Jacques Creteur, Elisa Bogossian

“…The literature search will be performed using several databases: Medline, EMBASE, the Cochrane Central Register of Controlled Trials and Grey literature. …”
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Neuroplasticidad en adolescente con agenesia del cuerpo calloso asociado a epilepsia by Dámaris González Vidal, Osvaldo Ramón Aguilera Pacheco, Margarita Isabel Chávez Isla

“…La agenesia del cuerpo calloso es una malformación del sistema nervioso central que se produce por falta del desarrollo o del entrecruzamiento de los axones provenientes de la corteza cerebral, lo que puede asociarse a otras malformaciones o ser producto de lesiones destructivas con atrofia. …”
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The Links Between Community-Based Financial Inclusion and Household Food Availability: Evidence from Mozambique by Aweke Tadesse, Kenan Li, Jesse Helton, Jin Huang, David Ansong

“…Using program data from central Mozambique, this study examined whether low-income women’s participation in VSLGs directly increases household food availability, as well as indirectly through increased asset ownership. …”
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Prevalence of Hypertension and Associated Factors among Residents Aged ≥18 Years in Ganzhou, China: A Cross-Sectional Study by Junwang Gu, Qi Wang, Wei Qiu, Fen Lin, Chunmei Wu, Ming Hao, Ping Wu

“…The elderly (odds ratio [95% CI]: 2.791 [2.594–3.004]), men (1.805 [1.583–2.058]), lower educated (0.848 [0.805–0.893]), a family history of hypertension (4.575 [3.900–5.368]), higher body mass index (1.344 [1.215–1.488]), central obesity (1.532 [1.304–1.799]), and less vegetable intake (1.150 [1.023–1.294]) were the major risk factors for hypertension. …”
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Coupling analysis of multi-systems urbanization: Evidence from China by Junqiang Luo, Weijing Ma, Shuang An, Zining Zhang, Yanchuan Fu, Hejun Huang, Genying Chang

“…Highly coordinated cities are primarily distributed in the core city’s radiation circles, coastal economic belts, provincial capitals in the central and western regions, and northern industrial city zones. …”
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Corneal Safety and Stability in Cases of Small Incision Lenticule Extraction with Collagen Cross-Linking (SMILE Xtra) by Ihab Mohamed Osman, Hany Ahmed Helaly, Mohsen Abou Shousha, Amir AbouSamra, Islam Ahmed

“…Outcome data were recorded including uncorrected distance visual acuity and corrected distance visual acuity (UDVA and CDVA), manifest refraction spherical equivalent (MRSE), central corneal thickness, average keratometry, endothelial cell density, corneal resistance factor (CRF), and corneal densitometry. …”
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Experimental and simulation study on tensile mechanical characteristics and crack development law of sandstone after thermal treatment by Jing Yang, Sheng-Qi Yang, Guang-Jian Liu, Bo-Wen Sun, Wen-Ling Tian, Jin-Zhou Tang

“…Based on scanning electron microscopy (SEM), X-ray diffraction (XRD) tests, it is determined that the thermal cracks in the rock show the characteristics of ''disorderly distribution, centralized development, a large number of microcracks develop to form penetration trend, and local penetration to form complex crack network''. …”
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Driving force analysis and multi-scenario simulation of landscape ecological risk in the Jianghan Plain, China by Heng Liu, Lu Zhou, Diwei Tang

“…The spatial pattern was high in the southeast and low in the central and northern areas. (3) The spatiotemporal patterns of LER resulted from the combined effect of multiple factors and were mainly influenced by the natural environment, of which the NDVI was the first dominant factor. (4) The land use intensity was higher in the natural and economic development scenarios than in the cropland and ecological protection scenarios, and the predicted LER in 2030 was higher in the former than in the latter two. …”
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Game target‐group: Implementing inhomogeneous Poisson point process to estimate animal abundance from harvest data by Javier Fernández‐López, Pelayo Acevedo, Sonia Illanas, Jose Antonio Blanco‐Aguiar, Joaquín Vicente, Olivier Gimenez

“…We conducted a simulation study to explore model performance and parameter identifiability under different scenarios (sample size, species catchability/abundance and unmodelled heterogeneity) and assessed the method on a real case study with four species in central Spain. The simulation study confirmed that with a large enough sample size (n > 5000), high catchability and lack of unmodelled heterogeneity in the abundance process, the model was able to obtain unbiased estimations for total abundance parameters. …”
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The association between body roundness index and new-onset hyperuricemia in Chinese population: the Kailuan cohort study by Xi Cai, Naihui Zhao, Xuemei Yang, Jiajia Ma, Yajing Liang, Yicheng Liao, Ruiyue Liu, Xinran Wen, Shuohua Chen, Guodong Wang, Na Li, Shouling Wu, Liufu Cui

“…Abstract Background This study aimed to investigate the potential relationship between the newly defined adiposity metric, the Body Roundness Index (BRI), which assesses central obesity, and the development of new-onset hyperuricemia. …”
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