A core set of risk factors in individuals at risk of rheumatoid arthritis: a systematic literature review informing the EULAR points to consider for conducting clinical trials and... by Daniel Aletaha, Kulveer Mankia, Paul Emery, Deshire Alpizar-Rodriguez, Andreas Kerschbaumer, Andrea Di Matteo, Heidi Siddle, Joel Kerry

“…A core set of risk factors for clinical arthritis development has not been defined.Methods A literature search and systematic literature review (SLR) was conducted to identify risk factors in individuals at risk of RA using Medline, Embase, PubMed and Central databases.Results 3854 articles were identified by the literature search. …”
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The Prevalence of Age-Related Eye Diseases and Cataract Surgery among Older Adults in the City of Lodz, Poland by Michal Szymon Nowak, Janusz Smigielski

“…To determine the prevalence of age-related eye diseases and cataract surgery among older adults in the city of Lodz, in central Poland. Material and Methods. The study design was cross-sectional and observational study. …”
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Th17/Treg balance is regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides via the microbiota-gut-brain axis by Jinyun Ma, Xiaojun Liu, Yan Zhao, Qijin Lu, Guiqing Ding, Yuanhua Wang, Xiaodong Cheng

“…The Th17/Treg imbalance is an important cause of immune cell infiltration into the central nervous system (CNS) in multiple sclerosis (MS). …”
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Enhancing global model accuracy in federated learning with deep neuro-fuzzy clustering cyclic algorithm by Chin-Feng Lai, Ying-Hsun Lai, Ming-Chin Kao, Mu-Yen Chen

“…According to experimental results, the proposed deep neuro-fuzzy clustered cyclic algorithm outperforms methods such as FedAvg, FedProx, and CyclicFL on various non-IID datasets, with accuracy approaching that of centralized learning in certain experiments. This indicates that the deep neural fuzzy methods and clustering cyclic algorithm DNCC presented in this study can improve the accuracy of global models, especially in increasingly non-IID scenarios. …”
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Assessing recovery time of ecosystems in China: insights into flash drought impacts on gross primary productivity by M. Lu, M. Lu, H. Sun, H. Sun, H. Sun, Y. Yang, J. Xue, H. Ling, H. Zhang, W. Zhang

“…The results reveal that the average recovery time across China is approximately 37.5 d, with central and southern regions experiencing the longest durations. …”
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ROMANIAN PARLIAMENTARY ELECTIONS OF 2020. A CASE STUDY OF THE LEGAL FRAMEWORK AND THE CHALLENGES OF THE COVID-19 PANDEMIC by Marius-George COJOCARU

“…Romania does not have an electoral code but has a real legislative framework that is the basis for the organization of elections: laws, decisions of the government or of the Permanent Electoral Authority, or decisions of the Central Electoral Bureau. The 2020 parliamentary elections were organized on December 6th, under the special conditions generated by the SARS COV 19 pandemic. …”
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Digital markers of asthma exacerbations: a systematic review by Brenda Cokorudy, Jeff Harrison, Amy Hai Yan Chan

“…Methods A systematic search of the following databases was conducted, using key search terms relating to asthma, digital and exacerbations: Ovid MEDLINE, EMBASE, Psycinfo, Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials. Studies that aimed to explore the relationship between any digitally measured marker and asthma exacerbations using any form of portable digital sensor technology were included. …”
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Advanced Machine Learning and Deep Learning Approaches for Estimating the Remaining Life of EV Batteries—A Review by Daniel H. de la Iglesia, Carlos Chinchilla Corbacho, Jorge Zakour Dib, Vidal Alonso-Secades, Alfonso J. López Rivero

“…By synthesizing current knowledge, identifying key research directions, and suggesting methodological improvements, this review serves as a central guide for researchers and practitioners in the rapidly evolving field of EV battery management. …”
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p97 Inhibitors Possessing Antiviral Activity Against SARS-CoV-2 and Low Cytotoxicity by Rui Ding, Tiffany C. Edwards, Prithwish Goswami, Daniel J. Wilson, Christine D. Dreis, Yihong Ye, Robert J. Geraghty, Liqiang Chen

“…<b>Methods:</b> We designed and synthesized novel p97 inhibitors based on the rearrangement of the central fused ring of our previously reported p97 inhibitors. …”
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Clinical Phenotype of Fucosidosis in Cuba by Víctor Jesús Tamayo Chang, George Alberto Pérez Benítez

“…The arithmetic mean was used as a statistician of central tendency and as a statistician of dispersion: the standard deviation. …”
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Quantitative Proteomics Analysis Reveals XDH Related with Ovarian Oxidative Stress Involved in Broodiness of Geese by Ning Zhou, Yaoyao Zhang, Youluan Jiang, Wang Gu, Shuai Zhao, Wanwipa Vongsangnak, Yang Zhang, Qi Xu, Yu Zhang

“…Additionally, proteomic analysis identified 703 differentially expressed proteins (DEPs), primarily concentrated in the GO categories of the biological process (biological regulation, response to stimulus, etc.) and enriched in the KEGG pathways (PI3K-Akt signaling pathway, etc.). Among them, XDH was central to the regulatory network. Furthermore, Western blotting revealed higher expression of XDH in the ovaries of pre-broody geese than those of laying geese. …”
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Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations by Dominica Hudasch, Franz Felix Konen, Nora Möhn, Lea Grote-Levi, Ulrich Wurster, Gabriel Welte, Josef Conzen, Nima Mahmoudi, Thomas Skripuletz, Philipp Schwenkenbecher

“…In 5/7 patients (71%) they occurred between August to September. In addition to central nervous system involvement, all patients exhibited characteristic features of neuroborreliosis like painful meningoradiculitis or peripheral facial palsy. …”
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Simulation and response mechanism of potential geographical distribution of plateau pika Ochotona curzoniae under climate change by Yanni Song, Hainan Chong, Dawei Wang, Haijun Xiao

“…The results showed that: 1) Climate factors are the main factors changing the habitat selection of plateau pika, with the highest permutation contribution (28.5 %) and permutation importance (30.6 %) for isothermality of bio3. 2). The central and eastern parts of the QTP are potential distribution areas for plateau pika, with the current suitable area totaling 8.01 × 105 km2, accounting for 32.04 % of the QTP. 3) The suitable areas of plateau pika will gradually migrate to higher altitude areas, especially with more significant changes under high-emission scenarios (SSP370 and SSP585). 4) Human activities have relatively limited impacts on the distribution pattern of plateau pika, mainly manifested as suitability changes in some local areas. …”
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Formation of Stripped Stars from Stellar Collisions in Galactic Nuclei by Charles F. A. Gibson, Fulya Kiroğlu, James C. Lombardi Jr., Sanaea C. Rose, Hans D. Vanderzyden, Brenna Mockler, Monica Gallegos-Garcia, Kyle Kremer, Enrico Ramirez-Ruiz, Frederic A. Rasio

“…Lastly, we discuss how the extended collision products, with high central to average density ratios, can be related to repeated partial TDEs like ASASSN-14ko and G objects in the Galactic center.…”
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Increased mortality risk in people with schizophrenia in Lithuania 2001–2020 by Mingaile Drevinskaite, Auguste Kaceniene, Arunas Germanavicius, Giedre Smailyte

“…Dates of death and emigration were obtained from the Central Population Register. The standardized mortality ratios (SMRs) were calculated by dividing the observed number of deaths among patients with schizophrenia by the expected number of deaths, calculated using the national rates. …”
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“The First Wave”: The Shibanid dominance in the Lower Volga region in 1361–1367 by Grinberg M.

“…Research materials: The main written sources used in the article are Russian chronicles and late (in relation to the period of research) Chinggisid genealogical writings (mainly from Central Asia). The work of the Timurid court historian Muin al-Din Natanzi should be added. …”
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Optimizing the production and efficacy of antimicrobial bioactive compounds from Streptomyces kanamyceticus in combating multi-drug-resistant pathogens by Zifang Shang, Vipasha Sharma, Liu Pai, Tarun Kumar, Sandip Patil, Sandip Patil

“…Optimization of bioactive compound production was performed using a Central Composite Design (CCD) coupled with Partial Least Squares Regression (PLSR).ResultsA total of 25 distinct Streptomyces strains were isolated, with seven confirmed as S. kanamyceticus. …”
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THE PROBLEM OF TERRITORIAL ZONING OF THE RUSSIAN FEDERATION: DOMESTIC AND INTERNATIONAL ASPECTS by V. A. Gorbanyov, B. I. Kochurov

“…We carved out ten such regions: Stolichny, Central, European North, European South, North Caucasian, Uralo-Povolzhsky, West Siberian, North Siberian, South Siberian and Far Eastern.The authors collected statistical information of land area, population size and density, physical and geographical conditions, natural resources and economic activities for each district. …”
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Ocular Biometric and Optical Coherence Tomography Parameters in Former Preterm Children: A Cohort Study by Marzieh Najjaran, Siamak Zarei-Ghanavati, Hadi Ostadimoghaddam, Abbasali Yekta, Nasser Shoeibi, Armin Hemmati, Mojtaba Abrishami, Saeed Akhlaghi, Mohammed Ziaei

“…Axial length was significantly shorter, and the cornea was steeper in both ROP groups than in other groups (p=0.001, p<0.001, respectively). The central macular thickness was significantly thicker in the treated, regressed ROP and preterm groups than in full-term children (p<0.001). …”
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Size effect-based improved antioxidant activity of selenium nanoparticles regulating Anti-PI3K-mTOR and Ras-MEK pathways for treating spinal cord injury to avoid hormone shock-indu... by Peixin Liu, Xiaodong Liu, Zihao Wu, Kui Shen, Zhaofeng Li, Xiaowei Li, Qifeng Wu, Leung Chan, Zhong Zhang, Yutong Wu, Liwen Liu, Tianfeng Chen, Yi Qin

“…Abstract Spinal cord injury (SCI) is a critical condition affecting the central nervous system that often has permanent and debilitating consequences, including secondary injuries. …”
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