Evidence for spinal disinhibition as a pain-generating mechanism in fibromyalgia syndrome by Anne Marshall, Jamie Burgess, Andreas Goebel, Bernhard Frank, Uazman Alam, Andrew Marshall

“…Identifying people with impairment of central pain processing at an early stage may provide opportunities for targeted mechanistically directed interventions. …”
Get full text

¿Lo que pasó en Ciespal¿ Apuntes etnográficos sobre el poder, los medios y los sin-sentidos de la violencia by Hurtado Arroba, Edison

“…Frente al cúmulo de representaciones y estigmatizaciones que se han tejido, y que tienen que ver con una lucha política por definir la situación, el texto reconstruye tres perspectivas paralelas: a) una institucional en donde el poder se reacomoda, b) una del sinsentido, donde la violencia se estigmatiza, y c) una fenomenológica, donde los actores se guían por una lógica de la práctica. El argumento central se construye a partir de la relación entre violencia y política: explica que las actitudes violentas de los manifestantes, lejos de ser irracionales o caóticas, como las ha visto la prensa, estuvieron cargadas de un una racionalidad práctico-moral, una profunda indignación de la población contra los políticos. …”
Get full text

Developing teachers’ competency for inclusive education in Ethiopia by Aschalew T. Kebede, Tlakale N. Phasha

“…Background: In light of the increasing diversity within school populations globally, a pressing need arises for nations to prioritise the enhancement of teachers’ competencies in implementing inclusive education, recognising the central role teacher education programmes play in addressing this imperative. …”
Get full text

Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X by Melanie P. Muller, Alex Mortenson, Josepha C. Sedzro, Po-Chao Wen, James H. Morrissey, Emad Tajkhorshid

“…The TF exosite makes substantial contacts with both the FX- and FVIIa-GLA domains, in which TF residue K165 engages directly with the FVIIa-GLA domain, whereas K166 plays a central role in binding to the FX-GLA domain. These findings underscore the substrate-binding exosite of TF as being pivotal in the formation of the EC, serving as a critical interface linking the GLA domains of both FVIIa and FX.…”
Get full text

Beyond traditional teaching: a systematic review of innovative pedagogical practices in higher education [version 2; peer review: 1 approved, 2 approved with reservations, 1 not ap... by Josefina Amanda Suyo-Vega, Monica Elisa Meneses-La-Riva, Víctor Hugo Fernández-Bedoya

“…Our primary research question guiding this investigation was: “What innovative pedagogical practices have been developed in university settings to improve teaching and learning effectiveness?” This central question led us to delve deeply into the strategies utilized, pedagogical approaches adopted, and the noticeable impact achieved after their implementation. …”
Get full text

Caracterización clínica de pacientes con esclerosis múltiple by Roberto Luis Lotti Mesa, Liudmila Gutiérrez Gacel, Fidel Jesús Moreno-Cubela

“… Introducción: La esclerosis múltiple es una enfermedad autoinmune, inflamatoria, desmielinizante, crónica, del sistema nervioso central. Supone la primera causa de discapacidad no traumática en adultos jóvenes; afecta de forma significativa la calidad de vida de los pacientes, con alteraciones físicas, sociales y emocionales. …”
Get full text

Different immunological characteristics of asymptomatic and symptomatic COVID-19 patients without vaccination in the acute and convalescence stages by Li Li, Xin Zhang, Huimin Yan, Muwei Dai, Huixia Gao, Yuling Wang, Ping Jiang, Erhei Dai

“…Further analysis of the subsets of major immune cell types in COVID-19 patients with different clinical presentations in different stages showed that in the acute stages of disease progression, the T helper cell 1 (Th1), IgD+ B and neutrophil subsets increased in COVID-19 patients, especially in symptomatic patients, while the central memory CD4+T cells (CD4 TCM), mucosa-associated invariant T (MAIT) and NK cell subsets decreased significantly, especially in symptomatic patients. …”
Get full text

Healthcare needs among unaccompanied minor refugees: a study protocol of a qualitative study explaining access and utilisation across place and gender by Matthias Richter, Jacob Spallek, Hanna-Sophie Ulrich, Emma Kohler, Eva-Maria Fach, Martin Mlinarić

“…The aims of this gender-sensitive qualitative study will be to build on the existing body of literature and to provide qualitative evidence on the contexts and mechanisms of PSC for male and female UMRs in Germany by comparing two German regions.Methods and analysis Following the study preparing realist review, a qualitative study will be undertaken in Berlin and Central German cities. Approximately 24 experts from the field of PSC and 12 lay UMRs will participate in face-to-face, semistructured interviews. …”
Get full text

Influence of preoperative frailty on quality of life after cardiac surgery: Protocol for a systematic review and meta-analysis. by Kathryn Bezzina, Christophe A Fehlmann, Ming Hao Guo, Sarah M Visintini, Fraser D Rubens, George A Wells, Rosetta Mazzola, Caroline McGuinty, Allen Huang, Lara Khoury, Kevin Emery Boczar

“…Studies will be retrieved from major databases including the Cochrane Central Register of Controlled Trials, Embase, and Medline. …”
Get full text

Acute effects of physical exercise on cognitive function and neurotrophins in patients with type 1 diabetes: A systematic review by Emanuele Zanardo, Giulia Quinto, Francesca Battista, Federica Duregon, Marco Vecchiato, Chiara Bergia, Kirk Erickson, Andrea Ermolao, Daniel Neunhaeuserer

“…Methods: MEDLINE, Cochrane Library (CENTRAL database), EMBASE and SPORTDiscus were screened by 2 independent reviewers, who selected studies that analysed acute effects of physical exercise in patients with T1DM on BDNF levels or cognitive function tests before and after exercise. …”
Get full text

Gambaran Castelli’s Risk Index-1 pada Pasien Sindrom Koroner Akut di RSUP Dr. M. Djamil Padang by Eka Musmita Sabebegen, Rismawati Yaswir, Efrida Efrida

“…Methods: This descriptive study was carried out in the central laboratory and the CardioVascular Care Unit (CVCU) of Dr. …”
Get full text

Optimization of Medium Composition and Fluidized Bed Drying Conditions for Efficient Production of Dry Yeast by Hyun-Jin Kang, Hwan Hee Yu, Chang-Won Cho, Young Kyung Rhee, Tae-Wan Kim, Young-Wook Chin

“…Muscovado and corn steep liquor were used as the carbon and nitrogen sources, respectively, and their optimal concentrations were identified using response surface methodology for efficient cultivation of <i>Saccharomyces cerevisiae</i> ReY4-7 isolated from <i>nuruk</i>. Central composite design analysis revealed that the optimal medium composition was 146.12 g/L muscovado and 58.68 g/L corn steep liquor. …”
Get full text

Cloud-Based Transaction Fraud Detection: An In-depth Analysis of ML Algorithms by Ali Alhchaimi

“…Context: Cloud-based services are increasingly central in financial technology, enabling scalable and efficient transactions. …”
Get full text

Control postural estático y estabilidad del Core en deportistas de alto rendimiento by Andres Felipe Villaquiran Hurtado, Diana María Rivera Rujana, Enmanuel Fernando Portilla Dorado, Paola Vernaza Pinzón

“…Respecto al Core, se encontró un déficit en la estabilidad de la zona central, además se evidencio una relación estadísticamente significativa entre la estabilidad del core, la alineación de columna, la pelvis y el tobillo (p≤0,05) con alta magnitud de asociación. …”
Get full text

Effect of bortezomib on the treatment of multiple myeloma: a systematic review protocol by Vania dos Santos Nunes-Nogueira, Lucas Oliveira Cantadori, Rafael Dezen Gaiolla

“…General and adaptive search strategies have been created for the following electronic health databases: Embase, Medline, LILACS and CENTRAL. Two reviewers have independently selected eligible studies, will assess the risk of bias, and will extract data from the included studies. …”
Get full text

Assessing swallowing disorders in adults on high-flow nasal cannula in critical and non-critical care settings. A scoping review protocol. by Ruvistay Gutierrez-Arias, Gabriel Salgado-Maldonado, Paola Letelier Valdivia, Francisco Salinas-Barahona, Carmen Echeverría-Valdebenito, Pamela Seron, INTRehab Research Group

“…A systematic search in MEDLINE (Ovid), Embase (Ovid), CENTRAL, CINAHL (EBSCOhost), and other resources will be conducted. …”
Get full text

Is There Any Association between PEEP and Upper Extremity DVT? by Farah Al-Saffar, Ena Gupta, Furqan Siddiqi, Muhammad Faisal, Lisa M. Jones, Vandana Seeram, Mariam Louis, James D. Cury, Abubakr A. Bajwa, Adil Shujaat

“…Nineteen (67.8%) had a central venous catheter on the same side. The mean ± SD duration of MV was 13.2±9.5 days. …”
Get full text

Clinical outcomes and long-term efficacy of high tibial osteotomy in treating knee instability: An updated systematic review by Mustamsir Edi, Aji Aulia Pandu, Adiwangsa Ahmad Abdilla, Akmalizzan Azfar Ahnaf

“…Methods: A systematic literature search was conducted using Cochrane Central, PubMed, MEDLINE, and ProQuest databases for studies published between 2000 and June 2024. …”
Get full text

STATE-BUILDING PROCESS IN UZBEKISTAN: MANY MILES TO GO by Gürhan Ünal

“…InUzbekistan, transition process was operated by Islam Karimov until 2016.Contrary to some other Central Asian countries, Uzbekistan enjoyed a morestable transition process mostly due to Karimov’s authoritarian rule. …”
Get full text

Israel in Foreign Policy of the United Arab Emirates: from Confrontation to Normalization by E. S. Melkumyan

“…During this period, the Arab-Israeli conflict gradually lost its central role for the Arab world; the states of the Persian Gulf began to establish contacts with Israel, united by common fears about the strengthening Iran. …”
Get full text